Penehyclidine for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Gynecological Laparoscopic Surgery Under Combined Intravenous and Inhalation Anesthesia: A Randomized, Double-Blind, Placebo-Controlled Trial

References

• Apfel CC, Korttila K, Abdalla M, et al. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med. 2004;350(24):2441–2451. doi:10.1056/NEJMoa032196
   PubMed Web of Science ®Google Scholar
• Habib AS, Gan TJ. Evidence-based management of postoperative nausea and vomiting: a review. Can J Anaesth. 2004;51:326–341. doi:10.1007/BF03018236
   PubMed Web of Science ®Google Scholar
• Apfel CC, Läärä E, Koivuranta M, Greim CA, Roewer N. A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers. Anesthesiology. 1999;91(3):693–700. doi:10.1097/00000542-199909000-00022
   PubMed Web of Science ®Google Scholar
• Sinclair DR, Chung F, Mezei G. Can postoperative nausea and vomiting be predicted? Anesthesiology. 1999;91:109–118. doi:10.1097/00000542-199907000-00018
   PubMed Web of Science ®Google Scholar
• Gan TJ, Belani KG, Bergese S, et al. Fourth consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg. 2020;131:411–448. doi:10.1213/ANE.0000000000004833
   PubMed Web of Science ®Google Scholar
• Tao B, Liu K, Wang D, et al. Effect of intravenous oxycodone versus sufentanil on the incidence of postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery. J Clin Pharmacol. 2019;59:1144–1150. doi:10.1002/jcph.1408
   PubMed Web of Science ®Google Scholar
• Zheng XZ, Cheng B, Luo J, et al. The characteristics and risk factors of the postoperative nausea and vomiting in female patients undergoing laparoscopic sleeve gastrectomy and laparoscopic gynecological surgeries: a propensity score matching analysis. Eur Rev Med Pharmacol Sci. 2021;25:182–189. doi:10.26355/eurrev_202101_24383
   PubMed Web of Science ®Google Scholar
• Horn CC, Wallisch WJ, Homanics GE, et al. Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting. Eur J Pharmacol. 2014;722:55–66. doi:10.1016/j.ejphar.2013.10.037
   PubMed Web of Science ®Google Scholar
• Ames WA, Machovec K. An update on the management of PONV in a pediatric patient. Best Pract Res Clin Anaesthesiol. 2020;34:749–758. doi:10.1016/j.bpa.2020.05.007
   PubMed Web of Science ®Google Scholar
• Pergolizzi JV, Philip BK, Leslie JB, Taylor R, Raffa RB. Perspectives on transdermal scopolamine for the treatment of postoperative nausea and vomiting. J Clin Anesth. 2012;24(4):334–345. doi:10.1016/j.jclinane.2011.07.019
   PubMed Web of Science ®Google Scholar
• Zhong W, Shahbaz O, Teskey G, et al. Mechanisms of nausea and vomiting: current knowledge and recent advances in intracellular emetic signaling systems. Int J Mole Sci. 2021;22(11). doi:10.3390/ijms22115797
   Web of Science ®Google Scholar
• Antor MA, Uribe AA, Erminy-Falcon N, et al. The effect of transdermal scopolamine for the prevention of postoperative nausea and vomiting. Front Pharmacol. 2014;5:55. doi:10.3389/fphar.2014.00055
   PubMed Web of Science ®Google Scholar
• Wang Y, Gao Y, Ma J, et al. Pleiotropic effects and pharmacological properties of penehyclidine hydrochloride. Drug Design Dev. 2018;12:3289–3299. doi:10.2147/DDDT.S177435
   PubMed Web of Science ®Google Scholar
