Advanced search
Publication Cover
Human Vaccines & Immunotherapeutics Volume 20, 2024 - Issue 1
Submit an article Journal homepage
770
Views
0
CrossRef citations to date
0
Altmetric
HPV

Distribution of HPV types among women with HPV-related diseases and exploration of lineages and variants of HPV 52 and 58 among HPV-infected patients in China: A systematic literature review

Meng Wanga Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, WHO Collaborating Center for Standardization and Evaluation of Biologicals, State Key Laboratory of Drug Regulatory Science, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products and NMPA Key Laboratory for Quality Research and Evaluation of Biological Products, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, ChinaView further author information
,
Haoyu Lianga Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, WHO Collaborating Center for Standardization and Evaluation of Biologicals, State Key Laboratory of Drug Regulatory Science, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products and NMPA Key Laboratory for Quality Research and Evaluation of Biological Products, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, ChinaView further author information
,
Yue Yanb Merck Research Laboratories (MRL) Global Medical Affairs, MSD China, Shanghai, ChinaView further author information
,
Rui Bianb Merck Research Laboratories (MRL) Global Medical Affairs, MSD China, Shanghai, ChinaView further author information
,
Weijin Huanga Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, WHO Collaborating Center for Standardization and Evaluation of Biologicals, State Key Laboratory of Drug Regulatory Science, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products and NMPA Key Laboratory for Quality Research and Evaluation of Biological Products, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, ChinaView further author information
,
Xingxing Zhangb Merck Research Laboratories (MRL) Global Medical Affairs, MSD China, Shanghai, ChinaCorrespondence[email protected]
View further author information
&
Jianhui Niea Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, WHO Collaborating Center for Standardization and Evaluation of Biologicals, State Key Laboratory of Drug Regulatory Science, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products and NMPA Key Laboratory for Quality Research and Evaluation of Biological Products, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, ChinaCorrespondence[email protected]
View further author information
 show all
Article: 2343192 | Received 29 Dec 2023, Accepted 11 Apr 2024, Published online: 14 May 2024

References

  • Human papillomavirus vaccines: WHO position paper (2022 update). 2022.
  • de Martel C, Georges D, Bray F, Ferlay J, Clifford GM. Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis. Lancet Global Health. 2020;8(2):180–26. doi:10.1016/S2214-109X(19)30488-7.
  • Kombe Kombe AJ, Li B, Zahid A, Mengist HM, Bounda GA, Zhou Y. Epidemiology and Burden of Human Papillomavirus and Related Diseases, Molecular Pathogenesis, and Vaccine Evaluation. Front Public Health. 2021;8:552028. doi:10.3389/fpubh.2020.552028.
  • Cao W, Chen HD, Yu YW, Li N, Chen WQ. Changing profiles of cancer burden worldwide and in China: a secondary analysis of the global cancer statistics 2020. Chin Med J. 2021;134(7):783–91. doi:10.1097/CM9.0000000000001474.
  • Chen W, Zheng R, Baade PD, Zhang S, Zeng H, Bray F, Jemal A, Yu XQ, He J. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66(2):115–32. doi:10.3322/caac.21338.
  • Bruni L, Albero G, Serrano B, Mena M, Collado J, Gómez D, Muñoz J, Bosch F, De Sanjosé S. Human papillomavirus and related diseases in the world. Summary Report 10 March 2023. ICO/IARC Information Centre on HPV and Cancer (HPV Information Centre); 2023.
  • Zhu X, Wang Y, Lv Z, Su J. Prevalence and genotype distribution of high-risk HPV infection among women in Beijing, China. J Med Virol. 2021;93(8):5103–9. doi:10.1002/jmv.27013.
  • Zhu C, Diao W, Wang Q, Sui L. Analysis of HPV genotype distribution in 475 cases of cervical squamous intraepithelial lesions in Shanghai. Fudan J (Med Ed). 2016;43:447–52.
  • Yu Y, Liu H. Meta-analysis of distribution of cervical human papillomavirus types in women of Liaoning region. Chin Mod Doctor. 2021;59:108–13.
  • Zu Y, Ou Z, Wu D, Liu W, Liu L, Wu D, Zhao Y, Ren P, Zhang Y, Li W, et al. Genetic characteristics of human papillomavirus type 16, 18, 52 and 58 in southern China. Genomics. 2021;113(6):3895–906. doi:10.1016/j.ygeno.2021.09.006.
  • Xiang Y, Wang Q, Zhang B. Distribution of different subtypes of HPV in patients with high-grade cervical lesions. J Bengbu Med Coll. 2020;45:1407–9, 13.
  • Organization WH. Global strategy to accelerate the elimination of cervical cancer as a public health problem [EB/OL]. 2020 Sept 6. https://www.who.int/publications/i/item/9789240014107.
  • Organization WH. HPV vaccine global market study [EB/OL]. 2022 Sept 8. https://www.who.int/publications/m/item/who‑hpv‑vaccine‑global‑market‑study‑april‑2022.2022.
  • Bruni L, Saura-Lázaro A, Montoliu A, Brotons M, Alemany L, Diallo MS, Afsar OZ, LaMontagne DS, Mosina L, Contreras M, et al. HPV vaccination introduction worldwide and WHO and UNICEF estimates of national HPV immunization coverage 2010–2019. Prev Med. 2021;144:106399. doi:10.1016/j.ypmed.2020.106399.
  • Song Y, Liu X, Yin Z, Yu W, Cao L, Cao L, Ye J, Li L, Wu J. Human papillomavirus vaccine coverage among the 9–45-year-old female population of China in 2018–2020. Chin J Vaccines Immunization. 2021;27(5):570–5.
  • Yang Z, Zhang C, Luo P, Sun F, Mei B. Genetic diversity and functional implication of the long control region in human papillomavirus types 52, 58, and 16 from central China. Infect Genet Evol. 2023;112:105447. doi:10.1016/j.meegid.2023.105447.
  • Zhang C, Park JS, Grce M, Hibbitts S, Palefsky JM, Konno R, Smith-McCune KK, Giovannelli L, Chu T-Y, Picconi MA, et al. Geographical distribution and risk association of human papillomavirusgenotype 52–variant lineages. J Infect Dis. 2014;210(10):1600–4. doi:10.1093/infdis/jiu310.
