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ORIGINAL RESEARCH

Impact of Prehospital Antibiotics on in-Hospital Mortality in Emergency Medical Service Patients with Sepsis

ORCID Icon, &
Pages 199-206 | Received 23 Mar 2023, Accepted 22 May 2023, Published online: 26 May 2023

References

  • Fernando SM, Rochwerg B, Seely AJE. Clinical implications of the third international consensus definitions for sepsis and septic shock (sepsis-3). CMAJ. 2018;190(36):E1058–E1059. doi:10.1503/cmaj.170149
  • Fleischmann C, Scherag A, Adhikari NK, et al. Assessment of global incidence and mortality of hospital-treated sepsis. Current estimates and limitations. Am J Respir Crit Care Med. 2016;193(3):259–272. doi:10.1164/rccm.201504-0781OC
  • Bureau of Medical system supervision. Inspections Report 2021. Thailand: Bureau of Medical system supervision, department of medical services, Thailand ministry of public health; 2021.
  • Evans L, Rhodes A, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47(11):1181–1247. doi:10.1007/s00134-021-06506-y
  • Walchok JG, Pirrallo RG, Furmanek D, et al. Paramedic-initiated CMS sepsis core measure bundle prior to hospital arrival: a stepwise approach. Prehosp Emerg Care. 2017;21(3):291–300. doi:10.1080/10903127.2016.1254694
  • Hunter CL, Silvestri S, Stone A, et al. Prehospital sepsis alert notification decreases time to initiation of CMS sepsis core measures. Am J Emerg Med. 2019;37(1):114–117. doi:10.1016/j.ajem.2018.09.034
  • Cudini D, Smith K, Bernard S, et al. Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients?. Emerg Med Australas. 2019;31(4):669–672.
  • Borrelli G, Koch E, Sterk E, Lovett S, Rech MA. Early recognition of sepsis through emergency medical services pre-hospital screening. Am J Emerg Med. 2019;37(8):1428–1432. doi:10.1016/j.ajem.2018.10.036
  • Moore C, Bulger J, Morgan M, et al. Prehospital recognition and antibiotics for 999 patients with sepsis: protocol for a feasibility study. Pilot Feasibility Stud. 2018;4:64. doi:10.1186/s40814-018-0258-8
  • Chippendale J, Lloyd A, Payne T, Dunmore S, Stoddart B. The feasibility of paramedics delivering antibiotic treatment pre-hospital to ‘red flag’ sepsis patients: a service evaluation. Br Paramed J. 2018;2(4):19–24. doi:10.29045/14784726.2018.03.2.4.19
  • Mixon M, Dietrich S, Floren M, et al. Time to antibiotic administration: sepsis alerts called in emergency department versus in the field via emergency medical services. Am J Emerg Med. 2021;44:291–295. doi:10.1016/j.ajem.2020.04.008
  • Peltan ID, Mitchell KH, Rudd KE, et al. Prehospital care and emergency department door-to-antibiotic time in sepsis. Ann Am Thorac Soc. 2018;15(12):1443–1450. doi:10.1513/AnnalsATS.201803-199OC
  • Alam N, Oskam E, Stassen PM, et al. Prehospital antibiotics in the ambulance for sepsis: a multicentre, open label, randomised trial. Lancet Respir Med. 2018;6(1):40–50. doi:10.1016/S2213-2600(17)30469-1
  • Martel T, Melmer MN, Leaman SM, et al. Prehospital antibiotics improve morbidity and mortality of emergency medical service patients with sepsis. HCA Healthcare J Med. 2020;1:3. doi:10.36518/2689-0216.1063
  • Jouffroy R, Gilbert B, Tourtier JP, et al. Impact of prehospital antibiotic therapy on septic shock mortality. Prehosp Emerg Care. 2021;25(3):317–324. doi:10.1080/10903127.2020.1763532
  • Nannan Panday RS, Wang S, Schermer EH, Cooksley T, Alam N, Nanayakkara PWB. Septic patients with cancer: do prehospital antibiotics improve survival? A sub-analysis of the PHANTASi trial. Neth J Med. 2020;78(1):3–9.
  • Al-Shaqsi S. Models of international Emergency Medical Service (EMS) systems. Oman Med J. 2010;25(4):320–323. doi:10.5001/omj.2010.92
  • Prehospital Sepsis Protocol [Homepage on the Internet]. Narenthorn EMS center; 2021. Available form: https://www.narenthorn.or.th. Accessed January 21, 2023.
  • Rosner B. Fundamentals of Biostatistics. 5th ed. Duxbury; 2000:792.
  • Yang Y, Yang KS, Hsann YM, Lim V, Ong BC. The effect of comorbidity and age on hospital mortality and length of stay in patients with sepsis. J Crit Care. 2010;25(3):398–405. doi:10.1016/j.jcrc.2009.09.001
  • da Silva Ramos FJ, de Freitas FGR, Machado FR. Sepsis in patients hospitalized with coronavirus disease 2019: how often and how severe? Curr Opin Crit Care. 2021;27(5):474–479. doi:10.1097/MCC.0000000000000861