• Xiao H, Liao Z, Tong R, et al. Penehyclidine hydrochloride: a potential drug for treating COPD by attenuating toll-like receptors. Drug Design Dev. 2012;6:317–322. doi:10.2147/DDDT.S36555
   PubMed Web of Science ®Google Scholar
• Sun J, Cao X, Lu T, Li N, Min X, Ding Z. Penehyclidine mitigates postoperative nausea and vomiting and intraoperative oculocardiac reflex in patients undergoing strabismus surgery: a prospective, randomized, double-blind comparison. BMC Anesthesiol. 2021;21(1):49. doi:10.1186/s12871-021-01266-0
   PubMed Web of Science ®Google Scholar
• Ding X, Chen D, Che J, Xu S, Liang H, Gui B. Penehyclidine hydrochloride for treating postoperative nausea and vomiting after laparoscopic bariatric surgery: a double-blinded randomized controlled trial. BMC Anesthesiol. 2023;23(1):135. doi:10.1186/s12871-023-02078-0
   PubMed Web of Science ®Google Scholar
• Lu T, Li R, Sun J, Chen J. Evaluation of penehyclidine for prevention of postoperative nausea and vomiting in patients undergoing total thyroidectomy under total intravenous anaesthesia with propofol-remifentanil. BMC Anesthesiol. 2022;22(1):317. doi:10.1186/s12871-022-01857-5
   PubMed Web of Science ®Google Scholar
• Wang LK, Cheng T, Yang XD, Xiong GL, Li N, Wang DX. Penehyclidine for prevention of postoperative nausea and vomiting following bimaxillary orthognathic surgery: a randomized, double-blind, controlled trial. J Anesth. 2022;36(1):122–136. doi:10.1007/s00540-021-03017-4
   PubMed Web of Science ®Google Scholar
• Stark PA, Myles PS, Burke JA. Development and psychometric evaluation of a postoperative quality of recovery score: the QoR-15. Anesthesiology. 2013;118(6):1332–1340. doi:10.1097/ALN.0b013e318289b84b
   PubMed Web of Science ®Google Scholar
• Yang H, Gu X, Xu M, et al. Preventing nausea and vomiting after gynecological laparoscopic surgery by patient-controlled intravenous analgesia with a naloxone admixture: a randomized controlled trial. Medicine. 2022;101(29):e29584. doi:10.1097/MD.0000000000029584
   PubMed Web of Science ®Google Scholar
• Myles PS, Myles DB, Galagher W, Chew C, MacDonald N, Dennis A. Minimal clinically important difference for Three Quality of Recovery Scales. Anesthesiology. 2016;125(1):39–45. doi:10.1097/ALN.0000000000001158
   PubMed Web of Science ®Google Scholar
• Arslan M, Ciçek R, Kalender HÜ, Yilmaz H. Preventing postoperative nausea and vomiting after laparoscopic cholecystectomy: a prospective, randomized, double-blind study. Curr Ther Res Clin Exp. 2011;72(1):1–12. doi:10.1016/j.curtheres.2011.02.002
   PubMed Web of Science ®Google Scholar
• Klockgether-Radke A, Piorek V, Crozier T, Kettler D. Nausea and vomiting after laparoscopic surgery: a comparison of propofol and thiopentone/halothane anaesthesia. Eur J Anaesthesiol. 1996;13(1):3–9. doi:10.1097/00003643-199601000-00002
   PubMed Web of Science ®Google Scholar
• Guo W, Ding J, Jin X, Li G. Effect of cerebral oxygen saturation on postoperative nausea and vomiting in female laparoscopic surgery patients. Medicine. 2017;96(41):e8275. doi:10.1097/MD.0000000000008275
   PubMed Web of Science ®Google Scholar
• Besir A, Tugcugil E. Comparison of different end-tidal carbon dioxide levels in preventing postoperative nausea and vomiting in gynaecological patients undergoing laparoscopic surgery. J Obstet Gynaecol. 2021;41(5):755–762. doi:10.1080/01443615.2020.1789961
