455
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

In vitro Anti-Leishmanial Activities of Methanol Extract of Brucea antidysenterica J.F. Mill Seeds and Its Solvent Fractions

ORCID Icon, ORCID Icon, , ORCID Icon, & ORCID Icon
Pages 123-135 | Received 01 Dec 2022, Accepted 02 Mar 2023, Published online: 13 Mar 2023

References

  • Seid A, Gadisa E, Tsegaw T, et al. Risk map for cutaneous leishmaniasis in Ethiopia based on environmental factors as revealed by geographical information systems and statistics. Geospat Health. 2014;8(2):377–387. doi:10.4081/gh.2014.27
  • Gebremichael D. Zoonotic impact and epidemiological changes of leishmaniasis in Ethiopia. Open Vet J. 2018;8(4):432–440. doi:10.4314/ovj.v8i4.13
  • Hailu A, Gramiccia M, Kager PA. Visceral leishmaniasis in Aba-Roba, south-western Ethiopia: prevalence and incidence of active and subclinical infections. Ann Trop Med Parasitol. 2009;103(8):659–670. doi:10.1179/000349809X12554106963555
  • Sundar S, Chakravarty J. Liposomal Amphotericin B and Leishmaniasis: dose and Response. J Glob Infect Dis. 2010;2. doi:10.4103/0974-777X.62886
  • An I, Harman M, Esen M, Çelik H. The effect of pentavalent antimonial compounds used in the treatment of cutaneous leishmaniasis on hemogram and biochemical parameters. Cutan Ocul Toxicol. 2019;38(3):294–297. doi:10.1080/15569527.2019.1610887
  • Id S, Miguel J, Id P, et al. Topical paromomycin for New World cutaneous leishmaniasis. PLoS Negl Trop Dis. 2019;1–12.
  • Sunyoto T, Potet J, Boelaert M. Why miltefosine — a life-saving drug for leishmaniasis — is unavailable to people who need it the most. BMJ Global Health. 2018:1–10. DOI:10.1136/bmjgh-2018-000709
  • Priscilla E, Gadelha N, Augusto J, et al. Patients with cutaneous leishmaniasis caused by L. guyanensis: a pilot study *. Anais brasileiros de dermatologia. 2015;90(6):807–813. doi:10.1590/abd1806-4841.20153956
  • Hendrickx S, Guerin PJ, Caljon G, Croft SL, Maes L. Evaluating drug resistance in visceral leishmaniasis: the challenges. Parasitology. 2018;145(4):453–463. doi:10.1017/S0031182016002031
  • Nagle AS, Khare S, Kumar AB, et al. Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis. Cheml Rev. 2014;114(22):11305–11347.
  • Tariku Nefo D. Isolation and structural elucidation of an alkaloid constituent from the berries of brucea antidysenterica. Chem Process Eng Res. 2019. 59:13–14. doi:10.7176/CPER
  • Jansen PCM. Spices, Condiments and Medicinal Plants in Ethiopia, Their Taxonomy and Agricultural Significance. Wageningen University and Research; 1981.
  • Tesfaye S, Belete A, Engidawork E, Gedif T, Asres K. Ethnobotanical study of medicinal plants used by traditional healers to treat cancer-like symptoms in Eleven Districts, Ethiopia. Evid Based Complement Alternat Med. 2020;2020:1–23. doi:10.1155/2020/7683450
  • Van Wyk BE. A review of African medicinal and aromatic plants. Med Arom Plants World Afr. 2017;3:19–60. doi:10.1007/978-94-024-1120-1
  • Wubetu M, Abula T, Dejenu G, Freetly HC. Ethnopharmacologic survey of medicinal plants used to treat human diseases by traditional medical practitioners in Dega Damot district, Amhara, Northwestern. BMC Res Notes. 2017;10(1):1–13. doi:10.1186/s13104-017-2482-3
  • Avigdor E, Wohlmuth H, Asfaw Z, Awas T. The current status of knowledge of herbal medicine and medicinal plants in Fiche, Ethiopia The current status of knowledge of herbal medicine and medicinal plants in Fiche, Ethiopia. J Ethnobiol Ethnomed. 2014;10. doi:10.1186/1746-4269-10-38
