A review of pulmonary toxicity studies of nanocellulose

References

• Adamis Z, Tátrai E, Honma K, Ungváry G. 1997. In vitro and in vivo assessment of the pulmonary toxicity of cellulose. J Appl Toxicol. 17(2):137–141.
   PubMed Web of Science ®Google Scholar
• Bar A, Van Ommen B, Timonen M. 1995. Metabolic disposition in rats of regular and enzymatically depolymerized sodium carboxymethylcellulose. Food Chem Toxicol. 33(11):901–907.
   PubMed Web of Science ®Google Scholar
• Catalán J, Rydman E, Aimonen K, Hannukainen KS, Suhonen S, Vanhala E, Moreno C, Meyer V, Perez DD, Sneck A, Forsström U, et al. 2017. Genotoxic and inflammatory effects of nanofibrillated cellulose in murine lungs. Mutagenesis. 32(1):23–31.
   PubMed Web of Science ®Google Scholar
• Chen M, Sun Y, Liang J, Zeng G, Li Z, Tang L, Zhu Y, Jiang D, Song B. 2019. Understanding the influence of carbon nanomaterials on microbial communities. Environ Int. 126:690–698.
   PubMed Web of Science ®Google Scholar
• Clift MJD, Foster EJ, Vanhecke D, Studer D, Wick P, Gehr P, Rothen-Rutishauser B, Weder C. 2011. Investigating the interaction of cellulose nanofibers derived from cotton with a sophisticated 3D human lung cell coculture. Biomacromolecules. 12(10):3666–3673.
   PubMed Web of Science ®Google Scholar
• Cullen RT, Searl A, Miller BG, Davis JM, Jones AD. 2000. Pulmonary and intraperitoneal inflammation induced by cellulose fibres. J Appl Toxicol. 20(1):49–60.
   PubMed Web of Science ®Google Scholar
• Davis J. 1993. The need for standardising testing procedure for all products capable of liberating respirable fibers: the example of materials based on cellulose. Br J Ind Med. 50(2):187–190.
   Google Scholar
• de Lima R, Oliveira FL, Rodrigues MC, Abreu BM, Yamawaki PC, Vieira IJ, Teixeira EM, Corrêa AC, Caparelli MLH, Fernandes FL. 2012. Evaluation of the genotoxicity of cellulose nanofibers. Int J Nanomed. 7:3555–3565.
   PubMed Web of Science ®Google Scholar
• Deng X, Jia G, Wang H, Sun H, Wang X, Yang S, Wang T, Liu Y. 2007. Translocation and fate of multi-walled carbon nanotubes in vivo. Carbon. 45(7):1419–1424.
   Web of Science ®Google Scholar
• Despres HW, Sabra A, Anderson P, Hemraz UD, Boluk Y, Sunasee R, Ckless K. 2019. Mechanisms of the immune response cause by cationic and anionic surface functionalized cellulose nanocrystals using cell-based assays. Toxicol in Vitro. 55:124–133.
   PubMed Web of Science ®Google Scholar
• Dong J, Ma Q. 2015. Advances in mechanisms and signaling pathways of carbon nanotube toxicity. Nanotoxicology. 9(5):658–676.
   PubMed Web of Science ®Google Scholar
• Eichhorn SJ, Dufresne A, Aranguren M, Marcovich NE, Capadona JR, Rowan SJ, Weder C, Thielemans W, Roman M, Renneckar S, et al. 2010. Review: current international research into cellulose nanofibres and nanocomposites. J Mater Sci. 45(1):1–33.
   Web of Science ®Google Scholar
• Elder R. 1986. Final report on the safety assessment of hydroxyethylcellulose, hydroxypropylcellulose, methylcellulose, hydroxypropyl methylcellulose and cellulose gum. J Am Col Toxicol. 5:1–59.
   Google Scholar
• Ellakkani MA, Alarie Y, Weyel D, Karol MH. 1987. Chronic pulmonary effects in guinea pigs from prolonged inhalation of cotton dust. Toxicol Appl Pharmacol. 88(3):354–369.
   PubMed Web of Science ®Google Scholar
• Ellakkani MA, Alarie YC, Weyel DA, Mazumdar S, Karol MH. 1984. Pulmonary reactions to inhaled cotton dust: an animal model for byssinosis. Toxicol Appl Pharmacol. 74(2):267–284.
