GSTP1 rs4147581 C>G and NLRP3 rs3806265 T>C as Risk Factors for Chronic Obstructive Pulmonary Disease: A Case-Control Study

References

• Celli B, Fabbri L, Criner G, et al. Definition and nomenclature of chronic obstructive pulmonary disease: time for its revision. Am J Respir Crit Care Med. 2022;206(11):1317–1325. doi:10.1164/rccm.202204-0671PP
   PubMed Web of Science ®Google Scholar
• Soler N, Esperatti M, Ewig S, et al. Sputum purulence-guided antibiotic use in hospitalised patients with exacerbations of COPD. Europ resp J. 2012;40:1344–1353. doi:10.1183/09031936.00150211
   PubMed Web of Science ®Google Scholar
• Blakemore A, Dickens C, Chew-Graham CA, et al. Depression predicts emergency care use in people with chronic obstructive pulmonary disease: a large cohort study in primary care. Int J Chronic Obstr. 2019;14:1343–1353. doi:10.2147/COPD.S179109
   PubMed Web of Science ®Google Scholar
• Agustí A, Vogelmeier C, Faner R. COPD 2020: changes and challenges. Am J Physiol Lung Cell Mol Physiol. 2020;319:L879–L883. doi:10.1152/ajplung.00429.2020
   PubMed Web of Science ®Google Scholar
• Wang C, Xu J, Yang L, et al. Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study. Lancet. 2018;391:1706–1717. doi:10.1016/S0140-6736(18)30841-9
   PubMed Web of Science ®Google Scholar
• Zhou M, Wang H, Zhu J, et al. Cause-specific mortality for 240 causes in China during 1990–2013: a systematic subnational analysis for the Global Burden of Disease Study 2013. Lancet. 2016;387:251–272. doi:10.1016/S0140-6736(15)00551-6
   PubMed Web of Science ®Google Scholar
• Kessler R, Partridge MR, Miravitlles M, et al. Symptom variability in patients with severe COPD: a pan-European cross-sectional study. Europ resp J. 2011;37:264–272. doi:10.1183/09031936.00051110
   PubMed Web of Science ®Google Scholar
• Montes de Oca M, Perez-Padilla R, Tálamo C, et al. Acute bronchodilator responsiveness in subjects with and without airflow obstruction in five Latin American cities: the PLATINO study. Pulmon Pharmacol Ther. 2010;23:29–35. doi:10.1016/j.pupt.2009.09.005
   PubMed Web of Science ®Google Scholar
• Silverman EK. Genetics of COPD. Annu Rev Physiol. 2020;82:413–431. doi:10.1146/annurev-physiol-021317-121224
   PubMed Web of Science ®Google Scholar
• He Y, Jiang B, Li LS, et al. Secondhand smoke exposure predicted COPD and other tobacco-related mortality in a 17-year cohort study in China. Chest. 2012;142(4):909–918. doi:10.1378/chest.11-2884
   PubMed Web of Science ®Google Scholar
• Forey BA, Thornton AJ, Lee PN. Systematic review with meta-analysis of the epidemiological evidence relating smoking to COPD, chronic bronchitis and emphysema. BMC Pulm Med. 2011;11:36. doi:10.1186/1471-2466-11-36
   PubMed Web of Science ®Google Scholar
• Eisner MD, Balmes J, Katz PP, et al. Lifetime environmental tobacco smoke exposure and the risk of chronic obstructive pulmonary disease. Environ Health. 2005;4:7. doi:10.1186/1476-069X-4-7
   PubMedGoogle Scholar
• Wang B, Xiao D, Wang C. Smoking and chronic obstructive pulmonary disease in Chinese population: a meta-analysis. Clin Respir J. 2015;9:165–175. doi:10.1111/crj.12118
   PubMed Web of Science ®Google Scholar
• Lai HC, Lin TL, Chen TW, et al. Gut microbiota modulates COPD pathogenesis: role of anti-inflammatory Parabacteroides goldsteinii lipopolysaccharide. Gut. 2022;71:309–321. doi:10.1136/gutjnl-2020-322599
   PubMed Web of Science ®Google Scholar
• Confalonieri M, Braga L, Salton F, et al. Chronic obstructive pulmonary disease definition: is it time to incorporate the concept of failure of lung regeneration? Am J Respir Crit Care Med. 2023;207(3):366–367. doi:10.1164/rccm.202208-1508LE