  • Asnake S, Teklehaymanot T, Hymete A, Erko B, Giday M. Survey of medicinal plants used to treat malaria by sidama people of Boricha District, Sidama Zone, South Region of Ethiopia. Evid Based Complement Alternat Med. 2016;2016. doi:10.1155/2016/9690164
  • Teklehaymanot T, Giday M, Medhin G, Mekonnen Y. Knowledge and use of medicinal plants by people around Debre Libanos monastery in Ethiopia. J Ethnopharmacol. 2006. doi:10.1016/j.jep.2006.11.019
  • Shakila R, Narihiko F, Masayoshi O, Kiyoshi T, Kuo-Hsiung L. Anti-tuberculosis activity of quassinoids. Chem Pharm Bull. 1997;45(9):1527–1529. doi:10.1248/cpb.45.1527
  • Gillin FD, Reiner DS, Suffness M. Bruceantin, a Potent Amoebicide from a Plant, Brucea antidysenterica. Antimicrob Agents Chemoth. 1982;22(2):342–345. doi:10.1128/AAC.22.2.342
  • Kefe A, Giday M, Mamo H, Erko B. Antimalarial properties of crude extracts of seeds of Brucea antidysenterica and leaves of Ocimum lamiifolium. BMC Complement Altern Med. 2016;16:1–8. doi:10.1186/s12906-016-1098-9
  • Zewdie KA, Bhoumik D, Wondafrash DZ. Evaluation of in-vivo antidiarrhoeal and in- vitro antibacterial activities of the root extract of Brucea antidysenterica J. F. Mill (Simaroubaceae). BMC Complement Med Ther. 2020;7:1–11.
  • Tessema Z, Makonnen E, Debella A, Molla Y. Evaluation of in vivo wound healing and anti-inflammatory activity of crude extract of the fruits of Brucea antidysentrica in mice. Biochem Pharmacol. 2018. doi:10.1016/j.wndm.2018.05.005
  • Toma A, Makonnen E, Mekonnen Y, Debella A, Adisakwattana S. Antidiabetic activities of aqueous ethanol and n-butanol fraction of Moringa stenopetala leaves in streptozotocin-induced diabetic rats. BMC Complement Altern Med. 2015:1–8. DOI:10.1186/s12906-015-0779-0
  • Activity A, Profile T, van der A DL, Verschuren WMM, Hendriks HFJ, Beulens JWJ. NPC natural product communications. Am J Clin Nutr. 2010;91(6):1777–1783. doi:10.3945/ajcn.2010.29170
  • Manuscript A. NIH public access; 2009: 1–10. doi:10.1002/9780471729259.mca04es11.Growth.
  • Zhang X, Goncalves R, Mosser DM. The isolation and characterization of murine macrophages. Curr Protoc Immunol. 2008:1–14. DOI:10.1002/0471142735.im1401s83
  • Abeje F, Bisrat D, Hailu A, Asres K. Phytochemistry and antileishmanial activity of the leaf latex of aloe calidophila reynolds. Phytother Res. 2014;1805:1801–1805.
  • Zohra M, Fawzia A. Hemolytic activity of different herbal extracts used in Algeria. Int J Pharm Sci Res. 2014;5(08):495–500.
  • Chan SM, Khoo KS, Sit NW. Interactions between plant extracts and cell viability indicators during cytotoxicity testing: implications for ethnopharmacological studies. Trop J Pharm Res. 2015;14:1991–1998.
  • Leishmania A, Nigussie D, Tasew G, et al. In-vitro investigation of fractionated extracts of Albizia gummifera seed. J Clin Cell Immunol. 2015;6(6). doi:10.4172/2155-9899.1000373
  • Afrin F, Chouhan G, Islamuddin M, Want MY, Ozbak HA, Hemeg HA. Cinnamomum cassia exhibits antileishmanial activity against Leishmania donovani infection in vitro and in vivo. PLoS Negl Trop Dis. 2019;13(5):1–28.
  • Tadele M, Abay SM, Makonnen E, Hailu A. Leishmania donovani growth inhibitors from pathogen box compounds of medicine for malaria venture. Drug Design Dev Ther. 2020;14:1307–1317. doi:10.2147/DDDT.S244903
  • Utaile M, Kassahun A, Abebe T, Hailu A. Experimental parasitology susceptibility of clinical isolates of Leishmania aethiopica to miltefosine, paromomycin, amphotericin B and sodium stibogluconate using amastigote-macrophage in vitro model. Exp Parasitol. 2013;134(1):68–75. doi:10.1016/j.exppara.2013.01.022
  • Berry SL, Hameed H, Thomason A, et al. Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays. PLoS Negl Trop Dis. 2018;12(7):1–20.