   PubMed Web of Science ®Google Scholar
• Ema M, Imamura T, Suzuki H, Kobayashi N, Naya M, Nakanishi J. 2012. Evaluation of genotoxicity of multi-walled carbon nanotubes in a battery of in vitro and in vivo assays. Regul Toxicol Pharmacol. 63(2):188–195.
   PubMed Web of Science ®Google Scholar
• Endes C, Mueller S, Kinnear C, Vanhecke D, Foster EJ, Petri-Fink A, Weder C, Clift MJ, Rothen-Rutishauser B. 2015. Fate of cellulose nanocrystal aerosols deposited on the lung cell surface in vitro. Biomacromolecules. 16(4):1267–1275.
   PubMed Web of Science ®Google Scholar
• Farcas MT, Kisin ER, Menas AL, Gutkin DW, Star A, Reiner RS, Yanamala N, Savolainen K, Shvedova AA. 2016. Pulmonary exposure to cellulose nanocrystals caused deleterious effects to reproductive system in male mice. J Toxicol Environ Health Part A. 79(21):984–997.
   PubMed Web of Science ®Google Scholar
• Food and Drug Administration 1973. Select Committee on GRAS Substances. [accessed 13 May 2019]. https://www.accessdata.fda.gov/scripts/fdcc/?set=SCOGS&sort=Sortsubstance&order=ASC&startrow=1&type=basic&search=cellulose.
   Google Scholar
• Fujita K, Fukuda M, Endoh S, Maru J, Kato H, Nakamura A, Shinohara N, Uchino K, Honda K. 2016. Pulmonary and pleural inflammation after intratracheal instillation of short single-walled and multi-walled carbon nanotubes. Toxicol Lett. 257:23–37.
   PubMed Web of Science ®Google Scholar
• Glegg RE, Kertesz ZI. 1957. Effect of gamma‐radiation on cellulose. J Polym Sci. 26(114):289–297.
   Google Scholar
• Hadrup N, Knudsen KB, Berthing T, Wolff H, Bengtson S, Kofoed C, Espersen R, Højgaard C, Winther JR, Willemoës M, et al. 2019. Pulmonary effects of nanofibrillated celluloses in mice suggest that carboxylation lowers the inflammatory and acute phase responses. Environ Toxicol Pharmacol. 66:116–125.
   PubMed Web of Science ®Google Scholar
• Ilves M, Vilske S, Aimonen K, Lindberg HK, Pesonen S, Wedin I, Nuopponen M, Vanhala E, Højgaard C, Winther JR, et al. 2018. Nanofibrillated cellulose causes acute pulmonary inflammation that subsides within a month. Nanotoxicology. 12(7):729–746.
   PubMed Web of Science ®Google Scholar
• Jelinková M, Briestenský J, Santar I, Ríhová B. 2002. In vitro and in vivo immunomodulatory effects of microdispersed oxidized cellulose. Int Immunopharmacol. 2(10):1429–1441.
   PubMed Web of Science ®Google Scholar
• Jimenez AS, Jaramillo F, Hemraz UD, Boluk Y, Ckless K, Sunasee R. 2017. Effect of surface organic coatings of cellulose nanocrystals on the viability of mammalian cell lines. Nanotechnol Sci Appl. 10:123–136.
   PubMed Web of Science ®Google Scholar
• Kimura T, Sudo K, Kanzaki Y, Miki K, Takeichi Y, Kurosaki Y, Nakayama T. 1994. Drug absorption from large intestine: physicochemical factors governing drug absorption. Biol Pharm Bull. 17(2):327–333.
   PubMed Web of Science ®Google Scholar
• Kobayashi N, Izumi H, Morimoto Y. 2017. Review of toxicity studies of carbon nanotubes. J Occup Health. 59(5):394–407.
   PubMed Web of Science ®Google Scholar
• Lopes VR, Sanchez-Martinez C, Strømme M, Ferraz N. 2017. In vitro biological responses to nanofibrillated cellulose by human dermal, lung and immune cells: surface chemistry aspect. Part Fibre Toxicol. 14(1):1.
   PubMedGoogle Scholar
• Mahmoud KA, Mena JA, Male KB, Hrapovic S, Kamen A, Luong JH. 2010. Effect of surface charge on the cellular uptake and cytotoxicity of fluorescent labeled cellulose nanocrystals. ACS Appl Mater Interf. 2(10):2924–2932.
