Facilitators of PrEP Persistence among Black and Latinx Transgender Women in a PrEP Demonstration Project in Southern California

References

• Baral SD, Poteat T, Strömdahl S, Wirtz AL, Guadamuz TE, Beyrer C. Worldwide burden of HIV in transgender women: a systematic review and meta-analysis. Lancet Infect Dis. 2013;13(3):214–222. doi:10.1016/S1473-3099(12)70315-8.
   PubMed Web of Science ®Google Scholar
• Herbst JH, Jacobs ED, Finlayson TJ, et al. Estimating HIV prevalence and risk behaviors of transgender persons in the United States: a systematic review. AIDS Behav. 2008;12(1):1–17. doi:10.1007/s10461-007-9299-3.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention (CDC). HIV Surveillance Report. Atlanta, GA: CDC; 2013.
   Google Scholar
• Zimmerman RS, Benotsch EG, Shoemaker S, et al. Mediational models linking psychosocial context, mental health problems, substance use, and HIV risk behaviors in transgender women. Health Psychol Behav Med. 2015;3(1):379–390. doi:10.1080/21642850.2015.1093423.
   Web of Science ®Google Scholar
• Wilson EC, Santos G-M, Raymond HF. Sexual mixing and the risk environment of sexually active transgender women: data from a respondent-driven sampling study of HIV risk among transwomen in San Francisco, 2010. BMC Infect Dis. 2014;14(1):1. doi:10.1186/1471-2334-14-430.
   PubMedGoogle Scholar
• Nuttbrock L, Hwahng S, Bockting W, et al. Lifetime risk factors for HIV/STI infections among male-to-female transgender persons. J Acquired Immune Deficiency Syndromes. 2009;52(3):417–421. doi:10.1097/QAI.0b013e3181ab6ed8.
   PubMed Web of Science ®Google Scholar
• Kenagy GP. HIV among transgendered people. AIDS Care. 2002;14(1):127–134. doi:10.1080/09540120220098008.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention. HIV Testing at CDC-Funded Sites, United States, Puerto Rico, and the US Virgin Islands, 2008–2009. Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control and Prevention; 2011.
   Google Scholar
• Austin A, Craig SL. Transgender affirmative cognitive behavioral therapy: Clinical considerations and applications. Prof Psychol: Res Pract. 2015;46(1):21–29. doi:10.1037/a0038642.
   Web of Science ®Google Scholar
• Poteat T, Reisner SL, Radix A. HIV epidemics among transgender women. Curr Opin HIV AIDS. 2014;9(2):168–173. doi:10.1097/COH.0000000000000030.
   PubMed Web of Science ®Google Scholar
• Jaspal R, Kennedy L, Tariq S. Human immunodeficiency virus and trans women: a literature review. Transgend Health. 2018;3(1):239–250. doi:10.1089/trgh.2018.0005.
   PubMedGoogle Scholar
• Becasen JS, Denard CL, Mullins MM, Higa DH, Sipe TA. Estimating the prevalence of HIV and sexual behaviors among the US transgender population: a systematic review and meta-analysis, 2006–2017. Am J Public Health. 2019;109(1):e1–e8. doi:10.2105/AJPH.2018.304727.
   PubMed Web of Science ®Google Scholar
• Jennings Mayo-Wilson L, Benotsch EG, Grigsby SR, et al. Combined effects of gender affirmation and economic hardship on vulnerability to HIV: a qualitative analysis among US adult transgender women. BMC Public Health. 2020;20(1):1–17. doi:10.1186/s12889-020-08902-3.
   PubMed Web of Science ®Google Scholar
• Ogunbajo A, Storholm ED, Ober AJ, et al. Multilevel barriers to HIV PrEP uptake and adherence among black and hispanic/latinx transgender women in Southern California. AIDS Behav. 2021;25(7):2301–2315. doi:10.1007/s10461-021-03159-2.
   PubMed Web of Science ®Google Scholar
• Fletcher JB, Kisler KA, Reback CJ. Housing status and HIV risk behaviors among transgender women in Los Angeles. Arch Sex Behav. 2014;43(8):1651–1661. doi:10.1007/s10508-014-0368-1.
