4
Views
10
CrossRef citations to date
0
Altmetric
Original Article

Role of Histamine and Calcitonin Gene-related Peptide in the Hyperemic Response to Hypertonic Saline and H+ Back-Diffusion in the Gastric Mucosa of Cats

, , , , &
Pages 300-310 | Received 25 Apr 1994, Accepted 23 Jun 1994, Published online: 08 Jul 2009

References

  • Grønbech J E, Matre K, Stangeland L, Svanes K, Varhaug J E. Gastric mucosal repair in the cat: role of the hyperemic response to mucosal damage. Gastroenterology 1988; 95: 311–20
  • Svanes K, Gislason H, Guttu K, Herfjord J K, Fevang J, Grønbech J E. Role of blood flow in adaptive protection of the cat gastric mucosa. Gastroenterology 1991; 100: 1249–58
  • Gislason H, Herfjord J K, Guttu K, Grong K, Grønbech J E, Ulvik R, et al. Adaptive protection related to clearance of ethanol in gastric mucosa of cats. Scand J Gastroenterol 1993; 28: 361–8
  • Whittle B JR. Mechanisms underlying gastric mucosal damage induced by indomethacin and bile salts, and the actions of prostaglandins. Br J Pharmacol 1977; 60: 455–60
  • Holzer P, Livingston E H, Guth P H. Sensory neurons signal for increase in rat gastric mucosal blood flow in the face of pending acid injury. Gastroenterology 1991; 101: 416–23
  • Holzer P, Lippe I T. Gastric mucosal hyperemia due to acid backdiffusion depends on splanchnic nerve activity. Am J Physiol 1992; 262: G505–9
  • Li D S, Raybould H E, Quintero E, Guth P H. Calcitonin gene-related peptide mediates the gastric hyperemic response to acid back-diffusion. Gastroenterology 1992; 102: 1124–8
  • Whittle B JR, Lopez-Belmonte J, Moncada S. Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat. Br J Pharmacol 1990; 99: 607–11
  • Bruggeman T M, Wood J G, Davenport H W. Local control of blood flow in the dog's stomach: vasodilatation caused by acid back-diffusion following topical application of salicylic acid. Gastroenterology 1979; 77: 736–44
  • Stead R H, Dixon M F, Bramwell N H, Riddell R H, Bienenstock J. Mast cells are closely apposed to nerves in the human gastrointestinal mucosa. Gastroenterology 1989; 97: 575–85
  • Stead R H, Tomioka M, Riddell R H, Bienenstock J. Substance P and/or calcitonin gene-related peptide are present in subepithelial enteric nerves apposed to intestinal mucosal mast cells. Inflammatory bowel disease: current status and future approach, R P MacDermott. Elsevier, Amsterdam 1988; 43–8
  • Bienenstock J, Macqueen G, Sestini P, Marshall J S, Stead R H, Perdue M H. Mast cell/nerve interaction in vitro and in vivo. Am Rev Respir Dis 1991; 143: S55–8
  • Holzer P, Pabst M A, Lippe I Th, Peskar B M, Peskar B A, Livingston E H, et al. Afferent nerve-mediated protection against deep mucosal damage in the rat stomach. Gastroenterology 1990; 98: 838–48
  • Holzer P, Peskar B M, Peskar B A, Amann R. Release of calcitonin gene-related peptide induced by capsaicin in the vas-cularly perfused rat stomach. Neurosci Lett 1990; 108: 195–200
  • Chen R YZ, Li D S, Guth P H. Role of calcitonin gene-related peptide in capsaicin-induced gastric submucosal arteriolar dilation. Am J Physiol 1992; 262: H1350–5
  • Shanahan F, Denburg J A, Fox J, Bienenstock J, Befus D. Mast cell heterogeneity: effects of neuroenteric peptides on histamine relese. J Immunol 1985; 135: 1331–7
  • Piotrowski W, Foreman J C. Some effects of calcitonin gene-related peptide in human skin and on histamine release. Br J Dermatol 1986; 114: 37–46
  • Wallace J L, McKnight G W, Befus A D. Capsaicin-induced hyperemia in the stomach: possible contribution of mast cells. Am J Physiol 1992; 263: G209–14
