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Inhalation Toxicology
International Forum for Respiratory Research
Volume 16, 2004 - Issue sup1
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Research Article

Hypertensive Rats are Susceptible to TLR4-Mediated Signaling Following Exposure to Combustion Source Particulate Matter

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Pages 5-18 | Published online: 20 Oct 2008

REFERENCES

  • Aderem A., Ulevitch R. J.. 2000. Toll-like receptors in the induction of the innate immune response. Nature. 406: 782–787. [PUBMED], [INFOTRIEVE]
  • Aharinejad S., Schraufnagel D. E., Bock P., MacKay C. A., Larson E. K., Miksovsky A., Marks S. C., Jr.. 1996. Spontaneously hypertensive rats develop pulmonary hypertension and hypertrophy of pulmonary venous sphincters. Am. J. Pathol.. 148: 281–290. [PUBMED], [INFOTRIEVE]
  • Andonegui G., Bonder C. S., Green F., Mullaly S. C., Zbytnuik L., Raharjo E., Kubes P.. 2003. Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs. J. Clin. Invest.. 112: 1264, [CROSSREF]
  • Arbour N. C., Lorenz E., Schutte B. C., Zabner J., Kline J. N., Jones M., Frees K., Watt J. L., Schwartz D. A.. 2000. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat. Genet.. 25: 187–191. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Atkinson R. W., Anderson H. R., Strachan D. P., Bland J. M., Bremner S. A., Ponce de, Leon A.. 1999. Short-term associations between outdoor air pollution and visits to accident and emergency departments in London for respiratory complaints. Eur. Respir. J.. 13: 257–265. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Becker S., Fenton M. J., Soukup J. M.. 2002. Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles. Am. J. Respir. Cell Mol. Biol.. 27: 611–618. [PUBMED], [INFOTRIEVE]
  • Bosisio D., Polentarutti N., Sironi M., Bernasconi S., Miyake K., Webb G. R., Martin M. U., Mantovani A., Muzio M.. 2002. Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: A molecular basis for priming and synergism with bacterial lipopolysaccharide. Blood. 99: 3427–3431. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Castranova V., Ma J. Y., Yang H. M., Antonini J. M., Butterworth L., Barger M. W., Roberts J., Ma J. K.. 2001. Effect of exposure to diesel exhaust particles on the susceptibility of the lung to infection. Environ. Health Perspect.. 109(suppl. 4)609–612. [PUBMED], [INFOTRIEVE]
  • Chen L. Y., Zuraw B. L., Zhao M., Liu F. T., Huang S., Pan Z. K.. 2003. Involvement of protein tyrosine kinase in Toll-like receptor 4-mediated NF-kappa B activation in human peripheral blood monocytes. Am. J. Physiol. Lung Cell. Mol. Physiol.. 284: L607–613. [PUBMED], [INFOTRIEVE]
  • Costa D. L., Lehmann J. R., Harold W. M., Drew R. T.. 1986. Transoral tracheal intubation of rodents using a fiberoptic laryngoscope. Lab. Anim. Sci.. 36: 256–261. [PUBMED], [INFOTRIEVE]
  • Donaldson K., Brown D., Clouter A., Duffin R., MacNee W., Renwick L., Tran L., Stone V.. 2002. The pulmonary toxicology of ultrafine particles. J. Aerosol. Med.. 15: 213–220. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Fan J., Kapus A., Marsden P. A., Li Y. H., Oreopoulos G., Marshall J. C., Frantz S., Kelly R. A., Medzhitov R., Rotstein O. D.. 2002. Regulation of Toll-like receptor 4 expression in the lung following hemorrhagic shock and lipopolysaccharide. J. Immunol.. 168: 5252–5259. [PUBMED], [INFOTRIEVE]
  • Gilmour P. S., Rahman I., Hayashi S., Hogg J. C., Donaldson K., MacNee W.. 2001. Adenoviral E1A primes alveolar epithelial cells to PM(10)-induced transcription of interleukin-8. Am. J. Physiol. Lung Cell. Mol. Physiol.. 281: L598–606. [PUBMED], [INFOTRIEVE]