   PubMed Web of Science ®Google Scholar
• Menas AL, Yanamala N, Farcas MT, Russo M, Friend S, Fournier PM, Star A, Iavicoli I, Shurin GV, Vogel UB, et al. 2017. Fibrillar vs crystalline nanocellulose pulmonary epithelial cell responses: cytotoxicity or inflammation?. Chemosphere. 171:671–680.
   PubMed Web of Science ®Google Scholar
• Milton DK, Godleski JJ, Feldman HA, Greaves IA. 1990. Toxicity of intratracheally instilled cotton dust, cellulose, and endotoxin. Am Rev Respir Dis. 142(1):184–192.
   PubMedGoogle Scholar
• Moon RJ, Martini A, Nairn J, Simonsen J, Young-Blood J. 2011. Cellulose nanomaterials review: structure, properties and nanocomposites. Chem Soc Rev. 40(7):3941–3994.
   PubMed Web of Science ®Google Scholar
• Morgan DL. 2006. NTP Toxicity Study Report on the atmospheric characterization, particle size, chemical composition, and workplace exposure assessment of cellulose insulation (celluloseins). Toxic Rep Ser. 74:1–62.
   Google Scholar
• Morgan DL, Su YF, Dill JA, Turnier JC, Westerberg RB, Smith CS. 2004. Chemical and physical characteristics of cellulose insulation particulates, and evaluation of potential acute pulmonary toxicity. Am J Ind Med. 46(6):554–569.
   PubMed Web of Science ®Google Scholar
• Muhle H, Ernstb H, Bellmann B. 1997. Investigation of the durability of cellulose fibres in rat lungs. Ann Occup Hyg. 41:184–188.
   Google Scholar
• Muller J, Delos M, Panin N, Rabolli V, Huaux F, Lison D. 2009. Absence of carcinogenic response to multiwall carbon nanotubes in a 2-year bioassay in the peritoneal cavity of the rat. Toxicol Sci. 110(2):442–448.
   PubMed Web of Science ®Google Scholar
• Munk M, Camargo LS, Quintão CC, Silva SR, Souza ED, Raposo NR, Marconcini JM, Jorio A, Ladeira LO, Brandão HM. 2016. Biocompatibility assessment of fibrous nanomaterials in mammalian embryos. Nanomedicine. 12(5):1151–1159.
   PubMed Web of Science ®Google Scholar
• Nagato LK, Lourenço MG, Cadete RA, Leite-Júnior JH, Koatz VL, Rocco PR, Faffe DS, Zin WA. 2008. Microcrystalline cellulose induces time-dependent lung functional and inflammatory changes. Respir Physiol Neurobiol. 164(3):331–337.
   PubMed Web of Science ®Google Scholar
• Noguchi Y, Homma I, Matsubara Y. 2017. Complete nanofibrillation of cellulose prepared by phosphorylation. Cellulose. 24(3):1295–1305.
   Web of Science ®Google Scholar
• Park EJ, Khaliullin TO, Shurin MR, Kisin ER, Yanamala N, Fadeel B, Chang J, Shvedova AA. 2018. Fibrous nanocellulose, crystalline nanocellulose, carbon nanotubes, and crocidolite asbestos elicit disparate immune responses upon pharyngeal aspiration in mice. J Immunotoxicol. 15(1):12–23.
   PubMed Web of Science ®Google Scholar
• Pinto FCM, De-Oliveira A, De-Carvalho RR, Gomes-Carneiro MR, Coelho DR, Lima SVC, Paumgartten FJR, Aguiar J. 2016. Acute toxicity, cytotoxicity, genotoxicity and antigenotoxic effects of a cellulosic exopolysaccharide obtained from sugarcane molasses. Carbohydr Polym. 137:556–560.
   PubMed Web of Science ®Google Scholar
• Pitkanen M, Kangas H, Laitinen O, Sneck A, Lahtinen P, Peresin MS, Niinimäki J. 2014. Characteristics and safety of nano-sized cellulose fibrils. Cellulose. 21(6):3871–3886.
