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Research Article

Consultations for HIV post-exposure prophylaxis before and after health insurance coverage of pre-exposure prophylaxis to a university-based emergency department in Germany

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Article: 2207977 | Received 01 Nov 2022, Accepted 24 Apr 2023, Published online: 07 May 2023

References

  • An der Heiden MM, Kollan C, Schmidt D, Gunsenheimer-Bartmeyer B, Bremer V. Schätzung der Zahl der HIV-Neuinfektionen und der Gesamtzahl von Menschen mit HIV in Deutschland, Stand Ende 2020. Epid Bull. 2021;47:3–17.
  • WHO expands recommendation on oral pre-exposure prophylaxis of HIV infection (PrEP) (2015).
  • European Medicines Agency. First medicine for HIV pre-exposure prophylaxis recommended for approval in the EU. https://www.ema.europa.eu/en/news/first-medicine-hiv-pre-exposure-prophylaxis-recommended-approval-eu. Accessed 05/06, 2022.
  • Anlage 33 zum Bundesmantelvertrag-Ärzte (BMV-Ä) – Vereinbarung über die HIV-Präexpositionsprophylaxe zur Prävention einer HIV-Infektion gemäߧ 20j SGB V (24.7.2019).
  • Positively Aware – The HIV treatment journal. Truvada. https://www.positivelyaware.com/drug-guides/truvada. Accessed 05/06, 2022.
  • Spinner CD, Hanhoff N, Krznaric I, et al. 2016 PREP attitudes in Germany: high awareness and acceptance in MSM at risk of HIV. Infection. 2018;46(3):405–408.
  • Mysior P, Tenberken E, Stecher M, et al. Rapid uptake of pre-exposure prophylaxis after significant price reduction in Germany highlights importance of pre-exposure prophylaxis accessibility. AIDS Res Hum Retroviruses. 2020;36(9):721–733.
  • Koppe U, Marcus U, Albrecht S, et al. Factors associated with the informal use of HIV pre-exposure prophylaxis in Germany: a cross-sectional study. J Int AIDS Soc. 2019;22(10):e25395.
  • Bundesanzeiger. Gesetz für schnellere Termine und bessere Versorgung (Terminservice- und Versorgungsgesetz–TSVG). http://www.bgbl.de/xaver/bgbl/start.xav?startbk=Bundesanzeiger_BGBl&jumpTo=bgbl119s0646.pdf. Accessed 08/05, 2022.
  • Marcus U, Schmidt D, Schink SB, Koppe U. Analysis of HIV pre-exposure prophylaxis (PrEP) needs and PrEP use in Germany among men who have sex with men. J Public Health (Berl). 2022;1–17.
  • DAIG. Deutsch-Österreichische Leitlinie zur medikamentösen Postexpositionsprophylaxe (PEP) nach HIV-Exposition (Version 2022). https://www.awmf.org/uploads/tx_szleitlinien/055-004l_S2k_Medikamentoese-Postexpositionsprophylaxe-PEP-nach-HIV-Exposition_2022-04.pdf. Accessed 05/06, 2022;
  • Scholten M, Suarez I, Platten M, et al. To prescribe, or not to prescribe: decision making in HIV-1 post-exposure prophylaxis. HIV Med. 2018;19(9):645–653.
  • Malinverni S, Libois A, Gennotte AF, La Morté C, Mols P. Prescription of non-occupational post-exposure HIV prophylaxis by emergency physicians: an analysis on accuracy of prescription and compliance. PLoS One. 2016;11(4):e0153021.
  • Marzel A, Heinrich H, Schilliger L, et al. Prescription of postexposure prophylaxis for HIV-1 in the emergency room: correct transmission risk assessment remains challenging. J Acquir Immune Defic Syndr. 2017;74(4):359–366.
  • Leal L, Torres B, León A, et al. Predictive factors for HIV seroconversion among individuals attending a specialized center after an HIV risk exposure: a case-control study. AIDS Res Hum Retroviruses. 2016;32(10–11):1016–1021.
  • Jain S, Oldenburg CE, Mimiaga MJ, Mayer KH. Subsequent HIV infection among men who have sex with men who used non-occupational post-exposure prophylaxis at a Boston community health center: 1997–2013. AIDS Patient Care STDS. 2015;29(1):20–25.
  • Shull JA, Attys JM, Amutah-Onukagha NN, Hill MJ. Utilizing emergency departments for pre-exposure prophylaxis (PrEP). J Am Coll Emerg Physicians Open. 2020;1(6):1427–1435.