   PubMed Web of Science ®Google Scholar
• Poteat T, Wirtz AL, Radix A, et al. HIV risk and preventive interventions in transgender women sex workers. The Lancet. 2015;385(9964):274–286. doi:10.1016/S0140-6736(14)60833-3.
   PubMed Web of Science ®Google Scholar
• Herman, J. L JS, Rankin S, Keisling M, Mottet L, Anafi M. The Report of the 2015 U.S. Transgender Survey. Washington, DC: National Center for Transgender Equality; 2016.
   Google Scholar
• Poteat T, Scheim A, Xavier J, Reisner S, Baral S. Global epidemiology of HIV infection and related syndemics affecting transgender people. J Acquired Immune Deficiency Syndromes. 2016;72(Suppl 3):S210–S219. doi:10.1097/QAI.0000000000001087.
   PubMedGoogle Scholar
• Operario D, Soma T, Underhill K. Sex work and HIV status among transgender women: systematic review and meta-analysis. J Acquired Immune Deficiency Syndromes. 2008;48(1):97–103. doi:10.1097/QAI.0b013e31816e3971.
   PubMed Web of Science ®Google Scholar
• Reisner SL, Radix A, Deutsch MB. Integrated and gender-affirming transgender clinical care and research. J Acquired Immune Deficiency Syndromes. 2016;72(Suppl 3):S235–S242. doi:10.1097/QAI.0000000000001088.
   PubMedGoogle Scholar
• Brennan J, Kuhns LM, Johnson AK, Belzer M, Wilson EC, Garofalo R. Syndemic theory and HIV-related risk among young transgender women: the role of multiple, co-occurring health problems and social marginalization. Am J Public Health. 2012;102(9):1751–1757. doi:10.2105/AJPH.2011.300433.
   PubMed Web of Science ®Google Scholar
• Deutsch MB, Glidden DV, Sevelius J, et al. HIV pre-exposure prophylaxis in transgender women: a subgroup analysis of the iPrEx trial. The Lancet HIV. 2015;2(12):e512–e519. doi:10.1016/S2352-3018(15)00206-4.
   PubMed Web of Science ®Google Scholar
• Grant RM, Anderson PL, McMahan V, et al. Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study. Lancet Infec Dis. 2014;14(9):820–829. doi:10.1016/S1473-3099(14)70847-3.
   PubMed Web of Science ®Google Scholar
• Poteat T, Wirtz A, Malik M, et al. A gap between willingness and uptake: findings from mixed methods research on HIV prevention among black and Latina transgender women. J Acquired Immune Deficiency Syndromes. 2019;82(2):131–140. doi:10.1097/QAI.0000000000002112.
   PubMed Web of Science ®Google Scholar
• Eaton LA, Matthews DD, Driffin DD, et al. A multi-US city assessment of awareness and uptake of pre-exposure prophylaxis (PrEP) for HIV prevention among black men and transgender women who have sex with men. Prev Sci. 2017;18(5):505–516. doi:10.1007/s11121-017-0756-6.
   PubMed Web of Science ®Google Scholar
• D'Avanzo PA, Bass SB, Brajuha J, et al. Medical mistrust and PrEP perceptions among transgender women: a cluster analysis. Behav Med. 2019;45(2):143–152. doi:10.1080/08964289.2019.1585325.
   PubMed Web of Science ®Google Scholar
• Bauermeister JA, Meanley S, Pingel E, Soler JH, Harper GW. PrEP awareness and perceived barriers among single young men who have sex with men. Curr HIV Res. 2013;11(7):520–527. doi:10.2174/1570162x12666140129100411.
   PubMed Web of Science ®Google Scholar
• Brooks RA, Landovitz RJ, Kaplan RL, Lieber E, Lee SJ, Barkley TW. Sexual risk behaviors and acceptability of HIV pre-exposure prophylaxis among HIV-negative gay and bisexual men in serodiscordant relationships: a mixed methods study. AIDS Patient Care STDS. 2012;26(2):87–94. doi:10.1089/apc.2011.0283.