  • Gilmour P. S., Rahman I., Donaldson K., MacNee W.. 2003. Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles. Am. J. Physiol. Lung Cell. Mol. Physiol.. 284: L533–540. [PUBMED], [INFOTRIEVE]
  • Hailman E., Lichenstein H. S., Wurfel M. M., Miller D. S., Johnson D. A., Kelley M., Busse L. A., Zukowski M. M., Wright S. D.. 1994. Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14. J. Exp. Med.. 179: 269–277. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Jiang Q., Akashi S., Miyake K., Petty H. R.. 2000. Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. J. Immunol.. 165: 3541–3544. [PUBMED], [INFOTRIEVE]
  • Jimenez L. A., Drost E. M., Gilmour P. S., Rahman I., Antonicelli F., Ritchie H., MacNee W., Donaldson K.. 2002. PM(10)-exposed macrophages stimulate a proinflammatory response in lung epithelial cells via TNF-alpha. Am. J. Physiol. Lung Cell. Mol. Physiol.. 282: L237–248. [PUBMED], [INFOTRIEVE]
  • Kodavanti U. P., Costa D. L., Bromberg P. A.. 1998a. Rodent models of cardiopulmonary disease: Their potential applicability in studies of air pollutant susceptibility. Environ. Health Perspect.. 106(s1)111–130. [PUBMED], [INFOTRIEVE]
  • Kodavanti U. P., Hauser R., Christiani D. C., Meng Z. H., McGee J., Ledbetter A., Richards J., Costa D. L.. 1998b. Pulmonary responses to oil fly ash particles in the rat differ by virtue of their specific soluble metals. Toxicol. Sci.. 43: 204–212. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Kodavanti U. P., Schladweiler M. C., Richards J. R., Costa D. L.. 2001. Acute lung injury from intratracheal exposure to fugitive residual oil fly ash and its constituent metals in normo- and spontaneously hypertensive rats. Inhal. Toxicol.. 13: 37–54. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Kodavanti U. P., Schladweiler M. C., Ledbetter A. D., Hauser R., Christiani D. C., McGee J., Richards J. R., Costa D. L.. 2002a. Temporal association between pulmonary and systemic effects of particulate matter in healthy and cardiovascular compromised rats. J. Toxicol. Environ. Health A. 65: 1545–1569. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Kodavanti U. P., Schladweiler M. C., Ledbetter A. D., Hauser R., Christiani D. C., Samet J. M., McGee J., Richards J. H., Costa D. L.. 2002b. Pulmonary and systemic effects of zinc-containing emission particles in three rat strains: Multiple exposure scenarios. Toxicol. Sci.. 70: 73–85. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Le, Tertre A., Medina S., Samoli E., Forsberg B., Michelozzi P., Boumghar A., Vonk J. M., Bellini A., Atkinson R., Ayres J. G., Sunyer J., Schwartz J., Katsouyanni K.. 2002. Short-term effects of particulate air pollution on cardiovascular diseases in eight European cities. J. Epidemiol. Commun. Health. 56: 773–779. [CROSSREF]
  • Lee J. Y., Plakidas A., Lee W. H., Heikkinen A., Chanmugam P., Bray G., Hwang D. H.. 2003. Differential modulation of Toll-like receptors by fatty acids: Preferential inhibition by n-3 polyunsaturated fatty acids. J. Lipid. Res.. 44: 479–486. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Li X. Y., Gilmour P. S., Donaldson K., MacNee W.. 1996. Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro. Thorax. 51: 1216–1222. [PUBMED], [INFOTRIEVE]
