Advanced search
Publication Cover
International Medical Case Reports Journal Volume 17, 2024 - Issue
Submit an article Journal homepage
28
Views
0
CrossRef citations to date
0
Altmetric
Case Reports

Successful Treatment of Severe Case of Lipid Overload Syndrome with Pancreatitis and Pneumonia: A Case Report

Zi-Guo Sun1 Department of Intensive Care and Emergency Center, Bazhong Hospital of Integrated Chinese and Western Medicine, Bazhong, Sichuan, 636600, People’s Republic of China;2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaORCID Iconhttps://orcid.org/0009-0001-8996-4628View further author information
ORCID Icon,
Shi-Cheng Xu2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaView further author information
,
Qin Yang3 School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan, 610000, People’s Republic of ChinaView further author information
,
Yun Yao2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaView further author information
,
Qi-Long Mao2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaView further author information
,
Cheng-Feng He2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaView further author information
,
Chang-Jiang Guan2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaView further author information
,
Yan Du2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaView further author information
,
Li Ma2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaView further author information
,
Xie-Shan Huang2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaView further author information
,
Xiao-Long Hou2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaView further author information
,
Hong-Mei Yang2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaView further author information
,
Xia Peng2 Department of Critical Care Medicine, Bazhong Central Hospital, Bazhong, Sichuan, 636600, People’s Republic of ChinaCorrespondence[email protected] [email protected]
View further author information
&
Jun-Jie Jian4 Department of Health Management, Bazhong Center for Health Education and Health Management, Bazhong, Sichuan, 636600, People’s Republic of ChinaView further author information
 show all
Pages 471-477 | Received 15 Feb 2024, Accepted 12 May 2024, Published online: 16 May 2024

References

  • Hojsak I, Kolaček S. Fat overload syndrome after the rapid infusion of SMOFlipid emulsion. JPEN J Parenter Enteral Nutr. 2014;38(1):119–121. doi:10.1177/0148607113482001
  • Brouwer CB, de Bruin TW, Jansen H, Erkelens DW. Different clearance of intravenously administered olive oil and soybean-oil emulsions: role of hepatic lipase. Am J Clin Nutr. 1993;57(4):533–539. doi:10.1093/ajcn/57.4.533
  • Boxhoorn L, Voermans RP, Bouwense SA, et al. Acute pancreatitis. Lancet. 2020;396(10252):726–734. doi:10.1016/S0140-6736(20)31310-6
  • Liu P, Feng Z. Pharmaceutical practices in a case of fat overload syndrome. Strait Pharm J. 2021;33:176–178.
  • Wei Q, Dong D, Yang J, Sun P. A case of fat overload syndrome induced by lipid emulsion. Med J North Chin Milit Med. 2004;2004:350.
  • Schlegelmilch M, Feder J, Creery D. Inadvertent acute lipid injectable emulsion overdose resulting in fat overload syndrome and pancreatitis in a patient with TPN dependence. JPGN Rep. 2022;3(1):e146. doi:10.1097/PG9.0000000000000146
  • Yan Z, Chen L, Qi Y. Literature analysis of adverse reactions induced by lipid emulsion in 97 cases. Chin Pharm. 2010;21:3038–3040.
  • Li C. Report of four fatal cases of fat overload syndrome caused by intravenous infusion of lipid emulsion for the treatment of cerebral hemorrhage. Sichuan Med J. 2000;2000:816–817.
  • Liu W. Analysis of Adverse Reactions and Precautions in the Use of Lipid Emulsion Injection. Heilongjiang Science and Technology Information; 2014:18.
  • Wang X. Study on adverse reactions and precautions in the use of lipid emulsion injection. Med Rev. 2013;19:2471–2473.
  • Bi G, Wang J. A case of fat overload syndrome with chylous blood. Cancer Prevent Treat. 2014;27:60–61.
  • Huang SP, Toh DE, Sue YM, Chen TH, Cheng SW, Cheng CY. Double filtration plasmapheresis in treatment of acute pancreatitis associated with severe hypertriglyceridemia: three case reports. Medicine. 2018;97(44):e12987. doi:10.1097/MD.0000000000012987
  • Kollef MH, McCormack MT, Caras WE, Reddy VV, Bacon D. The fat overload syndrome: successful treatment with plasma exchange. Ann Intern Med. 1990;112(7):545–546. doi:10.7326/0003-4819-112-7-545
  • Anez-Bustillos L, Dao DT, Baker MA, Fell GL, Puder M, Gura KM. Intravenous fat emulsion formulations for the adult and pediatric patient: understanding the differences. Nutr Clin Pract. 2016;31(5):596–609. doi:10.1177/0884533616662996
  • Mthembu SXH, Dludla PV, Nyambuya TM, et al. Experimental models of lipid overload and their relevance in understanding skeletal muscle insulin resistance and pathological changes in mitochondrial oxidative capacity. Biochimie. 2022;196:182–193. doi:10.1016/j.biochi.2021.09.010
  • Moon YS, Chun P, Chung S. Ezetimibe and fenofibrate combination therapy for mixed hyperlipidemia. Drugs Today. 2007;43(1):35–45. doi:10.1358/dot.2007.43.1.1037478
  • Alhomoud IS, Talasaz A, Mehta A, et al. Role of lipoprotein(a) in atherosclerotic cardiovascular disease: a review of current and emerging therapies. Pharmacotherapy. 2023;43(10):1051–1063. doi:10.1002/phar.2851
  • Parhofer KG, Laufs U. The Diagnosis and Treatment of Hypertriglyceridemia. Dtsch Arztebl Int. 2019;116(49):825–832. doi:10.3238/arztebl.2019.0825
  • Ridker PM, Bhatt DL, Pradhan AD, Glynn RJ, MacFadyen JG, Nissen SE. Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy: a collaborative analysis of three randomised trials. Lancet. 2023;401(10384):1293–1301. doi:10.1016/S0140-6736(23)00215-5
  • Liu Y, Zhang J, Yu P, Niu J, Yu S. Mechanisms and efficacy of intravenous lipid emulsion treatment for systemic toxicity from local anesthetics. Front Med. 2021;8:756866. doi:10.3389/fmed.2021.756866

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.