A cross-sectional investigation of factors influencing mpox vaccine hesitancy for students in Southwest China

References

• Kugelman JR, Johnston SC, Mulembakani PM, Kisalu N, Lee MS, Koroleva G, McCarthy SE, Gestole MC, Wolfe ND, Fair JN, et al. Genomic variability of monkeypox virus among humans, Democratic Republic of the Congo. Emerg Infect Dis. 2014;20(2):232–9. doi:10.3201/eid2002.130118.
   PubMed Web of Science ®Google Scholar
• Yang X, Hu C, Yang X, Yang X, Hu X, Wang X, Liu C, Yuan Y, Du S, Wang PG, et al. Evaluation and comparison of immune responses induced by two mpox mRNA vaccine candidates in mice. J Med Virol. 2023;95(10):e29140. doi:10.1002/jmv.29140.
   PubMed Web of Science ®Google Scholar
• Kaler J, Hussain A, Flores G, Kheiri S, Desrosiers D. Monkeypox: a comprehensive review of transmission, pathogenesis, and manifestation. Cureus. 2022;14:e26531. doi:10.7759/cureus.26531.
   PubMed Web of Science ®Google Scholar
• Lum FM, Torres-Ruesta A, Tay MZ, Lin RTP, Lye DC, Rénia L, Ng LFP. Monkeypox: disease epidemiology, host immunity and clinical interventions. Nat Rev Immunol. 2022;22(10):597–613. doi:10.1038/s41577-022-00775-4.
   PubMed Web of Science ®Google Scholar
• Rizk JG, Lippi G, Henry BM, Forthal DN, Rizk Y. Prevention and treatment of monkeypox. Drugs. 2022;82(9):957–63. doi:10.1007/s40265-022-01742-y.
   PubMed Web of Science ®Google Scholar
• Rodriguez-Morales AJ, Lopardo G. Monkeypox: another sexually transmitted infection? Pathogens (Basel, Switzerland). 2022;11(7):713. doi:10.3390/pathogens11070713.
   PubMed Web of Science ®Google Scholar
• Thornhill JP, Barkati S, Walmsley S, Rockstroh J, Antinori A, Harrison LB, Palich R, Nori A, Reeves I, Habibi MS, et al. Monkeypox virus infection in humans across 16 Countries — April–June 2022. N Engl J Med. 2022;387(8):679–91. doi:10.1056/NEJMoa2207323.
   PubMed Web of Science ®Google Scholar
• WHO. 2022-23 Mpox (Monkeypox) outbreak: global trends; [Accessed 2023 Aug 29]. https://worldhealthorg.shinyapps.io/mpx_global/.
   Google Scholar
• Kozlov M. Monkeypox outbreaks: 4 key questions researchers have. Nature. 2022;606(7913):238–9. doi:10.1038/d41586-022-01493-6.
   PubMed Web of Science ®Google Scholar
• Di Giulio DB, Eckburg PB. Human monkeypox: an emerging zoonosis. Lancet Infect Dis. 2004;4(1):15–25. doi:10.1016/s1473-3099(03)00856-9.
   PubMed Web of Science ®Google Scholar
• Petersen BW, Harms TJ, Reynolds MG, Harrison LH. Use of vaccinia virus smallpox vaccine in laboratory and health care personnel at risk for occupational exposure to orthopoxviruses — recommendations of the advisory committee on immunization practices (ACIP), 2015. Morb Mortal Wkly Rep. 2016;65(10):257–62. doi:10.15585/mmwr.mm6510a2.
   PubMed Web of Science ®Google Scholar
• Rao AK, Petersen BW, Whitehill F, Razeq JH, Isaacs SN, Merchlinsky MJ, Campos-Outcalt D, Morgan RL, Damon I, Sánchez PJ, et al. Use of JYNNEOS (smallpox and monkeypox vaccine, live, nonreplicating) for preexposure vaccination of persons at risk for occupational exposure to orthopoxviruses: recommendations of the advisory committee on immunization practices — United States, 2022. Morb Mortal Wkly Rep. 2022;71(22):734–42. doi:10.15585/mmwr.mm7122e1.
