Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 10, 1998 - Issue 5
19
Views
21
CrossRef citations to date
0
Altmetric
Research Article

COMPUTATIONAL FLUID DYNAMICS SIMULATIONS OF INSPIRATORY AIRFLOW IN THE HUMAN NOSE AND NASOPHARYNX

Pages 473-502 | Published online: 01 Oct 2008

References

  • Andersen, I., and Proctor, D. F. 1982. The fate and effects of inhaled materials. In The nose, upper airway physiology and the atmospheric environment, eds. D. F. Proctor and I. Andersen, pp. 423-455. New York: Elsevier Biomedical Press.
  • Bridger, G. P., and Proctor, D. F. 1970. Maximum nasal inspiratory flow and nasal resistance. Ann. Otol. Rhinol. LaryngoL 79:481–488.
  • Brin, L., Huband, J., Miller, J., Potter, L. K., Price, M., Kimbell, J. S., and Kepler, G. M. 1997. Shape-based mathematical modeling of the human nasal passages. Proceedings, NCSU 1996 Industrial Mathematics Modeling Workshop For Graduate Students, CRSC-TR97-8 37–66.
  • Cole, P. 1982. Upper respiratory airflow. In The nose, upper airway physiology and the atmospheric environment, eds. D. F. Proctor and I. Andersen, pp. 163-183. New York: Elsevier Biomedical Press.
  • Cole, P. 1993. The respiratory role of the upper airways. St. Louis, MO: Mosby Year Book.
  • Elad, D., Liebenthal, R., Wenig, B. L., and Einav, S. 1993. Analysis of airflow patterns in the human nose. Med. Biol. Eng. Comput. 31:585–592.
  • Fluid Dynamics International. 1991. FIDAP. Fluid dynamics analysis package: Theory manual. Evanston, IL: Fluid Dynamics International (now Fluent Inc., Lebanon, NH).
  • Fluid Dynamics International. 1996. FIDAP. Fluid dynamics analysis package: User's manual. Evanston, IL: Fluid Dynamics International (now Fluent Inc., Lebanon, NH).
  • Frederick, C. B., Morris, J. B., Kimbell, J. S., Morgan, K. T., and Scherer, P. S. 1994. Comparison of four biologically based dosimetry models for the deposition of rapidly metabolized vapors in the rodent nasal cavity. Inhal. Toxicol. 6(suppl.):135–157.
  • Girardin, M., Bilgen, E., and Arbour, P. 1983. Experimental studies of velocity fields in a human nasal fossa by laser anemometry. Ann. Otol. Rhinol. LaryngoL 92:231–236.
  • Godo, M. N., Morgan, K. T., Richardson, R. B., and Kimbell, J. S. 1995. Reconstruction of complex passageways for simulations of transport phenomena: Development of a graphical user interface for biological applications. Comp. Meth. Prog. Biomed. 47:97–112.
  • Guilmette, R. A., Cheng, Y. S., Yeh, H. C., and Swift, D. L. 1994. Deposition of O.005-12 pm monodisperse particles in a computer-milled MR-imaging based nasal airway replica. Inhal. Toxicol. 6\(suppl. 1):395–399.
  • Hahn, I., Scherer, P. W., and Mozel, M. M. 1993. Velocity profiles measured for airflow through a large-scale model of the human nasal cavity.]. Appl. PhysioL 75:2273–2287.
  • Haight, S. J., and Cole, P. 1983. Site and function of the nasal valve. Laryngoscope. 93:49-55. Hirschberg, A., Roithmann, R., Parikh, S., Miljeteig, H., and Cole, P. 1995. The airflow resistance profile of healthy nasal cavities. Rhinology33:10–13.
  • Hornung, D. E., Leopold, D. A., Youngentob, S. L., Sheehe, P. R., Gagne, G. M., Thomas, F. D., and Mozell, M. M. 1987. Airflow patterns in a human nasal model. Arch. OtolaryngoL Head Neck Surg. 113:169–172.
  • International Commission on Radiological Protection. 1975. Report on the task group on Reference Man. Oxford: Pergamon Press.
  • Keyhani, K., Scherer, P. W., and Mozell, M. M. 1995. Numerical simulation of airflow in the human nasal cavity.]. Biomech. Eng. 117:429–441.