  • Endoh K, Kao J, Domek M J, Leung F W. Mechanism of gastric hyperemia induced by intragastric hypertonic saline in rats. Gastroenterology 1993; 104: 114–21
  • Håkanson R, Böttcher G, Ekblad E, Panula P, Simonsson M, Dohlsten M, et al. Histamine in endocrine cells in the stomach: a survey of several species using a panel of histamine antibodies. Histochemistry 1986; 86: 5–17
  • Sundler F, Ekblad E, Håkanson R. Occurrence and distribution of SP- and CGRP-containing nerve fibers in gastric mucosa: Species differences. Sensory nerve and neuropeptides in gastroenterology: from basic science to clinical perspectives, M Costa, C Surrenti, S Gorini, C A Maggi, A Meli. Plenum Press, New York 1991; 29–37
  • Heyman M A, Payne B D, Hoffman J IE, Rudolph A M. Blood flow measurements with radionuclide-labelled particles. Prog Cardiovasc Dis 1977; 20: 619–25
  • Schifter S. Circulating concentrations of calcitonin gene-related peptide (CGRP) in normal man determined with a new, highly sensitive radioimmunoassay. Peptides 1991; 12: 365–9
  • Morel A M, Delaage M A. Immunoanalysis of histamine through a novel chemical derivatization. J Allergy Clin Immunol 1988; 82: 646–54
  • Waldum H L, Sandvik A K, Brenna E, Søgnen B S. Radioimmunoassay of histamine. Scand J Gastroenterol 1991; 26(Suppl 180)32–39
  • Richards D M, Brogden R N, Heel R C, Speight T M, Avery G S. Astemizole. A review of its pharmacodynamic properties and therapeutic efficacy. Drugs 1984; 28: 38–61
  • Brittain R T, Jack D, Reeves J J, Stables R. Pharmacological basis for the induction of gastric carcinoid tumours in the rat by loxtidine, an unsurmountable histamine H2-receptor blocking drug. Br J Pharmacol 1985; 85: 843–7
  • Donoso M V, Fournier A, St-Pierre S, Huidobro-Toro J P. Pharmacological characterization of CGRP1 receptor subtype in the vascular system of the rat: studies with hCGRP fragments analogs. Peptides 1990; 11: 885–9
  • Main I HM, Whittle B JR. A study of the vascular and acid-secretory responses of the rat gastric mucosa to histamine. J Physiol 1976; 257: 407–18
  • Guth P H, Smith E, Moler T. H1 and H2 histamine receptors in rat gastric submucosal arterioles. Microvasc Res 1980; 19: 320–8
  • Gerkens J F, Flexner C, Oates J A, Shand D G. Prostaglandin and histamine involvement in the gastric vasodilator action of pentagastrin. J Pharmacol Exp Ther 1977; 201: 421–6
  • Gerber J G, Payne A. Endogenous adenosine modulates gastric acid secretion to histamine in canine parietal cells. J Pharmacol Exp Ther 1987; 244: 190–4
  • Gerber J G, Guth P H. Role of adenosine in the gastric blood flow response to pentagastrin in the rat. J Pharmacol Exp Ther 1989; 251: 550–6
  • Guttu K, Svanes K, Grønbech J E. Effect of systemic alkalinization or acidification on gastric luminal bicarbonate release, mucosal blood flow, and mucosal restitution after damage in cat. Gastroenterology 1993; 104: A92
  • Kiviluoto T, Voipio J, Kivilaakso E. Subepithelial tissue pH of rat gastric mucosa exposed to luminal acid, barrier breaking agents, and hemorrhagic shock. Gastroenterology 1988; 94: 695–702
  • Johnson L R, Overholt B F. Release of histamine into gastric venous blood following injury by acetic or salicylic acid. Gastroenterology 1967; 52: 505–9
  • Walls A F, Brain S D, Desai A, Jose P J, Hawkings E, Church M K, et al. Human mast cell tryptase attenuates the vasodilator activity of calcitonin gene-related peptide. Biochem Pharmacol 1992; 43: 1243–8
  • Lacy E R, Ito S. Microscopic analysis of ethanol damage to rat gastric mucosa after treatment with a prostaglandin. Gastroenterology 1982; 83: 619–25

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.