   Web of Science ®Google Scholar
• Rajinipriya M, Nagalakshmaiah M, Robert M, Elkoun S. 2018. Importance of agricultural and industrial waste in the field of nanocellulose and recent industrial developments of wood based nanocellulose: a review. ACS Sustainable Chem Eng. 6(3):2807–2828.
   Web of Science ®Google Scholar
• Rol F, Belgacem MN, Gandini A, Bras J. 2019. Recent advances in surface-modified cellulose nanofibrils. Prog Polym Sci. 88:241–264.
   Web of Science ®Google Scholar
• Shatkin JA, Oberdörster G. 2016. Comment on Shvedova et al. (2016), “gender differences in murine pulmonary responses elicited by cellulose nanocrystals". Part Fibre Toxicol. 13(1):59.
   PubMedGoogle Scholar
• Shvedova AA, Kisin ER, Yanamala N, Farcas MT, Menas AL, Williams A, Fournier PM, Reynolds JS, Gutkin DW, Star A, et al. 2016. Gender differences in murine pulmonary responses elicited by cellulose nanocrystals. Part Fibre Toxicol. 13(1):28.
   PubMedGoogle Scholar
• Silva-Carvalho R, Silva JP, Ferreirinha P, Leitão AF, Andrade FK, Gil da CRM, Cristelo C, Rosa MF, Vilanova M, Gama FM. 2019. Inhalation of bacterial cellulose nanofibrils triggers an inflammatory response and changes lung tissue morphology of mice. Toxicol Res. 35(1):45–63.
   PubMed Web of Science ®Google Scholar
• Stefaniak AB, Seehra MS, Fix NR, Leonard SS. 2014. Lung biodurability and free radical production of cellulose nanomaterials. Inhal Toxicol. 26(12):733–749.
   PubMed Web of Science ®Google Scholar
• Takagi A, Hirose A, Futakuchi M, Tsuda H, Kanno J. 2012. Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice. Cancer Sci. 103(8):1440–1444.
   PubMed Web of Science ®Google Scholar
• Tátrai E, Brozik M, Adamis Z, Merétey K, Ungváry G. 1996. In vivo pulmonary toxicity of cellulose in rats. J Appl Toxicol. 16(2):129–135.
   PubMed Web of Science ®Google Scholar
• Tayeb AH, Amini E, Ghasemi S, Tajvidi M. 2018. Cellulose nanomaterials—binding properties and applications: a review. Molecules. 23(10):2684.
   PubMed Web of Science ®Google Scholar
• Toyokuni S. 2013. Genotoxicity and carcinogenicity risk of carbon nanotubes. Adv Drug Deliv Rev. 65(15):2098–2110.
   PubMed Web of Science ®Google Scholar
• van der Laan JW, DeGeorge J Jr. 2013. Global approach in safety testing: ICH guidelines explained. New York (NY): Springer. ISBN 978-1-4614-5950-7.
   Google Scholar
• Ventura C, Lourenço AF, Sousa-Uva A, Ferreira PJT, Silva MJ. 2018. Evaluating the genotoxicity of cellulose nanofibrils in a co-culture of human lung epithelial cells and monocyte-derived macrophages. Toxicol Lett. 291:178–183.
   Web of Science ®Google Scholar
• Wang X, Chang CH, Jiang J, Liu Q, Liao YP, Lu J, Li L, Liu X, Kim J, Ahmed A, et al. 2019. The crystallinity and aspect ratio of cellulose nanomaterials determine their pro-inflammatory and immune adjuvant effects in vitro and in vivo. Small. 15(42):e1901642.
   PubMed Web of Science ®Google Scholar
• Yanamala N, Farcas MT, Hatfield MK, Kisin ER, Kagan VE, Geraci CL, Shvedova AA. 2014. In Vivo evaluation of the pulmonary toxicity of cellulose nanocrystals: a renewable and sustainable nanomaterial of the future. ACS Sustain Chem Eng. 2(7):1691–1698.
   PubMed Web of Science ®Google Scholar
• Yanamala N, Kisin ER, Menas AL, Farcas MT, Khaliullin TO, Vogel UB, Shurin GV, Schwegler-Berry D, Fournier PM, Star A, et al. 2016. In vitro toxicity evaluation of lignin-(un)coated cellulose based nanomaterials on human A549 and THP-1 cells. Biomacromolecules. 17(11):3464–3473.
   PubMed Web of Science ®Google Scholar