  • Bernard HU. The clinical importance of the nomenclature, evolution and taxonomy of human papillomaviruses. J Clin Virol. 2005;32(Suppl 1):S1–6. doi:10.1016/j.jcv.2004.10.021.
  • Chen Z, Schiffman M, Herrero R, Desalle R, Anastos K, Segondy M, Sahasrabuddhe VV, Gravitt PE, Hsing AW, Burk RD, et al. Evolution and taxonomic classification of human papillomavirus 16 (HPV16)-related variant genomes: HPV31, HPV33, HPV35, HPV52, HPV58 and HPV67. PLOS ONE. 2011;6(5):e20183. doi:10.1371/journal.pone.0020183.
  • Clifford GM, Tenet V, Georges D, Alemany L, Pavón MA, Chen Z, Yeager M, Cullen M, Boland JF, Bass S, Steinberg M. Human papillomavirus 16 sub-lineage dispersal and cervical cancer risk worldwide: whole viral genome sequences from 7116 HPV16-positive women.Papillomavirus res (Amsterdam.Netherlands.2019;Vol. 7:pp. 67–74.
  • Chen Z, Schiffman M, Herrero R, DeSalle R, Anastos K, Segondy M, Sahasrabuddhe VV, Gravitt PE, Hsing AW, Chan PK, Burk RD, et al. Classification and evolution of human papillomavirus genome variants: Alpha-5 (HPV26, 51, 69, 82), Alpha-6 (HPV30, 53, 56, 66), Alpha-11 (HPV34, 73), Alpha-13 (HPV54) and Alpha-3 (HPV61). Virology. 2018;516:86–101. doi:10.1016/j.virol.2018.01.002.
  • Munn Z, Moola S, Riitano D, Lisy K. The development of a critical appraisal tool for use in systematic reviews addressing questions of prevalence. Int J Health Policy Manag. 2014;3(3):123–8. doi:10.15171/ijhpm.2014.71.
  • Eknoyan G, Levin A, Levin NW. K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Am J Kidney Dis. 2003;42(4 Suppl 3):S1–201. doi:10.1016/S0272-6386(03)00905-3.
  • Schiffman M, Solomon D, Solomon CG. Clinical practice. Cervical-cancer screening with human papillomavirus and cytologic cotesting. N Engl J Med. 2013;369(24):2324–31. doi:10.1056/NEJMcp1210379.
  • Ao M, Zheng D, Wang J, Gu X, Xi M. A retrospective study of cytology and HPV genotypes results of 3229 vaginal intraepithelial neoplasia patients. J Med Virol. 2022;94(2):737–44. doi:10.1002/jmv.27311.
  • Baloch Z, Li Y, Yuan T, Feng Y, Liu Y, Tai W, Liu L, Wang B, Zhang A-M, Wu X, et al. Epidemiologic characterization of human papillomavirus (HPV) infection in various regions of Yunnan Province of China. BMC Infect Dis. 2016;16(1):228. doi:10.1186/s12879-016-1562-7.
  • Cai W, Wang H, Geng J, Xia L, Long X, Wang X. Distribution of HPV infection genotypes in normal cells of the uterine cervix and tissues of squamous cell carcinoma and adenocarcinoma of the uterine cervix. Chin J Clin Exp Path. 2014;30(8):854–7+62.
  • Chen Y. Study on the correlation between human papillomavirus genotypes and cervical lesions in Tianshui area. Chin Primary Health Care. 2013;27:42–4.
  • Chen W, Sun H, Molijn A, Zeng L, Kang L, Jenkins D, Zhang S, Cui J, Wu Z, Pirog E, et al. The variable characteristics of human papillomavirus in squamous cell carcinoma and adenocarcinoma of Cervix in China. J Low Genit Tract Dis. 2018;22(4):355–61. doi:10.1097/LGT.0000000000000408.
  • Chen Z, Zhen H, Huang L. Human papillomavirus infection and genotype distribution in women in. Wuhan: Jianghan University; 2019.
  • Chen G, Zheng P, Gao L, Zhao J, Wang Y, Qin W. Prevalence and genotype distribution of human papillomavirus in women with cervical cancer or cervical intraepithelial neoplasia in Henan province, central China. J Med Virol. 2020;92(12):3743–9. doi:10.1002/jmv.25670.
  • Chen L, Cheng H. HPV18 E7 antibody preparation, application and survey of HPV subtypes in patients with cervical lesions. Hangzhou (China): Zhejiang University; 2020.
  • Cui Y, Zhang P, Lu T, Huang X, Lv S. Human papillomavirus infection status and genotype analysis in women with cervical lesions in Xi’an. Chin J Woman Child Health Res. 2016;27:819–21.
  • Ding X, Liu Z, Su J, Yan D, Sun W, Zeng Z. Human papillomavirus type-specific prevalence in women referred for colposcopic examination in Beijing. J Med Virol. 2014;86(11):1937–43. doi:10.1002/jmv.24044.
  • Fan J, Xue M. Study on the relationship between HPV infection and cervical lesions and related risk factors. Changsha (China): Central South University; 2014.
  • Fan LY, Zhan P, Wang CY, Liu YF. Characteristics of HPV infection among 4 084 gynecological outpatients. J Army Med Univ. 2023;45:335–42.
  • Fang C. Analysis of human papillomavirus infection in 651 patients with squamous cervical cancer. Mod Pract Med. 2018;30:495–7.
  • Gao W, Gao D, Yu X, Xu Y. Distribution of human papillomavirus infection subtypes and its correlation with cervical lesions in Hefei women. J Pract Med. 2019;35:1785–8+93.
  • Gong P, Wang Z, Geng J, Tan X. Comparative study on detection and typing of human papillomavirus (HPV) Infection with microarray using paraffin-embedded specimens from squamous cell carcinoma and cervical precursor lesions. J Nanosci Nanotechnol. 2017;17(2):990–7. doi:10.1166/jnn.2017.12769.
  • Gu X, Long X, Yu Z, Xia S, Geng J. An analytical description of distributions of HPV genotypes patients with cervical precancerous lesions and squamous cell carcinoma in Zhejiang and Jiangsu area. Int J Clin Exp Med. 2017;10:6987–93.
