Efficacy and safety of 308-nm Excimer lamp combined with Tacrolimus 0.1% ointment vs Tacrolimus 0.1% ointment as monotherapy in treating children with limited vitiligo: a randomized controlled trial

References

• Halder RM. Childhood vitiligo. Clin Dermatol. 1997;15(6):1–7. doi: 10.1016/s0738-081x(97)00131-4.
   Web of Science ®Google Scholar
• Kovacs S. Vitiligo. J Am Acad Dermatol. 1998;38(5 Pt 1):647–668. doi: 10.1016/s0190-9622(98)70194-x.
   PubMed Web of Science ®Google Scholar
• Mosher DB, Fitzpatrick TB, Ortonne JP, et al. Hypomelanosis and hypermelanosis. In: Fitzpatrick, TB, Eisen, AZ, Wolff, K, Freedberg, IM, Austen, KF, eds. Dermatology in general medicine. New York: McGraw-Hill, 1999: 945–1017.
   Google Scholar
• Cho S, Kang H-C, Hahm J-H. Characteristics of vitiligo in korean children. Pediatr Dermatol. 2000;17(3):189–193. doi: 10.1046/j.1525-1470.2000.01749.x.
   PubMed Web of Science ®Google Scholar
• Lacour J-P. Vitiligo in children: a serious psychological repercussion, in spite of its harmlessness. Rev Prat Med Gen. 1994;8:37–44.
   Google Scholar
• Grimes PE. Diseases of hypopigmentation. In: Sams WM, Lynch PJ, editors. Principles and practice of dermatology. 2nd ed. New York: Churchill-Livingstone; 1996. p. 873–885.
   Google Scholar
• Grimes PE. Vitiligo: an overview of therapeutic approaches. Dermatol Clin. 1993;11(2):325–338. doi: 10.1016/S0733-8635(18)30271-7.
   PubMed Web of Science ®Google Scholar
• Reitamo S, Wollenberg A, Schöpf E, et al. Safety and efficacy of one year of tacrolimus ointment monotherapy in adults with atopic dermatitis. Arch Dermatol. 2000;136(8):999–1006. doi: 10.1001/archderm.136.8.999.
   PubMedGoogle Scholar
• Lawrence I. Tacrolimus (FK 506) experience in dermatology. Dermatol Ther. 1998;5:74–84.
   Google Scholar
• Lepe V, Moncada B, Castanedo-Cazares JP, et al. A double blind randomized trial of 0.1% tacrolimus vs 0.05% clobetasol for the treatment of childhood vitiligo. Arch Dermatol. 2003;139(5):581–585. doi: 10.1001/archderm.139.5.581.
   PubMedGoogle Scholar
• Alshiyab D, Al-Qarqaz F, Ba-Shammakh S, et al. Comparison of the efficacy of tacrolimus 0.1% ointment vs calcipotriol/betamethasone in combination with NBUVB in treatment of vitiligo. J Dermatolog Treat. 2023;34(1):2252119. doi: 10.1080/09546634.2023.225211.
   PubMed Web of Science ®Google Scholar
• Njoo MD, Spuls PI, Bos JD, et al. Nonsurgical repigmentation therapies in vitiligo. Meta-analysis of the literature. Arch Dermatol. 1998;134(12):1532–1540. doi: 10.1001/archderm.134.12.1532.
   PubMedGoogle Scholar
• Le Duff F, Fontas E, Giacchero D, et al. 308-nm excimer lamp vs. 308-nm excimer laser for treating vitiligo: a randomized study. Br J Dermatol. 2010;163(1):188–192. doi: 10.1111/j.1365-2133.2010.09778.x.
   PubMed Web of Science ®Google Scholar
• Do JE, Shin JY, Kim DY, et al. The effect of 308nm excimer laser on segmental vitiligo: a retrospective study of 80patients with segmental vitiligo. Photodermatol Photoimmunol Photomed. 2011;27(3):147–151. doi: 10.1111/j.1600-0781.2011.00587.x.
