Opioid Receptor Mu 1 Gene (OPRM1) A118G Polymorphism and Emotional Modulation of Pain

References

• Potvin S, Marchand S. Pain facilitation and pain inhibition during conditioned pain modulation in fibromyalgia and in healthy controls. Pain. 2016;157(8):1704–1710. doi:10.1097/j.pain.0000000000000573
   PubMed Web of Science ®Google Scholar
• Pielsticker A, Haag G, Zaudig M, Lautenbacher S. Impairment of pain inhibition in chronic tension-type headache. Pain. 2005;118(1):215–223. doi:10.1016/j.pain.2005.08.019
   PubMed Web of Science ®Google Scholar
• Jensen KB, Kosek E, Petzke F, et al. Evidence of dysfunctional pain inhibition in Fibromyalgia reflected in rACC during provoked pain. Pain. 2009;144(1):95–100. doi:10.1016/j.pain.2009.03.018
   PubMed Web of Science ®Google Scholar
• Rhudy JL, Meagher MW. The role of emotion in pain modulation. Curr Opin Psychiatry. 2001;14(3):241–245. doi:10.1097/00001504-200105000-00012
   Web of Science ®Google Scholar
• Rhudy JL. Emotional modulation of pain. In: Neuroscience of Pain, Stress, and Emotion. Elsevier; 2016:51–75.
   Google Scholar
• Rhudy JL, Williams AE, McCabe KM, Russell JL, Maynard LJ. Emotional control of nociceptive reactions (ECON): do affective valence and arousal play a role? Pain. 2008;136(3):250–261. doi:10.1016/j.pain.2007.06.031
   PubMed Web of Science ®Google Scholar
• Rhudy JL, Williams AE, McCabe KM, Rambo PL, Russell JL. Emotional modulation of spinal nociception and pain: the impact of predictable noxious stimulation. Pain. 2006;126(1–3):221–233. doi:10.1016/j.pain.2006.06.027
   PubMed Web of Science ®Google Scholar
• Rhudy JL, Williams AE, McCabe KM, Nguyê˜n MATV, Rambo P. Affective modulation of nociception at spinal and supraspinal levels. Psychophysiology. 2005;42(5):579–587. doi:10.1111/j.1469-8986.2005.00313.x
   PubMed Web of Science ®Google Scholar
• Rhudy JL, Bartley EJ, Williams AE, et al. Are there sex differences in affective modulation of spinal nociception and pain? J Pain. 2010;11(12):1429–1441. doi:10.1016/j.jpain.2010.04.003
   PubMed Web of Science ®Google Scholar
• Roy M, Piché M, Chen J-I, Peretz I, Rainville P. Cerebral and spinal modulation of pain by emotions. Nat Precedings. 2009;2009;1.
   Google Scholar
• Bagley EE, Ingram SL. Endogenous opioid peptides in the descending pain modulatory circuit. Neuropharmacology. 2020;173:108131. doi:10.1016/j.neuropharm.2020.108131
   PubMed Web of Science ®Google Scholar
• Van Ree JM, Niesink RJM, Van Wolfswinkel L, et al. Endogenous opioids and reward. Eur J Pharmacol. 2000;405(1):89–101. doi:10.1016/S0014-2999(00)00544-6
   PubMed Web of Science ®Google Scholar
• Masih J, Verbeke W. Exploring association of opioid receptor genes polymorphism with positive and negative moods using Positive and Negative Affective States Scale (PANAS). Clin Exp Psychol. 2019;5(1):1–6.
