Effects of inhaled aerosolized carfentanil on real-time physiological responses in mice: a preliminary evaluation of naloxone

References

• Bilbey DLJ, Salem H, Grossman MH. (1960). The anatomical basis of the straub phenomenon. Br J Pharmacol Chemother 15:540–3.
   PubMed Web of Science ®Google Scholar
• Bouillon T, Bruhn J, Roepcke H, Hoeft A. (2003). Opioid-induced respiratory depression is associated with increased tidal volume variability. Eur J Anaesthesiol 20:127–33.
   PubMed Web of Science ®Google Scholar
• Cochran G, Gordon AJ, Field C, et al. (2016). Developing a framework of care for opioid medication misuse in community pharmacy. Res Social Adm Pharm 12:293–301.
   PubMed Web of Science ®Google Scholar
• Compton WM, Boyle M, Wargo E. (2015). Prescription opioid abuse: problems and responses. Prev Med 80:5–9.
   PubMed Web of Science ®Google Scholar
• Dahan A, Aarts L, Smith TW. (2010). Incidence, reversal, and prevention of opioid-induced respiratory depression. Anesthesiology 112:226–38.
   PubMed Web of Science ®Google Scholar
• Feng Y, He X, Yang Y, et al. (2012). Current research on opioid receptor function. Curr Drug Targets 13:230–46.
   PubMed Web of Science ®Google Scholar
• Freye E, Schnitzler M, Schenk G. (1991). Opioid-induced respiratory depression and analgesia may be mediated by different subreceptors. Pharm Res 8:196–9.
   PubMed Web of Science ®Google Scholar
• George AV, Lu JJ, Pisano MV, et al. (2010). Carfentanil – an ultra potent opioid. Am J Emerg Med 28:530–2.
   PubMed Web of Science ®Google Scholar
• Glasser SB, Baker P. 2002. Russia Confirms Suspicions About Gas Used in Raid; Potent Anesthetic Pumped Into Theater; 2 More Hostages Die From Drug's Effects. The Washington Post Sect. Section|:Start Page| (col. Column)|.
   Google Scholar
• Haigh JC, Gates CC. (1995). Capture of wood bison (Bison bison athabascae) using carfentanil-based mixtures. J Wildl Dis 31:37–42.
   PubMed Web of Science ®Google Scholar
• Haigh JC, Lee LJ, Schweinsburg RE. (1983). Immobilization of polar bears with carfentanil. J Wildl Dis 19:140–4.
   PubMed Web of Science ®Google Scholar
• Halverson TG, Teare JA. (1989). Carfentanil and overwinter survival in bison: the alternative hypothesis. J Wildl Dis 25:448–54.
   PubMed Web of Science ®Google Scholar
• Hardy JD. (1973). Posterior hypothalamus and the regulation of body temperature. Fed Proc 32:1564–71.
   PubMedGoogle Scholar
• Heard DJ, Kollias GV, Buss D, et al. (1990). Comparative cardiovascular effects of intravenous etorphine and carfentanil in domestic goats. J Zoo Wildl Med 21:166–70.
   Web of Science ®Google Scholar
• Heard DJ, Nichols WW, Buss D, Kollias GV. (1996). Comparative cardiopulmonary effects of intramuscularly administered etorphine and carfentanil in goats. Am J Vet Res 57:87–96.
   PubMed Web of Science ®Google Scholar
• Heinekamp W. (1922). The mechanism of the Straub biologic test for morphine. J Pharmacol Exp Ther 20:107–13.
   Google Scholar
• Hurle MA, Mediavilla A, Florez J. (1985). Differential respiratory patterns induced by opioids applied to the ventral medullary and dorsal pontine surfaces of cats. Neuropharmacology 24:597–606.
   PubMed Web of Science ®Google Scholar
• Jarzyna D, Jungquist CR, Pasero C, et al. (2011). American Society for Pain Management Nursing guidelines on monitoring for opioid-induced sedation and respiratory depression. Pain Manag Nurs 12:118–45 e110.
   PubMed Web of Science ®Google Scholar
• Jungquist CR, Correll DJ, Fleisher LA, et al. (2016). Avoiding adverse events secondary to opioid-induced respiratory depression: implications for nurse executives and patient safety. J Nurs Adm 46:87–94.
   PubMed Web of Science ®Google Scholar
• Jungquist CR, Karan S, Perlis ML. (2011). Risk factors for opioid-induced excessive respiratory depression. Pain Manag Nurs 12:180–7.
   PubMed Web of Science ®Google Scholar
• Kenakin T. (2014). What is pharmacological 'affinity'? Relevance to biased agonism and antagonism. Trends Pharmacol Sci 35:434–41.
   PubMed Web of Science ®Google Scholar
• Kolodny A, Courtwright DT, Hwang CS, et al. (2015). The prescription opioid and heroin crisis: a public health approach to an epidemic of addiction. Annu Rev Public Health 36:559–74.
   PubMed Web of Science ®Google Scholar
• Krechetnikov A. (2012). “Moscow theatre siege: questions remain unanswered.” Available from: http://www.bbc.com/news/world-europe-20067384. [Last accessed: 21 Dec 2016].
   Google Scholar
• Lalley PM. (2008). Opioidergic and dopaminergic modulation of respiration. Respir Physiol Neurobiol 164:160–7.
   PubMed Web of Science ®Google Scholar
• Lalley PM, Pilowsky PM, Forster HV, Zuperku EJ. (2014a). CrossTalk opposing view: the pre‐Bötzinger complex is not essential for respiratory depression following systemic administration of opioid analgesics. J Physiol 592:1163–6.