  • He L, He J. Distribution of high-risk HPV types among women in Sichuan province, China: a cross-sectional study. BMC Infect Dis. 2019;19(1):390. doi:10.1186/s12879-019-4038-8.
  • Hou SN, Cheng WG, Lu HM, Li YY, Shen QY, C Y. High-risk HPV genotyping distribution and human papillomavirus E6/E7 expression in different degrees of cervical lesions. Med Lab Sci Clin. 2022;33:25–8,4.
  • Hu W, Fu Y. Clinical analysis of 519 cases of cervical lesions in middle-aged and elderly women without primary prevention of HPV vaccine. Changchun (China): Jilin University; 2021.
  • Hu X, Meng L, Gao Y, Man S, Ma Y, Jin C, Wang B, Ning Y, Li L. Current status of human papillomavirus infection and abnormal cervical cytology in a female medical examination population in Shenzhen. Chin J Epidemiol. 2021;42(7):1205–12. doi:10.3760/cma.j.cn112338-20210106-00007.
  • Huang Y, Zhou HZH. Study on HPV infection in cervical cancer screening population and its relationship with cervical lesions. Kunming (China): Kunming Medical University; 2019.
  • Jin L, Zhang X, Xiao L, Zhang L, Yang H, Zhang L. Analysis of cervical human papillomavirus genotyping in 116441 census women. J Bengbu Med Coll. 2018;43:462–7.
  • Jin R, Yang X, Bao J, Zhang W, Dou R, Yuan D, Jiang L, Yu H. The prevalence and genotype distribution of human papilloma virus in cervical squamous intraepithelial lesion and squamous cell carcinoma in Taizhou, China. Medicine (Baltimore). 2021;100(28):e26593. doi:10.1097/MD.0000000000026593.
  • Li H, Zhang J, Chen Z, Zhou B, Tan Y. Prevalence of human papillomavirus genotypes among women in Hunan province, China. Eur J Obstet Gynecol Reprod Biol. 2013;170(1):202–5. doi:10.1016/j.ejogrb.2013.05.010.
  • Li D, Xiao Z, Chen Y. Epidemiological survey of HPV in cervical cancer patients in a region. lab Med Clin. 2014;11:2423–4.
  • Li K, Yin R, Li Q, Wang D. Analysis of HPV distribution in patients with cervical precancerous lesions in Western China. Medicine (Baltimore). 2017;96(29):e7304. doi:10.1097/MD.0000000000007304.
  • Li K, Yin R, Wang D, Li Q. Human papillomavirus subtypes distribution among 2309 cervical cancer patients in West China. Oncotarget. 2017;8(17):28502–9. doi:10.18632/oncotarget.16093.
  • Li X, Wan X, Zheng F, Zhu H, Zhu X, Yu J. Comparison of human papillomavirus genotype distributions in cervical intraepithelial neoplasia and cervical cancer. Biomed Res (India). 2017;28:2284–9.
  • Yuanyue L, Baloch Z, Yasmeen N, Tao Y, Xiaomei W, Xueshan X. The distribution of human papillomavirus genotypes in cervical cancer and intraepithelial neoplasia lesions among Chinese women in Yunnan Province. J Infect Public Health. 2018;11(1):105–10. doi:10.1016/j.jiph.2017.06.012.
  • Li M, Du X, Lu M, Zhang W, Sun Z, Li L, Ye M, Fan W, Jiang S, Liu A, et al. Prevalence characteristics of single and multiple HPV infections in women with cervical cancer and precancerous lesions in Beijing, China. J Med Virol. 2019;91(3):473–81. doi:10.1002/jmv.25331.
  • Li C, Luo X, Li J. Characterization of HPV infection in women in Xiangxi autonomous prefecture. Jishou (China): Jishou University; 2019.
  • Li R, Yin X. Exploration of HPV distribution characteristics of high-grade cervical lesions and its application value in post-LEEP follow-up. China Med Pharm. 2019;9:85–8.
  • Li G, Liu G. Preliminary investigation on the role of HPV and PLOD2 in the progression of cervical intraepithelial neoplasia. Guangzhou (China): Nanfang Medical University; 2020.
  • Li Y, Wang H, Zhang Y, Jing X, Wu N, Hou Y, Hao C. Correlation between multi-type human papillomavirus infections and viral loads and the cervical pathological grade. Int J Gynaecol Obstet. 2021;152(1):96–102. doi:10.1002/ijgo.13406.
  • XJ L. Analysis of cervical cancer precancerous lesion, cervical cancer and human papillomavirus infection. Zhongguo Wei Sheng Jian Yan. 2023;33:853–7.
  • Liao L, Cheng H, Zeng F, Zhou W, Ding Y. Prevalence and distribution of human papillomavirus genotypes among women with high-grade squamous intraepithelial lesion and invasive cervical cancer in Ganzhou, China. J Clin Lab Anal. 2019;33(3):e22708. doi:10.1002/jcla.22708.
  • Liu Q. Association between different subtypes of HPV infection and cervical lesions. Clin Res Practicev. 2016;1:36–7.
  • Liu J, Zhang X, Luo M, Zhang Y, Wang Q, Zhang J Clinicopathological characteristics of cervical exfoliative cytology-negative genital tract high-risk human papillomavirus-positive patients. J Capital Med Univ. 2018;39(6):858–63.
  • Liu Y, Ang Q, Wu H, Xu J, Chen D, Zhao H, Liu H, Guo X, Gu Y, Qiu H, et al. Prevalence of human papillomavirus genotypes and precancerous cervical lesions in a screening population in Beijing, China: analysis of results from China’s top 3 hospital, 2009–2019. Virol J. 2020;17(1):104. doi:10.1186/s12985-020-01383-1.
  • Liu F, Chang L, Bai T, Liu X, Hu J. Association of human papillomavirus genotype distribution and cervical cytology: a cross-sectional study. Epidemiol Infect. 2021;149:e95. doi:10.1017/S0950268821000741.
  • Long W, Yang Z, Li X, Chen M, Liu J, Zhang Y, Sun X. HPV-16, HPV-58, and HPV-33 are the most carcinogenic HPV genotypes in Southwestern China and their viral loads are associated with severity of premalignant lesions in the cervix. Virol J. 2018;15(1):94. doi:10.1186/s12985-018-1003-x.