   Google Scholar
• Kasai S, Ikeda K. Pharmacogenomics of the human µ-opioid receptor. Pharmacogenomics. 2011;12(9):1305–1320. doi:10.2217/pgs.11.68
   PubMed Web of Science ®Google Scholar
• Peciña M, Love T, Stohler CS, Goldman D, Zubieta J-K. Effects of the mu opioid receptor polymorphism (OPRM1 A118G) on pain regulation, placebo effects and associated personality trait measures. Neuropsychopharmacology. 2015;40(4):957–965. doi:10.1038/npp.2014.272
   PubMed Web of Science ®Google Scholar
• Zubieta JK, Smith YR, Bueller JA, et al. Regional mu opioid receptor regulation of sensory and affective dimensions of pain. Science. 2001;293(5528):311–315. doi:10.1126/science.1060952
   PubMed Web of Science ®Google Scholar
• Perry M, Baumbauer K, Young EE, Dorsey SG, Taylor JY, Starkweather AR. The influence of race, ethnicity and genetic variants on postoperative pain intensity: an integrative literature review. Pain Manage Nurs. 2019;20(3):198–206. doi:10.1016/j.pmn.2018.11.002
   PubMed Web of Science ®Google Scholar
• Hawn SE, Overstreet C, Stewart KE, Amstadter AB. Recent advances in the genetics of emotion regulation: a review. Curr Opin Psychol. 2015;3:108–116. doi:10.1016/j.copsyc.2014.12.014
   PubMedGoogle Scholar
• Daniel AM, Rushing BG, Tapia Menchaca KY. Variation of the human mu-opioid receptor (OPRM1) gene predicts vulnerability to frustration. Sci Rep. 2020;10(1):1–8. doi:10.1038/s41598-020-78783-4
   PubMed Web of Science ®Google Scholar
• Troisi A, Frazzetto G, Carola V, et al. Social hedonic capacity is associated with the A118G polymorphism of the mu-opioid receptor gene (OPRM1) in adult healthy volunteers and psychiatric patients. Soc Neurosci. 2011;6(1):88–97. doi:10.1080/17470919.2010.482786
   PubMed Web of Science ®Google Scholar
• Way BM, Taylor SE, Eisenberger NI. Variation in the mu-opioid receptor gene (OPRM1) is associated with dispositional and neural sensitivity to social rejection. Proc Natl Acad Sci USA. 2009;106(35):15079–15084. doi:10.1073/pnas.0812612106
   PubMed Web of Science ®Google Scholar
• Tan EC, Lim EC, Teo YY, Lim Y, Law HY, Sia AT. Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for post-operative pain. Molecular Pain. 2009;5:32. doi:10.1186/1744-8069-5-32
   PubMed Web of Science ®Google Scholar
• Kolesnikov Y, Gabovits B, Levin A, et al. Chronic pain after lower abdominal surgery: do catechol-O-methyl transferase/opioid receptor μ-1 polymorphisms contribute? Molecular Pain. 2013;9(1):19. doi:10.1186/1744-8069-9-19
   PubMedGoogle Scholar
• Frangakis SG, MacEachern M, Akbar TA, et al. Association of genetic variants with postsurgical pain: a systematic review and meta-analyses. Anesthesiology. 2023;139(6):827–839. doi:10.1097/ALN.0000000000004677
   PubMedGoogle Scholar
• Palit S, Sheaff RJ, France CR, et al. Serotonin transporter gene (5-HTTLPR) polymorphisms are associated with emotional modulation of pain but not emotional modulation of spinal nociception. Biol Psychol. 2011;86(3):360–369. doi:10.1016/j.biopsycho.2011.01.008
   PubMed Web of Science ®Google Scholar
• Rhudy JL, France CR. Defining the nociceptive flexion reflex (NFR) threshold in human participants: a comparison of different scoring criteria. Pain. 2007;128(3):244–253. doi:10.1016/j.pain.2006.09.024
   PubMed Web of Science ®Google Scholar
• Lang PJ, Bradley MM, Cuthbert BN International affective picture system (IAPS): affective ratings of pictures and instruction manual. Technical Report A-6. University of Florida, Gainesville, FL; 2005.
   Google Scholar
• Bradley MM, Lang PJ. Measuring emotion: the self-assessment manikin and the semantic differential. J Behav Ther Exp Psychiatry. 1994;25(1):49–59. doi:10.1016/0005-7916(94)90063-9
   PubMed Web of Science ®Google Scholar
• Harvard. Ethanol precipitation of RNA/DNA; n.d. Available from: https://projects.iq.harvard.edu/files/hlalab/files/ethanol-precipitation-of-rna_hla.pdf. Accessed January 25, 2024.
