References
- Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics, 2021. CA Cancer J Clin. 2021;71(1):7–33. doi:10.3322/caac.21654
- Wu F, Wang L, Zhou C. Lung cancer in China: current and prospect. Curr Opin Oncol. 2021;33(1):40–46. doi:10.1097/CCO.0000000000000703
- Hirsch FR, Scagliotti GV, Mulshine JL, et al. Lung cancer: current therapies and new targeted treatments. Lancet. 2017;389(10066):299–311. doi:10.1016/S0140-6736(16)30958-8
- Akhtar-Danseh GG, Akhtar-Danesh N, Finley C. Uptake and survival effects of minimally invasive surgery for lung cancer: a population-based study. Eur J Surg Oncol. 2021;47(7):1791–1796. doi:10.1016/j.ejso.2021.01.002
- D’Souza CA, Heitman J. Dismantling the Cryptococcus coat. Trends Microbiol. 2001;9(3):112–113. doi:10.1016/S0966-842X(00)01945-4
- Man SM, Kanneganti TD. Converging roles of caspases in inflammasome activation, cell death and innate immunity. Nat Rev Immunol. 2016;16(1):7–21. doi:10.1038/nri.2015.7
- Wei X, Xie F, Zhou X, et al. Role of pyroptosis in inflammation and cancer. Cell Mol Immunol. 2022;19(9):971–992. doi:10.1038/s41423-022-00905-x
- Yu P, Zhang X, Liu N, et al. Pyroptosis: mechanisms and diseases. Signal Transduct Target Ther. 2021;6(1):128. doi:10.1038/s41392-021-00507-5
- Pandey A, Shen C, Feng S, et al. Cell biology of inflammasome activation. Trends Cell Biol. 2021;31(11):924–939. doi:10.1016/j.tcb.2021.06.010
- Brydges SD, Broderick L, McGeough MD, et al. Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies. J Clin Invest. 2013;123(11):4695–4705. doi:10.1172/JCI71543
- Sharma BR, Kanneganti TD. NLRP3 inflammasome in cancer and metabolic diseases. Nat Immunol. 2021;22(5):550–559. doi:10.1038/s41590-021-00886-5
- Hu Z, Yan C, Liu P, et al. Crystal structure of NLRC4 reveals its autoinhibition mechanism. Science. 2013;341(6142):172–175. doi:10.1126/science.1236381
- Li T, Liu H, Dong C, et al. Prognostic implications of pyroptosis-related gene signatures in lung squamous cell carcinoma. Front Pharmacol. 2022;13:806995. doi:10.3389/fphar.2022.806995
- Xu G, Huang R, Xia W, et al. Associations between inflammasome-related gene NLRP3 Polymorphisms (rs10754558 and rs35829419) and risk of bladder cancer in a Chinese population. J Clin Lab Anal. 2021;35(11):e23973. doi:10.1002/jcla.23973
- Zhong J, Liu L, Lu Y, et al. NLRP3, NLRC4 and NLRC5 gene polymorphisms associate with susceptibility of pulmonary aspergillosis in non-neutropenic patients. J Clin Med. 2022;11(7):1870. doi:10.3390/jcm11071870
- Gomes Torres A, Leite N, Tureck LV, et al. Association between Toll-like receptors (TLR) and NOD-like receptor (NLR) polymorphisms and lipid and glucose metabolism. Gene. 2019;685:211–221. doi:10.1016/j.gene.2018.11.065
- Ravimohan S, Maenetje P, Auld SC, et al. A common NLRC4 gene variant associates with inflammation and pulmonary function in human immunodeficiency virus and tuberculosis. Clin Infect Dis. 2020;71(4):924–932. doi:10.1093/cid/ciz898
- Aghajanova L, Mahadevan S, Altmae S, et al. No evidence for mutations in NLRP7, NLRP2 or KHDC3L in women with unexplained recurrent pregnancy loss or infertility. Hum Reprod. 2015;30(1):232–238. doi:10.1093/humrep/deu296
- Gabriel S, Ziaugra L, Tabbaa D. SNP genotyping using the Sequenom MassARRAY iPLEX platform. Curr Protoc Hum Genet. 2009;60(1). doi:10.1002/0471142905.hg0212s60
- Karki R, Man SM, Kanneganti TD. Inflammasomes and Cancer. Cancer Immunol Res. 2017;5(2):94–99. doi:10.1158/2326-6066.CIR-16-0269
- Mishra SR, Mahapatra KK, Behera BP, et al. Inflammasomes in cancer: effect of epigenetic and autophagic modulations. Semin Cancer Biol. 2022;83:399–412. doi:10.1016/j.semcancer.2020.09.013
- Kelley N, Jeltema D, Duan Y, et al. The NLRP3 inflammasome: an overview of mechanisms of activation and regulation. Int J Mol Sci. 2019;20(13):3328. doi:10.3390/ijms20133328
- Xia X, Wang X, Cheng Z, et al. The role of pyroptosis in cancer: pro-cancer or pro-“host”? Cell Death Dis. 2019;10(9):650. doi:10.1038/s41419-019-1883-8
- Winter RN, Rhee JG, Kyprianou N. Caspase-1 enhances the apoptotic response of prostate cancer cells to ionizing radiation. Anticancer Res. 2004;24(3a):1377–1386.
