Mesothelial cell autoantibodies upregulate transcription factors associated with fibrosis

References

• Antao VC, Larson TC, Horton DK. (2012). Libby vermiculite exposure and risk of developing asbestos-related lung and pleural diseases. Curr Opin Pulm Med 18:161–7.
   PubMed Web of Science ®Google Scholar
• Bataller R, Brenner DA. (2005). Liver fibrosis. J Clin Invest 115:209–18.
   PubMed Web of Science ®Google Scholar
• Black B, Szeinuk J, Whitehouse AC, et al. (2014). Rapid progression of pleural disease due to exposure to Libby amphibole: “Not your grandfather's asbestos related disease” . Am J Ind Med 57:1197–206.
   PubMed Web of Science ®Google Scholar
• Bosman FT, Stamenkovic I. (2003). Functional structure and composition of the extracellular matrix. J Pathol 200:423–8.
   PubMed Web of Science ®Google Scholar
• Chaudhary NI, Roth GJ, Hilberg F, et al. (2007). Inhibition of PDGF, VEGF and FGF signalling attenuates fibrosis. Eur Respir J 29:976–85.
   PubMed Web of Science ®Google Scholar
• Ferro A, Zebedeo CN, Davis C, et al. (2013). Amphibole, but not chrysotile, asbestos induces anti-nuclear autoantibodies and IL-17 in C57BL/6 mice. J Immunotoxicol 11:283–90.
   PubMed Web of Science ®Google Scholar
• Gabrielli A, Avvedimento EV, Krieg T. (2009). Scleroderma. N Engl J Med 360:1989–2003.
   PubMed Web of Science ®Google Scholar
• Ghosh AK. (2002). Factors involved in the regulation of type I collagen gene expression: implication in fibrosis. Exp Biol Med (Maywood) 227:301–14.
   PubMed Web of Science ®Google Scholar
• Ghosh AK, Bhattacharyya S, Mori Y, Varga J. (2006). Inhibition of collagen gene expression by interferon-gamma: novel role of the CCAAT/enhancer binding protein beta (C/EBPbeta). J Cell Physiol 207:251–60.
   PubMed Web of Science ®Google Scholar
• Gilmer J, Serve K, Davis C, et al. (2016). Libby amphibole induced mesothelial cell autoantibodies promote collagen deposition in mice. Am J PhysiolLung Cell Mol Physiol 310:L1071–7.
   PubMed Web of Science ®Google Scholar
• Ihn H, Sato S, Fujimoto M, et al. (2000). Characterization of autoantibodies to endothelial cells in systemic sclerosis (SSc): association with pulmonary fibrosis. Clin Exp Immunol 119:203–9.
   PubMed Web of Science ®Google Scholar
• Larson TC, Antao VC, Bove FJ. (2010). Vermiculite worker mortality: estimated effects of occupational exposure to Libby amphibole. J Occup Environ Med 52:555–60.
   PubMed Web of Science ®Google Scholar
• Larson TC, Lewin M, Gottschall EB, et al. (2012). Associations between radiographic findings and spirometry in a community exposed to Libby amphibole. Occup Environ Med 69:361–6.
   PubMed Web of Science ®Google Scholar
• Lee YH, Williams SC, Baer M, et al. (1997). The ability of C/EBP beta but not C/EBP alpha to synergize with an Sp1 protein is specified by the leucine zipper and activation domain. Mol Cell Biol 17:2038–47.
   PubMed Web of Science ®Google Scholar
• Marchand LS, St-Hilaire S, Putnam EA, et al. (2012). Mesothelial cell and anti-nuclear autoantibodies associated with pleural abnormalities in an asbestos exposed population of Libby MT. Toxicol Lett 208:168–73.
   PubMed Web of Science ®Google Scholar
• Meeker GP, Bern AM, Brownfield IK, et al. (2003). The composition and morphology of amphiboles from the Rainy Creek Complex, Near Libby, Montana. Am Mineraol 88:1955–69.
