Polyvinylpyrrolidone–sodium hyaluronate gel (Gelclair^®): a bioadherent oral gel for the treatment of oral mucositis and other painful oral lesions

Bibliography

• American Cancer Society: ACS News Center. Mouth sores painful for patients: new scoring system to aid in treating mouth scores. Available at: http://www.cancer.org/docroot/NSW_1x_Mouth_Sores_painful_for_Patients.asp [assessed July 9 2008]
   Google Scholar
• Trotti A, Bellm LA, Epstein JB, et al. Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systemic literature review Radiother Oncol 2003;66:253-62
   PubMed Web of Science ®Google Scholar
• Sonis S. Oral mucositis in cancer therapy. J Support Oncol 2004;6(Suppl 3):3-8
   Google Scholar
• Stiff PJ. Continuing progress for a continuing need. Support Care Oncol 2007;(Suppl 2)
   Google Scholar
• Rose-Ed AM, Bellm LA, Epstein JB, et al. Complications of radiation therapy for head and neck cancers. The patient's perspective. Cancer Nurs 2002;25:468-9
   Google Scholar
• Speilberger R, Stiff P, Bensinger W, et al. Palifermin for oral mucositis after intensive therapy for hematologic cancers N Eng J M 2004;51:2590-8
   Google Scholar
• Keefe DM, Schubert MM, Elting LS, et al. Association of Supportive Care in Cancer and the International Society for Oral Oncology Cancer 2007;109(5)820-3
   Google Scholar
• Mahood DF, Dosoe AM, Loprinzi CL, et al. Inhibition of fluorouracil-induced stomatitis by oral cryotherapy. J Clin Oncol 1991;93:449-90
   Google Scholar
• McCarthy GM, Awde JD, Ghandi H, et al. Risk factors assoiciated with mucositis in cancer patients receiving 5-fluorouracil. Oral Oncol 1998;34(6):484-90
   PubMed Web of Science ®Google Scholar
• Lilleby K, Garcia P, Gooley T, et al. A prospective randomized study of cryotherapy during administration of high dose melphalan to decrease the severity and duration of oral mucositis in patient with multiple myeloma undergoing peripheral blood stem cell transplantation. Bone Marrow Trans 2006;37:1031-5
   PubMed Web of Science ®Google Scholar
• Gelclair® [package insert] (2006). EKR Therapeutics, Inc, Cedar Knolls, New Jersey
   Google Scholar
• Zaleski KJ, Dolodka T, Cawes-Bentley C, et al. Hyaluronic acid binding peptides prevent experimental staphylococcal wound infection 2006; Antimicrob Agents Chemother Am Soc Microbio 2006;3856-60
   Google Scholar
• Hita-Iglesias P. Torre-Lagares, Gutiérrez-Pérez. Evaluation of the clinical behaviour of a polyvinylpyrrolidone and sodium hyalonurate gel (Gelclair®) in patients subjected to surgical treatment with CO2 laser. Int J Oral Maxillofac Surg 2006;35:514-7
   PubMed Web of Science ®Google Scholar
• Lee, JS, Young-Sunm C, Lee JW, et al. Preparation of wound dressing using hydrogel polyurethane foam. Trends Biomater Artif Orig 2001;15:4-6
   Google Scholar
• National Cancer Institute (2007). Pilot study of polyvinylpyrrolidone-sodium hyaluronate gel in reducing the pain of oral mucositis in pediatric patients with cancer. Available from: www.cancer.gov/PDQ^® [Last accessed July 6 2008] clinical trials
   Google Scholar
• Bensinger W, Schubert M, Ang K, et al. (2008). NCCN Task Force: prevention and management of mucositis J Nat Compr Cancer Netw 2008;6(suppl)51-21
   Google Scholar
• Inoue H, Shibata S, Koshihar Y. Modulation by glycyrrhetinic acid derivatives of TPA-induced mouse ear odeman. Brit J Pharm 1989:204-10
   PubMedGoogle Scholar
• Digenis GA, Wells DA, Ansell JM, et al. Disposition of [14C]povidone after oral administration to the rat. Food Chem Toxic 1987;25:241-3
   PubMed Web of Science ®Google Scholar
• Bastow ER, Byers S, Golub SB, et al. Hyaluronan synthesis and degradation in cartilage and bone. Cell Mol Life Sci 2008;65:395-413
   PubMed Web of Science ®Google Scholar
• De Cordi M, D'andrea P, Giorgiutti E. Gelclair, potentially an efficacious treatment for chemotherapy-induced mucositis. Italian Tumour League III Congress for Professional Oncology Nurses; 10-12 October 2001 Conegliano
   Google Scholar
• Innocenti M, Moscatellig G, Lopez S, et al. Efficacy of Gelcair® in reducing pain in palliative care patients with oral lesions: preliminary findings from an open pilot study. J Pain Symptom Manag 2002;24:456-45
   PubMed Web of Science ®Google Scholar
• Barber C, Powell R, Ellis A, et al. Comparing pain control and ability to eat and drink with standard therapy vs Gelclair; a preliminary, double centre, randomized controlled on patients with radiotherapy-induced oral mucositis Support Care Cancer 2007;15:427-40
   PubMed Web of Science ®Google Scholar
• Flook C, Calman F, Mant M, et al. Gelclair vs benzydamine in a randomized controlled study in patients with oral mucositis due to radical radiotherapy. Support Car Cancer 2005;13:401-83
   Google Scholar
• Epstein JB, Silverman S Jr, Paggiarino DA, et al. Benzydamine HCl for prophylaxis of radiation-induced oral mucositis: results from a multicenter, randomized, double-blind, placebo-controlled clinical trial. Cancer 2001;92:875
   PubMed Web of Science ®Google Scholar
• Cawley MM, Benson L. Current trends in managing oral mucositis. Clin J Oncol Nurs 2005;9(5):584-92
   PubMedGoogle Scholar