   PubMed Web of Science ®Google Scholar
• Zhou H, Yang J, Li D, et al. Association of IREB2 and CHRNA3/5 polymorphisms with COPD and COPD-related phenotypes in a Chinese Han population. J Human Gene. 2012;57:738–746. doi:10.1038/jhg.2012.104
   PubMed Web of Science ®Google Scholar
• Yuan C, Chang D, Lu G, et al. Genetic polymorphism and chronic obstructive pulmonary disease. Int J Chronic Obstr. 2017;12:1385–1393. doi:10.2147/COPD.S134161
   PubMed Web of Science ®Google Scholar
• Stankovic M, Nikolic A, Nagorni-Obradovic L, et al. Gene-gene interactions between glutathione S-transferase M1 and matrix metalloproteinases 1, 9, and 12 in chronic obstructive pulmonary disease in serbians. COPD. 2017;14:581–589. doi:10.1080/15412555.2017.1369022
   PubMedGoogle Scholar
• Zuntar I, Petlevski R, Dodig S, et al. GSTP1, GSTM1 and GSTT1 genetic polymorphisms and total serum GST concentration in stable male COPD. Acta Pharm. 2014;64:117–129. doi:10.2478/acph-2014-0003
   PubMed Web of Science ®Google Scholar
• Zhong L, Zhang YP, Fu WP, et al. The relationship between GSTP1 I105V polymorphism and COPD: a reappraisal. Am J Respir Crit Care Med. 2010;181:763–765. doi:10.1164/ajrccm.181.7.763
   PubMed Web of Science ®Google Scholar
• Yan F, Chen C, Jing J, et al. Association between polymorphism of glutathione S-transferase P1 and chronic obstructive pulmonary disease: a meta-analysis. Respir Med. 2010;104:473–480. doi:10.1016/j.rmed.2010.01.009
   PubMed Web of Science ®Google Scholar
• Ishii T, Matsuse T, Teramoto S, et al. Glutathione S-transferase P1 (GSTP1) polymorphism in patients with chronic obstructive pulmonary disease. Thorax. 1999;54:693–696. doi:10.1136/thx.54.8.693
   PubMed Web of Science ®Google Scholar
• Yim JJ, Park GY, Lee CT, et al. Genetic susceptibility to chronic obstructive pulmonary disease in Koreans: combined analysis of polymorphic genotypes for microsomal epoxide hydrolase and glutathione S-transferase M1 and T1. Thorax. 2000;55:121–125. doi:10.1136/thorax.55.2.121
   PubMed Web of Science ®Google Scholar
• Yang L, Li X, Tong X, et al. Association between glutathione S-transferase P1 Ile (105) Val gene polymorphism and chronic obstructive pulmonary disease: a meta-analysis based on seventeen case-control studies. Meta Gene. 2015;6:59–64. doi:10.1016/j.mgene.2015.08.007
   PubMedGoogle Scholar
• Yang Q, Huang W, Yin D, et al. EPHX1 and GSTP1 polymorphisms are associated with COPD risk: a systematic review and meta-analysis. Front Genetics. 2023;14:1128985. doi:10.3389/fgene.2023.1128985
   PubMed Web of Science ®Google Scholar
• Du Y, Zhang H, Xu Y, et al. Association among genetic polymorphisms of GSTP1, HO-1, and SOD-3 and chronic obstructive pulmonary disease susceptibility. Int J Chronic Obstr. 2019;14:2081–2088. doi:10.2147/COPD.S213364
   PubMed Web of Science ®Google Scholar
• Mo R, Li J, Chen Y, et al. lncRNA GAS5 promotes pyroptosis in COPD by functioning as a ceRNA to regulate the miR-223-3p/NLRP3 axis. Molecul Med Rep. 2022;26:219. doi:10.3892/mmr.2022.12735
   PubMed Web of Science ®Google Scholar
• Faner R, Sobradillo P, Noguera A, et al. The inflammasome pathway in stable COPD and acute exacerbations. ERJ Open Res. 2016;2:2. doi:10.1183/23120541.00002-2016
   PubMedGoogle Scholar
• Eltom S, Stevenson CS, Rastrick J, et al. P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke. PLoS One. 2011;6:e24097. doi:10.1371/journal.pone.0024097
   PubMed Web of Science ®Google Scholar
• Mahalanobish S, Dutta S, Saha S, et al. Melatonin induced suppression of ER stress and mitochondrial dysfunction inhibited NLRP3 inflammasome activation in COPD mice. Food and Chemical Toxicology. 2020;144:111588.