  • Ma Q, Hou M, Yang XF. Screening of the genital human papillomavirus infection among 8581 women in the first affiliated hospital of Xi’an Jiaotong university. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2014;36(3):277–82. doi:10.3881/j.issn.1000-503X.2014.03.009.
  • Ma M, Zhu J, Yang Y, Wang X, Jin Y, Zhang J, Wu S. The distribution and pathogenic risk of non-9-valent vaccine covered HPV subtypes in cervical lesions. Cancer Med. 2022;11(6):1542–52. doi:10.1002/cam4.4532.
  • Meng J, Xu X, Lu Y, Fan Z, Cai G. Survey analysis of cervical exfoliative cell HPV infection subtypes among women in Shanghai from 2017 to 2020. J Diagn Concepts Pract. 2021;20:567–72.
  • Ou Y. Clinical analysis of human papillomavirus infection characteristics and relationship with cervical lesions in women in southern. Guangdong: Guangzhou Medical University; 2014.
  • Pang X, Mo L. Study on the relationship between different cervical lesions and HPV infection subtypes. Nanning (China): Guangxi Medical University; 2017.
  • Qin Y. Retrospective cohort study of focused ultrasound in the treatment of high-risk HPV infection with HSIL. Chongqing (China): ChongQing Medical University; 2022.
  • Qiu YT, Zhou JJ, Zhang JY. Epidemiological investigation and analysis of HPV infection and cervical intraepithelial neoplasia in women in pingxiang area. Med Innovation China. 2022;19:79–83.
  • Ren L, Shi Q, Wei Y. The relationship between human papillomavirus genotypes and cervical lesions. Chin Cancer Res Clin. 2016;28:107–11.
  • Shen Y, Gong JM, Li YQ, Gong YM, Lei DM, Cheng GM, Li XF. Epidemiology and genotype distribution of human papillomavirus (HPV) in women of Henan Province, China. Clin Chim Acta. 2013;415:297–301. doi:10.1016/j.cca.2012.11.005.
  • Singh S, Zhou Q, Yu Y, Xu X, Huang X, Zhao J, Han L, Wang K, Sun J, Li F. Distribution of HPV genotypes in Shanghai women. Int J Clin Exp Pathol. 2015;8(9):11901–8.
  • Song L, Lyu Y, Ding L, Li X, Gao W, Wang M, Hao M, Wang Z, Wang J. Prevalence and genotype distribution of high-risk human papillomavirus infection in women with abnormal cervical cytology: A population-based study in Shanxi Province, China. Cancer Manag Res. 2020;12:12583–91.
  • Sun D, Huang J, Geng J, Zhao G, Liu B, Wang C. Comparative analysis of HPV infection types in female genital tract diseases. Mil Med J Southeast China. 2022;24(2):128–32.
  • Tan Y, Xie L, Shi G, Yuan H, Liang J. Screening status and genotype analysis of 3632 human papillomavirus cases. Lab Med Clin. 2021;18:384–7.
  • Tang X, Jones TE, Jiang W, Austin M, He Y, Li L, Tong L, Wang C, Yang K, Yin R, et al. Extended human papillomavirus genotype distribution in cervical intraepithelial neoplasia and cancer: Analysis of 40 352 cases from a large academic gynecologic center in China. J Med Virol. 2023;95(1):e28302. doi:10.1002/jmv.28302.
  • Tao X, Zhang H, Zhang H, Xiao Y, Zhong F, Zhou X, Cong Q, Sui L, Zhao C. The clinical utility of extended high-risk HPV genotyping in risk-stratifying women with L-SIL cytology: A retrospective study of 8726 cases. Cancer Cytopathol. 2022;130(7):542–50. doi:10.1002/cncy.22573.
  • Tung H, Tang Y, Yang L, Huang H, Wu R, Pan Y, Jung S, Lin C, Wang C, Chao A, et al. Human papillomavirus genotype and long-term clinical outcomes of vulvar malignancies. Int J Gynecol Cancer. 2020;30:A75.
  • Wang L, Wu N. The value of TCT, HPV and DNA quantitative cytology in cervical lesions. Dalian (China): Dalian Medical University; 2013.
  • Wang X, Wang L. HPV genotype distribution and value of liquid-based cytology combined with HPV typing test and HPV16 DNA integration status in the screening and management of cervical lesions. Shijiazhuang (China): Hebei Medical University; 2013.
  • Wang H, Xie X. Distribution of HPV infection types in invasive cervical cancer and precancerous lesions in the Yangtze River Delta region of. China: Zhejiang University; 2014.
  • Wang L, Wu B, Li J, Chen L. Prevalence of human papillomavirus and its genotype among 1336 invasive cervical cancer patients in Hunan province, central south China. J Med Virol. 2015;87(3):516–21. doi:10.1002/jmv.24094.
  • Wang Y, Wang S, Shen J, Peng Y, Chen L, Mai R, Zhang G. Genotype distribution of human papillomavirus among women with cervical cytological abnormalities or invasive squamous cell carcinoma in a high-incidence area of esophageal carcinoma in China. Biomed Res Int. 2016;2016:1–6. doi:10.1155/2016/1256384.
  • Wang Z, Li Z, Li J, Wang C, Wang W, Hao M, Zhao C. Prevalence and distribution of HPV genotypes in 1387 women with cervical intraepithelial neoplasia 2/3 in Shanxi Province, China. J Cancer. 2018;9(16):2802–6. doi:10.7150/jca.25614.
  • Wang J, Tang D, Wang J, Zhang Z, Chen Y, Wang K, Zhang X, Ma C. Genotype distribution and prevalence of human papillomavirus among women with cervical cytological abnormalities in Xinjiang, China. Hum Vaccin Immunother. 2019;15(7):1889–96. doi:10.1080/21645515.2019.1578598.
  • Wang WP, An JS, Yao HW, Li N, Zhang YY, Ge L, Song Y, Wang MJ, Yuan GW, Sun YC, et al. Prevalence and attribution of high-risk HPV in different histological types of cervical cancer. Chin J Obstetrics Gynecology. 2019;54(5):293–300.
