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Original Research

The effect of epilepsy and antiseizure medications on cardiac autonomic functions in children with epilepsy

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Pages 393-401 | Received 13 Dec 2023, Accepted 07 Feb 2024, Published online: 19 Feb 2024

References

  • Hauser WA. Incidence and prevalence. In: VNGel J Pedley T, editors. Epilepsy: a comprehensive textbook. Philadelphia: Lippincott-Raven; 1997. p. 47–57.
  • Kandil MR, Ahmed WA, Sayed AM, et al. Pattern of epilepsy in childhood and adolescence: a hospital-based study. African J Neurol Scien. 2007;26(1):33–45. doi: 10.4314/ajns.v26i1.7592
  • Kwan P, Arzimanoglou A, Berg AT, et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc task force of the ILAE Commission on Therapeutic Strategies. Epilepsia. 2010;51(6):1069–1077. doi: 10.1111/j.1528-1167.2009.02397.x
  • Marshall DW, Westmoreland BF, Sharbrough FW. Ictal tachycardia during temporal lobe seizures. Mayo Clin Proc. 1983;58(7):443–446.
  • Novak V, Reeves AL, Novak P, et al. Time-frequency mapping of R-R interval during complex partial seizures of temporal lobe origin. J Auton Nerv Syst. 1999;77(2–3):195–202. doi: 10.1016/S0165-1838(99)00044-2
  • Britton JW, Ghearing GR, Benarroch EE, et al. The ictal bradycardia syndrome: localization and lateralization. Epilepsia. 2006;47(4):737–744. doi: 10.1111/j.1528-1167.2006.00509.x
  • Toth V, Hejjel L, Fogarasi A, et al. Periictal heart rate variability analysis suggests long-term postictal autonomic disturbance in epilepsy. Eur J Neurol. 2010;17(6):780–787. doi: 10.1111/j.1468-1331.2009.02939.x
  • Surges R, Scott CA, Walker MC. Enhanced QT shortening and persistent tachycardia after generalized seizures. Neurology. 2010;74(5):421–426. doi: 10.1212/WNL.0b013e3181ccc706
  • Chen W, Guo CL, Zhang PS, et al. Heart rate changes in partial seizures: analysis of influencing factors among refractory patients. BMC neurol. 2014;14(1):135. doi: 10.1186/1471-2377-14-135
  • Devinsky O, Perrine K, Theodore WH. Interictal autonomic nervous system function in patients with epilepsy. Epilepsia. 1994;35(1):199–204. doi: 10.1111/j.1528-1157.1994.tb02933.x
  • Massetani R, Strata G, Galli R, et al. Alteration of cardiac function in patients with temporal lobe epilepsy: different roles of EEG-ECG monitoring and spectral analysis of RR variability. Epilepsia. 1997;38(3):363–369. doi: 10.1111/j.1528-1157.1997.tb01129.x
  • Tomson T, Ericson M, Ihrman C, et al. Heart rate variability in patients with epilepsy. Epilepsy Res. 1998;30(1):77–83. doi: 10.1016/S0920-1211(97)00094-6
  • Persson H, Ericson M, Tomson T. Carbamazepine affects autonomic cardiac control in patients with newly diagnosed epilepsy. Epilepsy Res. 2003;57(1):69–75. doi: 10.1016/j.eplepsyres.2003.10.012
  • Sathyaprabha TN, Satishchandra P, Netravathi K, et al. Cardiac autonomic dysfunctions in chronic refractory epilepsy. Epilepsy Res. 2006;72(1):49–56. doi: 10.1016/j.eplepsyres.2006.07.011
  • Mukherjee S, Tripathi M, Chandra PS, et al. Cardiovascular autonomic functions in well-controlled and intractable partial epilepsies. Epilepsy Res. 2009;85(2–3):261–269. doi: 10.1016/j.eplepsyres.2009.03.021
