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Inhalation Toxicology
International Forum for Respiratory Research
Volume 4, 1992 - Issue 3
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Research Article

Early Response of the Canine Respiratory Tract Following Long-Term Exposure to a Sulfur(IV) Aerosol at Low Concentration. I. Rationale, Design, Methodology, and Summary

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Pages 159-174 | Received 30 Apr 1991, Accepted 07 Jan 1992, Published online: 27 Sep 2008

References

  • Alarie Y. C., Wakisaka I., Oka S. Sensory irritation by sulfite aerosols. Environ. Physiol. Biochem. 1973; 3: 182–184
  • Amdur M. O., Bayles J., Ugro V., Underhill D. W. Comparative irritant potency of sulfate salts. Environ. Res. 1978; 16: 1–8
  • Amdur M. O., McCarthy J. F., Gill M. W. Effects of mixing conditions on irritant potency of zinc oxide and sulfur dioxide. Am. Ind. Hyg. Assoc. J. 1983; 44: 7–13
  • Barry B. E., Miller F. J., Crapo J. D. Effects of inhalation of 0.12 and 0.25 parts per million ozone on the proximal alveolar region of juvenile and adult rats. Lab. Invest. 1985; 53: 692–704
  • Beck-Speier I., Hinze H., Holzer H. Effect of sulfite on the energy metabolism of mammalian tissues in correlation to sulfite oxidase activity. Biochim. Biophys. Acta. 1985; 841: 81–89
  • Bodem C. R., Lampton L. M., Miller D. P., Tarka E. R., Everett E. D. Endobronchial pH: Relevance to aminoglycoside activity in gram-negative bacillary pneumonia. Am. Rev. Respir. Dis. 1983; 127: 39–41
  • Chen L. C., Lam H. F., Ainsworth D., Guty J., Amdur M. O. Functional changes in the lungs of guinea pigs exposed to sodium sulfite aerosols. Toxicol. Appl. Pharmacol. 1987; 89: 1–8
  • Chen L. C., Schlesinger R. B. Response of bronchial mucociliary clearance system in rabbits to inhaled sulfite and sulfuric acid aerosols. Toxicol. Appl. Pharmacol. 1983; 71: 123–131
  • Craig N. L., Marker A. B., Novakov T. Determination of the chemical states of sulfur in ambient pollution aeorsols by X-ray photoelectron spectroscopy. Atmos. Environ. 1974; 8: 15–21
  • Cuddihy R. G., Brownstein D. G., Raabe O. G., Kanapilly J. M. Respiratory tract deposition of inhaled polydisperse aerosols in beagle dogs. J. Aerosol Sci. 1973; 435–45
  • Dasgupta P. K., DeCesare K. B., Brummer M. Determination of S(IV) in particulate matter. Atmos. Environ. 1982; 16: 917–927
  • Dasgupta P. K., Duvall T. R. Study of bisulfite and metabisulfite aerosol generation systems. Am. Ind. Hyg. Assoc. J. 1980; 41: 666–671
  • Dasgupta P. K., Raabe O. G., Duvall T. R., Tarkington B. K. Generation and characterization of sodium sulfite aerosols for applications in inhalation toxicologic research. Am. Ind. Hyg. Assoc. J. 1980; 41: 660–665
  • Eatough D. J., Hansen L. D. S(IV) chemistry in smelter produced particulate matter. Am. J. Ind Med. 1980; 1: 435–448
  • Eatough D. J., Richter B. E., Eatough N. L., Hansen L. D. Sulfur chemistry in smelter and power plant plumes in the western United States. Atmos. Environ. 1981; 15: 2241–2253
  • Ferron G. A., Dua S. K., Karg E., Kreyling W. C., Tuch T., Heyder J. Estimation of the deposition of polydisperse hygroscopic aerosol particles in the respiratory tract. J. Aerosol Sci. 1991; 22
  • Ferron G. A., Kreyling W. C., Haider B. Inhalation of salt aerosol particles. II. Growth and deposition in the human respiratory tract. J. Aerosol Sci. 1988; 19: 611–631
  • Fine J. M., Gordon T., Sheppard D. The role of pH and ionic species in sulfur dioxide-and sulfite-induced bronchoconstriction. Am. Rev. Respir. Dis. 1987; 136: 1122–1126
  • Frank N. R., Yoder R. E., Brain J. D., Yokoyama E. SO2 (35S labeled) absorption by the nose and the mouth under conditions of varying concentration and flow. Arch. Environ. Health 1969; 18: 315–322
  • Freeman G., Stephens R. J. Change in dog's lungs after long-term exposure to ozone. Arch. Environ. Health 1973; 26: 209–216
