286
Views
40
CrossRef citations to date
0
Altmetric
Research Article

Poly(l-lactide-co-glycolide) nanospheres conjugated with a nuclear localization signal for delivery of plasmid DNA

, , , &
Pages 190-198 | Received 18 Aug 2006, Accepted 29 Nov 2006, Published online: 08 Oct 2008

References

  • Auricchio A, Rivera VM, Clackson T, O'Connor EE, Maguire AM, Tolentino MJ, Bennett J, Wilson JM. Pharmacological regulation of protein expression from adeno-associated viral vectors in the eye. Mol Ther 2002; 2: 238–242
  • Benns JM, Maheshwari A, Furgeson DY, Mahato RI, Kim SW. Folate-PEG-folate-graft-polyethylenimine-based gene delivery. J Drug Target 2001; 9: 123–139
  • Cavazzana-Calvo M, Hacein-Bey S, De Saint Basile G, Gross F, Yvon E, Nusbaum P, Selz F, Hue C, Certain S, Casanova JL, Bousso P, Le Deist F, Fischer A. Gene therapy of human severe combined immune deficiency (SCID)-X1 disease. Science 2000; 288: 669–672
  • Christiano R. Viral and non-viral vectors for cancer gene therapy. Anticancer Res 1998; 18: 3142–3246
  • Cohen H, Levy RJ, Gao J, Fishbein I, Kousaev V, Sosnowski S, Slomkowski S, Golomb G. Sustained delivery and expression of DNA encapsulated in polymeric nanoparticles. Gene Ther 2000; 7: 1896–1905
  • Davidson BL, Stein CS, Heth JA, Martins I, Kotin RM, Derksen TA, Zabner J, Ghodsi A, Chiorini JA. Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system. Proc Natl Acad Sci USA 2000; 97: 3428–3432
  • Diaz RV, Soriano I, Delgado A, Llabres M, Evora C. Effect of surfactant agents on the release of 125I-bovine calcitonin from PLGA microspheres: In vitro–in vivo study. J Control Release 1997; 43: 59–64
  • Godbey WT, Wu KK, Mikos AG. Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery. Proc Natl Acad Sci USA 1999; 96(9)5177–5181
  • Jain RA. The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 2000; 23: 2475–2490
  • Jiao SS, Gurevich V, Wolff JA. Long-term correction of rat model of Parkinsons-disease by gene therapy. Nature 1993; 362: 450–453
  • Kim IS, Lee SK, Park YM, Lee YB, Shin SC, Lee KC, Oh IJ. Physicochemical characterization of poly(l-lactic acid) and poly(d,l-lactide-co-glycolide) nanoparticles with polyethylenimine as gene delivery carrier. Int J Pharm 2005; 298: 255–262
  • Krisky DM, Wolfe D, Goins WF, Marconi PC, Ramakrishnan R, Mata M, Rouse RJ, Fink DJ, Glorioso JC. Deletion of multiple immediate-early genes from herpes simplex virus reduces cytotoxicity and permits long-term gene expression in neurons. Gene Ther 1998; 12: 1593–1603
  • Ledley FD. Nonviral gene therapy: The promise of genes as pharmaceutical products. Hum Gene Ther 1995; 6: 1129–1144
  • Lee M, Kim SW. Polymeric gene carrier. Pharm News 2002; 9: 407–415
  • Lemmouchi Y, Schacht E, Kageruka P, De Deken R, Diarra B, Diall O, Geerts S. Biodegradable polyesters for controlled release of trypanocidal drugs: In vitro and in vivo studies. Biomaterials 1998; 19: 1827–1837
  • Litzinger DC, Brown JM, Wala I, Kaufman SA, Van GY, Farrell CL, Collins D. Fate of cationic liposomes and their complex with oligonucleotide in vivo. Biochim Biophys Acta 1996; 1281: 139–149
  • Ludtke JJ, Zhang G, Sebestyen MG, Wolff JA. A nuclear localization signal can enhance both the nuclear transport and expression of 1 kb DNA. J Cell Sci 1999; 112: 2033–2041
  • Mir B, Piedrahita JA. Nuclear localization signal and cell synchrony enhance gene targeting efficiency in primary fetal fibroblasts. Nucleic Acids Res 2004; 32: e25
  • Niidome T, Huang L. Gene therapy progress and prospects: Nonviral vectors. Gene Ther 2002; 9: 1647–1652
  • Panyam J, Zhou WZ, Prabha S, Sahoo SK, Labhasetwar V. Rapid endo-lysosomal escape of poly(d,l-lactide-co-glycolide) nanoparticles: Implications for drug and gene delivery. FASEB J 2002; 16: 1217–1226
  • Peitz M, Pfannkuche K, Rajewsky K, Edenhofer F. Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: A tool for efficient genetic engineering of mammalian genomes. PNAS 2002; 99: 4489–4494
  • Stern M, Ulirich K, Geddes DM, Alton EWFW. Poly(d,l-lactide-co-glycolide)/DNA microspheres to facilitate prolonged transgene expression in airway epithelium in vitro, ex vivo and in vivo. Gene Ther 2003; 10: 1282–1288
  • Zalba G, San Jose G, Beaumont FJ, Fortuno MA, Fortuno A, Diez J. Polymorphisms and promoter overactivity of the p22(phox) gene in vascular smooth muscle cells from spontaneously hypertensive rats. Circ Res 2001; 88(2)217–222
  • Zanta MA, Belguise-Valladier P, Behr JP. Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci USA 1999; 96: 91–96

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.