Prevalence and Associated Factors of Anemia Among Hospital Admitted Patients in Eastern Ethiopia

References

• Fonseca C, Araujo M, Moniz P, et al. Prevalence and prognostic impact of anemia and iron deficiency in patients hospitalized in an internal medicine ward: the Pro‐Iron study. Eur J Haematol. 2017;99(6):505–513. doi:10.1111/ejh.12963
   PubMed Web of Science ®Google Scholar
• Alsaeed M, Ahmed S, Seyadi K, Ahmed A, Alawi S, Abulsaad K. The prevalence and impact of anemia in hospitalized older adults: a single center experience from Bahrain. J Taibah Univer Med Sci. 2022;17(4):587–595. doi:10.1016/j.jtumed.2022.02.003
   PubMed Web of Science ®Google Scholar
• Bashir F, Nageen A, Kidwai S, Zulfikar S, Shiraz S, Ara J. Anemia in hospitalized patient: prevalence, etiology and risk factors. J Liaq Univer Med Health Sci. 2017;16:2.
   Google Scholar
• Dovonou C, Alassani A, Attinsounon C, et al. Epidemiology of anemia at the internal medicine department in Borgou Departmental Hospital Center (DHC) in Parakou (Benin). Open J Inter Med. 2018;8(2):123–130. doi:10.4236/ojim.2018.82013
   Google Scholar
• Kuule J, Seremba E, Freers J. Anaemia among patients with congestive cardiac failure in Uganda–its impact on treatment outcomes. South Af Med J. 2009;99(12):876–880.
   PubMed Web of Science ®Google Scholar
• Migone De Amicis M, Poggiali E, Motta I, et al. Anemia in elderly hospitalized patients: prevalence and clinical impact. Intern Emerg Med. 2015;10:581–586. doi:10.1007/s11739-015-1197-5
   PubMed Web of Science ®Google Scholar
• World Health Organization. Nutritional Anaemias: Tools for Effective Prevention and Control. World Health Organization; 2017.
   Google Scholar
• World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. In: Vitamin and Mineral Nutrition Information System. Geneva: World Health Organization; 2011.
   Google Scholar
• Halawi R, Moukhadder H, Taher A. Anemia in the elderly: a consequence of aging? Expert Rev Hematol. 2017;10(4):327–335. doi:10.1080/17474086.2017.1285695
   PubMed Web of Science ®Google Scholar
• Kurniali P, Curry S, Brennan K, et al. A retrospective study investigating the incidence and predisposing factors of hospital-acquired anemia. Anemia. 2014;2014:1–6. doi:10.1155/2014/634582
   Google Scholar
• Chamba C, Nasser A, Mawalla W, et al. Anaemia in the hospitalized elderly in Tanzania: prevalence, Severity, and micronutrient deficiency status. Anemia. 2021;2021:1–6. doi:10.1155/2021/9523836
   Web of Science ®Google Scholar
• Munenguni E, Huda A, Jaffer T, Zimbeiya A, Henke O. Anemia in hospitalized patients in A referral hospital in Northern Tanzania. East Afr Med J. 2021;98:5.
   Google Scholar
• Kassebaum N, Collaborators GA. The global burden of anemia. Hematol Oncol Clin North Am. 2016;30(2):247–308. doi:10.1016/j.hoc.2015.11.002
   PubMed Web of Science ®Google Scholar
• Randi M, Bertozzi I, Santarossa C, et al. Prevalence and causes of anemia in hospitalized patients: impact on diseases outcome. J Clin Med. 2020;9(4):950. doi:10.3390/jcm9040950
   PubMed Web of Science ®Google Scholar
• Girelli D, Marchi G, Camaschella C. Anemia in the elderly. HemaSphere. 2018;2:e40. doi:10.1097/HS9.0000000000000040
   PubMed Web of Science ®Google Scholar
• Weiss G, Goodnough LT. Anemia of chronic disease. New England J Med. 2005;352(10):1011–1023. doi:10.1056/NEJMra041809
   PubMed Web of Science ®Google Scholar
• Busti F, Marchi G, Ugolini S, Castagna A, Girelli D. Anemia and iron deficiency in cancer patients: role of iron replacement therapy. Pharmaceuticals. 2018;11(4):94. doi:10.3390/ph11040094
   Web of Science ®Google Scholar
• Camaschella C. Iron-deficiency anemia. New England J Med. 2015;372(19):1832–1843. doi:10.1056/NEJMra1401038
   PubMed Web of Science ®Google Scholar
• Bekele A, Teji K, Egata G, Gebremichael B. Anemia and associated factors among type-2 diabetes mellitus patients attending public hospitals in Harari Region, Eastern Ethiopia. PLoS One. 2019;14(12):e0225725. doi:10.1371/journal.pone.0225725
   PubMed Web of Science ®Google Scholar
• Wassie M, Aemro A, Fentie B, Khatami F. Prevalence and associated factors of baseline anemia among cervical cancer patients in Tikur Anbesa Specialized Hospital, Ethiopia. BMC Women’s Health. 2021;21(1):1–8. doi:10.1186/s12905-020-01152-w
   PubMed Web of Science ®Google Scholar
• Anderson A. Prevalence of anemia, overweight/obesity, and undiagnosed hypertension and diabetes among residents of selected communities in Ghana. Int J Chronic Dis. 2017;2017:1–7. doi:10.1155/2017/7836019
   Google Scholar
• Elsayid M, Al-Qahtani A, Alanazi A, Qureshi S. Determination of the most common morphological patterns of anemia among Saudi anemic patients attending King Abdul-aziz Medical City-Riyadh. Intern J Med Public Health. 2015;5:4.
