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Original Article

The Effect of Dydrogesterone on Premenstrual Symptoms: A Double-blind, Randomized, Placebo-controlled Study in General Practice

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Pages 179-183 | Received 01 Jan 1987, Accepted 01 Feb 1988, Published online: 12 Jul 2009

References

  • Pedersen C, Pedersen P A., Kamper-Jørgensen F. Some premenstrual symptoms. Ugeskr Læger 1981; 143: 1105–8
  • Dalton K. The premenstrual syndrome and progesterone therapy. W. Heinemann Medical Books Ltd., London 1977
  • Munday M. Hormone levels in severe premenstrual tension syndrome. Curr Med Res Opin 1977; 4(Suppl 4)16–22
  • Bäckström T, Carstensen H. Estrogen and progesterone in plasma in relation to premenstrual tension. J Steroid Biochem 1974; 5: 257–60
  • O'Brian P MS, Selby C, Symonds E M. Progesterone, fluid, and electrolytes in premenstrual syndrome. Br Med J 1980; 280: 1161–3
  • Williams J GC, Martin A J., Hulkenberg-Tromp T EML. PMS in European countries. Part 2. A double-blind placebo controlled study of dydrogesterone. Br J Sex Med 1983; 10: 8–18
  • Kerr G D., Day J B., Munday M R., Brush M G., Watson M, Taylor R W. Dydrogesterone in the treatment of the premenstrual syndrome. Practitioner 1980; 224: 852–5
  • Day J B. Clinical trials in the premenstrual syndrome. Curr Med Res Opin 1979; 6(Suppl 5)40–5
  • Taylor R W. The treatment of premenstrual tension with dydrogesterone (‘Duphaston’). Curr Med Res Opin 1977; 4(Suppl 4)35–40
  • Dennerstein L, Spencer-Gardner C, Gottes G, Brown J B., Smith M A., Burrows G D. Progesterone and the premenstrual syndrome; A double blind crossover trial. Br Med J 1985; 290: 1617–21
  • Freiman J A., Chalmers T C., Smith H, Kuebler R R. The importance of Beta, the Type II Error and sample size in the design and interpretation of the randomized control trial. N Engl J Med 1978; 299: 690–4

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