  • Nigatu H, Belay A, Ayalew H, et al. In vitro antileishmanial activity of some Ethiopian medicinal plants. J Exper Pharmacol. 2021;Volume 13:15–22. doi:10.2147/JEP.S285079
  • Ajanal M, Gundkalle MB, Nayak SU. Estimation of total alkaloid in Chitrakadivati by UV - Spectrophotometer. Anc Sci Life. 2018;31(4):2–5. doi:10.4103/0257-7941.107361
  • Ehata MT, Phuati AM, Lumpu SN, et al. In vitro antiprotozoal and cytotoxic activity of the aqueous extract, the 80 % methanol extract and its fractions from the seeds of brucea sumatrana Roxb. (Simaroubaceae) growing in democratic Republic of Congo. Chin Med. 2012;2012:65–71. doi:10.4236/cm.2012.31011
  • De Muylder G, Ang KKH, Chen S, Arkin MR, Engel JC, James H. A screen against leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit. PLoS Neglect Trop Dis. 2011;5(7). doi:10.1371/journal.pntd.0001253
  • Gupta S. Visceral leishmaniasis: experimental models for drug discovery. Indian J Med Res. 2011;133:27–39.
  • Aulner N, Danckaert A, Rouault-hardoin E, et al. High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery. To cite this version: HAL Id: pasteur-01433415 High Content Analysis of Primary Macrophages Hosting Proliferatin. Methods Mol Biol. 2017;1535:173–195. doi:10.1371/journal.pntd.0002154
  • Indrayanto G, Putra GS, Suhud F. Validation of in-vitro Bioassay Methods: Application in Herbal Drug Research. 1st ed. Elsevier Inc; 2020. doi:10.1016/bs.podrm.2020.07.005
  • Khoddami A, Wilkes MA, Roberts TH. Techniques for analysis of plant phenolic compounds. Molecules. 2013;18(2):2328–2375. doi:10.3390/molecules18022328
  • Monzote L, Córdova WHP, García M, Piñón A, Setzer WN. In-vitro and in-vivo activities of phenolic compounds against cutaneous in-vitro and in-vivo activities of phenolic compounds against cutaneous Leishmaniasis. Rec Nat Prod. 2016;10(3):269.
  • Antwi CA, Mmalebna C, Id A, et al. In vitro activity and mode of action of phenolic compounds on Leishmania donovani. PLOS Negl Trop Dis. 2019;13(2):1–22.
  • Silva-silva JV, Moragas-tellis CJ. Antileishmanial activity of flavones- rich fraction from Arrabidaea chica Verlot (Bignoniaceae). Front Pharmacol. 2021;12:(July):1–14. doi:10.3389/fphar.2021.703985
  • De Arias AR, Pandolfi E, Celeste M, Rolón M. Selected natural and synthetic phenolic compounds with antileishmanial activity: a five-year review. Curr Bioact Compd. 2012. doi:10.2174/1573407211208040002
  • Liu J, Jin H, Zhang W, Yan S, Shen Y. Chemical constituents of plants from the Genus Brucea. Chem Biodivers. 2009;6:57–70.
  • Ferreira ME, Arias De AR, De Ortiz ST, Inchausti A, Nakayama H. Leishmanicidal acti v ity of two canthin-6-one alkaloids, two major constituents of Zanthoxylum chiloperone v ar. angustifolium. J Ethnopharmacol. 2002;80:7–10.
  • Ju-ichi M, Lee KH, Martin MS, Kempczinski RF, Gordon RD. Antitumor agents, 79. cytotoxic antileukemic alkaloids from. J Vasc Surg. 1986;4(3):428–434.
  • Gabriel RS, Garcia AR, Alviano CS, et al. β -Carboline-1-propionic acid alkaloid: antileishmanial and cytotoxic effects. Turkish J Pharma Sci. 2019;29:755–762.
  • Makong YS, Mouth G, Liliane J, et al. Cytotoxic stilbenes and canthinone alkaloids from Brucea antidysenterica (Simaroubaceae). Molecules. 2019 24(23):1–10.
  • Ehata MT, Lumpu SN, Munduku CK, Kabangu OK, Cos P, Maes L. Study of antiparasitic and cytotoxicity of the aqueous, the 80 % methanol extract and its fractions, and the acute toxicity of the aqueous extract of Brucea sumatrana (Simaroubaceae) leaves collected in mai-ndombe, democratic Republic of Congo. Chin Med. 2016;50(7):93–109. doi:10.4236/cm.2016.73011