Adult, adolescent, and caregiver preferences for attributes of topical treatments for mild-to-moderate atopic dermatitis: a discrete-choice experiment

References

• Bechman K, Yates M, Galloway JB. The new entries in the therapeutic armamentarium: the small molecule JAK inhibitors. Pharmacol Res. 2019;153:1. doi: 10.1016/j.phrs.2020.104634.
   Web of Science ®Google Scholar
• Garside R, Stein K, Castelnuovo E, et al. The effectiveness and cost-effectiveness of pimecrolimus and tacrolimus for atopic eczema: a systematic review and economic evaluation. Health Technol Assess. 2005;9(29):1–8. doi: 10.3310/hta9290.
   Web of Science ®Google Scholar
• Newton L, DeLozier AM, Griffiths PC, et al. Exploring content and psychometric validity of newly developed assessment tools for itch and skin pain in atopic dermatitis. J Patient Rep Outcomes. 2019;3(1):42. doi: 10.1186/s41687-019-0128-z.
   PubMedGoogle Scholar
• Silverberg JI, Gelfand JM, Margolis DJ, et al. Pain is a common and burdensome symptom of atopic dermatitis in United States adults. J Allergy Clin Immunol Pract. 2019;7(8):2699–2706.e2697. doi: 10.1016/j.jaip.2019.05.055.
   PubMed Web of Science ®Google Scholar
• Suárez-Fariñas M, Tintle SJ, Shemer A, et al. Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities. J Allergy Clin Immunol. 2011;127(4):954–964. doi: 10.1016/j.jaci.2010.12.1124.
   PubMed Web of Science ®Google Scholar
• Vakharia PP, Chopra R, Sacotte R, et al. Burden of skin pain in atopic dermatitis. Ann Allergy Asthma Immunol. 2017;119(6):548 e543–552 e543. doi: 10.1016/j.anai.2017.09.076.
   PubMed Web of Science ®Google Scholar
• Barbarot S, Auziere S, Gadkari A, et al. Epidemiology of atopic dermatitis in adults: results from an international survey. Allergy. 2018;73(6):1284–1293. doi: 10.1111/all.13401.
   PubMed Web of Science ®Google Scholar
• Carroll CL, Balkrishnan R, Feldman SR, et al. The burden of atopic dermatitis: impact on the patient, family, and society. Pediatr Dermatol. 2005;22(3):192–199. doi: 10.1111/j.1525-1470.2005.22303.x.
   PubMed Web of Science ®Google Scholar
• Eckert L, Gupta S, Amand C, et al. Impact of atopic dermatitis on health-related quality of life and productivity in adults in the United States: an analysis using the national health and wellness survey. J Am Acad Dermatol. 2017;77(2):274–279 e273. doi: 10.1016/j.jaad.2017.04.019.
   PubMed Web of Science ®Google Scholar
• Eichenfield LF, Tom WL, Berger TG, et al. Guidelines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies. J Am Acad Dermatol. 2014;71(1):116–132. doi: 10.1016/j.jaad.2014.03.023.
   PubMed Web of Science ®Google Scholar
• Baron S, Cohen S, Archer C. Guidance on the diagnosis and clinical management of atopic eczema. Clin Exp Dermatol. 2012;37(Suppl 1):7–12. doi: 10.1111/j.1365-2230.2012.04336.x.
   PubMedGoogle Scholar
• Boguniewicz M, Fonacier L, Guttman-Yassky E, et al. Atopic dermatitis yardstick: practical recommendations for an evolving therapeutic landscape. Ann Allergy Asthma Immunol. 2018;120(1):10 e12–22 e12. doi: 10.1016/j.anai.2017.10.039.
   PubMed Web of Science ®Google Scholar
• Sidbury R, Davis DM, Cohen DE, et al. Guidelines of care for the management of atopic dermatitis: section 3. Management and treatment with phototherapy and systemic agents. J Am Acad Dermatol. 2014;71(2):327–349. doi: 10.1016/j.jaad.2014.03.030.
