Original animal model of lumbar disc degeneration

References

• Qaseem A, Wilt TJ, McLean RM, et al. Noninvasive treatments for acute, subacute, and chronic low back pain: a clinical practice guideline from the American College of physicians. Ann internal med. 2017;166(7):514–15.
   PubMed Web of Science ®Google Scholar
• Sakai D. Future perspectives of cell-based therapy for intervertebral disc disease. Eur Spine J. 2008;17(4):452–458.
   PubMedGoogle Scholar
• Stoyanov JV, Gantenbein-Ritter B, Bertolo A, et al. Role of hypoxia and growth and differentiation factor-5 on differentiation of human mesenchymal stem cells towards intervertebral nucleus pulposus-like cells. Eur Cell Mater. 2011;21(533):e47.
   Google Scholar
• Chou R. In the clinic low back pain. Ann internal med. 2014;160(11): ITC6-ITC1.
   Web of Science ®Google Scholar
• Rivera ED, Meakin JR, Holsgrove TP. In-vitro models of disc degeneration–A review of methods and clinical relevance. J Biomech. 2022;142:111260.
   PubMed Web of Science ®Google Scholar
• Hoogendoorn RJ, Helder MN, Kroeze RJ, et al. Reproducible long-term disc degeneration in a large animal model. Spine. 2008;33(9):949–954.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Wang H, Li Z, et al. Lumbar disk degeneration in female patients with and without ovariectomy: a case-control study. World Neurosurg. 2021;156:68–75.
   PubMed Web of Science ®Google Scholar
• Tian T, Wang H, Li Z, et al. Intervertebral disc degeneration induced by needle puncture and ovariectomy: a rat coccygeal model. Bio Med Res Int. 2021;2021:1–7.
   Google Scholar
• Alini M, Eisenstein SM, Ito K, et al. Are animal models useful for studying human disc disorders/degeneration? Eur Spine J. 2008;17(1):2–19.
   PubMed Web of Science ®Google Scholar
• Masuda K, Aota Y, Muehleman C, et al. A novel rabbit model of mild, reproducible disc degeneration by an anulus needle puncture: correlation between the degree of disc injury and radiological and histological appearances of disc degeneration. Spine. 2005;30(1):5–14.
   PubMed Web of Science ®Google Scholar
• Thompson JP, Pearce RH, Schechter MT, et al. Preliminary evaluation of a scheme for grading the gross morphology of the human intervertebral disc. Spine. 1990;15(5):411–415.
   PubMed Web of Science ®Google Scholar
• Lai A, Gansau J, Gullbrand SE, et al. Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: an initiative of the ORS spine section. JOR Spine. 2021;4(2):e1150.
   PubMedGoogle Scholar
• Berlemann U, Gries NC, Moore RJ. The relationship between height, shape and histological changes in early degeneration of the lower lumbar discs. Eur Spine J. 1998;7(3):212–217.
   PubMedGoogle Scholar
• Elmounedi N, Bahloul W, Guidara AR, et al. Establishment of an animal model of disc degeneration by intradiscal injection of monosodium iodoacetate. World Neurosurg. 2023.
   PubMed Web of Science ®Google Scholar
• Elmounedi N, Bahloul W, Turki M, et al. Impact of needle size on the onset and the progression of disc degeneration in rats. Pain Physician. 2022;25(6):509–517.
   PubMed Web of Science ®Google Scholar
• Keorochana G, Johnson JS, Taghavi CE, et al. The effect of needle size inducing degeneration in the rat caudal disc: evaluation using radiograph, magnetic resonance imaging, histology, and immunohistochemistry. Spine J. 2010;10(11):1014–1023.
   PubMed Web of Science ®Google Scholar
• Xiao ZF, He JB, Su GY, et al. Osteoporosis of the vertebra and osteochondral remodeling of the endplate causes intervertebral disc degeneration in ovariectomized mice. Arthritis Research & Therapy. 2018;20(1):1–15.
   PubMedGoogle Scholar
• Özcan-Ekşi EE, Turgut VU, Küçüksüleymanoğlu D, et al. Obesity could be associated with poor paraspinal muscle quality at upper lumbar levels and degenerated spine at lower lumbar levels: is this a domino effect? J Clin Neurosci. 2021;94:120–127.