   PubMed Web of Science ®Google Scholar
• Lalley PM, Pilowsky PM, Forster HV, Zuperku EJ. (2014b). Rebuttal from Peter M. Lalley, Paul M. Pilowsky, Hubert V. Forster and Edward J. Zuperku. J Physiol 592:1169.
   PubMed Web of Science ®Google Scholar
• Lee LA, Caplan RA, Stephens LS, et al. (2015). Postoperative opioid-induced respiratory depression: a closed claims analysis. Anesthesiology 122:659–65.
   PubMed Web of Science ®Google Scholar
• Leimdorfer A. (1948). An electroencephalographic analysis of the action of amidone, morphine and strychnine on the central nervous system. Arch Int Pharmacodyn Ther 76:153–62.
   PubMedGoogle Scholar
• Lewanowitsch T, Irvine RJ. (2002). Naloxone methiodide reverses opioid-induced respiratory depression and analgesia without withdrawal. Eur J Pharmacol 445:61–7.
   PubMed Web of Science ®Google Scholar
• Lichtman AH, Meng Y, Martin BR. (1996). Inhalation exposure to volatilized opioids produces antinociception in mice. J Pharmacol Exp Ther 279:69–76.
   PubMed Web of Science ®Google Scholar
• Ly HG, Dupont P, Geeraerts B, et al. (2013). Lack of endogenous opioid release during sustained visceral pain: a [11C]carfentanil PET study. Pain 154:2072–7.
   PubMed Web of Science ®Google Scholar
• Manral L, Muniappan N, Gupta PK, et al. (2009). Effect of exposure to fentanyl aerosol in mice on breathing pattern and respiratory variables. Drug Chem Toxicol 32:108–13.
   PubMed Web of Science ®Google Scholar
• McEvoy G, ed. (2012). AHFS drug information 2012. Bethesda, Md.: American Society of Health-System Pharmacists.
   Google Scholar
• Miller MW, Wild MA, Lance WR. (1996). Efficacy and safety of naltrexone hydrochloride for antagonizing carfentanil citrate immobilization in captive Rocky Mountain elk (Cervus elaphus nelsoni). J Wildl Dis 32:234–9.
   PubMed Web of Science ®Google Scholar
• Montandon G, Horner R. (2014a). CrossTalk proposal: the preBötzinger complex is essential for the respiratory depression following systemic administration of opioid analgesics. J Physiol 592:1159–62.
   PubMed Web of Science ®Google Scholar
• Montandon G, Horner R. (2014b). Rebuttal from Gaspard Montandon and Richard Horner. J Physiol 592:1167.
   PubMed Web of Science ®Google Scholar
• Moresco A, Larsen RS, Sleeman JM, et al. (2001). Use of naloxone to reverse carfentanil citrate-induced hypoxemia and cardiopulmonary depression in Rocky Mountain wapiti (Cervus elaphus nelsoni). J Zoo Wildl Med 32:81–9.
   PubMed Web of Science ®Google Scholar
• Muhuri PK, Gfroerer JC, Davies MC. (2013). Associations of nonmedical pain reliever use and initiation of heroin use in the United States. CBHSQ Data Rev 1–17.
   Google Scholar
• Mutlow A, Isaza R, Carpenter JW, et al. (2004). Pharmacokinetics of carfentanil and naltrexone in domestic goats (Capra hircus). J Zoo Wildl Med 35:489–96.
   PubMed Web of Science ®Google Scholar
• Olofsen E, van Dorp E, Teppema L, et al. (2010). Naloxone reversal of morphine- and morphine-6-glucuronide-induced respiratory depression in healthy volunteers: a mechanism-based pharmacokinetic–pharmacodynamic modeling study. Anesthesiology 112:1417–27.
   PubMed Web of Science ®Google Scholar
• Riches JR, Read RW, Black RM, et al. (2012). Analysis of clothing and urine from Moscow theatre siege casualties reveals carfentanil and remifentanil use. J Anal Toxicol 36:647–56.
   PubMed Web of Science ®Google Scholar
• Rodbard S. (1948). Body temperature, blood pressure, and hypothalamus. Science 108:413–5.
   PubMed Web of Science ®Google Scholar
• Stanley T. (2003). Human immobilization: is the experience in Moscow just the beginning? Eur J Anaesthesiol 20:427–8.
   PubMed Web of Science ®Google Scholar
• Straub W. (1911). Eine empfindliche biologische Reaktion auf Morphin. Dtsch Med Wochenschr 37:1462–8.
   Google Scholar
• Tefera L, Lehrman WG, Goldstein EG, Agrawal S. (2016). A special contribution from the centers for medicare and medicaid services: valuing patient experience while addressing the prescription opioid epidemic. Ann Emerg Med. doi: 10.1016/j.annemergmed.2016.06.047
   PubMed Web of Science ®Google Scholar
• Titeler M, Lyon RA, Kuhar MJ, et al. (1989). Mu opiate receptors are selectively labelled by [3H]carfentanil in human and rat brain. Eur J Pharmacol 167:221–8.
   PubMed Web of Science ®Google Scholar
• Wittert G, Hope P, Pyle D. (1996). Tissue distribution of opioid receptor gene expression in the rat. Biochem Biophys Res Commun 218:877–81.
   PubMed Web of Science ®Google Scholar
• Yeadon M, Kitchen I. (1990). Multiple opioid receptors mediate the respiratory depressant effects of fentanyl-like drugs in the rat. Gen Pharmacol Vascul Syst 21:655–64.
   PubMedGoogle Scholar