   PubMed Web of Science ®Google Scholar
• Sidbury R, Tom WL, Bergman JN, et al. Guidelines of care for the management of atopic dermatitis: section 4. Prevention of disease flares and use of adjunctive therapies and approaches. J Am Acad Dermatol. 2014;71(6):1218–1233. doi: 10.1016/j.jaad.2014.08.038.
   PubMed Web of Science ®Google Scholar
• Johnson FR, Zhou M. Patient preferences in regulatory benefit-risk assessments: a US perspective. Value Health. 2016;19(6):741–745. doi: 10.1016/j.jval.2016.04.008.
   PubMed Web of Science ®Google Scholar
• Mühlbacher AC, Juhnke C, Beyer AR, et al. Patient-focused benefit-risk analysis to inform regulatory decisions: the European union perspective. Value Health. 2016;19(6):734–740. doi: 10.1016/j.jval.2016.04.006.
   PubMed Web of Science ®Google Scholar
• Elwyn G, Frosch D, Rollnick S. Dual equipoise shared decision making: definitions for decision and behaviour support interventions. Implement Sci. 2009;4(1):75. doi: 10.1186/1748-5908-4-75.
   PubMedGoogle Scholar
• Boeri M, Sutphin J, Hauber B, et al. Quantifying patient preferences for systemic atopic dermatitis treatments using a discrete-choice experiment. J Dermatolog Treat. 2020;33(3):1449–1458.
   PubMed Web of Science ®Google Scholar
• Okubo Y, Ho KA, Fifer S, et al. Patient and physician preferences for atopic dermatitis injection treatments in Japan. J Dermatolog Treat. 2020;31(8):821–830. doi: 10.1080/09546634.2019.1623860.
   PubMed Web of Science ®Google Scholar
• Myers K, Silverberg JI, Parasuraman S, et al. Treatment preferences among patients with mild-to-moderate atopic dermatitis. J Dermatolog Treat. 2023;34(1):2215356.
   PubMed Web of Science ®Google Scholar
• Ervin C, Crawford R, Evans E, et al. Patient and caregiver preferences on treatment attributes for atopic dermatitis. J Dermatol Treat. 2022;33(4):2225–2233.
   PubMed Web of Science ®Google Scholar
• Charman CR, Venn AJ, Ravenscroft JC, et al. Translating patient-oriented eczema measure (POEM) scores into clinical practice by suggesting severity strata derived using anchor-based methods. Br J Dermatol. 2013;169(6):1326–1332. doi: 10.1111/bjd.12590.
   PubMed Web of Science ®Google Scholar
• Charman CR, Venn AJ, Williams HC. The patient-oriented eczema measure: development and initial validation of a new tool for measuring atopic eczema severity from the patients’ perspective. Arch Dermatol. 2004;140(12):1513–1519. doi: 10.1001/archderm.140.12.1513.
   PubMedGoogle Scholar
• Simpson E, Beck LA, Gadkari A, et al. Defining a responder on the peak pruritus numerical rating scale (NRS) in patients with moderate-to-severe atopic dermatitis: detailed analysis from randomized trials of dupilumab. J Am Acad Dermatol. 2017;76(6):AB93.
   Web of Science ®Google Scholar
• Yosipovitch G, Reaney M, Mastey V, et al. Peak pruritus numerical rating scale: psychometric validation and responder definition for assessing itch in moderate-to-severe atopic dermatitis. Br J Dermatol. 2019;181(4):761–769. doi: 10.1111/bjd.17744.
   PubMed Web of Science ®Google Scholar
• Moret L, Anthoine E, Aubert-Wastiaux H, et al. TOPICOP©: a new scale evaluating topical corticosteroid phobia among atopic dermatitis outpatients and their parents. PLoS One. 2013;8(10):e76493. doi: 10.1371/journal.pone.0076493.
   PubMed Web of Science ®Google Scholar
• Hauber AB, González JM, Groothuis-Oudshoorn CG, et al. Statistical methods for the analysis of discrete choice experiments: a report of the ISPOR conjoint analysis good research practices task force. Value Health. 2016;19(4):300–315. doi: 10.1016/j.jval.2016.04.004.
