Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 14, 2002 - Issue 5
29
Views
13
CrossRef citations to date
0
Altmetric
Research Article

EFFECTS OF AEROSOLS FROM NONTOXIC Stachybotrys chartarum ON MURINE AIRWAYS

, , , , &
Pages 521-540 | Published online: 01 Oct 2008

  • Abbas, A. K., Murphy, K. M., and Sher, A. 1996. Functional diversity of helper T lymphocytes. Nature 383:787-793.
  • Alarie, Y. 1998. Computer-based bioassay for evaluation of sensory irritation of airborne chemicals and its I im it of detection. Arch. Toxicol. 72:277-282.
  • American Society for Testing and Materials. 1984. Standard test method for estimating sensory irritancy of airborne chemicals. Designation E 981-84. Philadelphia: ASTM.
  • Andersson, M. A., Nikulin, M., Köljalg, U., Andersson, M. C., Rainey, F., Reijula, K., Hintikka, E.-L, and Salkinoja-Salonen, M. 1997. Bacteria, molds, and toxins in water-damaged building materials. Appl. Environ. Microbiol. 63:387-393.
  • Björnsson, E., Norbäck, D., Janson, C, Widström, J., Palmgren, U., Ström, G., and Boman, G. 1995. Asthmatic symptoms and indoor levels of micro-organisms and house dust mites. Clin. Exp. Allergy 2 5:423-431.
  • Blease, K., Mehrad, B., Standiford, T. J., Lukacs, N. W., Gosling, J., Boring, L., Charo, I. F., Kunkel, S. L., and Hogaboam, C. M. 2000. Enhanced pulmonary allergic responses to Aspergillus in CCR2-/-mice.J. ImmunoL 165:2603-2611.
  • Boylstein, L. A., Andersson, S. J., Thompson, R. D., and Alarie, Y. 1995. Characterization of the effects of an airborne mixture of chemicals on the respiratory tract and smoothing polynomial spline analysis of the data. Arch. Toxicol. 69:579-589.
  • Boylstein, L. A., Luo, J., Stock, M. F., and Alarie, Y. 1996. An attempt to define a just detectable effect for airborne chemicals on the respiratory tract in mice. Arch. Toxicol. 70:567-578.
  • Brunekreef, B., Dockery, D. W., Speizer, F. E., Ware, J. H., Spengler, J. D., and Ferris, B. G. 1989. Home dampness and respiratory morbidity in children. Am. Rev. Respir. Dis. 140:1363-1367.
  • Coffman, R. L., Chatelain, R., Leal, L. M., and Varkila, K. 1991. Leishmania major infection in mice: A model system for the study of CD4+ T-cell subset differentiation. Res. ImmunoL 142:36-40.
  • Coffman, R. L., Lebman, D. A., and Rothman, P. 1993. Mechanism and regulation of immunoglobuMn isotype switching. Adv. ImmunoL 54:229-270.
  • Comoy, E. E., Pestel, J., Duez, C, Stewart, G. A., Vendeville, C., Fournier, C., Finkelman, F., Capron, A., and Thyphronitis, G. 1998. The house dust mite allergen, Dermatophagoides pteronyssinus, promotes type 2 responses by modulating the balance between IL-4 and IFN-?. J. ImmunoL 160:2456-2462.
  • Cooley, J. D., Wong, W. C., Jumper, C. A., and Straus, D. C. 1999. Cellular and humoral responses in an animal model inhaling Penicillium chrysogenum spores. In Bioaerosols, fungi and mycotoxins: Health effects, assessment, prevention and control, ed. E. Johanning, pp. 403-410. Albany, NY: Eastern New York Occupational and Environmental Health Center.
  • Dales, R. E., and Miller, D. 1999. Residential fungal contamination and health: Microbial cohabitants as covariates. Environ. Health Perspect. 107(suppl. 3): 481-483.
  • Domsch, K. H., and Gams, W. 1972. Fungi in agricultural soils. London: Longman.
  • Fogelmark, B., and Rylander, R. 1997. (1->3)-ß-D-glucan in some indoor air fungi. Indoor Built Environ. 6:291-294.
  • Fung, F., Clark, R., and Williams, S. 1998. Stachybotrys, a mycotoxin-producing fungus of increasing toxicologie importance. J. Toxicol. Clin. Toxicol. 36:79-86.
  • Glaab, T., Daser, A., Braun, A., Neuhaus-Steinmetz, U., Fabel, H., Alarie, Y., and Renz, H. 2001. Tidal midexpiratory flow as a measure of airway hyperresponsiveness in allergic mice. Am. J. Physiol. Lung CeII MoI. Physiol. 280:L565-L573.
  • Gravesen, S., Nielsen, P. A., Iversen, R., and Nielsen, K. F. 1999. Microfungal contamination of damp buildings-Examples of risk constructions and risk materials. Environ. Health Perspect. 107(suppl.3): 505-508.
  • Hintikka, E.-L., and Nikulin, M. 1998. Airborne mycotoxins in agricultural and indoor environments. Indoor Air Suppl. 4:66-70.