   PubMed Web of Science ®Google Scholar
• Daly C, Ghosh P, Jenkin G, et al. A review of animal models of intervertebral disc degeneration: pathophysiology, regeneration, and translation to the clinic. Bio Med Res Int. 2016;2016:5952165.
   Google Scholar
• Singh K, Masuda K, An HS. Animal models for human disc degeneration. Spine J. 2005;5(6):S267–279.
   Google Scholar
• Elliott DM, Sarver JJ. Young investigator award winner: validation of the mouse and rat disc as mechanical models of the human lumbar disc. Spine. 2004;29(7):713–722.
   PubMed Web of Science ®Google Scholar
• Deng M, Griffith JF, Zhu XM, et al. Effect of ovariectomy on contrast agent diffusion into lumbar intervertebral disc: a dynamic contrast-enhanced MRI study in female rats. Magn Reson Imaging. 2012;30(5):683–688.
   PubMed Web of Science ®Google Scholar
• Jin L, Balian G, Li XJ. Animal models for disc degeneration-an update. Histol Histopathol. 2018;33(6):543.
   PubMed Web of Science ®Google Scholar
• Jin LY, Song XX, Li XF. The role of estrogen in intervertebral disc degeneration. Steroids. 2020;154:108549.
   PubMed Web of Science ®Google Scholar
• de Schepper EI, Damen J, van Meurs JB, et al. The association between lumbar disc degeneration and low back pain: the influence of age, gender, and individual radiographic features. Spine. 2010;35(5):531–536.
   PubMed Web of Science ®Google Scholar
• Wang YXJ, Griffith JF. Effect of menopause on lumbar disk degeneration: potential etiology. Radiology. 2010;257(2):318–320.
   PubMed Web of Science ®Google Scholar
• Baron YM, Brincat MP, Galea R, et al. Intervertebral disc height in treated and untreated overweight post-menopausal women. Hum Reprod. 2005;20(12):3566–3570.
   PubMed Web of Science ®Google Scholar
• Yang SD, Yang DL, Sun YP, et al. 17β-estradiol protects against apoptosis induced by interleukin-1β in rat nucleus pulposus cells by down-regulating MMP-3 and MMP-13. Apoptosis. 2015;20(3):348–357.
   PubMed Web of Science ®Google Scholar
• Guo HT, Yang SD, Zhang F, et al. 17βEstradiol protects against interleukin 1β induced apoptosis in rat nucleus pulposus cells via the mTOR/caspase3 pathway. Mol Med Rep. 2019;20(2):1523–1530.
   PubMed Web of Science ®Google Scholar
• Jin LY, Lv ZD, Wang K, et al. Estradiol alleviates intervertebral disc degeneration through modulating the antioxidant enzymes and inhibiting autophagy in the model of menopause rats. Oxidative Medicine and Cellular Longevity. 2018;2018.
   Web of Science ®Google Scholar
• Imada K, Matsui H, Tsuji H. Oophorectomy predisposes to degenerative spondylolisthesis. J Bone Joint Surg Br Vol. 1995;77(1):126–130.
   PubMedGoogle Scholar
• Norcross JP, Lester GE, Weinhold P, et al. An in vivo model of degenerative disc disease. J Orthop Res. 2003;21(1):183–188.
   PubMed Web of Science ®Google Scholar
• Kang JD. Does a needle puncture into the annulus fibrosus cause disc degeneration? Spine J. 2010;10(12):1106–1107.
   PubMed Web of Science ®Google Scholar
• Nassr A, Lee JY, Bashir RS, et al. Does incorrect level needle localization during anterior cervical discectomy and fusion lead to accelerated disc degeneration? Spine. 2009;34(2):189–192.
   PubMed Web of Science ®Google Scholar
• Özcan-Ekşi EE, Ekşi MŞ, Akçal MA. Severe lumbar intervertebral disc degeneration is associated with modic changes and fatty infiltration in the paraspinal muscles at all lumbar levels, except for L1-L2: a cross-sectional analysis of 50 symptomatic women and 50 age-matched symptomatic men. World Neurosurg. 2019;122: e1069-e1R077.
   PubMed Web of Science ®Google Scholar
• Teichtahl AJ, Urquhart DM, Wang Y, et al. Lumbar disc degeneration is associated with modic change and high paraspinal fat content–a 3.0 T magnetic resonance imaging study. BMC Musculoskelet Disord. 2016;17(1):1–7.
   PubMedGoogle Scholar