   PubMed Web of Science ®Google Scholar
• Bae JM, Yoo HJ, Kim H, et al. Combination therapy with 308-nm excimer laser, topical tacrolimus, and short-term systemic corticosteroids for segmental vitiligo: a retrospective study of 159 patients. J Am Acad Dermatol. 2015;73(1):76–82. doi: 10.1016/j.jaad.2015.04.008.
   PubMed Web of Science ®Google Scholar
• Passeron T, Ortonne JP. Use of the 308-nm excimer laser for psoriasis and vitiligo. Clin Dermatol. 2006;24(1):33–42. doi: 10.1016/j.clindermatol.2005.10.024.
   PubMed Web of Science ®Google Scholar
• Li L, Liang Y, Hong J, et al. The effectiveness of topical therapy combined with 308-nm excimer laser on vitiligo compared to excimer laser monotherapy in pediatric patients. Pediatr Dermatol. 2019;36(1):e53–e55.
   PubMed Web of Science ®Google Scholar
• Grimes PE, Soriano T, Dytoc MT. Topical tacrolimus for repigmentation of vitiligo. J Am Acad Dermatol. 2002;47(5):789–791. doi: 10.1067/mjd.2002.126250.
   PubMed Web of Science ®Google Scholar
• Kanwar AJ, Dogra S, Parsad D. Topical tacrolimus for treatment of childhood vitiligo in Asians. Clin Exp Dermatol. 2004;29(6):589–592. doi: 10.1111/j.1365-2230.2004.01632.x.
   PubMed Web of Science ®Google Scholar
• Silverberg NB, Lin P, Travis L, et al. Tacrolimus ointment promotes repigmentation of vitiligo in children: a review of 57 cases. J Am Acad Dermatol. 2004;51(5):760–766. doi: 10.1016/j.jaad.2004.05.036.
   PubMed Web of Science ®Google Scholar
• Xu AE, Zhang DM, Wei XD, et al. Efficacy and safety of tacrolimus cream 0.1% in the treatment of vitiligo. Int J Dermatol. 2009;48(1):86–90. Jan). doi: 10.1111/j.1365-4632.2009.03852.x.
   PubMed Web of Science ®Google Scholar
• Ho N, Pope E, Weinstein M, et al. A double-blind, randomized, placebo-controlled trial of topical tacrolimus 0·1% vs. clobetasol propionate 0·05% in childhood vitiligo. Br J Dermatol. 2011;165(3):626–632. doi: 10.1111/j.1365-2133.2011.10351.x.
   PubMed Web of Science ®Google Scholar
• Park KK, Liao W, Murase JE. A review of monochromatic excimer light in vitiligo. Br J Dermatol. 2012;167(3):468–478. doi: 10.1111/j.1365-2133.2012.11008.x.
   PubMed Web of Science ®Google Scholar
• Hong SB, Park HH, Lee MH. Short-term effects of 308-nm xenon-chloride excimer laser and narrow-band ultraviolet B in the treatment of vitiligo: a comparative study. J Korean Med Sci. 2005;20(2):273–278. doi: 10.3346/jkms.2005.20.2.273.
   PubMed Web of Science ®Google Scholar
• Lan CC, Chen GS, Chiou MH, et al. FK506 promotes melanocyte and melanoblast growth and creates a favorable milieu for cell migration via keratinocytes: possible mechanisms of how tacrolimus ointment induces repigmentation in patients with vitiligo. Br J Dermatol. 2005;153(3):498–505. doi: 10.1111/j.1365-2133.2005.06739.x.
   PubMed Web of Science ®Google Scholar
• Lee KY, Jeon SY, Hong JW, et al. Endothelin-1 enhances the proliferation of normal human melanocytes in a paradoxical manner from the TNF-alpha-inhibited condition, but tacrolimus promotes exclusively the cellular migration without proliferation: a proposed action mechanism for combination therapy of phototherapy and topical tacrolimus in vitiligo treatment. J Eur Acad Dermatol Venereol. 2013;27(5):609–616. doi: 10.1111/j.1468-3083.2012.04498.x.
