References
- Analitis A, Katsouyanni K, Dimakopoulou K, et al. (2006). Short-term effects of ambient particles on cardiovascular and respiratory mortality. Epidemiology 17:230–3
- Ananthakrishnan AN, McGinley EL, Binion DG, Saeian K. (2011). Ambient air pollution correlates with hospitalizations for inflammatory bowel disease: an ecologic analysis. Inflammatory Bowel Dis 17:1138–45
- Bai N, Kido T, Suzuki H, et al. (2011). Changes in atherosclerotic plaques induced by inhalation of diesel exhaust. Atherosclerosis 216:299–306
- Bauer RN, Diaz-Sanchez D, Jaspers I. (2012). Effects of air pollutants on innate immunity: the role of toll-like receptors and nucleotide-binding oligomerization domain-like receptors. J Allergy Clin Immunol 129:14–24; quiz 25-16
- Beamish LA, Osornio-Vargas AR, Wine E. (2011). Air pollution: an environmental factor contributing to intestinal disease. J Crohns Colitis 5:279–86
- Bezemer GF, Sagar S, van Bergenhenegouwen J, et al. (2012). Dual role of toll-like receptors in asthma and chronic obstructive pulmonary disease. Pharmacol Rev 64:337–58
- Brook RD, Rajagopalan S, Pope CA, III et al. (2010). Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American heart association. Circulation 121:2331–78
- Campen MJ. (2012). Vascular endothelium as a target of diesel particulate matter-associated toxicants. Arch Toxicol 86:517–18
- Campen MJ, Lund AK, Knuckles TL, et al. (2010). Inhaled diesel emissions alter atherosclerotic plaque composition in apoe(−/−) mice. Toxicol Appl Pharmacol 242:310–17
- Campen M, Robertson S, Lund A, et al. (2014). Engine exhaust particulate and gas phase contributions to vascular toxicity. Inhal Toxicol 26:353–60
- Channell MM, Paffett ML, Devlin RB, et al. (2012). Circulating factors induce coronary endothelial cell activation following exposure to inhaled diesel exhaust and nitrogen dioxide in humans: evidence from a novel translational in vitro model. Toxicol Sci 127:179–86
- Cherng TW, Paffett ML, Jackson-Weaver O, et al. (2011). Mechanisms of diesel-induced endothelial nitric oxide synthase dysfunction in coronary arterioles. Environ Health Perspect 119:98–103
- Dockery DW, Pope CA, III Xu X, et al. (1993). An association between air pollution and mortality in six U.S. cities. N Engl J Med 329:1753–9
- Eisenhart C. (1947). The assumptions underlying the analysis of variance. Biometrics 3:1–21
- Farhat SC, Silva CA, Orione MA, et al. (2011). Air pollution in autoimmune rheumatic diseases: a review. Autoimmun Rev 11:14–21
- Hubbard HF, Sobus JR, Pleil JD, et al. (2009). Application of novel method to measure endogenous vocs in exhaled breath condensate before and after exposure to diesel exhaust. J chromatogr B Anal Technol Biomed Life Sci 877:3652–8
- Kampfrath T, Maiseyeu A, Ying Z, et al. (2011). Chronic fine particulate matter exposure induces systemic vascular dysfunction via nadph oxidase and tlr4 pathways. Circ Res 108:716–26
- Kaplan G. (2011). Air pollution and the inflammatory bowel diseases. Inflamm Bowel Dis 17:1146–8
- Kitchen RR, Sabine VS, Sims AH, et al. (2010). Correcting for intra-experiment variation in illumina beadchip data is necessary to generate robust gene-expression profiles. BMC Genomics 11:134
- Knuckles TL, Buntz JG, Paffett M, et al. (2011). Formation of vascular s-nitrosothiols and plasma nitrates/nitrites following inhalation of diesel emissions. J Toxicol Environ Health A 74:828–37
- Knuckles TL, Lund AK, Lucas SN, Campen MJ. (2008). Diesel exhaust exposure enhances venoconstriction via uncoupling of enos. Toxicol Appl Pharmacol 230:346–51
- Konigshoff M, Kneidinger N, Eickelberg O. (2009). Tgf-beta signaling in copd: deciphering genetic and cellular susceptibilities for future therapeutic regimen. Swiss Med Wkly 139:554–63
- Langrish JP, Bosson J, Unosson J, et al. (2012). Cardiovascular effects of particulate air pollution exposure: time course and underlying mechanisms. J Intern Med 272:224–39
- Langrish JP, Unosson J, Bosson J, et al. (2013). Altered nitric oxide bioavailability contributes to diesel exhaust inhalation-induced cardiovascular dysfunction in man. J Am Heart Assoc 2:e004309
- Le Tertre A, Medina S, Samoli E, et al. (2002). Short-term effects of particulate air pollution on cardiovascular diseases in eight european cities. J Epidemiol Commun Health 56:773–9
- Lim H, Kim YU, Sun H, et al. (2014). Proatherogenic conditions promote autoimmune t helper 17 cell responses in vivo. Immunity 40:153–65
- Lucking AJ, Lundback M, Barath SL, et al. (2011). Particle traps prevent adverse vascular and prothrombotic effects of diesel engine exhaust inhalation in men. Circulation 123:1721–8
- Lund AK, Lucero J, Harman M, et al. (2011). The oxidized low-density lipoprotein receptor mediates vascular effects of inhaled vehicle emissions. Am J Respir Crit Care Med 184:82–91
- Lund AK, Lucero J, Lucas S, et al. (2009). Vehicular emissions induce vascular mmp-9 expression and activity associated with endothelin-1-mediated pathways. Arterioscler Thromb Vasc Biol 29:511–17