   Google Scholar
• Pus A, Moriyama M, Uno M, Rahman MM. Identifying factors of obesity in Papua New Guinea: a descriptive study. Health. 2016;8(14):1616–1629. doi:10.4236/health.2016.814158
   Google Scholar
• Benítez Brito N, Suárez Llanos J, Fuentes Ferrer M, et al. Relationship between mid-upper arm circumference and body mass index in inpatients. PLoS One. 2016;11(8):e0160480. doi:10.1371/journal.pone.0160480
   PubMed Web of Science ®Google Scholar
• World Health Organization. Guidelines on Drawing Blood: Best Practices in Phlebotomy. World Health Organization; 2010.
   Google Scholar
• World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. In: Vitamin and Mineral Nutrition Information System. Document Reference World Health Organization; 2011.
   Google Scholar
• Ahmed K, Danial K, Khurram A, Wasey M, Ahmed M, Jangda Z. To evaluate the renal function deterioration along with other anemia predictors in patients with diabetes mellitus type 2 in Karachi, Pakistan. Pak J Surg. 2017;33(2):135–139.
   Google Scholar
• Geisel T, Martin J, Schulze B, et al. An etiologic profile of anemia in 405 geriatric patients. Anemia. 2014;2014:1–7. doi:10.1155/2014/932486
   Google Scholar
• Röhrig G, Klossok W, Becker I, Benzing T, Schulz R. Prevalence of anemia among elderly patients in an emergency room setting. Eur Geriatr Med. 2014;5(1):3–7. doi:10.1016/j.eurger.2013.10.008
   Web of Science ®Google Scholar
• Awan M, Fazal I, Lodhi M, Azhar R, Anwar A, Tariq M. Frequency of iron deficiency anemia in patients of inflammatory bowel disease at Pak Emirates Military Hospital, Rawalpindi. Pakistan Arme Forces Med J. 2022;72(SUPPL–2):S168–71. doi:10.51253/pafmj.v72iSUPPL-2.2785
   Google Scholar
• Aithal K, Meti K, Jain S. A study of pattern and causes of anaemia in elderly patients admitted at tertiary centre. Sch J Appl Med Sci. 2017;5(4D):1483–1486.
   Google Scholar
• Ashraf A. Frequency of anaemia in patients presenting to a tertiary care hospital in Lahore, Pakistan. Medicine. 2018;4(19):12.
   Google Scholar
• Idris I, Tohid H, Muhammad N, et al. Anaemia among primary care patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD): a multicentred cross-sectional study. BMJ open. 2018;8(12):e025125. doi:10.1136/bmjopen-2018-025125
   PubMed Web of Science ®Google Scholar
• Abdulqadir A, Polus R. Prevalence of anemia of chronic disease and iron deficiency anemia among adult diabetic patients in Erbil City. Zanco J Med Sci. 2014;18:1.