  • Wang J, Tang D, Wang J, Chen Y, Ma C. Survey on the prevalence and genotype distribution of human papillomavirus in patients with cervical squamous intraepithelial lesions and cervical cancer in Xinjiang. Chin J Hum Sex. 2020;29:35–8.
  • Wang L, He Y. Value of HPV typing test in the diagnosis of cervical lesions. Bengbu (China): Bengbu Medical College; 2020.
  • Wang XL, Sun H, Zhou QH, Chen YE, Fu JH, Li CM, Zhou A. Correlation between different HR-HPV subtypes and the severity of cervical lesions. J Cancer Control Treat. 2022;35(6):549–53.
  • Wu X, Zhao J, Cui X, Li Q, Tao H, Pan Q, Zhang X, Chen W, Li YP, Li RC, et al. [Prevalence of type-specific human papillomavirus infection among 18–45 year-old women from the general population in Liuzhou, Guangxi Zhuang autonomous region: a cross-sectional study]. Chin J Epidemiol. 2017;38(4):467–71. doi:10.3760/cma.j.issn.0254-6450.2017.04.011.
  • Wu Y, Wu X, Lv W, Zhang X, Zheng J. Clinical value of human papillomavirus genotyping in cervical lesions. J Molecular Diagnostics And Therapeutics. 2017;9:416–21.
  • Xiao X, Meng YB, Bai P, Zou J, Zhang Y, Bui Nguyen TM, Xiao J-G, Gao X-M, Wen B-F. Vulvar cancer in China: epidemiological features and risk analysis. J Cancer. 2017;8(15):2950–8. doi:10.7150/jca.20496.
  • Xu XX, Zhou JS, Yuan SH, Yu H, Lou HM. Distribution of HPV genotype in invasive cervical carcinoma and cervical intraepithelial neoplasia in Zhejiang Province, Southeast China: Establishing the baseline for surveillance. Int J Environ Res Public Health. 2015;12(9):10794–805. doi:10.3390/ijerph120910794.
  • Xu X, Feng T, Li D, Lou H, Lan H. Prevalent distribution and survival outcome of HPV infection in patients with early-stage cervical cancer in Hangzhou, China. BMC Infect Dis. 2022;22(1):941. doi:10.1186/s12879-022-07888-0.
  • Xu H, Chen Y, Zhao C, Wang Q, Tang M, Zhang W, Wang Q, Lou R, Liu T, Feng Y, et al. Bethesda system reporting rates, histological follow-up and HPV genotypes distribution of abnormal cytology in Anhui province of China: Analysis of 93,168 cervical liquid-based cytology test reports. Diagn Cytopathol. 2023;51(8):501–10. doi:10.1002/dc.25150.
  • Xue H, Gao H, Zheng J, Chen Y, Chen J, Pan D, Dong B, Sun P. Use of extended HR-HPV genotyping in improving the triage strategy of 2019 ASCCP recommendations in women with positive HR-HPV diagnosis and simultaneous LSIL cytology results. J Cancer. 2021;12(14):4332–40. doi:10.7150/jca.55826.
  • Yan H, Zhao J, Liu DJ, Chen GH. Analysis on human papillomavirus infection in 2 110 patients with cervical cancer in Henan province. Chin J Epidemiol. 2021;42(5):914–7. doi:10.3760/cma.j.cn112338-20200729-00992.
  • Yang H. Study of cervical HPV infection type and its significance in pre-cancer screening of the cervix. Chinese Medical Engineering. 2015;23:174+6.
  • Yang C, Xu Q, Zhang L, Wang J, Tian L, Zhan X. Analysis of 9227 cases of HPV infection status in naturally attending female patients in linyi people’s Hospital. Chin J Cancer Prev Treat. 2020;27:1113–18.
  • Yang T, Zhang W, Tan L, Gao Z, Ma L. Distribution characteristics of HPV subtypes in cervical intraepithelial neoplasia among ethnic minorities in kunming. Medicine And Pharmacy Of Yunnan. 2021;42:476–8.
  • You W, Li S, Du R, Zheng J, Shen A. Epidemiological study of high-risk human papillomavirus infection in subjects with abnormal cytological findings in cervical cancer screening. Exp Ther Med. 2018;15(1):412–8. doi:10.3892/etm.2017.5357.
  • Yu Z, Wang C, Geng J, Fan X, Zhang X, Xia L, Wang H, Long X, Zhao X. Distribution of HPV infection genotypes in cervical normal cells and cervical CIN grade III lesions and squamous cell carcinoma tissues. Maternal And Child Health Care Of China. 2015;30(31):5354–8.
  • Yuan H, Li R, Lv J, Yi G, Sun X, Zhao N, Zhao F, Xu A, Kou Z, Wen H. Epidemiology of human papillomavirus on condyloma acuminatum in Shandong Province, China. Hum Vaccin Immunother. 2023;19(1):2170662. doi:10.1080/21645515.2023.2170662.
  • Zhai Q, Wang X, Yu D, Fan Y, Li X, Ma Y, Meng Y, Li L, First Medical Center of PLA General Hospital. Distribution of high-risk human papillomavirus types and their prognosis in patients with high-grade cervical intraepithelial neoplasia. Zhonghua Yi Yuan Gan Ran Xue Za Zhi. 2021;31(10):1576–80.
  • Zhang ZM, Cui XQ, Li N, Zhang GJ, Zhao YH, Liu RR, Xie Q, Gao B. Human papillomavirus genotypes distribution in patients with cervical intraepithelial neoplasia and microinvasive cancer Chinese. Journal Of Xi’an Jiaotong University (Medical Sciences). 2016;37:697–702.
  • Zhang L, Bi Q, Deng H, Xu J, Chen J, Zhang M, Mu X. Human papillomavirus infections among women with cervical lesions and cervical cancer in Eastern China: genotype-specific prevalence and attribution. BMC Infect Dis. 2017;17(1):107. doi:10.1186/s12879-017-2223-1.
  • Zhang L, Xie F, Zhao D, Jiang L, Peng D, Wang B, et al. Analysis of human papillomavirus infection subtypes in female patients with condyloma acuminatum in Shandong Province. Chin J Hum Sex. 2018;27(9):105–9.