- Madden MC, Stevens T, Case M, et al. (2014). Diesel exhaust modulates ozone-induced lung function decrements in healthy human volunteers. Part Fibre Toxicol 11:37
- McDonald JD, Campen MJ, Harrod KS, et al. (2011). Engine-operating load influences diesel exhaust composition and cardiopulmonary and immune responses. Environ Health Perspect 119:1136–41
- Mi H, Muruganujan A, Thomas PD. (2013). Panther in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees. Nucleic Acids Res 41:D377–86
- Mi H, Thomas P. (2009). Panther pathway: an ontology-based pathway database coupled with data analysis tools. Methods Mol Biol 563:123–40
- Miller MR, McLean SG, Duffin R, et al. (2013). Diesel exhaust particulate increases the size and complexity of lesions in atherosclerotic mice. Part Fibre Toxicol 10:61
- Mills NL, Törnqvist H, Gonzalez MC, et al. (2007). Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease. N Eng J Med 357:1075–82
- Mills NL, Tornqvist H, Robinson SD, et al. (2005). Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis. Circulation 112:3930–6
- Nawrot TS, Perez L, Kunzli N, et al. (2011). Public health importance of triggers of myocardial infarction: a comparative risk assessment. Lancet 377:732–40
- Norata GD, Grigore L, Raselli S, et al. (2006). Triglyceride-rich lipoproteins from hypertriglyceridemic subjects induce a pro-inflammatory response in the endothelium: molecular mechanisms and gene expression studies. J Mol Cell Cardiol 40:484–94
- Norata GD, Pirillo A, Callegari E, et al. (2003). Gene expression and intracellular pathways involved in endothelial dysfunction induced by VLDL and oxidised VLDL. Cardiovasc Res 59:169–80
- Omori T, Fujimoto G, Yoshimura I, et al. (2003). Effects of particulate matter on daily mortality in 13 Japanese cities. J Epidemiol 13:314–22
- Ostro B, Broadwin R, Green S, et al. (2006). Fine particulate air pollution and mortality in nine california counties: results from calfine. Environ Health Perspect 114:29–33
- Peters A, von Klot S, Heier M, et al. (2004). Exposure to traffic and the onset of myocardial infarction. N Engl J Med 351:1721–30
- Pirillo A, Norata GD, Catapano AL. (2013). Lox-1, oxldl, and atherosclerosis. Mediat Inflamm 2013:152786
- Pope CA III. (1989). Respiratory disease associated with community air pollution and a steel mill, Utah valley. Am J Public Health 79:623–8
- Rao X, Zhong J, Maiseyeu A, et al. (2014). Cd36-dependent 7-ketocholesterol accumulation in macrophages mediates progression of atherosclerosis in response to chronic air pollution exposure. Circ Res 115:770–80
- Rich DQ, Schwartz J, Mittleman MA, et al. (2005). Association of short-term ambient air pollution concentrations and ventricular arrhythmias. Am J Epidemiol 161:1123–32
- Robertson S, Colombo ES, Lucas SN, et al. (2013). Cd36 mediates endothelial dysfunction downstream of circulating factors induced by o3 exposure. Toxicol Sci 134:304–11
- Sancini G, Farina F, Battaglia C, et al. (2014). Health risk assessment for air pollutants: alterations in lung and cardiac gene expression in mice exposed to milano winter fine particulate matter (pm2.5). PLoS one 9:e109685
- Schmid R, Baum P, Ittrich C, et al. (2010). Comparison of normalization methods for illumina beadchip humanht-12 v3. BMC Genomics 11:349
- Shi W, Chen F, Cardoso WV. (2009). Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary disease. Proc Am Thorac Soc 6:558–63
- Shih TS, Lai CH, Hung HF, et al. (2008). Elemental and organic carbon exposure in highway tollbooths: a study of Taiwanese toll station workers. Sci Total Environ 402:163–70
- Sikorski K, Czerwoniec A, Bujnicki JM, et al. (2011). Stat1 as a novel therapeutical target in pro-atherogenic signal integration of ifngamma, tlr4 and il-6 in vascular disease. Cytokine Growth Factor Rev 22:211–19
- Silverstein RL, Febbraio M. (2009). Cd36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior. Sci Signal 2:re3
- Sobus JR, Pleil JD, Madden MC, et al. (2008). Identification of surrogate measures of diesel exhaust exposure in a controlled chamber study. Environ Sci Technol 42:8822–8
- Subramanian A, Tamayo P, Mootha VK, et al. (2005). Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102:15545–50
- USEPA (U.S. Environmental Protection Agency). (2002). Health assessment document for diesel engine exhaust. Washington, DC: USEPA
- Wingender E, Chen X, Fricke E, et al. (2001). The transfac system on gene expression regulation. Nucleic Acids Res 29:281–3
- Wingender E, Chen X, Hehl R, et al. (2000). Transfac: an integrated system for gene expression regulation. Nucleic Acids Res 28:316–19
- Zanobetti A, Schwartz J. (2009). The effect of fine and coarse particulate air pollution on mortality: a national analysis. Environ Health Perspect 117:898–903
- Zhang X, Duan H, Gao F, et al. (2015). Increased micronucleus, nucleoplasmic bridge, and nuclear bud frequencies in the peripheral blood lymphocytes of diesel engine exhaust-exposed workers. Toxicol Sci 143:408–17