   PubMed Web of Science ®Google Scholar
• Braun HM, Candelario J, Hanlon CL, et al. Transgender women living with HIV frequently take antiretroviral therapy and/or feminizing hormone therapy differently than prescribed due to drug–drug interaction concerns. LGBT Health. 2017;4(5):371–375. doi:10.1089/lgbt.2017.0057.
   PubMed Web of Science ®Google Scholar
• Lacombe-Duncan A. An intersectional perspective on access to HIV-related healthcare for transgender women. Transgend Health. 2016;1(1):137–141. doi:10.1089/trgh.2016.0018.
   PubMedGoogle Scholar
• Mizuno Y, Beer L, Huang P, Frazier EL. Factors associated with antiretroviral therapy adherence among transgender women receiving HIV medical care in the United States. LGBT Health. 2017;4(3):181–187. doi:10.1089/lgbt.2017.0003.
   PubMed Web of Science ®Google Scholar
• Rodriguez A, Agardh A, Asamoah BO. Self-reported discrimination in health-care settings based on Recognizability as transgender: a cross-sectional study among transgender US citizens. Arch Sex Behav. 2018;47(4):973–985. doi:10.1007/s10508-017-1028-z.
   PubMed Web of Science ®Google Scholar
• Sevelius JM, Patouhas E, Keatley JG, Johnson MO. Barriers and facilitators to engagement and retention in care among transgender women living with human immunodeficiency virus. Ann Behav Med. 2014;47(1):5–16. doi:10.1007/s12160-013-9565-8.
   PubMed Web of Science ®Google Scholar
• Sevelius JM, Saberi P, Johnson MO. Correlates of antiretroviral adherence and viral load among transgender women living with HIV. AIDS Care. 2014;26(8):976–982. doi:10.1080/09540121.2014.896451.
   PubMed Web of Science ®Google Scholar
• Williamson C. Providing care to transgender persons: a clinical approach to primary care, hormones, and HIV management. J Assoc Nurses AIDS Care. 2010;21(3):221–229. doi:10.1016/j.jana.2010.02.004.
   PubMed Web of Science ®Google Scholar
• Xavier J, Bradford J, Hendricks M, et al. Transgender health care access in Virginia: a qualitative study. Int J Transgenderism. 2013;14(1):3–17. doi:10.1080/15532739.2013.689513.
   Google Scholar
• Radix AE, Harris AB, Goldstein ZG. How can we improve uptake of oral HIV pre-exposure prophylaxis for transgender individuals? Expert Rev Anti Infect Ther. 2020;18(9):835–838. doi:10.1080/14787210.2020.1759418.
   PubMed Web of Science ®Google Scholar
• Wood S, Gross R, Shea JA, et al. Barriers and facilitators of PrEP adherence for young men and transgender women of color. AIDS Behav. 2019;23(10):2719–2729. doi:10.1007/s10461-019-02502-y.
   PubMed Web of Science ®Google Scholar
• Bronfenbrenner U. Ecological Systems Theory. London, United Kingdom: Jessica Kingsley Publishers; 1992.
   Google Scholar
• Sevelius JM, Keatley J, Calma N, Arnold E. ‘I am not a man’: trans-specific barriers and facilitators to PrEP acceptability among transgender women. Glob Public Health. 2016;11(7–8):1060–1075. doi:10.1080/17441692.2016.1154085.
   PubMed Web of Science ®Google Scholar
• Restar AJ, Kuhns L, Reisner SL, Ogunbajo A, Garofalo R, Mimiaga MJ. Acceptability of antiretroviral pre-exposure prophylaxis from a cohort of sexually experienced young transgender women in two US cities. AIDS Behav. 2018;22(11):3649–3657. doi:10.1007/s10461-018-2127-0.
   PubMed Web of Science ®Google Scholar
• Rebchook G, Keatley J, Contreras R, et al. The transgender women of color initiative: implementing and evaluating innovative interventions to enhance engagement and retention in HIV care. Am J Public Health. 2017;107(2):224–229. doi:10.2105/AJPH.2016.303582.