   Google Scholar
• Madu AJ, Ughasoro MD. Anaemia of chronic disease: an in-depth review. Med Princ Pract. 2017;26(1):1–9. doi:10.1159/000452104
   PubMed Web of Science ®Google Scholar
• Paramastri R, Hsu C, Lee H, Lin L, Kurniawan A, Chao J. Association between dietary pattern, lifestyle, anthropometric status, and anemia-related biomarkers among adults: a population-based study from 2001 to 2015. Int J Environ Res Public Health. 2021;18(7):3438. doi:10.3390/ijerph18073438
   PubMed Web of Science ®Google Scholar
• Latvala J, Parkkila S, Niemelä O. Excess alcohol consumption is common in patients with cytopenia: studies in blood and bone marrow cells. Alcohol Clin Exp Res. 2004;28(4):619–624. doi:10.1097/01.ALC.0000122766.54544.3B
   PubMed Web of Science ®Google Scholar
• Yokoyama A, Yokoyama T, Brooks P, et al. Macrocytosis, macrocytic anemia, and genetic polymorphisms of alcohol dehydrogenase‐1 b and aldehyde dehydrogenase‐2 in J apanese Alcoholic Men. Alcohol Clin Exp Res. 2014;38(5):1237–1246. doi:10.1111/acer.12372
   PubMed Web of Science ®Google Scholar
• Colman N, Herbert V. Hematologic complications of alcoholism: overview. Semin Hematol. 1980;17(3):164–176.
   PubMed Web of Science ®Google Scholar
• Lewis G, Wise M, Poynton C, Godkin A. A case of persistent anemia and alcohol abuse. Nat Clin Pract Gastroenterol Hepatol. 2007;4(9):521–526. doi:10.1038/ncpgasthep0922
   PubMedGoogle Scholar
• Kubo S, Hosomi N, Hara N, et al. Ischemic stroke mortality is more strongly associated with anemia on admission than with underweight status. J Stroke Cerebrov Dis. 2017;26(6):1369–1374. doi:10.1016/j.jstrokecerebrovasdis.2017.02.016
   PubMed Web of Science ®Google Scholar
• Aronson D, Nassar M, Goldberg T, Kapeliovich M, Hammerman H, Azzam Z. The impact of body mass index on clinical outcomes after acute myocardial infarction. Int J Cardiol. 2010;145(3):476–480. doi:10.1016/j.ijcard.2009.12.029
   PubMedGoogle Scholar
• Cox S, Makani J, Fulford A, et al. Nutritional status, hospitalization and mortality among patients with sickle cell anemia in Tanzania. haematologica. 2011;96(7):948. doi:10.3324/haematol.2010.028167
   PubMed Web of Science ®Google Scholar
• Loh K, Vriens M, Gerritsen A, et al. Unintentional weight loss is the most important indicator of malnutrition among surgical cancer patients. Neth J Med. 2012;70(8):365–369.
   PubMed Web of Science ®Google Scholar
• Mariette C, De Botton M-L, Piessen G. Surgery in esophageal and gastric cancer patients: what is the role for nutrition support in your daily practice? Ann Surg Oncol. 2012;19:2128–2134. doi:10.1245/s10434-012-2225-6
   PubMed Web of Science ®Google Scholar
• Yanoff L, Menzie C, Denkinger B, et al. Inflammation and iron deficiency in the hypoferremia of obesity. Int J Obes. 2007;31(9):1412–1419. doi:10.1038/sj.ijo.0803625
   PubMed Web of Science ®Google Scholar
• Khan A, Khan W, Ayub M, Humayun M, Haroon M. Ferritin is a marker of inflammation rather than iron deficiency in overweight and obese people. J Obes. 2016;2016:1–7. doi:10.1155/2016/1937320
   Google Scholar
• Arshad M, Jaberian S, Pazouki A, Riazi S, Rangraz M, Mokhber S. Iron deficiency anemia and megaloblastic anemia in obese patients. Rom J Intern Med. 2017;55(1):3–7. doi:10.1515/rjim-2016-0046
   PubMed Web of Science ®Google Scholar
• Aigner E, Feldman A, Datz C. Obesity as an emerging risk factor for iron deficiency. Nutrients. 2014;6(9):3587–3600. doi:10.3390/nu6093587
   PubMed Web of Science ®Google Scholar
• Sal E, Yenicesu I, Celik N, et al. Relationship between obesity and iron deficiency anemia: is there a role of hepcidin? Hematology. 2018;23(8):542–548. doi:10.1080/10245332.2018.1423671
   PubMed Web of Science ®Google Scholar
• Saad R, Qutob H. The relationship between anemia and obesity. Expert Rev Hematol. 2022;15(10):911–926. doi:10.1080/17474086.2022.2131521
   PubMed Web of Science ®Google Scholar
• Thakur N, Chandra J, Pemde H, Singh V. Anemia in severe acute malnutrition. Nutrition. 2014;30(4):440–442. doi:10.1016/j.nut.2013.09.011
   PubMed Web of Science ®Google Scholar
• van Bokhorst-de van der Schueren M. Nutritional support strategies for malnourished cancer patients. Europ J Oncol Nurs. 2005;9:S74–S83.