  • Zhang C, Huang C, Zheng X, Pan D. Prevalence of human papillomavirus among Wenzhou women diagnosed with cervical intraepithelial neoplasia and cervical cancer. Infect Agent Cancer. 2018;13(1):37. doi:10.1186/s13027-018-0211-8.
  • Zhang J, Zhang D, Yang Z, Wang X, Wang D. The role of human papillomavirus genotyping for detecting high-grade intraepithelial neoplasia or cancer in HPV-positive women with normal cytology: a study from a hospital in northeastern China. BMC Cancer. 2020;20(1):443. doi:10.1186/s12885-020-06935-w.
  • Zhang L, Wang Q, Zhang H, Xie Y, Sui L, Cong Q. Screening history in vaginal precancer and cancer: A retrospective study of 2131 cases in China. Cancer Manag Res. 2021;13:8855–63. doi:10.2147/CMAR.S335701.
  • Zhang QF, Wan ZQ, Tang JL. Characterization of HPV subtype distribution and analysis of risk factors in patients with cervical squamous intraepithelial lesion and cervical cancer. Mod Pract Med. 2022;34:1052–4+102.
  • Zhang R, Hong G, Liao C, Chen Z, Lin H, Yu L. High-risk human papillomavirus infection in Putian, China: a cross-sectional analysis of 98085 women. Journal Of The College Of Physicians And Surgeons–Pakistan: JCPSP. 2023;33:642–6.
  • Zhao XY, Kong WM, Jiao SM, Song D, Chen J, Shang RT. Prevalence and genotypes of human papilloma virus infection in CIN3 in Beijing, China. Transl Cancer Res. 2020;9(3):1978–84. doi:10.21037/tcr.2020.01.59.
  • Zheng S. Analysis of cervical HPV infection status and its correlation with vaginal microecology in 16324 women. Jinan (China): Shandong University; 2021.
  • Zhi HF, Yang LF, Ge J, Yang XT. The human papillomavirus infection characteristics for patients with cervical intraepithelial neoplasia in Yunnan, China: A sampling survey analysis. Infect Drug Resist. 2022;15:2843–51. doi:10.2147/IDR.S364763.
  • Zhong F, Li Z, Sun Y, Xiao Y, Li J, Zhou X, Cong Q, Sui L, Tao X, Zhao C. HPV genotyping of cervical histologic specimens of 61, 422 patients from the largest women hospital in China. Front Oncol. 2023;13:1161631. doi:10.3389/fonc.2023.1161631.
  • Zhou A, Du Y. Study on cervical cancer screening and influencing factors among rural women with household registration in. Wuhan: Huazhong University of Science and Technology; 2014.
  • Zhou Q, Shi Q, Zhao J, Wang D, Tang Z. Study on the genetic subtype distribution of human papillomavirus infection in patients with squamous and adenocarcinoma of the cervix in Gansu. Health Vocational Education. 2019;37:142–4.
  • Zhou J, Niaz M, Zhou Q, Wang P, Chen W, Li J. Analysis of the current status and influencing factors of HPV infection in cervical cancer patients in western China. Chinese Journal Of Clinical Obstetrics And Gynecology. 2020;21:13–16.
  • Zhou J, Xu H. Analysis of HPV infection status of cervical cancer screening population in wenshan prefecture. Yunnan Province: Baise (China): Yujiang Ethnic College of Medicine; 2020.
  • Zhu L, Guo J, Lv B, Zhang L, Li X. Analysis of the distribution of HPV infection genotypes in normal cervical tissue, cervical squamous cell carcinoma and adenocarcinoma tissue. Chin J Hum Sex. 2017;26:58–61.
  • Zhu C, Wang Y, Mao W, Zhang H, Ma J. Prevalence and distribution of HPV types in genital warts in Xi’an, China: a prospective study. BMJ Open. 2019;9(5):e023897. doi:10.1136/bmjopen-2018-023897.
  • Zhuang L, Xie X, Wang L, Weng X, Xiu Y, Liu D, Zhong L. Assessment of high-risk human papillomavirus infection characteristics in cervical squamous cell carcinoma and adenocarcinoma in china. Risk Manag Healthc Policy. 2022;15:2043–55. doi:10.2147/RMHP.S384342.
  • Gong Y, Wang Y, Zhou Q, Qu W, Chen F, Wang Y, Mo J, Zhang H, Lin L, Bi T, et al. The possible impact of novel mutations in human papillomavirus 52 on the infection characteristics. Microb Genomics. 2023;9(4). doi:10.1099/mgen.0.000962.
  • Wang X, Han S, Li X, Wang X, Wang S, Ma L. Prevalence and distribution of human papillomavirus (HPV) in Luoyang city of Henan province during 2015-2021 and the genetic variability of HPV16 and 52. Virol J. 2022;19(1):37. doi:10.1186/s12985-022-01759-5.
  • Song Z, Cui Y, Li Q, Deng J, Ding X, He J, Liu Y, Ju Z, Fang L. The genetic variability, phylogeny and functional significance of E6, E7 and LCR in human papillomavirus type 52 isolates in Sichuan, China. Virol J. 2021;18(1):94. doi:10.1186/s12985-021-01565-5.
  • Wang QY, Zhao XQ, Guo YC, Zhang L, Li XX, Wang Y. Relationship between E6 and E7 gene polymorphisms of human papillomavirus type 52 and cervical intraepithelial neoplasia. J Qingdao Univ. 2022;58:667–71.
  • Yang Z, He ZH, Zhang Y, Di XH, Zheng DF, Xu HH. Genetic variability in the E6 and E7 oncogenes of HPV52 and its prevalence in the Taizhou area, China. Virol J. 2022;19(1):194. doi:10.1186/s12985-022-01929-5.
  • Li Y, Zhou L, Liao Q, Liu H. Study of human papillomavirus type 52 genetic mutations and subtype classification collected in Beijing. Chin J Exp Clin Virol. 2016;30:558–61.
