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International Medical Case Reports Journal Volume 17, 2024 - Issue
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Case reports

Merkel Cell Carcinoma Masquerading Clinically as a Cyst in a Young Patient

Harty Elouise Ashby1 Department of Pathology, Pikeville Medical Center, Pikeville, KY, USA
,
Grayson N Jones1 Department of Pathology, Pikeville Medical Center, Pikeville, KY, USA
,
Oon Leedhanachoke2 Department of General Surgery, Pikeville Medical Center, Pikeville, KY, USA
,
Phillip Jen3 Department of BioMedical Science, University of Pikeville, Pikeville, KY, USACorrespondence[email protected]
,
Noah Helphenstine3 Department of BioMedical Science, University of Pikeville, Pikeville, KY, USA
&
Fadi Al Akhrass4 Department of Infectious Diseases, Pikeville Medical Center, Pikeville, KY, USA
Pages 289-293 | Received 13 Nov 2023, Accepted 21 Mar 2024, Published online: 04 Apr 2024

References

  • Toker C. Trabecular carcinoma of the skin. Arch Dermatol. 1972;105(1):107–110. doi:10.1001/archderm.1972.01620040075020
  • Albores-Saavedra J, Batich K, Chable-Montero F, et al. Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases: a population based study. J Cutan Pathol. 2009;37:20–27. doi:10.1111/j.1600-0560.2009.01370.x
  • Jacobs D, Huang H, Olino K, et al. Assessment of Age, Period, and Birth Cohort Effects and Trends in Merkel Cell Carcinoma Incidence in the United States. JAMA Dermatol. 2021;157:59–65. doi:10.1001/jamadermatol.2020.4102
  • Paulson K, Youn S, Vandeven N, et al. Merkel cell carcinoma: current US incidence and projected increases based on changing demographics. J Am Acad Dermatol. 2018;78(3):457–463. doi:10.1016/j.jaad.2017.10.028
  • Mistry K, Levell NJ, Hollestein L, et al. Trends in incidence, treatment and survival of Merkel cell carcinoma in England 2004–2018: a cohort study. Br J Dermatol. 2023;188(2):228–236. doi:10.1093/bjd/ljac044
  • SEER*Explorer: an interactive website for SEER cancer statistics [Internet]. Surveillance Research Program, National Cancer Institute. Accessed from: https://seer.cancer.gov/explorer/. Accessed February 2, 2024.
  • Halata Z, Grim M, Bauman KI. Friedrich Sigmund Merkel and his “Merkel cell”, morphology, development, and physiology: review and new results. Anat Rec a Discov Mol Cell Evol Biol. 2003;271:225–239. doi:10.1002/ar.a.10029
  • Uchi H. Merkel cell carcinoma: an update and immunotherapy. Front Oncol. 2018;8:48. doi:10.3389/fonc.2018.00048
  • Winkelmann RK. The Merkel cell system and comparison between it and the neurosecretory or APUD cell system. J Invest Dermatol. 1977;69:41–46. doi:10.1111/1523-1747.ep12497864
  • Harold A, Amako Y, Hachisuka J, et al. Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibition. Proc Natl Acad Sci U S A. 2019;116(40):20104–20114. doi:10.1073/pnas.1907154116
  • Mazziotta C, Cervellera CF, Badiale G. Distinct retinoic gene signatures discriminate Merkel cell polyomavirus-positive from -negative Merkel cell carcinoma cells. J Med Virol. 2023;95(7):e28949. doi:10.1002/jmv.28949
  • Hoefler H, Kerl H, Lackinger E, Helleis G, Denk H. The intermediate filament cytoskeleton of cutaneous neuroendocrine carcinoma (Merkel cell tumour). Immunohistochemical and biochemical analyses. Virchows Arch a Pathol Anat Histopathol. 1985;406:339–350. doi:10.1007/BF00704303
  • Mulchan N, Cayton A, Asarian A, Xiao P. Merkel cell carcinoma: a case report and literature review. J Surg Case Rep. 2019;rjz322. doi:10.1093/jscr/rjz322
  • Leonard JH, Bell JR. Insights into the Merkel cell phenotype from Merkel cell carcinoma cell lines. Australas J Dermatol. 1997;38:S91–S98. doi:10.1111/j.1440-0960.1997.tb01019.x
  • Sauer CM, Haugg AM, Chteinberg E, et al. Reviewing the current evidence supporting early B-cells as the cellular origin of Merkel cell carcinoma. Crit. Rev Oncol Hematol. 2017;116:99–105. doi:10.1016/j.critrevonc.2017.05.009
  • Szeder V, Grim M, Halata Z, Sieber-Blum M. Neural crest origin of mammalian Merkel cells. Dev Biol. 2003;253(2):258–263. doi:10.1016/S0012-1606(02)00015-5
  • Gauci M-L, Aristei C, Becker JC, et al. Diagnosis and treatment of Merkel cell carcinoma: European consensus-based interdisciplinary guideline – update 2022. Eur J Cancer. 2022;171:203–231.
  • Goh G, Walradt T, Markarov V, et al. Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy. Oncotarget. 2016;7(3):3403–3415. doi:10.18632/oncotarget.6494
  • Spurgeon ME, Lambert PF. Merkel cell polyomavirus: a newly discovered human virus with oncogenic potential. Virol. 2013;435(1):118–130. doi:10.1016/j.virol.2012.09.029
  • Howard RA, Dores GM, Curtis RE, Anderson WF, Travis LB. Merkel Cell Carcinoma and Multiple Primary Cancers. Cancer. Epidemiol Biomarkers Prev. 2006;15:1545–1549. doi:10.1158/1055-9965.EPI-05-0895
  • Heath M, Jaimes N, Lemos B, et al. Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. J Am Acad Dermatol. 2008;58(3):375–381. doi:10.1016/j.jaad.2007.11.020

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