   PubMed Web of Science ®Google Scholar
• Passeron T, Ostovari N, Zakaria W, et al. Topical tacrolimus and the 308-nm excimer laser: a synergistic combination for the treatment of vitiligo. Arch Dermatol. 2004;140(9):1065–1069. doi: 10.1001/archderm.140.9.1065.
   PubMedGoogle Scholar
• Kawalek AZ, Spencer JM, Phelps RG. Combined excimer laser and topical tacrolimus for the treatment of vitiligo: a pilot study. Dermatol Surg. 2004;30(2):130–135. doi: 10.1097/00042728-200402000-00002.
   PubMed Web of Science ®Google Scholar
• Bae JM, Hong BY, Lee JH, et al. The efficacy of 308-nm excimer laser/light (EL) and topical agent combination therapy versus EL monotherapy for vitiligo: a systematic review and meta-analysis of randomized controlled trials (RCTs). J Am Acad Dermatol. 2016;74(5):907–915. doi: 10.1016/j.jaad.2015.11.044.
   PubMed Web of Science ®Google Scholar
• Khullar G, Kanwar AJ, Singh S, et al. Comparison of efficacy and safety profile of topical calcipotriol ointment in combination with NB- UVB vs. NB-UVB alone in the treatment of vitiligo: a 24-week prospective right-left comparative clinical trial. J Eur Acad Dermatol Venereol. 2015;29(5):925–932. doi: 10.1111/jdv.12726.
   PubMed Web of Science ®Google Scholar
• Lotti T, Buggiani G, Troiano M, et al. Targeted and combination treatments for vitiligo. Comparative evaluation in 458 subjects. Dermatol Ther. 2008;21(1):S20–S26. doi: 10.1111/j.1529-8019.2008.00198.x.
   PubMedGoogle Scholar
• Fai D, Cassano N, Vena GA. Narrow-band UVB phototherapy combined with tacrolimus ointment in vitiligo: review of 110 patients. J Eur Acad Dermatol Venereol. 2007;21(7):916–920. doi: 10.1111/j.1468-3083.2006.02101.x.
   PubMed Web of Science ®Google Scholar
• Choi CW, Chang SE, Bak H, et al. Topical immunomodulators are effective for treatment of vitiligo. J Dermatol. 2008;35(8):503–507. doi: 10.1111/j.1346-8138.2008.00511.x.
   PubMed Web of Science ®Google Scholar
• Baltás E, Nagy P, Bónis B, et al. Repigmentation of localized vitiligo with the xenon chloride laser. Br J Dermatol. 2001;144(6):1266–1267. doi: 10.1046/j.1365-2133.2001.04248.x.
   PubMed Web of Science ®Google Scholar
• Taneja A, Trehan M, Taylor CR. 308-nm excimer laser for the treatment of localized vitiligo. Int J Dermatol. 2003;42(8):658–662. doi: 10.1046/j.1365-4362.2003.01997.x.
   PubMed Web of Science ®Google Scholar
• Ostovari N, Passeron T, Zakaria W, et al. Treatment of vitiligo by 308-nm excimer laser: an evaluation of variables affecting treatment response. Lasers Surg Med. 2004;35(2):152–156. doi: 10.1002/lsm.20057.
   PubMed Web of Science ®Google Scholar
• Hartmann A, Bröcker EB, Hamm H. Occlusive treatment enhances efficacy of tacrolimus 0.1% ointment in adult patients with vitiligo: results of a placebo-controlled 12-months prospective study. Acta Derm Venereol. 2008;88(5):474–479. doi: 10.2340/00015555-0464.
   PubMed Web of Science ®Google Scholar
• Tran C, Lübbe J, Sorg O, et al. Topical calcineurin inhibitors decrease the production of UVB-induced thymine dimers from hairless mouse epidermis. Dermatol. 2005;211(4):341–347. doi: 10.1159/000088505.
   PubMed Web of Science ®Google Scholar