   Google Scholar
• Ittisoponpisan S, Islam SA, Khanna T, Alhuzimi E, David A, Sternberg MJE. Can predicted protein 3D structures provide reliable insights into whether missense variants are disease associated? J Mol Biol. 2019;431(11):2197–2212. doi:10.1016/j.jmb.2019.04.009
   PubMed Web of Science ®Google Scholar
• Adzhubei IA, Schmidt S, Peshkin L, et al. A method and server for predicting damaging missense mutations. Nature Methods. 2010;7(4):248–249. doi:10.1038/nmeth0410-248
   PubMed Web of Science ®Google Scholar
• DelVentura JL, Terry EL, Bartley EJ, Rhudy JL. Emotional modulation of pain and spinal nociception in persons with severe insomnia symptoms. Ann Behav Med. 2014;47(3):303–315. doi:10.1007/s12160-013-9551-1
   PubMed Web of Science ®Google Scholar
• Palit S, Kerr KL, Kuhn BL, et al. Examining emotional modulation of pain and spinal nociception in native Americans: a preliminary investigation. Int J Psychophysiol. 2013;90(2):272–281. doi:10.1016/j.ijpsycho.2013.08.009
   PubMed Web of Science ®Google Scholar
• Rhudy JL, DelVentura JL, Terry EL, et al. Emotional modulation of pain and spinal nociception in fibromyalgia. PAIN^®. 2013;154(7):1045–1056. doi:10.1016/j.pain.2013.03.025
   PubMed Web of Science ®Google Scholar
• Terry EL, DelVentura JL, Bartley EJ, Vincent AL, Rhudy JL. Emotional modulation of pain and spinal nociception in persons with major depressive disorder (MDD). PAIN^®. 2013;154(12):2759–2768. doi:10.1016/j.pain.2013.08.009
   PubMed Web of Science ®Google Scholar
• Palit S, Williams A, Rhudy J, et al. Further validation of the Emotional Controls (ECON) paradigm: what types of emotional picture contents best modulate pain and nociception? J Pain. 2009;10(4):S26. doi:10.1016/j.jpain.2009.01.114
   Google Scholar
• Seara-Cardoso A, Sebastian C, Viding E, Roiser J. Affective resonance in response to others’ emotional faces varies with affective ratings and psychopathic traits in amygdala and anterior insula. Soc Neurosci. 2015;11:1–13. doi:10.1080/17470919.2015.1029593
   PubMed Web of Science ®Google Scholar
• Lapate RC, Lee H, Salomons TV, van Reekum CM, Greischar LL, Davidson RJ. Amygdalar function reflects common individual differences in emotion and pain regulation success. J Cognitive Neurosci. 2012;24(1):148–158. doi:10.1162/jocn_a_00125
   PubMed Web of Science ®Google Scholar
• Saga Y, Ruff CC, Tremblay L. Disturbance of approach-avoidance behaviors in non-human primates by stimulation of the limbic territories of basal ganglia and anterior insula. Eur J Neurosci. 2019;49(5):687–700. doi:10.1111/ejn.14201
   PubMed Web of Science ®Google Scholar
• Haaranen M, Scuppa G, Tambalo S, et al. Anterior insula stimulation suppresses appetitive behavior while inducing forebrain activation in alcohol-preferring rats. Transl Psychiatry. 2020;10(1):150. doi:10.1038/s41398-020-0833-7
   PubMed Web of Science ®Google Scholar
• Veinante P, Yalcin I, Barrot M. The amygdala between sensation and affect: a role in pain. J Mol Psychiatry. 2013;1(1):9. doi:10.1186/2049-9256-1-9
   PubMedGoogle Scholar
• Quirarte GL, Galvez R, Roozendaal B, McGaugh JL. Norepinephrine release in the amygdala in response to footshock and opioid peptidergic drugs. Brain Res. 1998;808(2):134–140. doi:10.1016/S0006-8993(98)00795-1
   PubMed Web of Science ®Google Scholar
• Leknes S, Tracey I. A common neurobiology for pain and pleasure. Nat Rev Neurosci. 2008;9(4):314–320. doi:10.1038/nrn2333
   PubMed Web of Science ®Google Scholar
• Coolen LM, Fitzgerald ME, Yu L, Lehman MN. Activation of μ opioid receptors in the medial preoptic area following copulation in male rats. Neuroscience. 2004;124(1):11–21. doi:10.1016/j.neuroscience.2003.10.045
   PubMed Web of Science ®Google Scholar
• Bartley EJ, Fillingim RB. Sex differences in pain: a brief review of clinical and experimental findings. Br J Anaesth. 2013;111(1):52–58. doi:10.1093/bja/aet127
   PubMed Web of Science ®Google Scholar
• Hasvik E, Iordanova Schistad E, Grøvle L, Julsrud Haugen A, Røe C, Gjerstad J. Subjective health complaints in patients with lumbar radicular pain and disc herniation are associated with a sex - OPRM1 A118G polymorphism interaction: a prospective 1-year observational study. BMC Musculoskelet Disord. 2014;15(1):161. doi:10.1186/1471-2474-15-161
   PubMedGoogle Scholar
• Fillingim RB, Kaplan L, Staud R, et al. The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans. J Pain. 2005;6(3):159–167. doi:10.1016/j.jpain.2004.11.008
   PubMed Web of Science ®Google Scholar