   PubMedGoogle Scholar
• Tseng F, Gou G, Wang S, Shyu J, Pan R. Chronic liver disease and cirrhosis increase morbidity in geriatric patients treated surgically for Hip fractures: analysis of the US Nationwide Inpatient Sample. BMC Geriatr. 2022;22(1):150. doi:10.1186/s12877-022-02832-y
   PubMed Web of Science ®Google Scholar
• Rauf A, Gupta V, Bansal R, et al. Anemia profile in patients of chronic liver disease from North Indian tertiary hospital. J Clin Exp Hepatol. 2014;4:S41–S2.
   Google Scholar
• Nuruddin A, Sultana A, Akter F, Ahmed E, Dutta B. Prevalence and pattern of anemia among the hospitalized patients of chronic liver disease in a tertiary care hospital. J Chittagong Med Coll Teach Assoc. 2017;28(2):111–115. doi:10.3329/jcmcta.v28i2.62433
   Google Scholar
• Farrell G, Larter C. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology. 2006;43(S1):S99–S112. doi:10.1002/hep.20973
   PubMed Web of Science ®Google Scholar
• Gkamprela E, Deutsch M, Pectasides D. Iron deficiency anemia in chronic liver disease: etiopathogenesis, diagnosis and treatment. Anna Gastroenterol. 2017;30(4):405. doi:10.20524/aog.2017.0152
   PubMed Web of Science ®Google Scholar
• Stauffer M, Fan T. Prevalence of anemia in chronic kidney disease in the United States. PLoS One. 2014;9(1). doi:10.1371/journal.pone.0084943
   Web of Science ®Google Scholar
• Lee Y, Chang Y, Kang J, et al. Risk factors for incident anemia of chronic diseases: a cohort study. PLoS One. 2019;14:5.
   Google Scholar
• Suega K, Bakta M, Dharmayudha TG, Lukman J, Suwitra K. Profile of anemia in chronic renal failure patients: comparison between predialyzed and dialyzed patients at the division of nephrology, department of internal medicine, Sanglah Hospital, Denpasar, Bali, Indonesia. Dep Intern Med Sanglah Hosp Denpasar Bali Indonesia Inflam. 2005;1:6–9.
   Google Scholar
• Khan A, Afridi M, Ali G, Idrees M, Waqas M. Prevalence of anemia in chronic kidney disease patients in Lady Reading Hospital, Peshawar. Khyber J Med Sci. 2018;11:439–442.
   Google Scholar
• Amoako Y, Laryea D, Bedu-Addo G, Andoh H, Awuku Y. Clinical and demographic characteristics of chronic kidney disease patients in a tertiary facility in Ghana. Pan Afr Med J. 2014;2014:18.
   Google Scholar
• Donnelly S. Why is erythropoietin made in the kidney? The kidney functions as a critmeter. Am J Kid Dis. 2001;38(2):415–425. doi:10.1053/ajkd.2001.26111
   PubMed Web of Science ®Google Scholar
• Ryu S, Park S, Jung J, et al. The prevalence and management of anemia in chronic kidney disease patients: result from the Korean cohort study for outcomes in patients with chronic kidney disease (KNOW-CKD). J Korean Med Sci. 2017;32(2):249–256. doi:10.3346/jkms.2017.32.2.249
   PubMed Web of Science ®Google Scholar
• Feng L, Xu L, Yuan W, Xu Z, Feng Z, Zhang H. Preoperative anemia and total hospitalization time are the independent factors of preoperative deep venous thromboembolism in Chinese elderly undergoing Hip surgery. BMC Anesthesiol. 2020;20:1–6. doi:10.1186/s12871-020-00983-2
   PubMed Web of Science ®Google Scholar
• Xiong X, Xu S, Li T, Cheng B. Correlation of the severity of anemia in patients undergoing total joint arthroplasty with preoperative deep vein thrombosis: a retrospective cohort study. J Orthop Surg Res. 2022;17(1):1–9. doi:10.1186/s13018-021-02689-8
   PubMed Web of Science ®Google Scholar
• Hung S-H, Lin H-C, Chung S-D. Association between venous thromboembolism and iron-deficiency anemia: a population-based study. Blood Coagul Fibrinol. 2015;26(4):368–372. doi:10.1097/MBC.0000000000000249
   PubMed Web of Science ®Google Scholar
• Lecouffe-Desprets M, Néel A, Graveleau J, et al. Venous thromboembolism related to warm autoimmune hemolytic anemia: a case–control study. Autoimmun Rev. 2015;14(11):1023–1028. doi:10.1016/j.autrev.2015.07.001
   PubMed Web of Science ®Google Scholar
• Fall A, Proulle V, Sail A, et al. Risk factors for thrombosis in an African population. Clin Med Insig. 2014;7:S13401.