  • Stanley K, Lora M, Merjavy S, et al. HIV prevention and treatment: the evolving role of the emergency department. Ann Emerg Med. 2017;70(4):562–572. e3.
  • Zhao Z, Jones J, Sanders R, et al. Emergency Department (ED)-Based HIV Pre-Exposure Prophylaxis (PrEP) Referral Program–Using EDs as a Portal for PrEP Services. BMJ Publishing Group, Sexually Transmitted Infections; 2019;95:A213.
  • Ridgway JP, Almirol EA, Bender A, et al. Which patients in the emergency department should receive preexposure prophylaxis? Implementation of a predictive analytics approach. AIDS Patient Care STDS. 2018;32(5):202–207.
  • Haukoos JS, White DAE, Rowan SE, et al. Development of a 2-step algorithm to identify emergency department patients for HIV pre-exposure prophylaxis. Am J Emerg Med. 2022;51:6–12.
  • O'Donnell S, Bhate TD, Grafstein E, Lau W, Stenstrom R, Scheuermeyer FX. Missed opportunities for HIV prophylaxis among emergency department patients with occupational and nonoccupational body fluid exposures. Ann Emerg Med. 2016;68(3):315–323.e1.
  • O'Connell KA, Kisteneff AV, Gill SS, et al. HIV post-exposure prophylaxis in the emergency department: an updated assessment and opportunities for HIV prevention identified. Am J Emerg Med. 2021;46:323–328.
  • Biggs K, O'Sullivan M, Palmer C, et al. Post-exposure prophylaxis in the era of pre-exposure prophylaxis: a study of post-exposure prophylaxis use in South-East Queensland since the Pharmaceutical Benefits Scheme listing of pre-exposure prophylaxis. Int J STD AIDS. 2020;31(5):426–431.
  • Woodward SC, Baynes AM, Tyson HA, Dunlop WA, Martin SJ. Is non-occupational HIV post exposure prophylaxis (nPEP) still used? An exploration of nPEP use since widespread availability of HIV PrEP. Int J STD AIDS. 2022;33(10):914–919.
  • Gillespie L, Lowrie M, Metcalfe R. Has the introduction of HIV pre-exposure prophylaxis had an impact on HIV post-exposure prophylaxis for sexual exposure prescriptions in men who have sex with men in the UK’s largest health board? Sex Transm Infect. 2018;94(6):462–462.
  • Casalino E, Bouzid D, Antoniol S, et al. Characteristics of human immunodeficiency virus exposure and predictors of time until access to postexposure prophylaxis: a prospective observational study. Emergencias. 2021;33(1):35–41.
  • van Dijk M, de Wit JBF, Guadamuz TE, Martinez JE, Jonas KJ. Slow uptake of PrEP: behavioral predictors and the influence of price on PrEP uptake among MSM with a high interest in PrEP. AIDS Behav. 2021;25(8):2382–2390.
  • Uhrmacher M, Skaletz-Rorowski A, Nambiar S, et al. HIV pre-exposure prophylaxis during the SARS-CoV-2 pandemic: results from a prospective observational study in Germany. Front Public Health. 2022;10:930208.
  • Jongen VW, Zimmermann HM, Boyd A, et al. Transient changes in preexposure prophylaxis use and daily sexual behavior after the implementation of COVID-19 restrictions among men who have sex with men. J Acquir Immune Defic Syndr. 2021;87(5):1111–1118.
  • Thewes LC. Einsatz der HIV-Postexpositionsprophylaxe im klinischen Alltag am Beispiel der Bonner HIV-Ambulanz. Rheinische Friedrich-Wilhelms-Universität Bonn; 2021. https://hdl.handle.net/20.500.11811/8895. Acccessed 04/29/2023.
  • Oz N, Alon D, Stein GY, Turner D. Adherence and characteristics of HIV post-exposure prophylaxis for a population in Tel Aviv of men who have sex with men. Isr Med Assoc J. 2017;19(4):257–261.
  • Schlabe S, Boesecke C, Schwarze-Zander C, et al. Poster: HIV post-exposure prophylaxis (PEP)—the perspective of the A&E department at a tertiary referral centre with a specialized HIV centre. Paper presented at: Deutsch-Österreichischer AIDS-Kongress, 2021.