  • Lotufo PA, Valiengo L, Benseñor IM, et al. A systematic review and meta-analysis of heart rate variability in epilepsy and antiepileptic drugs. Epilepsia. 2012;53(2):272–282. doi: 10.1111/j.1528-1167.2011.03361.x
  • Critchley HD, Corfield DR, Chandler MP, et al. Cerebral correlates of autonomic cardiovascular arousal: a functional neuroimaging investigation in humans. J Physiol. 2000;523 Pt 1(Pt 1):259–270.
  • Blumhardt LD, Smith PE, Owen L. Electrocardiographic accompaniments of temporal lobe epileptic seizures. Lancet. 1986;1(8489):1051–1056. doi: 10.1016/S0140-6736(86)91328-0
  • Eggleston KS, Olin BD, Fisher RS. Ictal tachycardia: the head-heart connection. Seizure. 2014;23(7):496–505. doi: 10.1016/j.seizure.2014.02.012
  • Lamberts RJ, Blom MT, Novy J, et al. Increased prevalence of ECG markers for sudden cardiac arrest in refractory epilepsy. J Neurol Neurosurg Psychiatry. 2015;86(3):309–313. doi: 10.1136/jnnp-2014-307772
  • Feldman AE, Gidal BE. Qtc prolongation by antiepileptic drugs and the risk of torsade de pointes in patients with epilepsy. Epilepsy Behav. 2013;26(3):421–426. doi: 10.1016/j.yebeh.2012.09.021
  • van der Lende M, Surges R, Sander JW, et al. Cardiac arrhythmias during or after epileptic seizures. J Neurol Neurosurg Psychiatry. 2016;87(1):69–74. doi: 10.1016/j.autneu.2015.07.066
  • Ansakorpi H, Korpelainen JT, Huikuri HV, et al. Heart rate dynamics in refractory and well controlled temporal lobe epilepsy. J Neurol Neurosurg Psychiatry. 2002;72(1):26–30. doi: 10.1136/jnnp.72.1.26
  • Harnod T, Yang CC, Hsin YL, et al. Heart rate variability in children with refractory generalized epilepsy. Seizure. 2008;17(4):297–301. doi: 10.1016/j.seizure.2007.09.002
  • Faustmann PM, Ganz RE. Central cardio-autonomic disorganization in interictal states of epilepsy detected by phase space analysis. Int J Neurosci. 1994;78(1–2):43–47. doi: 10.3109/00207459408986044
  • Sivakumar SS, Namath AG, Tuxhorn IE, et al. Decreased heart rate and enhanced sinus arrhythmia during interictal sleep demonstrate autonomic imbalance in generalized epilepsy. J Neurophysiol. 2016;115(4):1988–1999. doi: 10.1152/jn.01120.2015
  • Hallioglu O, Okuyaz C, Mert E, et al. Effects of antiepileptic drug therapy on heart rate variability in children with epilepsy. Epilepsy Res. 2008;79(1):49–54. doi: 10.1016/j.eplepsyres.2007.12.020
  • El-Rashidy OF, Shatla RH, Youssef OI, et al. Cardiac autonomic balance in children with epilepsy: value of antiepileptic drugs. Pediatr Neurol. 2015;52(4):419–423. doi: 10.1016/j.pediatrneurol.2014.11.018
  • Danielsson C, Azarbayjani F, Sköld AC, et al. Polytherapy with hERG-blocking antiepileptic drugs: increased risk for embryonic cardiac arrhythmia and teratogenicity. Birth Defects Res A Clin Mol Terato. 2007;79(8):595–603. doi: 10.1002/bdra.20378
  • Labrecque J, Coté MA, Vincent P. Carbamazepine-induced atrioventricular block. Am J Psychiatr. 1992;149(4):572–573.
  • Johnson CD, Rivera H, Jiménez JE. Carbamazepine-induced sinus node dysfunction. P R Health Sci J. 1997;16(1):45–49.
  • Margerison JH, Corsellis JA. Epilepsy and the temporal lobes. A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes. Brain. 1966;89(3):499–530. doi: 10.1093/brain/89.3.499
