Advanced search
Publication Cover
Materials Technology
Advanced Performance Materials
Volume 39, 2024 - Issue 1
Submit an article Journal homepage
121
Views
0
CrossRef citations to date
0
Altmetric
Research Article

A type of brain-targeting nano-formulation and its anti-tumour effect in paediatric brain tumour cells

Xin Tiana Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, China;b Department of Hematology and Oncology, Children’s Medical Center, Hunan ProvincialView further author information
,
Taoxiang Shia Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, ChinaView further author information
,
Shiyang Fua Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, ChinaView further author information
,
Zheda Liua Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, ChinaView further author information
,
Yalan Youa Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, China;b Department of Hematology and Oncology, Children’s Medical Center, Hunan ProvincialView further author information
,
Keke Chena Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, China;b Department of Hematology and Oncology, Children’s Medical Center, Hunan ProvincialView further author information
,
Anqi Yaoa Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, China;b Department of Hematology and Oncology, Children’s Medical Center, Hunan ProvincialView further author information
,
Chengguang Zhua Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, China;b Department of Hematology and Oncology, Children’s Medical Center, Hunan ProvincialView further author information
,
Minhui Zenga Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, China;b Department of Hematology and Oncology, Children’s Medical Center, Hunan ProvincialView further author information
,
Wenfang Tanga Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, China;b Department of Hematology and Oncology, Children’s Medical Center, Hunan ProvincialView further author information
,
Xiaojun Taoa Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, ChinaCorrespondence[email protected]
View further author information
&
Xiangling Hea Department of Pediatric Hematology and Oncology, Children’s Medical Center of Hunan Provincial People’s Hospital of The First Affiliated Hospital (X.T., Y.Y., K.C., A.Y., C.Z., M.Z., X.H.); and School of Medicine (T.S., S.F., Z.L., W.T., X.T.), Hunan Normal University, Changsha 410081, China;b Department of Hematology and Oncology, Children’s Medical Center, Hunan ProvincialCorrespondence[email protected]
View further author information
 show all
Article: 2352675 | Received 01 Feb 2024, Accepted 26 Apr 2024, Published online: 13 May 2024