   Web of Science ®Google Scholar
• Noonan CW, Pfau JC, Larson TC, Spence MR. (2006). Nested case-control study of autoimmune disease in an asbestos-exposed population. Environ Health Persp 114:1243–7.
   PubMed Web of Science ®Google Scholar
• Peipins LA, Lewin M, Campolucci S, et al. (2003). Radiographic abnormalities and exposure to asbestos-contaminated vermiculite in the community of Libby, Montana, USA. Environ Health Persp 111:1753–9.
   PubMed Web of Science ®Google Scholar
• Pfau JC, Li S, Holland S, Sentissi JJ. (2011). Alteration of fibroblast phenotype by asbestos-induced autoantibodies. J Immunotoxicol 8:159–69.
   PubMed Web of Science ®Google Scholar
• Pfau JC, Sentissi JJ, Li S, et al. (2008). Asbestos-induced autoimmunity in C57BL/6 mice. J Immunotoxicol 5:129–37.
   PubMed Web of Science ®Google Scholar
• Pfau JC, Sentissi JJ, Weller G, Putnam EA. (2005). Assessment of autoimmune responses associated with asbestos exposure in Libby, Montana, USA. Environ Health Persp 113:25–30.
   PubMed Web of Science ®Google Scholar
• Pfau JC, Serve KM, Noonan CW. (2014). Autoimmunity and asbestos exposure. Autoimmune Dis 2014:1–11.
   Google Scholar
• Piret JP, Mottet D, Raes M, Michiels C. (2002). CoCl2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2. Annals N Y Acad Sci 973:443–7.
   PubMed Web of Science ®Google Scholar
• Roos AB, Nord M. (2012). The emerging role of C/EBPs in glucocorticoid signaling: lessons from the lung. J Endocrinol 212:291–305.
   PubMed Web of Science ®Google Scholar
• Salazar KD, Copeland CB, Wood CE, et al. (2012). Evaluation of anti-nuclear antibodies and kidney pathology in Lewis rats following exposure to Libby amphibole asbestos. J Immunotoxicol 10:329–33.
   PubMed Web of Science ®Google Scholar
• Serve KM, Black B, Szeinuk J, Pfau JC. (2013). Asbestos-associated mesothelial cell autoantibodies promote collagen deposition in vitro. Inhal Toxicol 25:774–84.
   PubMed Web of Science ®Google Scholar
• Sullivan PA. (2007). Vermiculite, respiratory disease, and asbestos exposure in Libby, Montana: update of a cohort mortality study. Environ Health Persp 115:579–85.
   PubMed Web of Science ®Google Scholar
• Tang QQ, Lane MD. (2000). Role of C/EBP homologous protein (CHOP-10) in the programmed activation of CCAAT/enhancer-binding protein-beta during adipogenesis. Proc Nat Acad Sci USA 97:12446–50.
   PubMed Web of Science ®Google Scholar
• Whitehouse AC. (2004). Asbestos-related pleural disease due to tremolite associated with progressive loss of lung function: serial observations in 123 miners, family members, and residents of Libby, Montana. Am J Ind Med 46:219–25.
   PubMed Web of Science ®Google Scholar
• Whitehouse AC, Black CB, Heppe MS, et al. (2008). Environmental exposure to Libby Asbestos and mesotheliomas. Am J Ind Med 51:877–80.
   PubMed Web of Science ®Google Scholar
• Winters CA, Hill WG, Rowse K, et al. (2012). Descriptive analysis of the respiratory health status of persons exposed to Libby amphibole asbestos. BMJ Open 2. DOI:10.1136/bmjopen-2012-001552
   PubMed Web of Science ®Google Scholar
• Wong CC, Gilkes DM, Zhang H, et al. (2011). Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Proc Nat Acad Sci USA 108:16369–74.
   PubMed Web of Science ®Google Scholar