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OncoImmunology
Volume 13, 2024 - Issue 1
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Original Research
Combination of T cell-redirecting strategies with a bispecific antibody blocking TGF-β and PD-L1 enhances antitumor responses
Antonio Tapia-Galisteoa Molecular Immunology Unit, Biomedical Research Institute Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain;b Cancer Immunotherapy Unit (UNICA), Hospital Universitario 12 de Octubre, Madrid, Spain;c Immuno-oncology and Immunotherapy Group, Biomedical Research Institute Hospital 12 de Octubre, Madrid, Spain;d H12O-CNIO Cancer Immunotherapy Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spainhttps://orcid.org/0000-0002-0507-8435View further author information
, Iñigo Sánchez-Rodrígueza Molecular Immunology Unit, Biomedical Research Institute Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spainhttps://orcid.org/0000-0002-6440-0922View further author information
, Javier Narbonae Department of Biochemistry and Molecular Biology, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Madrid, Spainhttps://orcid.org/0000-0002-6118-841XView further author information
, Patricia Iglesias-Hernándeza Molecular Immunology Unit, Biomedical Research Institute Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spainhttps://orcid.org/0000-0002-0815-3322View further author information
, Saray Aragón-Garcíaa Molecular Immunology Unit, Biomedical Research Institute Hospital Universitario Puerta de Hierro Majadahonda, Madrid, SpainView further author information
, Anaïs Jiménez-Reinosob Cancer Immunotherapy Unit (UNICA), Hospital Universitario 12 de Octubre, Madrid, Spain;c Immuno-oncology and Immunotherapy Group, Biomedical Research Institute Hospital 12 de Octubre, Madrid, Spain;d H12O-CNIO Cancer Immunotherapy Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spainhttps://orcid.org/0000-0001-8229-1881View further author information
, Marta Comptef Department of Antibody Engineering, Leadartis SL, Madrid, Spainhttps://orcid.org/0000-0002-7138-9266View further author information
, Shaukat Khang Nemours Children’s Health Delaware, Wilmington, Delaware, USAView further author information
, Takeshi Tsudag Nemours Children’s Health Delaware, Wilmington, Delaware, USAView further author information
, Patrick Chamesh Aix Marseille Univ, CNRS, INSERM, Institute Paoli-Calmettes, CRCM, Marseille, Francehttps://orcid.org/0000-0002-6104-6286View further author information
, Javier Lacadenae Department of Biochemistry and Molecular Biology, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Madrid, Spainhttps://orcid.org/0000-0002-7314-0333View further author information
, Luis Álvarez-Vallinab Cancer Immunotherapy Unit (UNICA), Hospital Universitario 12 de Octubre, Madrid, Spain;c Immuno-oncology and Immunotherapy Group, Biomedical Research Institute Hospital 12 de Octubre, Madrid, Spain;d H12O-CNIO Cancer Immunotherapy Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spainhttps://orcid.org/0000-0003-3053-6757View further author information
& Laura Sanza Molecular Immunology Unit, Biomedical Research Institute Hospital Universitario Puerta de Hierro Majadahonda, Madrid, SpainCorrespondence[email protected]
https://orcid.org/0000-0002-3119-3218View further author information
show allhttps://orcid.org/0000-0002-3119-3218View further author information
Article: 2338558
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Received 07 Nov 2023, Accepted 30 Mar 2024, Published online: 13 Apr 2024
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