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International Medical Case Reports Journal Volume 17, 2024 - Issue
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Case reports

Report of Two Contrasting Cases of Epstein–Barr Virus–Associated Hemophagocytic Lymphohistiocytosis: Comparison to Infectious Mononucleosis and Flow Cytometric Analysis of Bone Marrow

Shiro OnoDepartment of General Medicine, Nara Medical University, Kashihara, Nara, JapanCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-8956-2725
ORCID Icon,
Kiyomi YoshimotoDepartment of General Medicine, Nara Medical University, Kashihara, Nara, JapanORCID Iconhttps://orcid.org/0000-0001-5823-8239
ORCID Icon,
Masaki MatsubaraDepartment of General Medicine, Nara Medical University, Kashihara, Nara, JapanORCID Iconhttps://orcid.org/0000-0002-6337-3280
ORCID Icon,
Nobushiro NishimuraDepartment of General Medicine, Nara Medical University, Kashihara, Nara, JapanORCID Iconhttps://orcid.org/0000-0001-5163-0481
ORCID Icon,
Hiromasa KawashimaDepartment of General Medicine, Nara Medical University, Kashihara, Nara, JapanORCID Iconhttps://orcid.org/0000-0001-9345-0665
ORCID Icon,
Ryo YoneimaDepartment of General Medicine, Nara Medical University, Kashihara, Nara, JapanORCID Iconhttps://orcid.org/0000-0002-0382-7498
ORCID Icon,
Noritaka YadaDepartment of General Medicine, Nara Medical University, Kashihara, Nara, JapanORCID Iconhttps://orcid.org/0000-0002-8434-7399
ORCID Icon &
Kenji NishioDepartment of General Medicine, Nara Medical University, Kashihara, Nara, JapanORCID Iconhttps://orcid.org/0000-0003-0851-9643
ORCID Icon show all
Pages 43-49 | Received 06 Nov 2023, Accepted 24 Dec 2023, Published online: 20 Jan 2024

References

  • Henter JI, Horne A, Arico M, et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2007;48(2):124–131. doi:10.1002/pbc.21039
  • Ramos-Casals M, Brito-Zerón P, López-Guillermo A, Khamashta MA, Bosch X. Adult haemophagocytic syndrome. Lancet. 2014;383(9927):1503–1516. doi:10.1016/S0140-6736(13)61048-X
  • Riviere S, Galicier L, Coppo P, et al. Reactive hemophagocytic syndrome in adults: a retrospective analysis of 162 patients. Am J Med. 2014;127(11):1118–1125. doi:10.1016/j.amjmed.2014.04.034
  • Li J, Wang Q, Zheng W, et al. Hemophagocytic lymphohistiocytosis: clinical analysis of 103 adult patients. Medicine. 2014;93(2):100–105. doi:10.1097/MD.0000000000000022
  • Kim WY, Montes-Mojarro IA, Fend F, Quintanilla-Martinez L. Epstein-Barr virus-associated T and NK-cell lymphoproliferative diseases. Front Pediatr. 2019;7:71. doi:10.3389/fped.2019.00071
  • Zhao Y, Li Z, Zhang L, et al. Clinical features and outcomes of patients with hemophagocytic lymphohistiocytosis at onset of systemic autoinflammatory disorder and compare with Epstein-Barr virus (EBV)-related hemophagocytic lymphohistiocytosis. Medicine. 2020;99(1):e18503. doi:10.1097/MD.0000000000018503
  • Maakaroun NR, Moanna A, Jacob JT, Albrecht H. Viral infections associated with haemophagocytic syndrome. Rev Med Virol. 2010;20(2):93–105. doi:10.1002/rmv.638
  • Kofteridis D, Valachis A. Mononucleosis and Epstein–Barr virus infection: treatment and medication. Virus Adapt Treat. 2012;23. doi:10.2147/VAAT.S17837
  • Valade S, Joly BS, Veyradier A, et al. Coagulation disorders in patients with severe hemophagocytic lymphohistiocytosis. PLoS One. 2021;16(8):e0251216. doi:10.1371/journal.pone.0251216
  • Park S, Ko YH. Epstein-Barr virus-associated T/natural killer-cell lymphoproliferative disorders. J Dermatol. 2014;41(1):29–39. doi:10.1111/1346-8138.12322
  • Kimura H, Fujiwara S. Overview of EBV-associated T/NK-cell lymphoproliferative diseases. Front Pediatr. 2018;6:417. doi:10.3389/fped.2018.00417
  • Toga A, Wada T, Sakakibara Y, et al. Clinical significance of cloned expansion and CD5 down-regulation in Epstein-Barr Virus (EBV)-infected CD8+ T lymphocytes in EBV-associated hemophagocytic lymphohistiocytosis. J Infect Dis. 2010;201(12):1923–1932. doi:10.1086/652752
  • De Smet MAJ, Bogaert S, Schauwvlieghe A, Dendooven A, Depuydt P, Druwe P. Case report: hemorrhagic fever with renal syndrome presenting as hemophagocytic lymphohistiocytosis. Front Med Lausanne. 2022;9:1096900. doi:10.3389/fmed.2022.1096900

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