  • Hodgson, M. J., Morey, P., Leung, W.-Y., Morrow, L., Miller, D., Jarvis, B. B., Robbins, H., Halsey, J. F., and Storey, E. 1998. Building-associated pulmonary disease from exposure to Stachybotrys chartarum and Aspergillus versicolor. J. Occup. Environ. Med. 40:241-249.
  • Hogaboam, C. M., Gallinat, C. S., Taub, D. D., Strieter, R. M., Kunkel, S. L, and Lukacs, N. W. 1999. lmmunomodulabry role of C10 chemokine in a murine model of allergic bronchopul monary aspergillosis. J. ImmunoL 162:6071-6079.
  • Hogaboam, C. M., Blease, K., Mehrad, B., Steinhauser, M. L., Standiford, T. J., Kunkelm, S. L., and Lukacs, N. W. 2000. Chronic airway hyperreactivity, goblet cell hyperplasia, and peribronchial fibrosis furing allergic airway disease induced by Aspergillus fumigatus. Am. J. Pathol. 156:723732.
  • Jussila, J., Komulainen, H., Huttunen, K., Roponen, M., Hälinen, A., Hyvärinen, A., Kosma, V.-M., Pelkonen, J., and Hirvonen, M.-R. 2001. Inflammatory responses in mice after intratracheal instillation of spores of Streptomyces califomicus isolate from indoor air of a moldy building. Toxicol. Appl. Pharmacol. 171:61-69.
  • Kasanen, J.-P., Pasanen, A.-L., Pasanen, P., Liesivuori, J., Kosma, V.-M., and Alarie, Y. 1998. Stereospecificity of the sensory irritation receptor for nonreactive chemicals illustrated by pinene enantiomers. Arch. Toxicol. 72:514-523.
  • Korpi, A., Saarelainen, S., and Pasanen, A.-L. 2000. lmmunological responses to Stachybotrys chartarum antigen in mice. In Abstr. 19th Congr. European Academy of Allergology and Clinical Immunology, EAACI 2000, Lisbon 1-5 July 2000. Allergy 55(suppl. 63): 133.
  • Kurup, V. P., Seymour, B. W. P., Choi, H., and Coffman, R. L. 1994. Paniculate Aspergillus fumigatus antigens elicit a TH2 response in BALB/c mice. j. Allergy Clin. ImmunoL 93:1013-1020.
  • Kurup, V. P., Choi, H., Murali, P. S., Resnick, A., Fink, J. N., and Coffman, R. L. 1997. Role of particulate antigens of Aspergillus in murine eosinophilia. Int. Arch. Allergy ImmunoL 112:270-278.
  • Kurup, V. P., Choi, H. Y., Murali, P. S., Xia, J.-Q., Coffman, R. L., and Fink, J. N. 1999. Immune responses to Aspergillus antigen in IL-4-/- mice and the effect of eosinophil ablation. Allergy 54:420-427.
  • Lee, M.-G., Li, S., Jarvis, B. B., and Pestka, J. J. 1999. Effects of satratoxins and other macrocyclic trichothecenes on IL-2 production and viability of EL-4 tymoma cells. J. Toxicol. Environ. Health A 57:459-474.
  • Lewis, T. R., Morrow, P. E., McClellan, R. O., Raabe, O. G., Kennedy, G. L., Schweiz, B. A., Goehl, T. J., Roycroft, J. H., and Chhabra, R. S. 1989. Establishing aerosol exposure concentrations for inhalation toxicity studies. Toxicol. Appl. Pharmacol. 99:377-383.
  • Mehlhop, P. D., van de Rijn, M., Brewer, J. P., Kisselgof, A. B., Geha, R. S., Oettgen, H. C, and Martin, T. R. 2000. CD40L, but not CD40, is required for allergen-induced bronchial hyperresponsiveness in mice. Am. J. Respir. Cell MoI. Biol. 23:646-651.
  • Morgenstern, D. E., Gifford, M. A. C., Li, L. L., Doerschuk, C. M., and Dinauer, M. C. 1997. Absence of respiratory burst in x-linked chronic granulomatous disease mice leads to abnormalities in both host defence and inflammatory response to Aspergillus fumigatus. J. Exp. Med. 185:207-218.
  • Neuhaus-Steinmetz, U., Glaab, T., Daser, A., Braun, A., Lommatzsch, M., Herz, U., Kips, J., Alarie, Y., and Renz, H. 2000. Sequential development of airway hyperresponsiveness and acute airway obstruction in a mouse model of allergic inflammation. Int. Arch. Allergy ImmunoL 121:57-67.
  • Nikulin, M., Reijula, K., Jarvis, B. B., and Hintikka, E.-L. 1996. Experimental lung mycotoxicosis in mice induced by Stachybotrys atra. Int. J. Exp. Pathol. 77:213-218.
  • Nikulin, M., Reijula, K., Jarvis, B. B., Veijalainen, P., and Hintikka, E.-L. 1997. Effects of intranasal exposure to spores of Stachybotrys atra in mice. Fundam. Appl. Toxicol. 35:182-188.