   PubMedGoogle Scholar
• Gin E, Lowen D, Tacey M, Hodgson R. Reduced laparoscopic intra-abdominal pressure during laparoscopic cholecystectomy and its effect on post-operative pain: a double-blinded randomised control trial. J Gastrointest Surg. 2021;25(11):2806–2813. doi:10.1007/s11605-021-04919-0
   PubMed Web of Science ®Google Scholar
• Zhang Z, Zhuang Y, Ouyang F, Zhang A, Zeng B, Gu M. Penehyclidine enhances the efficacy of tropisetron in prevention of PONV following gynecological laparoscopic surgery. J Anesth. 2012;26(6):864–869. doi:10.1007/s00540-012-1443-1
   PubMed Web of Science ®Google Scholar
• Rong X, Ding ZC, Yu HD, Yao SY, Zhou ZK. Risk factors of postoperative delirium in the knee and Hip replacement patients: a systematic review and meta-analysis. J Orthop Surg Res. 2021;16(1):76. doi:10.1186/s13018-020-02127-1
   PubMed Web of Science ®Google Scholar
• Uzoigwe CE, O’Leary L, Nduka J, et al. Factors associated with delirium and cognitive decline following Hip fracture surgery. Bone Joint J. 2020;102-B(12):1675–1681. doi:10.1302/0301-620X.102B12.BJJ-2019-1537.R3
   PubMedGoogle Scholar
• Uribe AA, Bergese SD. What is the ideal combination antiemetic regimen? Best Pract Res Clin Anaesthesiol. 2020;34(4):701–712. doi:10.1016/j.bpa.2020.10.009
   PubMed Web of Science ®Google Scholar
• Kovac AL. Prevention and treatment of postoperative nausea and vomiting. Drugs. 2000;59(2):213–243. doi:10.2165/00003495-200059020-00005
   PubMed Web of Science ®Google Scholar
• Carlisle JB, Stevenson CA. Drugs for preventing postoperative nausea and vomiting. Cochrane Database Syst Rev. 2006;2006(3):CD004125. doi:10.1002/14651858.CD004125.pub2
   PubMedGoogle Scholar
• Gan TJ. Mechanisms underlying postoperative nausea and vomiting and neurotransmitter receptor antagonist-based pharmacotherapy. CNS Drugs. 2007;21(10):813–833. doi:10.2165/00023210-200721100-00003
   PubMed Web of Science ®Google Scholar
• Tricco AC, Soobiah C, Blondal E, et al. Comparative efficacy of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis. BMC Med. 2015;13:136. doi:10.1186/s12916-015-0371-y
   PubMed Web of Science ®Google Scholar
• Yamanaga S, Posselt AM, Freise CE, Kobayashi T, Tavakol M, Kang SM. A single perioperative injection of dexamethasone decreases nausea, vomiting, and pain after laparoscopic donor nephrectomy. J Transplant. 2017;2017:3518103. doi:10.1155/2017/3518103
   PubMedGoogle Scholar
• Yue C, Wei R, Liu Y. Perioperative systemic steroid for rapid recovery in total knee and Hip arthroplasty: a systematic review and meta-analysis of randomized trials. J Orthop Surg Res. 2017;12(1):100. doi:10.1186/s13018-017-0601-4
   PubMedGoogle Scholar
• Mihara T, Ishii T, Ka K, Goto T. Effects of steroids on quality of recovery and adverse events after general anesthesia: meta-analysis and trial sequential analysis of randomized clinical trials. PLoS One. 2016;11(9):e0162961. doi:10.1371/journal.pone.0162961
   PubMed Web of Science ®Google Scholar
• Zhang Y, Leng YF, Xue X, Zhang Y, Wang T, Kang YQ. Effects of penehyclidine hydrochloride in small intestinal damage caused by limb ischemia-reperfusion. World J Gastroenterol. 2011;17(2):254–259. doi:10.3748/wjg.v17.i2.254
   PubMed Web of Science ®Google Scholar