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Inhalation Toxicology
International Forum for Respiratory Research
Volume 13, 2001 - Issue 8
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Research Article

TIME STUDY ON DEVELOPMENT AND REPAIR OF LUNG INJURY FOLLOWING OZONE EXPOSURE IN RATS

Pages 703-717 | Published online: 01 Oct 2008

  • Barr, B. C., Hyde, D. M., Plopper, C. G., and Dungworth, D. L. 1990. A comparison of terminal airway remodeling in chronic daily versus episodic ozone exposure. Toxicol. Appl. Pharmacol. 106: 384-407.
  • Bedi, J. F., Horvath, S. M., and Drechsler-Parks, D. M. 1989. Adaptation of older individuals repeatedly exposed to 0.45 ppm ozone for two hours. J. Air Pollut. Control Assoc. 39:194-199.
  • Chang, L. Y., Huang, Y., Stockstill, B. L., Graham, J. A., Grose, E. C., Menache, M. G., Miller, F. J., Costa, D. L., and Crapo J. D. 1992. Epithelial injury and interstitial fibrosis in the proximal alveolar regions of rats chronically exposed to a simulated pattern of urban ambient ozone. Toxicol. Appl. Pharmacol. 115:241-252.
  • Dormans, J. A. M. A., Van Bree, L, Boere, A. J. F., Marra, M., and Rombout, P. J. A. 1999. lnterspecies differences in time course of pulmonary toxicity following repeated exposure to ozone, lnhal. Toxicol. 11:309-329.
  • Doumas, B. T., and Briggs, H. G. 1972. Determination of serum albumin. In Standard methods of clinical chemistry, ed. G. R. Cooper, vol. 7, pp. 175-188. New York: Academic Press.
  • Folinsbee, L. J., McDonnell, W. F., and Horstman, D. H. 1988. Pulmonary function and symptom responses after 6.6 hour exposure to 0.12 ppm ozone with moderate exercise. J. Air Pollut. Control Assoc. 38:28-35.
  • Folinsbee, L. J., and Hazucha M. J. 1989. Persistence of ozone induced changes in lung function and airway responsiveness. In Proceedings of the third US-Dutch international symposium on atmospheric ozone research and its policy implications, eds. T. Schneider, S. D. Lee, G. J. R. Wolters, and L. D. Grant, pp. 483-492. Amsterdam: Elsevier.
  • Hatch, G. E., Stade R., Stead, A. G., and Graham, J. A. 1986. Species comparison of acute inhalation toxicity of ozone and phosgene. J. Toxicol. Environ. Health 19:43-53.
  • Hatch, G. E., Slade, R., Harris, L. P., McDonnell, W. F., Devlin, R. B., Koren, H., Costa, D. L, and McKee, J. 1994. Ozone dose and effect in humans and rats. A comparison using oxygen-18 labeling and bronchoalveolar lavage. Am. J. Respir. Crit. Care Med. 150:676-683.
  • Horstman, D. H., McDonnell, W. F., Folinsbee, L., Abdul-Salaam, S., and Ives, P. 1989. Changes in pulmonary function and airway reactivity due to prolonged exposure to typical ambient ozone levels. In Atmospheric ozone research and its policy implications, eds. T. Schneider, S. D. Lee, G. J. R. Wolters, and L. D. Grant, pp. 755-762. Amsterdam: Elsevier.
  • Last, J. A., Summers, P., and Reiser, K. M. 1989. Biosynthesis of collagen crosslinks. II. In vivo labelling and stability of lung collagen in rats. Biochim. Biophys. Acta 990:182-189.
  • Last, J. A., Gelzleichter, T., Harkema, J., Parks, W. C, and Mellick, P. 1993. Effects of 20 months of ozone exposure on lung collagen in Fischer 344 rats. Toxicology 84:83-102.
  • Lipman, J. M. 1989. Fluorophotometric quantitation of DNA in articular cartilage utilizing Hoechst 33258. Anal. Biochem. 176:128-131.
  • Lippmann, M. 1993. Health effects of tropospheric ozone: A review of recent findings and their implications to ambient air quality standards. J. Expos. Anal. Environ. Epidemiol. 3:103-129.
  • Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-275.
  • Marra, M., and Rombout, P. J. A. 1990. Design and performance of an inhalation chamber for exposing laboratory animals to oxidant air pollutants, lnhal. Toxicol. 2:187-204.
  • McDonnell, W. F. 1991. Intersubject variability in human acute ozone responses. Pharmacogenetics 1:110-113.
  • Miller, F. 1995. Uptake and fate of ozone in the respiratory tract. Toxicol. Lett. 82-83:277-285.
  • Mills, P. R., Davies, R. J., and Devalia, J. L. 1999. Airway epithelial cells, cytokines, and pollutants. Am. J. Respir. Crit. Care Med. 160:538-543.
  • Mustafa, M. G. Hacker, A. D., Ospital, J. J., Hussain, M. Z., and Lee, S. D. 1977. Biochemical effects of environmental oxidant pollutants in animal lungs. In Biochemical effects of environmental pollutants, ed. S. D. Lee, pp. 59-96. Ann Arbor, Ml: Ann Arbor Science.
  • Plopper, C. G., Chu, F. P., Haselton, C. J., Peake, J., Wu, J., and Pinkerton, K. E. 1994. Dose-dependent tolerance to ozone: I. Tracheobronchial epithelial reorganization in rats after 20 months' exposure. Am. J. Pathol. 144:404-420.
  • Rennard, S. I. 1999. Inflammation and repair processes in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 160:S12-S16.
  • Tager, I. B., Kunzli, N., Ngo, L., and Balmes, J. 1998. Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part 1: Variability of pulmonary function measures. Res. Rep. Health Effects lnst. 81:1-25.
  • Tepper, J. S., Costa, D. L., Lehman, J. R., Weber, M. F., and Hatch, G. E. 1989. Unattenuated structural and biochemical alterations in the rat lung during functional adaptation to ozone. Am. Rev. Respir. Dis. 140:493-501.
  • Tyler, W. S. 1983. Comparative subgross anatomy of lungs: pleuras, interlobular septa, and distal airways. Am. Rev. Respir. Dis. 128:532-536.
  • U.S. Environmental Protection Agency. 1996. Air Quality Criteria for Ozone and Related Photochemical Oxidants. EPA/600/P-93/004aF. Washington DC: U.S. Environmental Protection Agency, Office for Research and Development.
  • Van Bree, L., and Last, J. A. 1997. Ozone. In Comprehensive toxicology, eds. I. G. Sipes, C. A. McQueen, and J. A. Gandolfi, vol. 8, Toxicology of the respiratory system, pp. 265-274. New York: Elsevier Science.
  • Van Bree, L., Rombout, P. J. A., Rietjens, I. M. C. M., Dormans, J. A. M. A., and Marra, M. 1989. Pathobiochemical effects in rat lung related to episodic ozone exposure. In Atmospheric ozone research and its policy implications, eds. T. Schneider, S. D. Lee, G. J. R. Wolters and L. D. Grant, pp. 723-732. Amsterdam: Elsevier.
  • Van Bree, L., Marra, M., Dormans, J. A. M. A., and Rombout, P. J. A. 1992. Lung injury during acute and subchronic ozone exposure and recovery. A correlated biochemical and morphological study on inflammation, structural changes and collagen content. Am. Rev. Respir. Dis. 145-9:A93.
  • Woesner, J. F., Jr. 1961. The determination of hydroxyproline in tissue and protein samples containing small proportions of this amino acid. Arch. Biochem. Biophys. 93:440-447.

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