  • Zhao J, Zhan Q, Guo J, Liu M, Ruan Y, Zhu T, Han L, Li F. Phylogeny and polymorphism in the E6 and E7 of human papillomavirus: alpha-9 (HPV16, 31, 33, 52, 58), alpha-5 (HPV51), alpha-6 (HPV53, 66), alpha-7 (HPV18, 39, 59, 68) and alpha-10 (HPV6, 44) in women from Shanghai. Infect Agent Cancer. 2019;14(1):38. doi:10.1186/s13027-019-0250-9.
  • Chen Z, Jing Y, Wen Q, Ding X, Zhang S, Wang T, Zhang Y, Zhang J. L1 and L2 gene polymorphisms in HPV-58 and HPV-33: implications for vaccine design and diagnosis. Virol J. 2016;13(1):167. doi:10.1186/s12985-016-0629-9.
  • Wang Y, Han S, Wang X, Song S, Wang X. Characteristics of human papillomavirus infection among females and the genetic variations of HPV18 and HPV58 in Henan province, China. Sci Rep. 2023;13(1):2252. doi:10.1038/s41598-022-24641-4.
  • Chen Z, Jing Y, Wen Q, Ding X, Wang T, Mu X, Chenzhang Y, Cao M. E6 and E7 Gene Polymorphisms in Human Papillomavirus Types-58 and 33 Identified in Southwest China. PLOS ONE. 2017;12(1):e0171140. doi:10.1371/journal.pone.0171140.
  • Yang Z, Zhang C, Luo P, Ye M, Gong Q, Mei B. Genetic variability of E6 and E7 genes of human papillomavirus type 58 in jingzhou, Hubei Province of central China. Virol J. 2022;19(1):71. doi:10.1186/s12985-022-01801-6.
  • Yu JH, Shi WW, Zhou MY, Liu JM, Han QY, Xu HH. Genetic variability and oncogenic risk association of human papillomavirus type 58 E6 and E7 genes in Taizhou area, China. Gene. 2019;686:171–6. doi:10.1016/j.gene.2018.11.066.
  • Zhang S, Xu G, Ni H, Li S, Lv D. Distribution and variant spectrum of HPV58 infection in women with cervical infection in Ningbo. Zhonghua Yu Fang Yi Xue Za Zhi. 2017;18:91–6.
  • Liu Y, Pan Y, Gao W, Ke Y, Lu Z. Whole-genome analysis of human papillomavirus types 16, 18, and 58 isolated from cervical precancer and cancer samples in Chinese Women. Sci Rep. 2017;7(1):263. doi:10.1038/s41598-017-00364-9.
  • Jin R, Qian H, Zhang Y, Yuan D, Bao J, Zhou H, Chen M, Huang J, Yu H. The prevalence and genotype distribution of human papillomaviruses among women in Taizhou, China. Medicine (Baltimore). 2019;98(39):e17293. doi:10.1097/MD.0000000000017293.
  • Zhao S, Zhao X, Hu S, Lu J, Duan X, Zhang X, Chen F, Zhao F. Distribution of high-risk human papillomavirus genotype prevalence and attribution to cervical precancerous lesions in rural North China. Chin J C ancer R es. 2019;31(4):663–72. doi:10.21147/j.issn.1000-9604.2019.04.10.
  • Ni G, Huang K, Luan Y, Cao Z, Chen S, Ma B, Yuan J, Wu X, Chen G, Wang T, et al. Human papillomavirus infection among head and neck squamous cell carcinomas in southern China. PLOS ONE. 2019;14(9):e0221045. doi:10.1371/journal.pone.0221045.
  • Boon SS, Xia C, Lim JY, Chen Z, Law PTY, Yeung ACM, Thomas M, Banks L, Chan PKS. Human Papillomavirus 58 E7 T20I/G63S Variant Isolated from an East Asian Population Possesses High Oncogenicity. J Virol. 2020;94(8). doi:10.1128/JVI.00090-20.
  • Guan P, Howell-Jones R, Li N, Bruni L, de Sanjosé S, Franceschi S, Clifford GM. Human papillomavirus types in 115,789 HPV-positive women: a meta-analysis from cervical infection to cancer. Int J Cancer. 2012;131(10):2349–59. doi:10.1002/ijc.27485.
  • Orumaa M, Leinonen MK, Campbell S, Møller B, Myklebust T, Nygård M. Recent increase in incidence of cervical precancerous lesions in Norway: Nationwide study from 1992 to 2016. Int J Cancer. 2019;145(10):2629–38. doi:10.1002/ijc.32195.
  • McCredie MR, Sharples KJ, Paul C, Baranyai J, Medley G, Jones RW, Medley G, Jones RW, Skegg DC. Natural history of cervical neoplasia and risk of invasive cancer in women with cervical intraepithelial neoplasia 3: a retrospective cohort study. Lancet Oncol. 2008;9(5):425–34. doi:10.1016/S1470-2045(08)70103-7.
  • Kind AB, Pavelyev A, Kothari S, El Mouaddin N, Schmidt A, Morais E, Guggisberg P, Lienert F. Assessing the epidemiological impact on cervical cancer of switching from 4-valent to 9-valent HPV vaccine within a gender-neutral vaccination programme in Switzerland. BMC Public Health. 2020;20(1):671. doi:10.1186/s12889-020-08840-0.
  • Mix JM, Saraiya M, Senkomago V, Unger ER. High-Grade Vulvar, Vaginal, and anal precancers among U.S. Adolescents and young adults after human papillomavirus vaccine introduction. Am J Prev Med. 2022;62(1):95–9. doi:10.1016/j.amepre.2021.06.026.
  • Khawar L, McManus H, Vickers T, Chow EPF, Fairley CK, Donovan B, Machalek DA, Regan DG, Grulich AE, Guy RJ, et al. Genital warts trends in Australian and overseas-born people in Australia: A cross-sectional trend analysis to measure progress towards control and elimination. Lancet Reg Health West Pac. 2021;16:100251. doi:10.1016/j.lanwpc.2021.100251.
  • Diana G, Corica C. Human Papilloma virus vaccine and prevention of head and neck cancer, what is the current evidence? Oral Oncol. 2021;115:105168. doi:10.1016/j.oraloncology.2020.105168.
  • Zhao XL, Hu SY, Hu JW, Wang HH, Wen TM, Feng YS, Qiao Y-L, Zhao F-H, Zhang Y. Tackling barriers to scale up human papillomavirus vaccination in China: progress and the way forward. Infect Dis Poverty. 2023;12(1):86. doi:10.1186/s40249-023-01136-6.