   Google Scholar
• Goodnough L, Price T, Parvin C, et al. Erythropoietin response to anaemia is not altered by surgery or recombinant human erythropoietin therapy. Br J Haematol. 1994;87(4):695–699. doi:10.1111/j.1365-2141.1994.tb06725.x
   PubMed Web of Science ®Google Scholar
• Lippi G, Franchini M, Favaloro E. Thrombotic complications of erythropoiesis-stimulating agents. In: Seminars in Thrombosis and Hemostasis. © Thieme Medical Publishers; 2010.
   Google Scholar
• Meidani M, Rezaei F, Maracy M, Avijgan M, Tayeri K. Prevalence, severity, and related factors of anemia in HIV/AIDS patients. J Res Med Sci. 2012;17(2):138.
   PubMed Web of Science ®Google Scholar
• Bate A, Kimbi H, Lum E, et al. Malaria infection and anaemia in HIV-infected children in Mutengene, Southwest Cameroon: a cross sectional study. BMC Infect Dis. 2016;16(1):1–9. doi:10.1186/s12879-016-1853-z
   PubMedGoogle Scholar
• Sahle T, Yemane T, Gedefaw L. Effect of malaria infection on hematological profiles of people living with human immunodeficiency virus in Gambella, southwest Ethiopia. BMC Hematol. 2017;17:1–8. doi:10.1186/s12878-017-0072-1
   PubMedGoogle Scholar
• White N. Anaemia and malaria. Malar J. 2018;17(1):1–17.
   PubMedGoogle Scholar
• Spottiswoode N, Duffy P, Drakesmith H. Iron, anemia and hepcidin in malaria. Front Pharmacol. 2014;5:125. doi:10.3389/fphar.2014.00125
   PubMed Web of Science ®Google Scholar
• Minchella P, Armitage A, Darboe B, et al. Elevated hepcidin is part of a complex relation that links mortality with iron homeostasis and anemia in men and women with HIV infection. J Nutr. 2015;145(6):1194–1201. doi:10.3945/jn.114.203158
   PubMed Web of Science ®Google Scholar
• Redig A, Berliner N. Pathogenesis and clinical implications of HIV-related anemia in 2013. Hematology. 2013;2013(1):377–381. doi:10.1182/asheducation-2013.1.377
   PubMed Web of Science ®Google Scholar
• Papathakis P, Piwoz E. Nutrition and Tuberculosis: a review of the literature and considerations for TB control programs. United States agency for international development. Africa’s Health. 2010;2008:1.
   Google Scholar
• Krishnapillai A, Omar M, Ariaratnam S, et al. The prevalence of anemia and its associated factors among older persons: findings from the National Health and Morbidity Survey (NHMS) 2015. Int J Environ Res Public Health. 2022;19(9):4983. doi:10.3390/ijerph19094983
   PubMed Web of Science ®Google Scholar
• Gaspar B, Sharma P, Das R. Anemia in malignancies: pathogenetic and diagnostic considerations. Hematology. 2015;20(1):18–25. doi:10.1179/1607845414Y.0000000161
   PubMed Web of Science ®Google Scholar
• Burney S, Farooq M, Alvi A. Anemia in elderly hospitalized patients: frequency and association with comorbidities 1 2 3. J Islamic Inter Med Coll. 2018;13(4):194–199.
   Google Scholar
• Lechner K, Obermeier H. Cancer-related microangiopathic hemolytic anemia: clinical and laboratory features in 168 reported cases. Medicine. 2012;91(4):195–205. doi:10.1097/MD.0b013e3182603598
   PubMed Web of Science ®Google Scholar