   PubMed Web of Science ®Google Scholar
• Vivancos R, Anderson C, Blomquist P, Balasegaram S, Bell A, Bishop L, Brown CS, Chow Y, Edeghere O, Florence I, et al. Community transmission of monkeypox in the United Kingdom, April to May 2022. Eurosurveillance. 2022;27(22). doi:10.2807/1560-7917.Es.2022.27.22.2200422.
   Web of Science ®Google Scholar
• Yang X, Yang X, Du S, Hu C, Yang X, Wang X, Hu X, Rcheulishvili N, Wang PG, Lin J. A subunit vaccine candidate composed of mpox virus A29, LM1R, A35R, and B6R elicits robust immune response in mice. Vaccines. 2023;11(9):11. doi:10.3390/vaccines11091420.
   Web of Science ®Google Scholar
• MacDonald NE. Vaccine hesitancy: definition, scope and determinants. Vaccine. 2015;33(34):4161–4. doi:10.1016/j.vaccine.2015.04.036.
   PubMed Web of Science ®Google Scholar
• Organization WH. Ten threats to global health in 2019; 2019. https://www.who.int/vietnam/news/feature-stories/detail/ten-threats-to-global-health-in-2019.
   Google Scholar
• Prevention CCfDCa. Monkeypox outbreak surveillance for August 2023; 2023. https://www.chinacdc.cn/jkzt/crb/zl/szkb_13037/gwjszl_13092/202309/t20230908_269405.html.
   Google Scholar
• M L, X H, Chang W. A study on the spatial and temporal evolution of AIDS distribution in China and its influencing factors. Chinese J Health Stat. 2020;37:116–20.
   Google Scholar
• Qian S, Guo W, Wang L. Spatial analysis of the aggregated AIDS epidemic in China based on geographic information systems. Chinese J Health Stat. 2014;31:1064–7.
   Google Scholar
• Cong L, Ono-Kihara M, Xu G, Ma Q, Pan X, Zhang D, Homma T, Kihara M. The characterisation of sexual behaviour in Chinese male university students who have sex with other men: a cross-sectional study. BMC Public Health. 2008;8(1):250. doi:10.1186/1471-2458-8-250.
   PubMedGoogle Scholar
• Yang Z, Chen W, Jin M, Chen W, Zhou X, Wang H, Chen L, Jiang T. Analysis of homosexual behavior characteristics and influencing factors of male college students in Zhejiang Province. Medicine. 2021;100(30):e26746. doi:10.1097/md.0000000000026746.
   PubMed Web of Science ®Google Scholar
• Fan S, Li P, Hu Y, Gong H, Yu M, Ding Y, Luo Z, Wu G, Ouyang L, Zou H, et al. Geosocial networking smartphone app use and high-risk sexual behaviors among men who have sex with men attending university in China: cross-sectional study. MIR Public Health Surveill. 2022;8(3):e31033. doi:10.2196/31033.
   PubMedGoogle Scholar
• Lulli LG, Baldassarre A, Mucci N, Arcangeli G. Prevention, risk exposure, and knowledge of monkeypox in occupational settings: a scoping review. Trop Med Infect Dis. 2022;7(10):276. doi:10.3390/tropicalmed7100276.
   PubMedGoogle Scholar
• Kumar N, Ahmed F, Raza MS, Rajpoot PL, Rehman W, Khatri SA, Mohammed M, Muhammad S, Ahmad R. Monkeypox cross-sectional survey of knowledge, attitudes, practices, and willingness to vaccinate among university students in Pakistan. Vaccines. 2022;11(1):11. doi:10.3390/vaccines11010097.
   Web of Science ®Google Scholar
• Betancort-Plata C, Lopez-Delgado L, Jaén-Sanchez N, Tosco-Nuñez T, Suarez-Hormiga L, Lavilla-Salgado C, Pisos-Álamo E, Hernández-Betancor A, Hernández-Cabrera M, Carranza-Rodríguez C, et al. Monkeypox and HIV in the Canary Islands: a different pattern in a mobile population. Trop Med Infect Dis. 2022;7(10):318. doi:10.3390/tropicalmed7100318.
   PubMedGoogle Scholar
• Ibrahim AM, Zaghamir DEF. Knowledge and attitudes towards mpox and effect of intervention among college of applied medical sciences students. Libyan J Med. 2023;18(1):2222448. doi:10.1080/19932820.2023.2222448.