References

  • Malbari F. Pediatric Neuro-Oncology. Neurol Clin. 2021 Aug;39(3):829–14. doi: 10.1016/j.ncl.2021.04.005.
  • Jalali R, Goda JS. Proton beam therapy in pediatric brain tumor patients: improved radiation delivery techniques improve neurocognitive outcomes. Neuro Oncol. 2019;21(7):830–831. doi: 10.1093/neuonc/noz085
  • Packer RJ, Gajjar A, Vezina G, et al. Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma. J Clin Oncol. 2006;24(25):4202–4208. doi: 10.1200/JCO.2006.06.4980
  • Wisoff JH, Sanford RA, Heier LA, et al. Primary neurosurgery for pediatric low-grade gliomas: a prospective multi–institutional study from the Children’s Oncology Group. Neurosurgery. 2011;68(6):1548–1555; discussion 54-5. 10.1227/NEU.0b013e318214a66e
  • Fang FY, Rosenblum JS, Ho WS, et al. New developments in the pathogenesis, therapeutic targeting, and treatment of pediatric medulloblastoma. Cancers (Basel). 2022;14(9):2285. doi: 10.3390/cancers14092285
  • Langen UH, Ayloo S, Gu C. Development and cell biology of the blood-brain barrier. Annu Rev Cell Dev Biol. 2019;35(1):591–613. doi: 10.1146/annurev-cellbio-100617-062608
  • Power EA, Rechberger JS, Gupta S, et al. Drug delivery across the blood-brain barrier for the treatment of pediatric brain tumors - an update. Adv Drug Delivery Rev. 2022;185:114303. doi: 10.1016/j.addr.2022.114303
  • Jin G, Jin M, Yin X, et al. A comparative study on the effect of docetaxel-albumin nanoparticles and docetaxel-loaded PEG-albumin nanoparticles against non-small cell lung cancer. Int J Oncol. 2015;47(5):1945–1953. doi: 10.3892/ijo.2015.3174
  • Ibrahim M, Shimizu T, Ando H, et al. Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice. JControlled Release. 2023;354:260–267. doi: 10.1016/j.jconrel.2023.01.012
  • Dobrovolskaia MA, Aggarwal P, Hall JB, et al. Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution. Mol Pharmaceutics. 2008;5(4):487–495. doi: 10.1021/mp800032f
  • Alexis F, Pridgen E, Molnar LK, et al. Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol Pharmaceutics. 2008;5(4):505–515. doi: 10.1021/mp800051m
  • Bertrand N, Grenier P, Mahmoudi M, et al. Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics. Nat Commun. 2017;8(1):777. doi: 10.1038/s41467-017-00600-w
  • Kreuter J, Shamenkov D, Petrov V, et al. Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier. J Drug Targeting. 2002;10(4):317–325. doi: 10.1080/10611860290031877
  • Burkhart A, Andresen TL, Aigner A, et al. Transfection of primary brain capillary endothelial cells for protein synthesis and secretion of recombinant erythropoietin: a strategy to enable protein delivery to the brain. Cell Mol Life Sci. 2017;74(13):2467–2485. doi: 10.1007/s00018-017-2501-5
  • Wilson B, Samanta MK, Santhi K, et al. Targeted delivery of tacrine into the brain with polysorbate 80-coated poly(n-butylcyanoacrylate) nanoparticles. Eur J Pharm Biopharm. 2008;70(1):75–84. doi: 10.1016/j.ejpb.2008.03.009
  • Zhang N, Yan F, Liang X, et al. Localized delivery of curcumin into brain with polysorbate 80-modified cerasomes by ultrasound-targeted microbubble destruction for improved Parkinson’s disease therapy. Theranostics. 2018;8(8):2264–2277. doi: 10.7150/thno.23734
  • Pavlov R, Romanova E, Kuznetsov D, et al. The formation of morphologically stable lipid nanocarriers for glioma therapy. Int J Mol Sci. 2023;24(4):3632. doi: 10.3390/ijms24043632
  • Jain A, Jain A, Garg NK, et al. Surface engineered polymeric nanocarriers mediate the delivery of transferrin-methotrexate conjugates for an improved understanding of brain cancer. Acta Biomaterialia. 2015;24:140–151. doi: 10.1016/j.actbio.2015.06.027
  • Vanbilloen WJF, Rechberger JS, Anderson JB, et al. Nanoparticle strategies to improve the delivery of anticancer drugs across the blood–brain barrier to treat brain tumors. Pharmaceutics. 2023;15(7):1804. doi: 10.3390/pharmaceutics15071804
  • Hill BT. Vinflunine, a second generation novel vinca alkaloid with a distinctive pharmacological profile, now in clinical development and prospects for future mitotic blockers. CPD. 2001;7(13):1199–1212. doi: 10.2174/1381612013397456
  • Golpayegani MR, Akramipour R, Gheini S, et al. Sensitive determination of vincristine in plasma of children with leukaemia using vortex-assisted dispersive liquid-liquid microextraction based on hydrophobic deep eutectic solvent. RSC Adv. 2022;12(6):3611–3617. doi: 10.1039/D1RA07981F
  • Ruoslahti E. Drug targeting to specific vascular sites. Drug Discovery Today. 2002;7(22):1138–1143. doi: 10.1016/S1359-6446(02)02501-1
  • Mazzone M, Bergers G. Regulation of blood and lymphatic vessels by immune cells in tumors and metastasis. Annu Rev Physiol. 2019;81(1):535–560. doi: 10.1146/annurev-physiol-020518-114721
  • Obireddy SR, Lai WF. Preparation and characterization of 2-hydroxyethyl starch microparticles for co-delivery of multiple bioactive agents. Drug Delivery. 2021;28(1):1562–1568. doi: 10.1080/10717544.2021.1955043