  • Xie P, Zhao J, Li X, Zou X, Liu G, Han X. Preference for human papillomavirus vaccine type and vaccination strategy among parents of school-age girls in Guangdong province, China. Prev Med Rep. 2023;36:102463. doi:10.1016/j.pmedr.2023.102463.
  • Barnabas RV, Brown ER, Onono MA, Bukusi EA, Njoroge B, Winer RL, Galloway DA, Pinder LF, Donnell D, Wakhungu IN, et al. Durability of single-dose HPV vaccination in young Kenyan women: randomized controlled trial 3-year results. Nat Med. 2023;29(12):3224–32. doi:10.1038/s41591-023-02658-0.
  • Chan PK, Luk AC, Park JS, Smith-McCune KK, Palefsky JM, Konno R, Giovannelli L, Coutlée F, Hibbitts S, Chu T-Y, et al. Identification of human papillomavirus type 58 lineages and the distribution worldwide. J Infect Dis. 2011;203(11):1565–73. doi:10.1093/infdis/jir157.
  • Tenjimbayashi Y, Onuki M, Hirose Y, Mori S, Ishii Y, Takeuchi T, Tasaka N, Satoh T, Morisada T, Iwata T, et al. Whole-genome analysis of human papillomavirus genotypes 52 and 58 isolated from Japanese women with cervical intraepithelial neoplasia and invasive cervical cancer. Infect Agent Cancer. 2017;12(1):44. doi:10.1186/s13027-017-0155-4.
  • Choi YJ, Ki EY, Zhang C, Ho WC, Lee SJ, Jeong MJ, Chan PK, Park JS. Analysis of Sequence Variation and Risk Association of Human Papillomavirus 52 Variants Circulating in Korea. PloS One. 2016;11(12):e0168178. doi:10.1371/journal.pone.0168178.
  • Chang YJ, Chen HC, Lee BH, You SL, Lin CY, Pan MH, Chou Y-C, Hsieh C-Y, Chen YMA, Cheng Y-J, CBCSP-HPV Study Group. Unique variants of human papillomavirus genotypes 52 and 58 and risk of cervical neoplasia. Int J Cancer. 2011;129(4):965–73. doi:10.1002/ijc.25724.
  • Chan PKS, Luk ACS, Park J-S, Smith-McCune KK, Palefsky JM, Konno R, Giovannelli L, Coutlée F, Hibbitts S, Chu T-Y, et al. Identification of human papillomavirus type 58 lineages and the distribution worldwide. J Infect Dis. 2011;203(11):1565–73. doi:10.1093/infdis/jir157.
  • Pal A, Kundu R. Human papillomavirus E6 and E7: The cervical cancer hallmarks and targets for therapy. Front Microbiol. 2019;10:3116. doi:10.3389/fmicb.2019.03116.
  • Ding T, Wang X, Ye F, Cheng X, Ma D, Lu W, Xie X. Distribution of human papillomavirus 58 and 52 E6/E7 variants in cervical neoplasia in Chinese women. Gynecol Oncol. 2010;119(3):436–43. doi:10.1016/j.ygyno.2010.08.032.
  • Chan PKS, Lam CW, Cheung TH, Li WW, Lo KW, Chan MY, Cheung JL, Cheng AF. Association of human papillomavirus type 58 variant with the risk of cervical cancer. J Natl Cancer Inst. 2002;94(16):1249–53. doi:10.1093/jnci/94.16.1249.
  • Gillison ML, Koch WM, Capone RB, Spafford M, Westra WH, Wu L, Zahurak ML , Daniel RW, Viglione M, Symer DE, Shah KV et al. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst. 2000;92(9):709–20. doi:10.1093/jnci/92.9.709.
  • de Sanjosé S, Serrano B, Tous S, Alejo M, Lloveras B, Quirós B, Clavero O, Vidal A, Ferrándiz-Pulido C, Pavón MA, et al. Burden of Human Papillomavirus (HPV)-Related Cancers Attributable to HPVs 6/11/16/18/31/33/45/52 and 58. JNCI Cancer Spectr. 2018;2(4):ky045. doi:10.1093/jncics/pky045.
  • Yhim HY, Lee NR, Song EK, Kwak JY, Lee ST, Kim JH, Kim J-S, Park HS, Chung I-J, Shim H-J, et al. The prognostic significance of tumor human papillomavirus status for patients with anal squamous cell carcinoma treated with combined chemoradiotherapy. Int J Cancer. 2011;129(7):1752–60. doi:10.1002/ijc.25825.
  • Wei W, Shi Q, Guo F, Zhang BY, Chen C, Zhang NS, Dong XP. The distribution of human papillomavirus in tissues from patients with head and neck squamous cell carcinoma. Oncol Rep. 2012;28(5):1750–6. doi:10.3892/or.2012.1990.
  • Xu Y, Liu S, Yi H, Wang J, Luo Y, Yin S. Low prevalence of human papillomavirus in head and neck squamous cell carcinoma in Chinese patients. J Med Virol. 2015;87(2):281–6. doi:10.1002/jmv.24052.
  • Huang H, Zhang B, Chen W, Zhou SM, Zhang YX, Gao L, Xu ZG, Qiao YL, Tang PZ. Human papillomavirus infection and prognostic predictors in patients with oropharyngeal squamous cell carcinoma. Asian Pac J Cancer Prev. 2012;13(3):891–6. doi:10.7314/APJCP.2012.13.3.891.
  • Huang SF, Li HF, Liao CT, Wang HM, Chen IH, Chang JT, Chen Y-J, Cheng A-J. Association of HPV infections with second primary tumors in early-staged oral cavity cancer. Oral Dis. 2012;18(8):809–15. doi:10.1111/j.1601-0825.2012.01950.x.
  • Zainura A, Yalkun Y, Wu M. The different experession of human papilloma viral types 6 and 11 in Uyghur and Chinese juvenile recurrent respiratory papillomatosis in a large pediatric population in Xinjiang. J clin Otolaryngol, Head, and Neck Surg. 2013;27:1205–7.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.