   PubMed Web of Science ®Google Scholar
• Li Y, Peng X, Fu L, Wang B, Sun Y, Chen Y, Lin Y-F, Wu X, Liu Q, Gao Y, et al. Monkeypox awareness and low vaccination hesitancy among men who have sex with men in China. J Med Virol. 2023;95(2):e28567. doi:10.1002/jmv.28567.
   PubMed Web of Science ®Google Scholar
• Li M, Zheng Y, Luo Y, Ren J, Jiang L, Tang J, Yu X, Luo D, Fan D, Chen Y, et al. Hesitancy toward COVID-19 vaccines among medical students in Southwest China: a cross-sectional study. Hum Vaccin Immunother. 2021;17(11):4021–7. doi:10.1080/21645515.2021.1957648.
   PubMed Web of Science ®Google Scholar
• Prevention CCfDCa. Surveillance of monkeypox outbreaks in 2023; 2023. https://www.chinacdc.cn/jkzt/crb/zl/szkb_13037/gnyq/202310/t20231016_270134.html.
   Google Scholar
• Isidro J, Borges V, Pinto M, Sobral D, Santos JD, Nunes A, Mixão V, Ferreira R, Santos D, Duarte S, et al. Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus. Nat Med. 2022;28(8):1569–72. doi:10.1038/s41591-022-01907-y.
   PubMed Web of Science ®Google Scholar
• Lv S, Lu J, Li X. Progress in research on monkeypox virus and its vaccine. Chinese J Biol. 2022;35:1409–13. doi:10.13200/j.cnki.cjb.003776.
   Google Scholar
• Wang Y, Li L, Zhou W. The status quo of the coming out of young men who have sex with men and their self-identity and the analysis of the related factors in Mianyang city. Chinese J Hum Sex. 2019;28:149–53.
   Google Scholar
• Liang Y, Li J, Li T. Analysis of behavioral characteristics of AIDS high-risk populations and HIV infection risk. Chinese J Dermatovenereol. 2013;27:1026–8.
   Google Scholar
• Lin HR, Zhang YL, Zeng Y, Li JY, Peng CM, Xu JQ. Analysis and discussion on the epidemiological investigation of 16 cases of monkeypox. China Trop Med . 2023 Nov 15;24(1):107–110. doi:10.13604/j.cnki.46-1064/r.2024.01.20.
   Google Scholar
• Schäfer M, Stark B, Werner AM, Mülder LM, Heller S, Reichel JL, Schwab L, Rigotti T, Beutel ME, Simon P, et al. Determinants of university students’ COVID-19 vaccination intentions and behavior. Sci Rep. 2022;12(1):18067. doi:10.1038/s41598-022-23044-9.
   PubMed Web of Science ®Google Scholar
• Tavolacci MP, Dechelotte P, Ladner J. COVID-19 vaccine acceptance, hesitancy, and resistancy among university students in France. Vaccines. 2021;9(6). doi:10.3390/vaccines9060654.
   Web of Science ®Google Scholar
• Hong J, Pan B, Jiang HJ, Zhang QM, Xu XW, Jiang H, Ye J-E, Cui Y, Yan X-J, Zhai X-F, et al. The willingness of Chinese healthcare workers to receive monkeypox vaccine and its independent predictors: a cross-sectional survey. J Med Virol. 2023;95(1):e28294. doi:10.1002/jmv.28294.
   PubMed Web of Science ®Google Scholar
• Feng Y, Zhang Y, Liu S, Guo M, Huang H, Guo C, Wang W, Zhang W, Tang H, Wan Y, et al. Unexpectedly higher levels of anti-orthopoxvirus neutralizing antibodies are observed among gay men than general adult population. BMC Med. 2023;21(1):183. doi:10.1186/s12916-023-02872-0.
   PubMed Web of Science ®Google Scholar
• Reyes-Urueña J, D’Ambrosio A, Croci R, Bluemel B, Cenciarelli O, Pharris A, Dukers-Muijrers N, Nutland W, Niaupari S, Badran J, et al. High monkeypox vaccine acceptance among male users of smartphone-based online gay-dating apps in Europe, 30 July to 12 August 2022. Eurosurveillance. 2022;27(42). doi:10.2807/1560-7917.Es.2022.27.42.2200757.