   PubMed Web of Science ®Google Scholar
• Greene WH. Econometric analysis. 7th ed. Harlow: Pearson; 2012.
   Google Scholar
• Hole AR. A comparison of approaches to estimating confidence intervals for willingness to pay measures. Health Econ. 2007;16(8):827–840. doi: 10.1002/hec.1197.
   PubMed Web of Science ®Google Scholar
• Reich A, Chatzigeorkidis E, Zeidler C, et al. Tailoring the cut-off values of the visual analogue scale and numeric rating scale in itch assessment. Acta Derm Venereol. 2017;97(6):759–760. doi: 10.2340/00015555-2642.
   PubMed Web of Science ®Google Scholar
• Gerner T, Haugaard JH, Vestergaard C, et al. Healthcare utilization in Danish children with atopic dermatitis and parental topical corticosteroid phobia. Pediatr Allergy Immunol. 2020;32(2):331–341. doi: 10.1111/pai.13394.
   PubMed Web of Science ®Google Scholar
• Stalder J-F, Aubert H, Anthoine E, et al. Topical corticosteroid phobia in atopic dermatitis: international feasibility study of the TOPICOP score. Allergy. 2017;72(11):1713–1719. doi: 10.1111/all.13189.
   PubMed Web of Science ®Google Scholar
• Silverberg JI, Gelfand JM, Margolis DJ, et al. Patient burden and quality of life in atopic dermatitis in US adults: a population-based cross-sectional study. Ann Allergy Asthma Immunol. 2018;121(3):340–347. doi: 10.1016/j.anai.2018.07.006.
   PubMed Web of Science ®Google Scholar
• Ständer S, Yosipovitch G, Bushmakin AG, et al. Examining the association between pruritus and quality of life in patients with atopic dermatitis treated with crisaborole. J Eur Acad Dermatol Venereol. 2019;33(9):1742–1746. doi: 10.1111/jdv.15712.
   PubMed Web of Science ®Google Scholar
• Simpson EL, Bieber T, Eckert L, et al. Patient burden of moderate to severe atopic dermatitis (AD): insights from a phase 2b clinical trial of dupilumab in adults. J Am Acad Dermatol. 2016;74(3):491–498. doi: 10.1016/j.jaad.2015.10.043.
   PubMed Web of Science ®Google Scholar
• Augustin M, Langenbruch A, Blome C, et al. Characterizing treatment-related patient needs in atopic eczema: insights for personalized goal orientation. J Eur Acad Dermatol Venereol. 2020;34(1):142–152. doi: 10.1111/jdv.15919.
   PubMed Web of Science ®Google Scholar
• Curry ZA, Johnson MC, Unrue EL, et al. Caregiver willingness to treat atopic dermatitis is not much improved by anchoring. J Dermatolog Treat. 2019;30(5):471–474. doi: 10.1080/09546634.2018.1530442.
   PubMed Web of Science ®Google Scholar
• Thyssen JP, Halling-Sonderby AS, Wu JJ, et al. Pain severity and use of analgesic medication in adults with atopic dermatitis: a cross-sectional study. Br J Dermatol. 2020;182(6):1430–1436. doi: 10.1111/bjd.18557.
   PubMed Web of Science ®Google Scholar
• Bridges JF, Hauber AB, Marshall D, et al. Conjoint analysis applications in health–a checklist: a report of the ISPOR good research practices for conjoint analysis task force. Value Health. 2011;14(4):403–413. doi: 10.1016/j.jval.2010.11.013.
   PubMed Web of Science ®Google Scholar
• Johnson FR, Lancsar E, Marshall D, et al. Constructing experimental designs for discrete-choice experiments: report of the ISPOR conjoint analysis experimental design good research practices task force. Value Health. 2013;16(1):3–13. doi: 10.1016/j.jval.2012.08.2223.
   PubMed Web of Science ®Google Scholar
• Ho MP, Gonzalez JM, Lerner HP, et al. Incorporating patient-preference evidence into regulatory decision making. Surg Endosc. 2015;29(10):2984–2993. doi: 10.1007/s00464-014-4044-2.
   PubMed Web of Science ®Google Scholar