Establishment of a canine model of pulmonary arterial hypertension induced by dehydromonocrotaline and ultrasonographic study of right ventricular remodeling

References

• Holmes D, Corr M, Thomas G, Harbinson M, Campbell M, Spiers P, Bell D. Protective effects of intermedin/adrenomedullin-2 in a cellular model of human pulmonary arterial hypertension. Peptides. 2020;126:170267. doi:10.1016/j.peptides.2020.170267.
   PubMed Web of Science ®Google Scholar
• Agarwal S, Harter ZJ, Krishnamachary B, Chen L, Nguyen T, Voelkel NF, Nk D. Sugen–morphine model of pulmonary arterial hypertension. Pulm Circ. 2020; 10(1):2045894019898376. doi:10.1177/2045894019898376.
   Google Scholar
• Suslonova OV, Smirnova SL, Roshchevskaya IM. Cardiac body surface potentials in rats with experimental pulmonary hypertension during ventricular depolarization. Bull Exp Biol Med. 2016; 162(1):7–9. doi:10.1007/s10517-016-3531-y.
   PubMed Web of Science ®Google Scholar
• Wang XM, Shi K, Li JJ, Chen TT, Guo YH, Liu YL, Yang YF, Yang S. Effects of angiotensin II intervention on MMP-2, MMP-9, TIMP-1, and collagen expression in rats with pulmonary hypertension. Genet Mol Res. 2015; 14(1):1707–17. doi:10.4238/2015.March.6.17.
   PubMed Web of Science ®Google Scholar
• de Lima-Seolin BG, Hennemann MM, Fernandes RO, Colombo R, Bonetto JHP, Teixeira RB, Khaper N, Godoy AEG, Litvin IE, Sander da Rosa Araujo A, et al. Bucindolol attenuates the vascular remodeling of pulmonary arteries by modulating the expression of the endothelin-1 a receptor in rats with pulmonary arterial hypertension. Biomed Pharmacother. 2018;99:704–14. doi:10.1016/j.biopha.2018.01.127.
   PubMed Web of Science ®Google Scholar
• Rafikova O, Al Ghouleh I, Rafikov R. Focus on early events: pathogenesis of pulmonary arterial hypertension development. Antioxid Redox Signal. 2019; 31(13):933–53. doi:10.1089/ars.2018.7673.
   PubMed Web of Science ®Google Scholar
• Zimmer A, Teixeira RB, Constantin RL, Campos-Carraro C, Aparicio Cordero EA, Ortiz VD, Donatti L, Gonzalez E, Bahr AC, Visioli F, et al. The progression of pulmonary arterial hypertension induced by monocrotaline is characterized by lung nitrosative and oxidative stress, and impaired pulmonary artery reactivity. Eur J Pharmacol. 2021;891:173699. doi:10.1016/j.ejphar.2020.173699.
   PubMed Web of Science ®Google Scholar
• Tian L, Wu D, Dasgupta A, Chen KH, Mewburn J, Potus F, Lima PDA, Hong Z, Zhao YY, Hindmarch CCT, et al. Epigenetic metabolic reprogramming of right ventricular fibroblasts in pulmonary arterial hypertension: a pyruvate dehydrogenase kinase-dependent shift in mitochondrial metabolism promotes right ventricular fibrosis. Circ Res. 2020; 126(12):1723–45. doi:10.1161/CIRCRESAHA.120.316443.
   PubMed Web of Science ®Google Scholar
• Yang L, Zhang L, Chen S, Li M, Long Y, Li W, Jin Q, Guan L, Zhou D, Ge J. Efficacy of interatrial shunt devices: an opening window to acute pulmonary hypertensive crisis and chronic pulmonary arterial hypertension. J Thromb Thrombolysis. 2022; 54(1):123–31. doi:10.1007/s11239-022-02635-3.
   PubMed Web of Science ®Google Scholar
• Constantine A, Dimopoulos K. Pulmonary artery denervation for pulmonary arterial hypertension. Trends Cardiovasc Med. 2021; 31(4):252–60. doi:10.1016/j.tcm.2020.04.005.
   PubMed Web of Science ®Google Scholar
• Miller D, Farah MG, Liner A, Fox K, Schluchter M, Bd H. The relation between quantitative right ventricular ejection fraction and indices of tricuspid annular motion and myocardial performance. J Am Soc Echocardiogr. 2004; 17(5):443–47. doi:10.1016/j.echo.2004.01.010.
   PubMed Web of Science ®Google Scholar
• Kasprzak JD, Huttin O, Wierzbowska-Drabik K, Selton-Suty C. Imaging the right heart-pulmonary circulation unit: the role of ultrasound. Heart Fail Clin. 2018; 14(3):361–76. doi:10.1016/j.hfc.2018.03.003.
   PubMed Web of Science ®Google Scholar
• Chuwa T, Rodeheffer RJ. New index of combined systolic and diastolic myocardial performance: a simple and reproducible measure of cardiac function—a study in normals and dilated cardiomyopathy. J Cardiol. 1995;26(35):357–66. PMID: 8558414.
   PubMedGoogle Scholar
• Friesen RM, Schäfer M, Jone PN, et al. Myocardial Perfusion Reserve Index in Children with Kawasaki Disease. J Magn Reson Imaging. 2018;48(1):132–39. doi:10.1002/jmri.25922.
   PubMed Web of Science ®Google Scholar
• Rudski LG, Lai WW, Afilalo J, Hua L, Handschumacher MD, Chandrasekaran K, Solomon SD, Louie EK, Nb S. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography: endorsed by the European association of echocardiography, a registered branch of the European society of cardiology, and the Canadian society of echocardiography. J Am Soc Echocardiogr. 2010; 23(7):685–713. doi:10.1016/j.echo.2010.05.010.
   PubMed Web of Science ®Google Scholar
• Lin ACW, Seale H, Hamilton-Craig C, Morris NR, Strugnell W. Quantification of biventricular strain and assessment of ventriculo-ventricular interaction in pulmonary arterial hypertension using exercise cardiac magnetic resonance imaging and myocardial feature tracking. J Magn Reson Imaging. 2019; 49(5):1427–36. doi:10.1002/jmri.26517.
   PubMed Web of Science ®Google Scholar
• Mansell DS, Bruno VD, Sammut E, Chiribiri A, Johnson T, Khaliulin I, Lopez DB, Gill HS, Fraser KH, Murphy M, et al. Acute regional changes in myocardial strain may predict ventricular remodelling after myocardial infarction in a large animal model. Sci Rep. 2021; 11(1):18322. doi:10.1038/s41598-021-97834-y.
   PubMedGoogle Scholar
• Li Y, Xie M, Wang X, Lu Q, Fu M. Right ventricular regional and global systolic function is diminished in patients with pulmonary arterial hypertension: a 2-dimensional ultrasound speckle tracking echocardiography study. Int J Cardiovasc Imaging. 2013; 29(3):545–51. doi:10.1007/s10554-012-0114-5.
   PubMed Web of Science ®Google Scholar
• Li AL, Zhai ZG, Zhai YN, Xie WM, Wan J, Tao XC. The value of speckle-tracking echocardiography in identifying right heart dysfunction in patients with chronic thromboembolic pulmonary hypertension. Int J Cardiovasc Imaging. 2018; 34(12):1895–904. doi:10.1007/s10554-018-1423-0.
   PubMed Web of Science ®Google Scholar