88
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Impact of Clinician Subjectivity on the Assessment of Dry Eye Disease Prevalence in a UK Public Health Care Patient Population

, , , &
Pages 743-753 | Received 28 Nov 2023, Accepted 15 Feb 2024, Published online: 08 Mar 2024

References

  • Luo L, Li DQ, Pflugfelder SC. Hyperosmolarity-induced Apoptosis in Human Corneal Epithelial Cells Is Mediated by Cytochrome C and MAPK Pathways. Cornea. 2007;26(4):452–460. doi:10.1097/ICO.0b013e318030d259
  • Chen Z, Tong L, Li Z, et al. Hyperosmolarity-induced cornification of human corneal epithelial cells is regulated by JNK MAPK. Invest Ophthalmol Vis Sci. 2008;49(2):539–549. doi:10.1167/iovs.07-0569
  • Luo L, Li DQ, Corrales RM, Pflugfelder SC. Hyperosmolar saline is a proinflammatory stress on the mouse ocular surface. Eye Contact Lens. 2005;31(5):186–193. doi:10.1097/01.icl.0000162759.79740.46
  • Igarashi T, Fujimoto C, Suzuki H, et al. Short-time exposure of hyperosmolarity triggers interleukin-6 expression in corneal epithelial cells. Cornea. 2014;33(12):1342–1347. doi:10.1097/ICO.0000000000000256
  • Zibandeh N, Yıldız E, Özer B, Taş AY, Sahin A. Androgen Suppresses Hyperosmolarity-Induced Inflammatory Mediators in Human Corneal Epithelial Cells. Cornea. 2020;39(7):886–891. doi:10.1097/ICO.0000000000002291
  • Seo J, Byun WY, Alisafaei F, et al. Multiscale reverse engineering of the human ocular surface. Nat Med. 2019;25(8):1310–1318. doi:10.1038/s41591-019-0531-2
  • Hirata H, Mizerska K, Marfurt CF, Rosenblatt MI. Hyperosmolar Tears Induce Functional and Structural Alterations of Corneal Nerves: electrophysiological and Anatomical Evidence Toward Neurotoxicity. Invest Ophthalmol Vis Sci. 2015;56(13):8125–8140. doi:10.1167/iovs.15-18383
  • Parra A, Gonzalez-Gonzalez O, Gallar J, Belmonte C. Tear fluid hyperosmolality increases nerve impulse activity of cold thermoreceptor endings of the cornea. Pain. 2014;155(8):1481–1491. doi:10.1016/j.pain.2014.04.025
  • Hirata H, Rosenblatt MI. Hyperosmolar tears enhance cooling sensitivity of the corneal nerves in rats: possible neural basis for cold-induced dry eye pain. Invest Ophthalmol Vis Sci. 2014;55(9):5821–5833. doi:10.1167/iovs.14-14642
  • Bron AJ, de Paiva CS, Chauhan SK, et al. TFOS DEWS II pathophysiology report. Ocul Surf. 2017;15(3):438–510. doi:10.1016/j.jtos.2017.05.011
  • Potvin R, Makari S, Rapuano CJ. Tear film osmolarity and dry eye disease: a review of the literature. Clin Ophthalmol. 2015;9:2039–2047. doi:10.2147/OPTH.S95242
  • Versura P, Profazio V, Campos EC. Performance of tear osmolarity compared to previous diagnostic tests for dry eye diseases. Curr Eye Res. 2010;35(7):553–564. doi:10.3109/02713683.2010.484557
  • Lemp MA, Bron AJ, Baudouin C, et al. Tear osmolarity in the diagnosis and management of dry eye disease. Am J Ophthalmol. 2011;151(5):792–798.e1. doi:10.1016/j.ajo.2010.10.032
  • Jacobi C, Jacobi A, Kruse FE, Cursiefen C. Tear film osmolarity measurements in dry eye disease using electrical impedance technology. Cornea. 2011;30(12):1289–1292. doi:10.1097/ICO.0b013e31821de383