   PubMed Web of Science ®Google Scholar
• Sevelius JM. Gender affirmation: a framework for conceptualizing risk behavior among transgender women of color. Sex Roles. 2013;68(11–12):675–689. doi:10.1007/s11199-012-0216-5.
   PubMed Web of Science ®Google Scholar
• Lacombe-Duncan A, Logie CH, Newman PA, Bauer GR, Kazemi M. A qualitative study of resilience among transgender women living with HIV in response to stigma in healthcare. AIDS Care. 2020;32(8):1008–1013. doi:10.1080/09540121.2020.1728212.
   PubMed Web of Science ®Google Scholar
• Matsuno E, Israel T. Psychological interventions promoting resilience among transgender individuals: Transgender resilience intervention model (TRIM). Counseling Psychologist. 2018;46(5):632–655. doi:10.1177/0011000018787261.
   Web of Science ®Google Scholar
• Meyer IH. Resilience in the study of minority stress and health of sexual and gender minorities. Psychol Sexual Orientation Gender Diversity. 2015;2(3):209–213. doi:10.1037/sgd0000132.
   Google Scholar
• Moore DJ, Jain S, Dubé MP, et al. Randomized controlled trial of daily text messages to support adherence to preexposure prophylaxis in individuals at risk for human immunodeficiency virus: the TAPIR study. Clin Infect Dis. 2018;66(10):1566–1572. doi:10.1093/cid/cix1055.
   PubMed Web of Science ®Google Scholar
• Anderson PL, Liu AY, Castillo-Mancilla JR, et al. Intracellular tenofovir-diphosphate and emtricitabine-triphosphate in dried blood spots following directly observed therapy. Antimicrob Agents Chemother. 2018;62(1), e01710-17. doi:10.1128/AAC.01710-17.
   Web of Science ®Google Scholar
• Landovitz RJ, Beymer M, Kofron R, et al. Plasma tenofovir-levels to support adherence to TDF/FTC pre-exposure prophylaxis for HIV prevention in MSM in Los Angeles, California. J Acquired Immune Deficiency Syndromes (1999). 2017;76(5):501–511. doi:10.1097/QAI.0000000000001538.
   PubMed Web of Science ®Google Scholar
• Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care. 2007;19(6):349–357. doi:10.1093/intqhc/mzm042.
   PubMed Web of Science ®Google Scholar
• Mayring P. Qualitative content analysis. Companion Qual Res. 2004;1:159–176.
   Google Scholar
• Ryan GW, Bernard HR. Techniques to identify themes. Field Methods. 2003;15(1):85–109. doi:10.1177/1525822X02239569.
   Google Scholar
• Applied Thematic Analysis. Thousand Oaks, CA; 2012. https://methods.sagepub.com/book/applied-thematic-analysis. Accessed December 28, 2021.
   Google Scholar
• Braun V, Clarke V. Using thematic analysis in psychology. Qualitative Research in Psychology. 2006;3(2):77–101. doi:10.1191/1478088706qp063oa.
   Google Scholar
• Edhlund B, McDougall A. Nvivo 12 Essentials. Lulu.com; 2019.
   Google Scholar
• Elo S, Kyngäs H. The qualitative content analysis process. J Adv Nurs. 2008;62(1):107–115. doi:10.1111/j.1365-2648.2007.04569.x.
   PubMed Web of Science ®Google Scholar
• Garnett M, Hirsch-Moverman Y, Franks J, Hayes-Larson E, El-Sadr WM, Mannheimer S. Limited awareness of pre-exposure prophylaxis among black men who have sex with men and transgender women in New York city. AIDS Care. 2018;30(1):9–17. doi:10.1080/09540121.2017.1363364.
   PubMed Web of Science ®Google Scholar
• Hoagland B, De Boni RB, Moreira RI, et al. Awareness and willingness to use pre-exposure prophylaxis (PrEP) among men who have sex with men and transgender women in Brazil. AIDS Behav. 2017;21(5):1278–1287. doi:10.1007/s10461-016-1516-5.
