Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 29, 2017 - Issue 12-14
275
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Comparative inhalation toxicity of ethyltoluene isomers in rats and mice

ORCID Icon, , , &
Pages 577-585 | Received 07 Sep 2017, Accepted 16 Jan 2018, Published online: 29 Jan 2018

References

  • Axelson O, Hane M, Hogstedt C. (1976). A case-reference study on neuropsychiatric disorders among workers exposed to solvents. Scand J Work Environ Health 2:14–20.
  • Baker EL, Smith TJ, Landrigan PJ. (1985). The neurotoxicity of industrial solvents: a review of the literature. Am J Ind Med 8:207–17.
  • Brautbar N, Williams J. (2002). Industrial solvents and liver toxicity: risk assessment, risk factors and mechanisms. Int J Hyg Environ Health 205:479–91.
  • Chemical Effects in Biological Systems (CEBS). Accession Number: 002-00052-0001-000-0. Research Triangle Park, NC (USA): National Toxicology Program (NTP). https://doi.org/10.22427/NTP-DATA-1
  • Evans EB, Balster RL. (1991). CNS depressant effects of volatile organic solvents. Neurosci Behav Rev 15:233–41.
  • Forziati AF, Rossini FD. (1947). Alkylbenzenes in the C9 fraction from seven representative crude petroleums. J Res 39:425–33.
  • Glowa JR. (1990). Behavioral toxicology of solvents. Drug Dev Res 20:411–82.
  • Grasso P, Sharratt M, Davies DM, Irvine D. (1984). Neurophysiological and psychological disorders and occupational exposure to organic solvents. Food Chem Toxicol 22:819–52.
  • Grawewicz S, Wiaderna D. (2001). Behavioral effects following subacute inhalation exposure to m-xylene or trimethylbenzene in the rat: a comparative study. Neurotoxicology 22:79–89.
  • Harley RA, Kean JA. (2004). Chemical composition of vehicle-related volatile organic compound emission in central California. Berkeley, California: Department of Civil and Environmental Engineering University of California.
  • Kassotis CD, Klemp KC, Vu DC, et al. (2015). Endocrine-disrupting activity of hydraulic fracturing chemicals and adverse health outcomes after prenatal exposure in male mice. Endocrinology 156:1–16.
  • Korsak Z, Rydzynski K. (1996). Neurotoxic effects of acute and subchronic inhalation exposure to trimethylbenzene isomers (pseudocumene, mesitylene, hemimellitene) in rats. Int J Occup Med Environ Health 9:341–9.
  • National Research Council. (1996). Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academies Press.
  • National Toxicology Program (NTP). (2009). Toxicology and carcinogenesis studies of cumene (CAS No. 98-82-8) in F344/N rats and B6C3F1 mice (Inhalation Studies). Technical Report Series No. 542. NIH Publication No. 09-5885. US Department of Health and Human Services, Public Health Service, National Institutes of Health, Research Triangle Park, NC
  • National Toxicology Program (NTP). (1999). Toxicology and carcinogenesis studies of ethylbenzene (CAS No.100-41-4) in F344/N rats and B6C3F1 mice (Inhalation Studies). Technical Report Series No. 466. NIH Publication No. 99-3956. US Department of Health and Human Services, Public Health Service, National Institutes of Health, Research Triangle Park, NC
  • Reed CJ. (1993). Drug metabolism in the nasal cavity: relevance to toxicology. Drug Metab Rev 25:173–205.
  • Renne R, Brix A, Harkema J, et al. (2009). Proliferative and nonproliferative lesions of the rat and mouse respiratory tract. Toxicol Pathol 37:5S–73S.
  • Swiercz R, Rydzynski K, Jajte J, et al. (2000). Studies on dermal, ocular and respiratory effects of 4-ethyltoluene in experimental animals. Int J Occup Med Environ Health 13:307–15.
  • US Environmental Protection Agency. (2010). Hydrocarbon Composition of Gasoline Vapor Emissions from Enclosed Fuel Tanks. EPA publication-420-D-10-001.
  • US Environmental Protection Agency (2016). Chemical Data Reporting for Benzene, ethylmethyl-, CAS number 25550-14-5.
  • Zhang M, Wang Y, Yang D, et al. (2015). Roles of oxidative damage and mitochondria-mediated apoptosis in ethylbenzene-induced hepatotoxic effects in rat. Inhal Toxicol. 27:64–73.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.