  • Fu X, Rehman U, Wei L, et al. Silver-dendrimer nanocomposite as emerging therapeutics in anti-bacteria and beyond. Drug resistance updates: reviews and commentaries in antimicrobial and anticancer chemotherapy. Drug Resist Updat. 2023;68:100935. doi: 10.1016/j.drup.2023.100935
  • Cheng X, Pei X, Xie W, et al. pH-triggered size-tunable silver nanoparticles: targeted aggregation for effective bacterial infection therapy. Small. 2022;18(22):e2200915. doi: 10.1002/smll.202200915
  • Lv S, Sylvestre M, Song K, et al. Development of D-melittin polymeric nanoparticles for anti-cancer treatment. Biomaterials. 2021;277:121076. doi: 10.1016/j.biomaterials.2021.121076
  • Gandhi S, Shende P. Cyclodextrins-modified metallic nanoparticles for effective cancer therapy. JControlled Release. 2021;339:41–50. doi: 10.1016/j.jconrel.2021.09.025
  • Tang W, Wan S, Yang Z, et al. Tumor origin detection with tissue-specific miRNA and DNA methylation markers. Bioinformatics (Oxford, England). 2018;34(3):398–406. doi: 10.1093/bioinformatics/btx622
  • Arkaban H, Barani M, Akbarizadeh MR, et al. Polyacrylic acid nanoplatforms: antimicrobial, tissue engineering, and cancer theranostic applications. Polymers. 2022;14(6):1259. doi: 10.3390/polym14061259
  • Tao X, Xie Y, Zhang Q, et al. Cholesterol-modified amino-pullulan nanoparticles as a drug carrier: comparative study of cholesterol-modified carboxyethyl pullulan and pullulan nanoparticles. Nanomaterials (Basel). 2016;6(9):165. doi: 10.3390/nano6090165
  • Tao X, Zhang Q, Ling K, et al. Effect of pullulan nanoparticle surface charges on HSA complexation and drug release behavior of HSA-bound nanoparticles. PLOS ONE. 2012;7(11):e49304. doi: 10.1371/journal.pone.0049304
  • Castelletto V, Hamley IW. Self assembly of a model amphiphilic phenylalanine peptide/polyethylene glycol block copolymer in aqueous solution. Biophys Chem. 2009;141(2–3):169–174. doi: 10.1016/j.bpc.2009.01.008
  • Constantin M, Bucatariu S, Sacarescu L, et al. Pullulan derivative with cationic and hydrophobic moieties as an appropriate macromolecule in the synthesis of nanoparticles for drug delivery. Int j biol macromol. 2020;164:4487–4498. doi: 10.1016/j.ijbiomac.2020.09.064
  • Tao X, Tao T, Wen Y, et al. Novel delivery of mitoxantrone with hydrophobically modified pullulan nanoparticles to inhibit bladder cancer cell and the effect of nano-drug size on inhibition efficiency. Nanoscale Res Lett. 2018;13(1):345. doi: 10.1186/s11671-018-2769-x
  • Yuan L, Cao Y, Luo Q, et al. Pullulan-based nanoparticle-HSA complex formation and drug release influenced by surface charge. Nanoscale Res Lett. 2018;13(1):317. doi: 10.1186/s11671-018-2729-5
  • Chauhan VP, Stylianopoulos T, Martin JD, et al. Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner. Nature Nanotechnol. 2012;7(6):383–388. doi: 10.1038/nnano.2012.45
  • Roy S, Bag N, Bardhan S, et al. Recent progress in NIR-II fluorescence imaging-guided drug delivery for cancer theranostics. Adv Drug Delivery Rev. 2023;197:114821. doi: 10.1016/j.addr.2023.114821
  • Egloff-Juras C, Bezdetnaya L, Dolivet G, et al. NIR fluorescence-guided tumor surgery: new strategies for the use of indocyanine green. Int J Nanomed. 2019;14:7823–7838. doi: 10.2147/IJN.S207486
  • Dai Y, Su J, Wu K, et al. Multifunctional thermosensitive liposomes based on natural phase-change material: near-infrared light-triggered drug release and multimodal imaging-guided cancer combination therapy. ACS Appl Mater Interfaces. 2019;11(11):10540–10553. doi: 10.1021/acsami.8b22748
  • Iannone M, Cosco D, Cilurzo F, et al. A novel animal model to evaluate the ability of a drug delivery system to promote the passage through the BBB. Neurosci lett. 2010;469(1):93–96. doi: 10.1016/j.neulet.2009.11.051
  • Wilson B, Samanta MK, Santhi K, et al. Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer’s disease. Brain Res. 2008;1200:159–168. doi: 10.1016/j.brainres.2008.01.039
  • Chen H, Chen H, Liu L, et al. The study of improved controlled release of vincristine sulfate from collagen-chitosan complex film. Artif Cells Blood Substitutes Immobilization Biotechnol. 2008;36(4):372–385. doi: 10.1080/10731190802239057
  • Wang X, Song Y, Su Y, et al. Are PEGylated liposomes better than conventional liposomes? A special case for vincristine. Drug Delivery. 2016;23(4):1092–1100. doi: 10.3109/10717544.2015.1027015
  • Vincristine liposomal–INEX: lipid-encapsulated vincristine, onco TCS, transmembrane carrier system–vincristine, vincacine, vincristine sulfate liposomes for injection, VSLI. Drugs In R&D. 2004;5(2):119–123. doi: 10.2165/00126839-200405020-00012
  • Zhang W, Mehta A, Tong Z, et al. Development of polymeric nanoparticles for blood-brain barrier transfer-strategies and challenges. Adv Sci (Weinheim, Baden-Wurttemberg, Germany). 2021;8(10):2003937. doi: 10.1002/advs.202003937
  • Dong X, Wang W, Qu H, et al. Targeted delivery of doxorubicin and vincristine to lymph cancer: evaluation of novel nanostructured lipid carriers in vitro and in vivo. Drug Delivery. 2016;23(4):1374–1378. doi: 10.3109/10717544.2015.1041580

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.