  • Pasanen, A.-L., Yli-Pietilä, K., Pasanen, P., Kalliokoski, P., and Tarhanen, J. 1999. Ergosterol content in various fungal species and biocontaminated building materials. Appl. Environ. MicrobioL 65:138-142.
  • Pirhonen, I., Nevalainen, A., Husman, T., and Pekkanen, J. 1996. Home dampness, moulds and their influence on respiratory infections and symptoms in adults in Finland, Eur. Respir. J. 9:26182622.
  • Popp, J. A., and Monteiro-Riviere, N. A. 1985. Macroscopic, microscopic, and ultrastructural anatomy of the nasal cavity, Rat; the upper respiratory system (nares, larynx, trachea). In Monographs on pathology of laboratory animals, sponsored by the International Life Sciences Institute, Respiratory system, eds. T. C. Jones, U. Mohr, and R. D. Hunt, pp. 3-4. Berlin: Springer-Verlag.
  • Raabe, O. G., Al-Bayati, M. A., Teague, S. V., and Rasolt, A. 1988. Regional deposition of inhaled monodisperse coarse and fine aerosol particles in small laboratory animals. Ann. Occup. Hyg. 32(suppl. 1): 53-63.
  • Raunio, P., Kärkkäinen, M., Virtanen, T., Rautiainen, J., and Pasanen, A.-L. 2001. Preliminary description of antigenic components characteristic of Stachybotrys chartarum. Environ. Res. 85: 246-255.
  • Reiman, M., Kujanpää, L., Vilkki, R., Sundholm, P., and Kujanpää, R. 2000. Microbes in building materials of different densities. Proc. Healthy Buildings 2000, SIY Indoor Air Information Oy, Helsinki, 3:313-316.
  • Robbins, C. A., Swenson, L. J., Nealley, M. L., Cots, R. E., and Kelman, B. J. 2000. Health effects of mycotoxins in indoor air: A critical review. Appl. Occup. Environ. Hyg. 15:773-784.
  • Rylander, R. 1996. Dampness and microbial growth as risk factors for respiratory disease in indoor environments. Report 4/1996 prepared for the Swedish Board of Health and Welfare.
  • Rylander, R., and Lin, R.-H. 2000. (1->3)-ß-D-glucan-Relationship to indoor air-related symptoms, allergy and asthma. Toxicologist 152:47-52.
  • Snapper, C. M., Peschel, C, and Paul, W. E. 1988. IFN-gamma stimulates lgG2a secretion by murine B cells stimulated with bacterial lipopolysaccharide. J. ImmunoL 140:2121-2127.
  • Thorn, J., and Rylander, R. 1998. Airways inflammation and glucan in a rowhouse area. Am. J. Respir. Crit. Care Med. 157:1798-1803.
  • Thorne, P. S. 2000. Inhalation toxicology models of endotoxin- and bioaerosol-induced inflammation. Toxicologist 152:13-23.
  • van de Rijn, M., Mehlhop, P. D., Judkins, A., Rothenberg, M. E., Luster, A. D., and Oettgen, H. C. 1998. A murine model of allergic rhinitis: Studies on the role of IgE in pathogenesis and analysis of the eosinophil influx elicited by allergen and eotaxin.y. Allergy Clin. ImmunoL 102:65-74.
  • Vijayaraghavan, R., Schaper, M., Thompson, R., Stock, M. F., and Alarie, Y. 1993. Characteristic modifications of the breathing pattern of mice to evaluate the effects of airborne chemicals on the respiratory tract. Arch. Toxicol. 67:478-490.
  • Vijayaraghavan, R., Schaper, M., Thompson, R., Stock, M. F., Boylstein, L. A., Luo, J. E., and Alarie, Y. 1994. Computer assisted recognition and quantitation of the effects of airborne chemicals acting at different areas of the respiratory tract in mice. Arch. Toxicol. 68:490-499.
  • Wan, G.-H., Li, C-S., Guo, S.-P., Rylander, R., and Lin, R.-H. 1999. An airborne mold-derived product, ß-1,3-D-glucan, potentiates airway allergic responses, Eur. J. ImmunoL 29:2491-2497.
  • Wilkins, C. K., Larsen, S. T., Hammer, M., Poulsen, O. M., Wolkoff, P., and Nielsen, G. D. 1998. Respiratory effects in mice exposed to airborne emissions from Stachybotrys chartarum and implications for risk assessment. Pharmacol. Toxicol. 83:112-119.
  • Yang, G.-H., Jarvis, B. B., Chung, Y.-J., and Pestka, J. J. 2000. Apoptosis induction by the satratoxins and other trichothecene mycotoxins: Relationship to ERK, p38 MAPK, and SAPK/JNK activation. Toxicol. Appl. Pharmacol. 164:149-160.
  • Yip, H. C, Karulin, A. Y., Tary-Lehmann, M., Hesse, M. D., Radeke, H., Heeger, P. S., Trezza, R. P., Heinzel, F. P., Forsthuber, T., and Lehmann, P. V. 1999. Adjuvant-guided type-1 and type-2 immunity: Infectious/noninfectious dichotomy defines the class of response. J. ImmunoL 162: 3942-3949.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.