   PubMed Web of Science ®Google Scholar
• Wilson E, Chen Y-H, Pomart WA, Arayasirikul S. Awareness, interest, and HIV pre-exposure prophylaxis candidacy among young transwomen. AIDS Patient Care STDS. 2016;30(4):147–150. doi:10.1089/apc.2015.0266.
   PubMed Web of Science ®Google Scholar
• Reback CJ, Clark KA, Rünger D, Fehrenbacher AE. A promising PrEP navigation intervention for transgender women and men who have sex with men experiencing multiple syndemic health disparities. J Community Health. 2019;44(6):1193–1203. doi:10.1007/s10900-019-00705-x.
   PubMed Web of Science ®Google Scholar
• Kullgren JT, Troxel AB, Loewenstein G, et al. Individual-versus group-based financial incentives for weight loss: a randomized, controlled trial. Ann Intern Med. 2013;158(7):505–514. doi:10.7326/0003-4819-158-7-201304020-00002.
   PubMed Web of Science ®Google Scholar
• Fryer RG, Levitt SD, List J, Sadoff S. Enhancing the Efficacy of Teacher Incentives through Loss Aversion: A Field Experiment. Cambridge, MA: National Bureau of Economic Research; 2012.
   Google Scholar
• Babcock P, Bedard K, Charness G, Hartman J, Royer H. Letting down the team? Social effects of team incentives. J Eur Econ Assoc. 2015;13(5):841–870. doi:10.1111/jeea.12131.
   Web of Science ®Google Scholar
• Pinto RM, Melendez RM, Spector AY. Male-to-female transgender individuals building social support and capital from within a gender-focused network. J Gay Lesbian Soc Serv. 2008;20(3):203–220. doi:10.1080/10538720802235179.
   PubMedGoogle Scholar
• Sevelius JM, Glidden DV, Deutsch M, et al. Uptake, retention, and adherence to pre-exposure prophylaxis (PrEP) in TRIUMPH: a peer-led PrEP demonstration project for transgender communities in Oakland and Sacramento, California. J Acquired Immune Deficiency Syndromes. 2021;88(S1):S27–S38. doi:10.1097/QAI.0000000000002808.
   PubMedGoogle Scholar
• Sevelius JM, Xavier J, Chakravarty D, Keatley J, Shade S, Rebchook G, Correlates of engagement in HIV care among transgender women of color in the United States of America. AIDS Behav. 2021;25(Suppl 1):3–10. doi:10.1007/s10461-021-03306-9.
   PubMed Web of Science ®Google Scholar
• Sevelius J, Chakravarty D, Neilands TB, et al. Evidence for the model of gender affirmation: the role of gender affirmation and healthcare empowerment in viral suppression among transgender women of color living with HIV. AIDS Behav. 2021;25(Suppl 1):64–68. doi:10.1007/s10461-019-02544-2.
   PubMed Web of Science ®Google Scholar
• UCSF Transgender Care DoFaCM, University of California San Francisco. Guidelines for the Primary and Gender-Affirming Care of Transgender and Gender Nonbinary People. San Francisco, CA; 2016.
   Google Scholar
• Neumann MS, Finlayson TJ, Pitts NL, Keatley J. Comprehensive HIV Prevention for Transgender Persons. Am J Public Health. 2017;107(2):207–212. doi:10.2105/AJPH.2016.303509.
   PubMed Web of Science ®Google Scholar
• James S, Herman J, Rankin S, Keisling M, Mottet L, Anafi M. The Report of the 2015 US Transgender Survey. Washington, DC: National Center for Transgender Equality; 2016.
   Google Scholar
• Poteat T, Scheim A, Xavier J, Reisner S, Baral S. Global epidemiology of HIV infection and related syndemics affecting transgender people. J Acquired Immune Deficiency Syndromes (1999). 2016;72(3):S210–S219. doi:10.1097/QAI.0000000000001087.
   PubMedGoogle Scholar
• Reisner SL, Radix A, Deutsch MB. Integrated and gender-affirming transgender clinical care and research. J Acquired Immune Deficiency Syndromes (1999). 2016;72(3):S235–S242. doi:10.1097/QAI.0000000000001088.
   PubMedGoogle Scholar