  • Pepose JS, Qazi MA, Devries DK. Longitudinal changes in dry eye symptoms and signs following lifitegrast therapy and relationship to tear osmolarity. Clin Ophthalmol. 2019;13:571–579. doi:10.2147/OPTH.S196593
  • Montani G. Intrasubject tear osmolarity changes with two different types of eyedrops. Optom Vis Sci. 2013;90(4):372–377. doi:10.1097/OPX.0b013e318288bdbe
  • Benelli U, Nardi M, Posarelli C, Albert TG. Tear osmolarity measurement using the TearLab Osmolarity System in the assessment of dry eye treatment effectiveness. Cont Lens Anterior Eye. 2010;33(2):61–67. doi:10.1016/j.clae.2010.01.003
  • Janulevičienė I, Derkač I, Grybauskiene L, Paulauskaitė R, Gromnickaite R, Kuzmienė L. Effects of preservative-free tafluprost on tear film osmolarity, tolerability, and intraocular pressure in previously treated patients with open-angle glaucoma. Clin Ophthalmol. 2012;6:103–109. doi:10.2147/OPTH.S28104
  • Epitropoulos AT, Donnenfeld ED, Shah ZA, et al. Effect of Oral Re-esterified Omega-3 Nutritional Supplementation on Dry Eyes. Cornea. 2016;35(9):1185–1191. doi:10.1097/ICO.0000000000000940
  • Sullivan BD, Crews LA, Sönmez B, et al. Clinical utility of objective tests for dry eye disease: variability over time and implications for clinical trials and disease management. Cornea. 2012;31(9):1000–1008. doi:10.1097/ICO.0b013e318242fd60
  • Sullivan BD, Whitmer D, Nichols KK, et al. An objective approach to dry eye disease severity. Invest Ophthalmol Vis Sci. 2010;51(12):6125–6130. doi:10.1167/iovs.10-5390
  • Gagliano C, Visalli E, Toro MD, et al. Dry Eye in Systemic Sclerosis Patients: novel Methods to Monitor Disease Activity. Diagnostics. 2020;10(6):404. doi:10.3390/diagnostics10060404
  • Kim M, Kim HS, Na KS. Correlation between Tear Osmolarity and Other Ocular Surface Parameters in Primary Sjögren’s Syndrome. Korean J Ophthalmol. 2017;31(1):25–31. doi:10.3341/kjo.2017.31.1.25
  • Epitropoulos AT, Matossian C, Berdy GJ, Malhotra RP, Potvin R. Effect of tear osmolarity on repeatability of keratometry for cataract surgery planning. J Cataract Refract Surg. 2015;41(8):1672–1677. doi:10.1016/j.jcrs.2015.01.016
  • Kursite A, Laganovska G. Effect of tear osmolarity on postoperative refractive error after cataract surgery. J.ophthalmol. 2023;1(2):11–15.
  • Fuerst N, Langelier N, Massaro-Giordano M, et al. Tear osmolarity and dry eye symptoms in diabetics. Clin Ophthalmol. 2014;8:507–515. doi:10.2147/OPTH.S51514
  • Attas-Fox L, Zhang AY, Fox BD, Arthurs BP. Evaluation of tearing in oculoplastics assisted by tear osmolarity measurement. Orbit. 2014;33(5):331–335. doi:10.3109/01676830.2014.882362
  • Nieto-Bona A, Nombela-Palomo M, Felipe-Márquez G, Teus MA. Tear Film Osmolarity in Response to Long-Term Orthokeratology Treatment. Eye Contact Lens. 2018;44(2):85–90. doi:10.1097/ICL.0000000000000347
  • Kacerovská J, Kacerovský M, Hlaváčková M, Studený P. Change of tear osmolarity after refractive surgery. Cesk Slov Oftalmol. 2018;74(1):18–22.