   PubMed Web of Science ®Google Scholar
• Zhang MY, Jiang YX, Yang YC, et al. Cigarette smoke extract induces pyroptosis in human bronchial epithelial cells through the ROS/NLRP3/caspase-1 pathway. Life Sci. 2021;269:119090. doi:10.1016/j.lfs.2021.119090
   PubMed Web of Science ®Google Scholar
• Cheng L, Yin R, Yang S, et al. Rs4612666 Polymorphism of the NLRP3 gene is associated with the occurrence of large artery atherosclerotic ischemic strokes and microembolic signals. Biomed Res. Int. 2018;2018:6345805. doi:10.1155/2018/6345805
   PubMed Web of Science ®Google Scholar
• Zhou D, Wang X, Chen T, et al. The NLRP3 rs10754558 polymorphism is associated with the occurrence and prognosis of coronary artery disease in the Chinese han population. Biomed Res. Int. 2016;2016:3185397. doi:10.1155/2016/3185397
   PubMed Web of Science ®Google Scholar
• Sui J, Li H, Fang Y, et al. NLRP1 gene polymorphism influences gene transcription and is a risk factor for rheumatoid arthritis in han Chinese. Arthritis Rheum. 2012;64:647–654. doi:10.1002/art.33370
   PubMed Web of Science ®Google Scholar
• Von Herrmann KM, Salas LA, Martinez EM, et al. NLRP3 expression in mesencephalic neurons and characterization of a rare NLRP3 polymorphism associated with decreased risk of Parkinson’s disease. NPJ Parkinson’s Dis. 2018;4:24. doi:10.1038/s41531-018-0061-5
   PubMed Web of Science ®Google Scholar
• Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (2023 report). Avaliable from: https://goldcopd.org/2023-gold-report-2/. Accessed February 7, 2024.
   Google Scholar
• Gattás GJ, Kato M, Soares-Vieira JA, et al. Ethnicity and glutathione S-transferase (GSTM1/GSTT1) polymorphisms in a Brazilian population. Braz J Med Biol Res. 2004;37:451–458. doi:10.1590/s0100-879x2004000400002
   PubMed Web of Science ®Google Scholar
• Tomaki M, Sugiura H, Koarai A, et al. Decreased expression of antioxidant enzymes and increased expression of chemokines in COPD lung. Pulmon Pharmacol Ther. 2007;20:596–605. doi:10.1016/j.pupt.2006.06.006
   PubMed Web of Science ®Google Scholar
• Ishii T, Matsuse T, Igarashi H, et al. Tobacco smoke reduces viability in human lung fibroblasts: protective effect of glutathione S-transferase P1. Am J Physiol Lung Cell Mol Physiol. 2001;280:L1189–L1195. doi:10.1152/ajplung.2001.280.6.L1189
   PubMed Web of Science ®Google Scholar
• Guo P, Li R, Piao TH, et al. Pathological mechanism and targeted drugs of COPD. Int J Chronic Obstr. 2022;17:1565–1575. doi:10.2147/COPD.S366126
   PubMed Web of Science ®Google Scholar
• Chen X, Liu G, Yuan Y, et al. NEK7 interacts with NLRP3 to modulate the pyroptosis in inflammatory bowel disease via NF-κB signaling. Cell Death Dis. 2019;10:906. doi:10.1038/s41419-019-2157-1
   PubMed Web of Science ®Google Scholar
• Wang Z, Qu K, Niu W, et al. Glutathione S-transferase P1 gene rs4147581 polymorphism predicts overall survival of patients with hepatocellular carcinoma: evidence from an enlarged study. Tumour Biol. 2016;37:943–952. doi:10.1007/s13277-015-3871-7
   PubMedGoogle Scholar
• Phuthong S, Settheetham-Ishida W, Natphopsuk S, et al. Genetic Polymorphism of the Glutathione S-transferase Pi 1 (GSTP1) and susceptibility to cervical cancer in human papilloma virus infected Northeastern Thai Women. Asian Pac J Cancer Prev. 2018;19:381–385. doi:10.22034/APJCP.2018.19.2.381
   PubMedGoogle Scholar