- Wang Q, Wang Y, Ding J, et al. A bioorthogonal system reveals antitumour immune function of pyroptosis. Nature. 2020;579(7799):421–426. doi:10.1038/s41586-020-2079-1
- Zaki MH, Vogel P, Body-Malapel M, et al. IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. J Immunol. 2010;185(8):4912–4920. doi:10.4049/jimmunol.1002046
- Yuan R, Zhao W, Wang -Q-Q, et al. Cucurbitacin B inhibits non-small cell lung cancer in vivo and in vitro by triggering TLR4/NLRP3/GSDMD-dependent pyroptosis. Pharmacol Res. 2021;170:105748. doi:10.1016/j.phrs.2021.105748
- Liang Q, Cai W, Zhao Y, et al. Lycorine ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3 inflammasome activation and pyroptosis. Pharmacol Res. 2020;158:104884. doi:10.1016/j.phrs.2020.104884
- Wen J, Xuan B, Liu Y, et al. Updating the NLRC4 inflammasome: from bacterial infections to autoimmunity and cancer. Front Immunol. 2021;12:702527. doi:10.3389/fimmu.2021.702527
- Hu B, Elinav E, Huber S, et al. Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. Proc Natl Acad Sci U S A. 2010;107(50):21635–21640. doi:10.1073/pnas.1016814108
- Janowski AM, Colegio OR, Hornick EE, et al. NLRC4 suppresses melanoma tumor progression independently of inflammasome activation. J Clin Invest. 2016;126(10):3917–3928. doi:10.1172/JCI86953
- Kolb R, Phan L, Borcherding N, et al. Obesity-associated NLRC4 inflammasome activation drives breast cancer progression. Nat Commun. 2016;7(1):13007. doi:10.1038/ncomms13007
- Ohashi K, Wang Z, Yang YM, et al. NOD-like receptor C4 inflammasome regulates the growth of colon cancer liver metastasis in NAFLD. Hepatology. 2019;70(5):1582–1599.
- Kinoshita T, Wang Y, Hasegawa M, Imamura R, Suda T. PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. J Biol Chem. 2005;280(23):21720–21725. doi:10.1074/jbc.M410057200
- Messaed C, Akoury E, Djuric U, et al. NLRP7, a nucleotide oligomerization domain-like receptor protein, is required for normal cytokine secretion and co-localizes with Golgi and the microtubule-organizing center. J Biol Chem. 2011;286(50):43313–43323. doi:10.1074/jbc.M111.306191
- Khare S, Dorfleutner A, Bryan N, et al. An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages. Immunity. 2012;36(3):464–476. doi:10.1016/j.immuni.2012.02.001
- Zhou Y, Shah SZA, Yang L, et al. Virulent mycobacterium bovis Beijing strain activates the NLRP7 inflammasome in THP-1 macrophages. PLoS One. 2016;11(4):e0152853. doi:10.1371/journal.pone.0152853
- Carriere J, Dorfleutner A, Stehlik C. NLRP7: from inflammasome regulation to human disease. Immunology. 2021;163(4):363–376. doi:10.1111/imm.13372
- Yin J, Wang C, Vogel U, et al. Common variants of pro-inflammatory gene IL1B and interactions with PPP1R13L and POLR1G in relation to lung cancer among Northeast Chinese. Sci Rep. 2023;13(1):7352. doi:10.1038/s41598-023-34069-z
- Wang C, Dai J, Qin N, et al. Analyses of rare predisposing variants of lung cancer in 6004 whole genomes in Chinese. Cancer Cell. 2022;40(10):1223–1239.e6. doi:10.1016/j.ccell.2022.08.013
- Ji Y, Yang Y, Yin Z. Polymorphisms in lncRNA CCAT1 on the susceptibility of lung cancer in a Chinese northeast population: a case-control study. Cancer Med. 2023;12(1):500–512. doi:10.1002/cam4.4902
- Yu Y, Mao L, Cheng Z, et al. A novel regQTL-SNP and the risk of lung cancer: a multi-dimensional study. Arch Toxicol. 2021;95(12):3815–3827. doi:10.1007/s00204-021-03170-5