  • Messmer EM, Bulgen M, Kampik A. Hyperosmolarity of the tear film in dry eye syndrome. Dev Ophthalmol. 2010;45:129–138. doi:10.1159/000315026
  • Gonzales JA, Shiboski SC, Bunya VY, et al. Ocular Clinical Signs and Diagnostic Tests Most Compatible With Keratoconjunctivitis Sicca: a Latent Class Approach. Cornea. 2020;39(8):1013–1016. doi:10.1097/ICO.0000000000002311
  • Tashbayev B, Utheim TP, Utheim ØA, et al. Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease. Sci Rep. 2020;10(1):5542. doi:10.1038/s41598-020-62583-x
  • Karakus S, Akpek EK, Agrawal D, Massof RW. Validation of an Objective Measure of Dry Eye Severity. Transl Vis Sci Technol. 2018;7(5):26. doi:10.1167/tvst.7.5.26
  • Amparo F, Jin Y, Hamrah P, Schaumberg DA, Dana R. What is the value of incorporating tear osmolarity measurement in assessing patient response to therapy in dry eye disease? Am J Ophthalmol. 2014;157(1):69–77.e2. doi:10.1016/j.ajo.2013.07.019
  • Szalai E, Berta A, Szekanecz Z, Szûcs G, Módis L. Evaluation of tear osmolarity in non-Sjögren and Sjögren syndrome dry eye patients with the TearLab system. Cornea. 2012;31(8):867–871. doi:10.1097/ICO.0b013e3182532047
  • Caffery B, Chalmers RL, Marsden H, et al. Correlation of tear osmolarity and dry eye symptoms in convention attendees. Optom Vis Sci. 2014;91(2):142–149. doi:10.1097/OPX.0000000000000130
  • Greiner JV, Ying GS, Pistilli M, Maguire MG, Asbell PA; Dry Eye Assessment and Management (DREAM) Study Research Group. Association of Tear Osmolarity With Signs and Symptoms of Dry Eye Disease in the Dry Eye Assessment and Management (DREAM) Study. Invest Ophthalmol Vis Sci. 2023;64(1):5. doi:10.1167/iovs.64.1.5
  • Khanal S, Millar TJ. Barriers to clinical uptake of tear osmolarity measurements. Br J Ophthalmol. 2012;96(3):341–344. doi:10.1136/bjo.2011.202754
  • Bunya VY, Fuerst NM, Pistilli M, et al. Variability of Tear Osmolarity in Patients With Dry Eye. JAMA Ophthalmol. 2015;133(6):662–667. doi:10.1001/jamaophthalmol.2015.0429
  • Szczesna-Iskander DH. Measurement variability of the TearLab Osmolarity System. Cont Lens Anterior Eye. 2016;39(5):353–358. doi:10.1016/j.clae.2016.06.006
  • Baenninger PB, Voegeli S, Bachmann LM, et al. Variability of Tear Osmolarity Measurements With a Point-of-Care System in Healthy Subjects-Systematic Review. Cornea. 2018;37(7):938–945. doi:10.1097/ICO.0000000000001562
  • Wolffsohn JS, Arita R, Chalmers R, et al. TFOS DEWS II Diagnostic Methodology report. Ocul Surf. 2017;15(3):539–574. doi:10.1016/j.jtos.2017.05.001
  • Bron AJ, Argüeso P, Irkec M, Bright FV. Clinical staining of the ocular surface: mechanisms and interpretations. Prog Retin Eye Res. 2015;44:36–61. doi:10.1016/j.preteyeres.2014.10.001
  • Kourukmas R, Roth M, Geerling G. Automated vs. human evaluation of corneal staining. Graefes Arch Clin Exp Ophthalmol. 2022;260(8):2605–2612. doi:10.1007/s00417-022-05574-0
  • Lemp MA, Crews LA, Bron AJ, Foulks GN, Sullivan BD. Distribution of aqueous-deficient and evaporative dry eye in a clinic-based patient cohort: a retrospective study. Cornea. 2012;31(5):472–478. doi:10.1097/ICO.0b013e318225415a
  • Tsubota K. Short Tear Film Breakup Time-Type Dry Eye. Invest Ophthalmol Vis Sci. 2018;59(14):DES64–DES70. doi:10.1167/iovs.17-23746
  • Deinema LA, Vingrys AJ, Chinnery HR, Downie LE. Optical Coherence Tomography Reveals Changes to Corneal Reflectivity and Thickness in Individuals with Tear Hyperosmolarity. Transl Vis Sci Technol. 2017;6(3):6. doi:10.1167/tvst.6.3.6
  • Nichols KK, Nichols JJ, Mitchell GL. The lack of association between signs and symptoms in patients with dry eye disease. Cornea. 2004;23(8):762–770. doi:10.1097/01.ico.0000133997.07144.9e
  • Sullivan BD, Crews LA, Messmer EM, et al. Correlations between commonly used objective signs and symptoms for the diagnosis of dry eye disease: clinical implications. Acta Ophthalmol. 2014;92(2):161–166. doi:10.1111/aos.12012