• Mukhammadiyeva GF, Bakirov AB, Karimov DO, et al. Analysis of the GSTP1 rs1695 polymorphism association with the development of asthma and phenotypic manifestations. J Asthma. 2022;59:1065–1069. doi:10.1080/02770903.2021.1910295
   PubMed Web of Science ®Google Scholar
• Dasgupta RK, Adamson PJ, Davies FE, et al. Polymorphic variation in GSTP1 modulates outcome following therapy for multiple myeloma. Blood. 2003;102:2345–2350. doi:10.1182/blood-2003-02-0444
   PubMed Web of Science ®Google Scholar
• Zhong S, Huang M, Yang X, et al. Relationship of glutathione S-transferase genotypes with side-effects of pulsed cyclophosphamide therapy in patients with systemic lupus erythematosus. Br. J. Clin. Pharmacol. 2006;62:457–472. doi:10.1111/j.1365-2125.2006.02690.x
   PubMed Web of Science ®Google Scholar
• Imani D, Azimi A, Salehi Z, et al. Association of nod-like receptor protein-3 single nucleotide gene polymorphisms and expression with the susceptibility to relapsing-remitting multiple sclerosis. Int J Immunogene. 2018;45:329–336. doi:10.1111/iji.12401
   PubMed Web of Science ®Google Scholar
• Agah E, Nafissi S, Saleh F, et al. Investigating the possible association between NLRP3 gene polymorphisms and myasthenia gravis. Muscle and Nerve. 2021;63:730–736. doi:10.1002/mus.27193
   PubMed Web of Science ®Google Scholar
• Cheng L, Liang X, Qian L, et al. NLRP3 gene polymorphisms and expression in rheumatoid arthritis. Exp Ther Med. 2021;22:1110.
   PubMed Web of Science ®Google Scholar
• La Russa A, Lofaro D, Montesanto A, et al. Association between NLRP3 rs10754558 and CARD8 rs2043211 variants and susceptibility to chronic kidney disease. Int J Mol Sci. 2023;24:1110. doi:10.3892/etm.2021.10544
   PubMed Web of Science ®Google Scholar
• Dawood A, Shehata W. Evaluation of NLRP3 (rs10754558) and PTPN22 (1858C/T) (rs2476601) functional polymorphisms in psoriasis susceptibility in Egypt. Appl Clin Gene. 2021;14:331–339. doi:10.2147/TACG.S319065
   Web of Science ®Google Scholar
• Qu K, Liu SS, Wang ZX, et al. Polymorphisms of glutathione S-transferase genes and survival of resected hepatocellular carcinoma patients. World J Gastroenterol. 2015;21:4310–4322. doi:10.3748/wjg.v21.i14.4310
   PubMed Web of Science ®Google Scholar
• Kelley N, Jeltema D, Duan Y, et al. The NLRP3 inflammasome: an overview of mechanisms of activation and regulation. Int J Mol Sci. 2019;20:3328. doi:10.3390/ijms20133328
   PubMed Web of Science ®Google Scholar
• Yadav H, Pandit D, Singh S, et al. GST polymorphism as a predictive biomarker for modulating the susceptibility to chronic obstructive pulmonary disease: a North Indian study. Exp Physiol. 2023. doi:10.1113/EP091339
   PubMed Web of Science ®Google Scholar
• Li S, Lin L, Zhao J, et al. The Study of the Influence of IL5RA variants on chronic obstructive pulmonary disease. COPD. 2023;20(1):338–347. doi:10.1080/15412555.2023.2270729
   PubMedGoogle Scholar
• Castro MCS, Nani ASF, Salum KCR, et al. Genetic polymorphisms and their effects on the severity of silicosis in workers exposed to silica in Brazil. J Bras Pneumol. 2022;48(5):e20220167. doi:10.36416/1806-3756/e20220167
   PubMed Web of Science ®Google Scholar
• Cheng Z, Zhang Y, Zhao R, et al. A novel circRNA-SNP may increase susceptibility to silicosis. Ecotoxicol Environ Saf. 2022;242:113855. doi:10.1016/j.ecoenv.2022.113855
   PubMed Web of Science ®Google Scholar