  • Monn C., Becker S.. 1999. Cytotoxicity and induction of proinflammatory cytokines from human monocytes exposed to fine (PM2.5) and coarse particles (PM10–2.5) in outdoor and indoor air. Toxicol. Appl. Pharmacol.. 155: 245–252. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Oberdorster G., Sharp Z., Atudorei V., Elder A., Gelein R., Lunts A., Kreyling W., Cox C.. 2002. Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. J. Toxicol. Environ. Health A. 65: 1531–1543. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Ofosu-Appiah W., Sfeir G., Smith D., Richard T.. 1997. Neutrophil-mediated damage to vascular endothelium in the spontaneously hypertensive rat. Clin. Immunol. Immunopathol.. 83: 293–301. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Pacheco K. A., Tarkowski M., Sterritt C., Negri J., Rosenwasser L. J., Borish L.. 2001. The influence of diesel exhaust particles on mononuclear phagocytic cell-derived cytokines: IL-10, TGF-beta and IL-1 beta. Clin. Exp. Immunol.. 126: 374–383. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Pope C. A., 3rd.. 2001. Particulate air pollution, C-reactive protein, and cardiac risk. Eur. Heart J.. 22: 1149–1150. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Pope C. A., 3rd, Burnett R. T., Thun M. J., Calle E. E., Krewski D., Ito K., Thurston G. D.. 2002. Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. J. Am. Med. Assoc.. 287: 1132–1141. [CROSSREF]
  • Rosette C., Karin M.. 1996. Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors. Science. 274: 1194–1197. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Samet J. M., Silbajoris R., Huang T., Jaspers I.. 2002. Transcription factor activation following exposure of an intact lung preparation to metallic particulate matter. Environ. Health Perspect.. 110: 985–990. [PUBMED], [INFOTRIEVE]
  • Shen K., DeLano F. A., Zweifach B. W., Schmid-Schonbein G. W.. 1995. Circulating leukocyte counts, activation, and degranulation in Dahl hypertensive rats. Circ. Res.. 76: 276–283. [PUBMED], [INFOTRIEVE]
  • Snedecor G., Cochran W. G.. 1989; Statistical methods. Ames, Iowa State University Press
  • Soukup J. M., Becker S.. 2001. Human alveolar macrophage responses to air pollution particulates are associated with insoluble components of coarse material, including particulate endotoxin. Toxicol. Appl. Pharmacol.. 171: 20–26. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Takano H., Yanagisawa R., Ichinose T., Sadakane K., Yoshino S., Yoshikawa T., Morita M.. 2002. Diesel exhaust particles enhance lung injury related to bacterial endotoxin through expression of proinflammatory cytokines, chemokines, and intercellular adhesion molecule-1. Am. J. Respir. Crit. Care Med.. 165: 1329–1335. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Towbin H., Staehelin T., Gordon J.. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA. 76: 4350–4354. [PUBMED], [INFOTRIEVE]
  • Ulrich M. M., Alink G. M., Kumarathasan P., Vincent R., Boere A. J., Cassee F. R.. 2002. Health effects and time course of particulate matter on the cardiopulmonary system in rats with lung inflammation. J. Toxicol. Environ. Health A. 65: 1571–1595. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Wordley J., Walters S., Ayres J. G.. 1997. Short term variations in hospital admissions and mortality and particulate air pollution. Occup. Environ. Med.. 54: 108–116. [PUBMED], [INFOTRIEVE]
  • Yanagisawa R., Takano H., Inoue K., Ichinose T., Sadakane K., Yoshino S., Yamaki K., Kumagai Y., Uchiyama K., Yoshikawa T., Morita M.. 2003. Enhancement of acute lung injury related to bacterial endotoxin by components of diesel exhaust particles. Thorax. 58: 605–612. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Yin X. J., Schafer R., Ma J. Y., Antonini J. M., Roberts J. R., Weissman D. N., Siegel P. D., Ma J. K.. 2003. Alteration of pulmonary immunity to Listeria monocytogenes by diesel exhaust particles (DEPs). II. Effects of DEPs on T-cell-mediated immune responses in rats. Environ. Health Perspect.. 111: 524–530. [PUBMED], [INFOTRIEVE]
  • Zanobetti A., Schwartz J., Gold D.. 2000. Are there sensitive subgroups for the effects of airborne particles?. Environ. Health Perspect.. 108: 841–845. [PUBMED], [INFOTRIEVE]

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