Advanced search
Publication Cover
Journal of Dermatological Treatment Volume 35, 2024 - Issue 1
Submit an article Journal homepage
560
Views
0
CrossRef citations to date
0
Altmetric
Case Report

Successful treatment of recalcitrant generalized pustular psoriasis of pregnancy with spesolimab

Chenxin Yanga Department of Dermatology, Peking University First Hospital, Beijing, China;b National Clinical Research Center for Skin and Immune Diseases, Beijing, China;c Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, ChinaView further author information
,
Yang Wanga Department of Dermatology, Peking University First Hospital, Beijing, China;b National Clinical Research Center for Skin and Immune Diseases, Beijing, China;c Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, ChinaView further author information
,
Ruoyu Lia Department of Dermatology, Peking University First Hospital, Beijing, China;b National Clinical Research Center for Skin and Immune Diseases, Beijing, China;c Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, ChinaView further author information
,
Ping Tua Department of Dermatology, Peking University First Hospital, Beijing, China;b National Clinical Research Center for Skin and Immune Diseases, Beijing, China;c Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, ChinaView further author information
&
Ruojun Wanga Department of Dermatology, Peking University First Hospital, Beijing, China;b National Clinical Research Center for Skin and Immune Diseases, Beijing, China;c Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, ChinaCorrespondence[email protected]
View further author information
Article: 2334791 | Received 15 Feb 2024, Accepted 20 Mar 2024, Published online: 02 Apr 2024

References

  • Babuna Kobaner G, Polat Ekinci A. Infliximab for the treatment of recalcitrant generalized pustular psoriasis of pregnancy: report of a challenging case. Dermatol Ther. 2020;33(4):e13571. doi: 10.1111/dth.13571.
  • Seishima M, Fujii K, Mizutani Y. Generalized pustular psoriasis in pregnancy: current and future treatments. Am J Clin Dermatol. 2022;23(5):661–671. doi: 10.1007/s40257-022-00698-9.
  • Murrieta-Coxca JM, Rodríguez-Martínez S, Cancino-Diaz ME, et al. IL-36 cytokines: regulators of inflammatory responses and their emerging role in immunology of reproduction. Int J Mol Sci. 2019;20(7):1649. doi: 10.3390/ijms20071649.
  • Johnston A, Xing X, Wolterink L, et al. IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis. J Allergy Clin Immunol. 2017;140(1):109–120. doi: 10.1016/j.jaci.2016.08.056.
  • Kodali N, Blanchard I, Kunamneni S, et al. Current management of generalized pustular psoriasis. Exp Dermatol. 2023;32(8):1204–1218. doi: 10.1111/exd.14765.
  • Baum P, Visvanathan S, Garcet S, et al. Pustular psoriasis: molecular pathways and effects of spesolimab in generalized pustular psoriasis. J Allergy Clin Immunol. 2022;149(4):1402–1412. doi: 10.1016/j.jaci.2021.09.035.
  • Murrieta-Coxca JM, Gutiérrez-Samudio RN, El-Shorafa HM, et al. Role of IL-36 cytokines in the regulation of angiogenesis potential of trophoblast cells. Int J Mol Sci. 2020;22(1):285. doi: 10.3390/ijms22010285.
  • Bachelez H, Choon SE, Marrakchi S, et al. Trial of spesolimab for generalized pustular psoriasis. N Engl J Med. 2021;385(26):2431–2440. doi: 10.1056/NEJMoa2111563.
  • Iznardo H, Puig L. Exploring the role of IL-36 cytokines as a new target in psoriatic disease. Int J Mol Sci. 2021;22(9):4344. doi: 10.3390/ijms22094344.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.