   Web of Science ®Google Scholar
• Mose A, Haile K, Timerga A, Delcea C. COVID-19 vaccine hesitancy among medical and health science students attending Wolkite University in Ethiopia. PLoS One. 2022;17(1):e0263081. doi:10.1371/journal.pone.0263081.
   PubMed Web of Science ®Google Scholar
• Zou H, Huang Y, Chen T, Zhang L. Influenza vaccine hesitancy and influencing factors among university students in China: a multicenter cross-sectional survey. Ann Med. 2023;55(1):2195206. doi:10.1080/07853890.2023.2195206.
   PubMed Web of Science ®Google Scholar
• Huang Y, Chen C, Wang L, Wu H, Chen T, Zhang L. HPV vaccine hesitancy and influencing factors among university students in China: a cross-sectional survey based on the 3Cs model. Int J Envir Res Pub Health. 2022;19(21):14025. doi:10.3390/ijerph192114025.
   PubMed Web of Science ®Google Scholar
• Chen Y, Zhang MX, Lin XQ, Wu H, Tung TH, Zhu JS. COVID-19 vaccine hesitancy between teachers and students in a college, a cross-sectional study in China. Hum Vaccin Immunother. 2022;18(5):2082171. doi:10.1080/21645515.2022.2082171.
   PubMed Web of Science ®Google Scholar
• Silva J, Bratberg J, Lemay V. COVID-19 and influenza vaccine hesitancy among college students. J Am Pharm Assoc. 2021;61(6):709–14.e1. doi:10.1016/j.japh.2021.05.009.
   Google Scholar
• Jiao K, Xu Y, Huang S, Zhang Y, Zhou J, Li Y, Xiao Y, Ma W, He L, Ren X, et al. Mpox risk perception and associated factors among Chinese young men who have sex with men: results from a large cross-sectional survey. J Med Virol. 2023;95(8):e29057. doi:10.1002/jmv.29057.
   PubMed Web of Science ®Google Scholar
• Dong C, Yu Z, Zhao Y, Ma X. Knowledge and vaccination intention of monkeypox in China’s general population: a cross-sectional online survey. Travel Med Infect Dis. 2023;52:102533. doi:10.1016/j.tmaid.2022.102533.
   PubMed Web of Science ®Google Scholar
• Sallam M, Al-Mahzoum K, Dardas LA, Al-Tammemi AB, Al-Majali L, Al-Naimat H, Jardaneh L, AlHadidi F, Al-Salahat K, Al-Ajlouni E, et al. Knowledge of human monkeypox and its relation to conspiracy beliefs among students in Jordanian health schools: filling the knowledge gap on emerging zoonotic viruses. Med (Kaunas, Lithuania). 2022;58(7):924. doi:10.3390/medicina58070924.
   PubMed Web of Science ®Google Scholar
• Takayanagi IJ, Cardoso MR, Costa SF, Araya ME, Machado CM. Attitudes of health care workers to influenza vaccination: why are they not vaccinated? Am J Infect Control. 2007;35(1):56–61. doi:10.1016/j.ajic.2006.06.002.
   PubMed Web of Science ®Google Scholar
• Sanchez AM, Busse K, MacKinnon K, Henk L, MacKinnon GE, Brown J, Mauermann, S, Dobrowski, T, Jungmann, J, Bultman, J Singh, S. Collective action: the medical college of Wisconsin COVID-19 vaccination program. WMJ. 2021;120:305–8.
   PubMedGoogle Scholar
• Dratva J, Wagner A, Zysset A, Volken T. To vaccinate or not to vaccinate—this is the question among Swiss university students. Int J Envir Res Pub Health. 2021;18(17):18. doi:10.3390/ijerph18179210.
   Web of Science ®Google Scholar
• Ye M, Giri M. Prevalence and correlates of HIV infection among men who have sex with men: a multi-provincial cross-sectional study in the southwest of China. HIV/AIDS (Auckland, NZ). 2018;10:167–75. doi:10.2147/hiv.S176826.
   PubMed Web of Science ®Google Scholar
• He J, Yuan L, Wu C. Temporal⁃spatial distribution of AIDS epidemic in China. Chin J Dis Control Prev. 2022;26:541–6. doi:10.16462/j.cnki.zhjbkz.2022.05.009.
   Google Scholar