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Clinical Epidemiology Volume 15, 2023 - Issue
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COMMENTARY

Use of the CPRD Aurum Database: Insights Gained from New Data Quality Assessments

Susan Jick1 Epidemiology, Boston Collaborative Drug Surveillance Program, Lexington, MA, USA;2 Epidemiology, Boston University School of Public Health, Boston, MA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2215-1067View further author information
ORCID Icon,
Catherine Vasilakis-Scaramozza1 Epidemiology, Boston Collaborative Drug Surveillance Program, Lexington, MA, USAORCID Iconhttps://orcid.org/0000-0002-8721-4604View further author information
ORCID Icon,
Rebecca Persson1 Epidemiology, Boston Collaborative Drug Surveillance Program, Lexington, MA, USAORCID Iconhttps://orcid.org/0000-0003-2979-3238View further author information
ORCID Icon,
David Neasham3 Center for Observational Research, Amgen Ltd, Uxbridge, UKView further author information
,
George Kafatos3 Center for Observational Research, Amgen Ltd, Uxbridge, UKORCID Iconhttps://orcid.org/0000-0001-7871-9216View further author information
ORCID Icon &
Katrina Wilcox Hagberg1 Epidemiology, Boston Collaborative Drug Surveillance Program, Lexington, MA, USAORCID Iconhttps://orcid.org/0000-0002-2407-2995View further author information
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Pages 1219-1222 | Received 10 Aug 2023, Accepted 29 Nov 2023, Published online: 26 Feb 2024

References

  • Hagberg KW, Vasilakis-Scaramozza C, Persson R, Kafatos G, Neasham D, Jick S. Presence of Breast Cancer Information Recorded in United Kingdom Primary Care Databases: Comparison of CPRD Aurum and CPRD GOLD (Companion Paper 1). Clin Epidemiol. 2023;15:1183–1192. doi:10.2147/CLEP.S434795
  • Vasilakis-Scaramozza C, Hagberg KW, Persson R, et al. Comparison of Rheumatoid Arthritis Information Recorded in UK CPRD Aurum and CPRD GOLD Databases (Companion Paper 3). Clin Epidemiol. 2023;15:1207–1218. doi:10.2147/CLEP.S434831.
  • Hagberg KW, Vasilakis-Scaramozza C, Persson R, Neasham D, Kafatos G, Jick S. Correctness and Completeness of Breast Cancer Diagnoses Recorded in UK CPRD Aurum and CPRD GOLD Databases: Comparison to Hospital Episode Statistics and Cancer Registry (Companion Paper 2). Clin Epidemiol. 2023;15:1193–1206. doi:10.2147/CLEP.S434829
  • Jick S, Hagberg KW, Persson R, et al. Quality and completeness of diagnoses recorded in the new CPRD Aurum Database: evaluation of pulmonary embolism. Pharmacoepidemiol Drug Saf. 2020;29(9):1134–1140. doi:10.1002/pds.4996
  • Persson R, Sponholtz T, Vasilakis-Scaramozza C, et al. Quality and completeness of myocardial infarction recording in Clinical Practice Research Datalink Aurum. Clin Epidemiol. 2021;13:745–75. doi:10.2147/CLEP.S319245.
  • Hagberg KW, Vasilakis-Scaramozza C, Persson R, et al. Quality and completeness of malignant cancer recording in United Kingdom Clinical Practice Research Datalink Aurum compared to Hospital Episode Statistics. Annals of Cancer Epi. 2022;6:6. doi:10.21037/ace-22-4
  • Persson R, Vasilakis-Scaramozza C, Hagberg KW, et al. CPRD Aurum database: assessment of data quality and completeness of three important comorbidities. Pharmacoepidemiol Drug Saf. 2020;29:1456–1464. doi:10.1002/pds.5135
  • Vasilakis-Scaramozza C, Hagberg KW, Persson R, et al. Quality of rheumatoid arthritis recording in United Kingdom Clinical Practice Research Datalink Aurum. Pharmacoepidemiol Drug Saf. 2023;32:73–77. doi:10.1002/pds.5551
  • Persson R, Hagberg KW, Vasilakis-Scaramozza C, et al. Presence of codes for indication for use in Clinical Practice Research Datalink Aurum: an assessment of benign prostatic hyperplasia treatments. Clin Epi. 2022;Volume 14:641–652. doi:10.2147/CLEP.S360843
  • Gulliford MC, Sun X, Anjuman T, Yelland E, Murray-Thomas T. Comparison of antibiotic prescribing records in two UK primary care electronic health record systems: cohort study using CPRD GOLD and CPRD Aurum databases. BMJ Open. 2020;10:e038767.
  • Wolf A, Dedman D, Campbell J, et al. Data resource profile: Clinical Practice Research Datalink (CPRD) Aurum. Int J Epi. 2019;1740. doi:10.1093/ije/dyz034
  • Medicines & Healthcare Products Regulatory Agency. Hospital Episode Statistics (HES) Outpatient Care and CPRD primary care data documentation. Available from: https://cprd.com/sites/default/files/2022-02/Documentation_HES_OP_set21.pdf. Accessed November 30, 2023.
  • Strongman H, Williams R, Bhaskaran K. What are the implications of using individual and combined sources of routinely collected data to identify and characterise incident site-specific cancers? A concordance and validation study using linked English electronic health records data. BMJ Open. 2020;10:e037719. doi:10.1136/bmjopen-2020-037719

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