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Redox Report
Communications in Free Radical Research
Volume 28, 2023 - Issue 1
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Research Article

Glutathione metabolism rewiring protects renal tubule cells against cisplatin-induced apoptosis and ferroptosis

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References

  • Hoste EAJ, Kellum JA, Selby NM, et al. Global epidemiology and outcomes of acute kidney injury. Nat Rev Nephrol. 2018;14(10):607–625.
  • Zuk A, Bonventre JV. Acute kidney injury. Annu Rev Med. 2016;67:293–307.
  • Ozkok A, Edelstein CL. Pathophysiology of cisplatin-induced acute kidney injury. Biomed Res Int. 2014;2014:967826.
  • van der Vorst M, Neefjes ECW, Toffoli EC, et al. Incidence and risk factors for acute kidney injury in head and neck cancer patients treated with concurrent chemoradiation with high-dose cisplatin. BMC Cancer. 2019;19(1):1066.
  • Arany I, Safirstein RL. Cisplatin nephrotoxicity. Semin Nephrol. 2003;23(5):460–464.
  • Deng JS, Jiang WP, Chen CC, et al. Cordyceps cicadae mycelia ameliorate cisplatin-induced acute kidney injury by suppressing the TLR4/NF-κB/MAPK and activating the HO-1/Nrf2 and sirt-1/AMPK pathways in mice. Oxid Med Cell Longev. 2020;2020:7912763.
  • Ma Q, Xu Y, Tang L, et al. Astragalus polysaccharide attenuates cisplatin-induced acute kidney injury by suppressing oxidative damage and mitochondrial dysfunction. Biomed Res Int. 2020;2020:2851349.
  • Tan RZ, Wang C, Deng C, et al. Quercetin protects against cisplatin-induced acute kidney injury by inhibiting mincle/Syk/NF-κB signaling maintained macrophage inflammation. P Phytother Res. 2020;34(1):139–152.
  • Gan B. Mitochondrial regulation of ferroptosis. J Cell Biol. 2021;220(9):e202105043.
  • Wang Y, Zheng L, Shang W, et al. Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer. Cell Death Differ. 2022. doi:10.1038/s41418-022-01008-w.
  • Hu Z, Zhang H, Yi B, et al. VDR activation attenuate cisplatin induced AKI by inhibiting ferroptosis. Cell Death Dis. 2020;11(1):73.
  • Guo J, Xu B, Han Q, et al. Ferroptosis: a novel anti-tumor action for cisplatin. Cancer Res Treat. 2018;50(2):445–460.
  • Manohar S, Leung N. Cisplatin nephrotoxicity: a review of the literature. J Nephrol. 2018;31(1):15–25.
  • Belavgeni A, Meyer C, Stumpf J, et al. Ferroptosis and necroptosis in the kidney. Cell Chem Biol. 2020;27(4):448–462.
  • Linkermann A, Chen G, Dong G, et al. Regulated cell death in AKI. J Am Soc Nephrol. 2014;25(12):2689–2701.
  • Sreekumar PG, Ferrington DA, Kannan R. Glutathione metabolism and the novel role of mitochondrial GSH in retinal degeneration. Antioxidants (Basel, Switzerland). 2021;10(5).
  • Sies H. Glutathione and its role in cellular functions. Free Radic Biol Med. 1999;27(9-10):916–921.
  • Zhao Y, Denner L, Haidacher SJ, et al. Comprehensive analysis of the mouse renal cortex using two-dimensional HPLC-tandem mass spectrometry. Proteome Sci. 2008;6:15.
  • Wu G, Fang YZ, Yang S, et al. Glutathione metabolism and its implications for health. J Nutr. 2004;134(3):489–492.
  • Doke T, Susztak K. The multifaceted role of kidney tubule mitochondrial dysfunction in kidney disease development. Trends Cell Biol. 2022: S0962–S8924. (22)00084-8.
  • Liu J, Yang DC, Zhang J, et al. A novel ReAprotective strategy: upregulation of PD-L1 mitigates cisplatin-induced acute kidney injury. Int J Mol Sci. 2021;22(24):13304.
  • Kurdi M, Sivakumaran V, Duhé RJ, et al. Depletion of cellular glutathione modulates LIF-induced JAK1-STAT3 signaling in cardiac myocytes. Int J Biochem Cell Biol. 2012;44(12):2106–2115.
  • Wu PF, Zhang Z, Wang F, et al. Natural compounds from traditional medicinal herbs in the treatment of cerebral ischemia/reperfusion injury. Acta Pharmacol Sin. 2010;31(12):1523–1531.
  • Khan MA, Nag P, Grivei A, et al. Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells. Cell Death Dis. 2022;13(2):104.
  • Chen C, Cai C, Lin H, et al. Baicalein protects renal tubular epithelial cells against hypoxia-reoxygenation injury. Ren Fail. 2018;40(1):603–610.
  • He L, Wei Q, Liu J, et al. AKI on CKD: heightened injury, suppressed repair, and the underlying mechanisms. Kidney Int. 2017;92(5):1071–1083.
  • Tchounwou PB, Dasari S, Noubissi FK, et al. Advances in our understanding of the molecular mechanisms of action of cisplatin in cancer therapy. J Exp Pharmacol. 2021;13:303–328.
  • Jiang X, Stockwell BR, Conrad M. Ferroptosis: mechanisms,: biology and role in disease. NatRev Mol Cell Biol. 2021;22(4):266–282.
  • Clark AJ, Parikh SM. Mitochondrial metabolism in acute kidney injury. Semin Nephrol. 2020;40(2):101–113.
  • Ursini F, Maiorino M. Lipid peroxidation and ferroptosis: the role of GSH and GPx4. Free Radic Biol Med; 2020;152:175–185.
  • Zhang L, Lu P, Guo X, et al. Inhibition of JAK2/STAT3 signaling pathway protects mice from the DDP-induced acute kidney injury in lung cancer. Inflamm Res. 2019;68(9):751–760.
  • Li HD, Meng XM, Huang C, et al. Application of herbal traditional Chinese medicine in the treatment of acute kidney injury. Front Pharmacol. 2019;10:376.
  • Liu H, Dong Y, Gao Y, et al. The fascinating effects of baicalein on cancer: a review. Int J Mol Sci. 2016;17(10):1681.