  • Kimbell, J. S., Gross, E. A., Joyner, D. R., Godo, M. N., and Morgan, K. T. 1993. Application of com-putational fluid dynamics to regional dosimetry of inhaled chemicals in the upper respiratory tract of the rat. Toxicol. Appl. PharmacoL 121:253–263.
  • Lang, J. 1989. Clinical anatomy of the nose, nasal cavity and paranasal sinuses. New York: Thieme Medical.
  • Lanza, D. C., and Clerico, D. M. 1995. Anatomy of the human nasal passages. In Handbook of olfac-tion and gustation, ed. R. L. Doty, pp. 53-73. New York: Marcel Dekker.
  • Masing, H. 1967. Expermentelle untersuchungen Ober den strömungsverlauf im nasenmodell. Arch. Klin. Exp. Ohren. Nasen Kehlkopfheilk189:371–381.
  • Miller, F. J., ed. 1995. Nasal toxicity and dosimetry of inhaled xenobiotics. Washington, DC: Taylor & Francis.
  • Morgan, K. T., and Monticello, T. M. 1990. Airflow, gas deposition, and lesion distribution in the nasal passages. Environ. Health Perspect. 85:209–218.
  • Morgan, K. T., Kimbell, J. S., Monticello, T. M., Patra, A. L., and Fleishman, A. 1991. Studies of inspi-ratory airflow patterns in the nasal passages of the F344 rat and rhesus monkey using nasal molds: Relevance to formaldehydetoxicity. Toxicol. Appl. PharmacoL 110:223–240.
  • Negus, V. 1958. The comparative anatomy and physiology of the nose and paranasal sinuses. London: Livingstone.
  • Olsen, J. H., and Asnaes, S. 1985. Formaldehyde and the risk of squamous cell carcinoma of the sinonasal cavities. Br.]. Ind. Hyg. 43:769–774.
  • Pedley, T. J., Schroter, R. C., and Sudlow, M. F. 1977. Gas flow and mixing in airways. In Bioengi-neering aspects of the lung, ed. J. B. West, pp. 229-233. New York: Marcel Dekker.
  • Proctor, D. F. 1982. The upper airway. In The nose, upper airway physiology and the atmospheric environment, eds. D. F. Proctor and I. Andersen, pp. 23-43. New York: Elsevier Biomedical Press.
  • Proetz, A. W. 1951. Air currents in the upper respiratory tract and their clinical importance. Ann. OtoL Rhinol. LaryngoL 60:439–467.
  • Roush, G. C., Walrath, J., Stayner, L. T., Kaplan, S. A., Flannery, J. T., and Blair, A. 1987. Naso-pharyngeal cancer, sinonasal cancer, and occupations related to formaldehyde A case-control study. "CI 79(6):1221–1224.
  • Scherer, P. W., Yang, C. G., and Keyhani, K. 1996. Finite element modeling of gaseous pollutant uptake in the human nasal cavity. Ann. Biomed. Eng. 24\(suppl. 1):S–80.
  • Schreck, S., Sullivan, K. J., Ho, C. M., and Chang, H. K. 1993. Correlations between flow resistance and geometry in a model of the human nose.]. Appl. PhysioL 75:1767–1775.
  • Subramaniam, R. P., Morgan, K. T., and Kimbell, J. S. 1996. Modeling airflow in the upper respira-tory tract: Delivery of xenobiotics to the nasopharynx. Ann. Biomed. Eng. 1996.24(suppl.): S–82.
  • Swift, D. L., and Proctor, D. F. 1977. Access of air to the respiratory tract. In Respiratory defense mechanisms, eds. J. D. Brain, D. F. Proctor, and L. M. Reid, pp. 63–91. New York: Marcel Dekker.
  • Tarabichi, M., and Fanous, N. 1993. Finite element analysis of airflow in the nasal valve. Arch. Otolaryngol. Head Neck Surg. 119:638–642.
  • Torjussen, W. 1983. Nasal cancer in nickel workers. Histopathological findings and nickel concen-trations in the nasal mucosa of nickel workers, and a short review of chromium and arsenic. In Nasal tumors in animals and man: Tumor pathology, eds. G. Reznik and S. F. Stinson, pp. 33–53. Boca Raton, FL: CRC Press.
  • Virtue, J. A. 1972. The relationship between the refining of nickel and cancer of the nasal cavity. Can.]. Otolaryngol. 1:37.
  • Vogel, S. 1994. Life in moving fluids, 2nd ed. Princeton, NJ: Princeton University Press.
  • Zienkiewicz, O. C. 1977. The finite element method, 3rd ed. London: McGraw-Hill.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.