  • Lathers CM, PL S. Autonomic dysfunction in epilepsy: characterization of autonomic cardiac neural discharge associated with pentylenetetrazol-induced epileptogenic activity. Epilepsia. 1982;23(6):633–647. doi: 10.1111/j.1528-1157.1982.tb05079.x
  • Babb TL, Brown WJ, Pretorius J, et al. Temporal lobe volumetric cell densities in temporal lobe epilepsy. Epilepsia. 1984;25(6):729–740. doi: 10.1111/j.1528-1157.1984.tb03484.x
  • Weil S, Arnold S, Eisensehr I, et al. Heart rate increase in otherwise subclinical seizures is different in temporal versus extratemporal seizure onset: support for temporal lobe autonomic influence. Epileptic Disord. 2005;7(3):199–204.
  • Wong CH, Bleasel A, Wen L, et al. The topography and significance of extratemporal hypometabolism in refractory mesial temporal lobe epilepsy examined by FDG-PET. Epilepsia. 2010;51(8):1365–1373. doi: 10.1111/j.1528-1167.2010.02552.x
  • Baumgartner C, Koren J, Britto-Arias M, et al. Epidemiology and pathophysiology of autonomic seizures: a systematic review. Clin Auton Res. 2019;29(2):137–150. doi: 10.1007/s10286-019-00596-x
  • Kloster R, Engelskjøn T. Sudden unexpected death in epilepsy (SUDEP): a clinical perspective and a search for risk factors. J Neurol Neurosurg Psychiatry. 1999;67(4):439–444. doi: 10.1136/jnnp.67.4.439
  • Scheffer IE, Berkovic S, Capovilla G, et al. ILAE classification of the epilepsies: position paper of the ILAE Commission for classification and terminology. Epilepsia. 2017;58(4):512–521. doi: 10.1111/epi.13709
  • Ewing DJ, Martyn CN, Young RJ, et al. The value of cardiovascular autonomic function tests: 10 years experience in diabetes. Diabetes Care. 1985;8(5):491–498. doi: 10.2337/diacare.8.5.491
  • Oppenheimer SM, Gelb A, Girvin JP, et al. Cardiovascular effects of human insular cortex stimulation. Neurology. 1992;42(9):1727–1732. doi: 10.1212/WNL.42.9.1727
  • Isojärvi JI, Ansakorpi H, Suominen K, et al. Interictal cardiovascular autonomic responses in patients with epilepsy. Epilepsia. 1998;39(4):420–426. doi: 10.1111/j.1528-1157.1998.tb01394.x
  • Kuo CC. A common anticonvulsant binding site for phenytoin, carbamazepine, and lamotrigine in neuronal Na+ channels. Mol Pharmacol. 1998;54(4):712–721.
  • Traccis S, Monaco F, Sechi GP, et al. Long-term therapy with carbamazepine: effects on nerve conduction velocity. Eur Neurol. 1983;22(6):410–416. doi: 10.1159/000115594
  • Zanatta G, Sula A, Miles AJ, et al. Valproic acid interactions with the NavMs voltage-gated sodium channel. Proc Natl Acad Sci U S A. 2019;116(52):26549–26554. doi: 10.1073/pnas.1909696116
  • Guldiken B, Rémi J, Noachtar S. Cardiovascular adverse effects of phenytoin. J Neurol. 2016;263(5):861–870. doi: 10.1007/s00415-015-7967-1
  • Aurlien D, Larsen JP, Gjerstad L, et al. Increased risk of sudden unexpected death in epilepsy in females using lamotrigine: a nested, case-control study. Epilepsia. 2012;53(2):258–266. doi: 10.1111/j.1528-1167.2011.03334.x
  • Beydoun A, D’Souza J, Hebert D, et al. Lacosamide: pharmacology, mechanisms of action and pooled efficacy and safety data in partial-onset seizures. Expert Rev Neurother. 2009;9(1):33–42. doi: 10.1586/14737175.9.1.33

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