  • Carcinogenic and Mutagenic Effects of Diesel Engine Exhaust., N. Ishinishi, A. Koizumi, R. O. McClellan, W. Stöber. Elsevier, Amsterdam 1986
  • Karg E., Tuch T., Ferron G. A., Haider B., Kreyling W. G., Poter J., Ruprecht L., Heyder J. Design, operation, and performance of whole-body chambers for long-term aerosol exposure of large experimental animals. J Aerosol Sci, 23: 279–290
  • Kreyling W. G., Eder K., Erbe F., Ferron G. A., Haider B., Karg E., Ruprecht L., Schumann G. Particle deposition in the canine respiratory tract. Ann. Occup. Hyg. 1992b; 36, in press.
  • Kreyling W. G., Ferron G. A., Furst G., Heilmann P., Neuner M., Ruprecht L., Schumann G., Takenaka S., Heyder J. Early response of the canine respiratory tract following long-term exposure to a sulfur(IV) aerosol at low concentration. III. Macrophage mediated long-term particle clearance. Inhal. Toxicol. 1992a; 4: 197–233
  • Kubota K., Murakami M., Takenaka S., Kawai K., Kyono H. Effects of long-term notrogen dioxide exposure on rats lung: Morphological observations. Environ. Health Perspect. 1987; 73: 157–169
  • Last J. A., Dasgupta P. K., Etchison J. R. Inhalation toxicology of sodium sulfite aerosol in rats. Toxicol. Appl. Pharmacol. 1980; 55: 229–234
  • Maier K., Beck-Speier I., Dayal N., Heilmann P., Hinze H., Lenz A. G., Leuschel L., Matejkova E., Miaskowski U., Heyder J. Early response of the canine respiratory tract following long-term exposure to a sulfur(IV) aerosol at low concentration. II. Biochemistry and cell biology of lung lavage fluid. Inhal. roxicol. 1992; 4: 175–195
  • Mauderly J. L. Evaluation of the grade pony as a pulmonary model. Am. J. Vet. Res. 1974; 35: 1025–1031
  • Novakov T., Mueller P. K., Alcocer A. E., Vitcos J. W. Chemical composition of Pasadena aerosol by particle size and time of day. III. Chemical states of nitrogen and sulfur by photoelectron spectroscopy. J. Colloid Interface Sci. 1972; 30: 225–234
  • Petering D. H. Sulfur dioxide: a view of its reactions with biomolecules. In Biochemical. Effects of Environmental Pollutants, S. D. Lee. Ann Arbor Science., Ann Arbor, Mich 1977; 293–306
  • Rajagopalan K. V., Johnson J. L. Biological origin and metabolism of SO2. Biochemical Effects of Environmental Pollutants, S. D. Lee. Ann Arbor Science., Ann Arbor, Mich. 1977; 307–314
  • Schulz H., Eder G., Heilmann P., Ruprecht L., Schumann G., Takenaka S., Heyder J. Early response of the canine respiratory tract following long-term exposure to a sulfur(IV) aerosol at low concentration. IV. Respiratory lung function. Inhal. Toxicol. 1992; 4: 235–246
  • Shy C. M. Health consequences of human exposure. Sulfur in the Environment II, J. O. Nriagu. Wiley., New York 1978; 75–108
  • Long-Term Effects of Air Pollutants: In Canine Species., J. F. Stara, D. L. Dungworth, J. G. Orthoefer, W. S. Tyler. Report EPA-600/880–014, Environmental Protection Agency, Washington, D. C. 1980
  • Strauss W. L. Sulfhydroxyl groups and disulfide bonds: Modification of amino acid residues in studies of receptor structure and function. Membranes, Detergents, and Receptor Solubilization, J. C. Venter, L. C. Harrison, 1984; 85–97, New York Alan R. Liss.
  • Takenaka S., Furst G., Heilmann P., Heini A., Heinzmann U., Kreyling W. G., Murray A. B., Schultz H., Heyder J. Early response of the canine respiratory tract following long-term exposure to a sulfur(lV) aerosol at low concentration. V. Morphology and morphometry. Inhal. Toxicol. 1992; 4: 247–272
  • Ultman J. S. Transport and uptake of inhaled gases. Air Pollution, the Automobile, and Public Health, A. Y. Watson, R. R. Bates, D. K. Kennedy. National Academy Press., Washington, D. C. 1988; 323–366
  • Wakisaka I. Sensory irritation by sulfite aerosols on the upper respiratory tract in mice. Jpn. J, Hyg. 1976; 31: 347–352

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