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Volume 1, Issue 4

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 1, Issue 4 (2006)

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Expert Opinion on Drug Discovery, Volume 1, Issue 4 (2006)

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Editorial

Article

Antisense oligonucleotide technologies in drug discovery

Tarek Aboul-Fadl

Pages: 285-288

Published online: 06 Sep 2006

AbstractforAntisense oligonucleotide technologies in drug discovery | Full Text | References | PDF (1.8 MB)

80 Views
8 CrossRef citations
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Reviews

Article

Application of microdialysis for pharmacokinetic-pharmacodynamic modelling

Christian Höcht, Javier AW Opezzo, Guillermo F. Bramuglia & Carlos A. Taira

Pages: 289-301

Published online: 06 Sep 2006

AbstractforApplication of microdialysis for pharmacokinetic-pharmacodynamic modelling | PDF (5.9 MB)

123 Views
9 CrossRef citations
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Article

The h-P2X3 glycoprotein receptor as an example of integrating bioinformatics and structural research

Peter P Mager & Peter Illes

Pages: 303-309

Published online: 06 Sep 2006

AbstractforThe h-P2X3 glycoprotein receptor as an example of integrating bioinformatics and structural research | Full Text | References | PDF (5.5 MB)

74 Views
4 CrossRef citations
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Article

Leadhopping – and beyond

Richard D Cramer

Pages: 311-321

Published online: 06 Sep 2006

AbstractforLeadhopping – and beyond | Full Text | References | PDF (8 MB)

48 Views
8 CrossRef citations
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Article

Animal models of pain for drug discovery

Shailen K Joshi & Prisca Honore

Pages: 323-334

Published online: 06 Sep 2006

AbstractforAnimal models of pain for drug discovery | Full Text | References | PDF (6.2 MB)

252 Views
17 CrossRef citations
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Article

Incorporating protein flexibility into docking and structure-based drug design

Xavier Barril & Xavier Fradera

Pages: 335-349

Published online: 06 Sep 2006

AbstractforIncorporating protein flexibility into docking and structure-based drug design | Full Text | References | PDF (7.6 MB)

120 Views
27 CrossRef citations
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Technology Evaluation

Article

SiDMAP: a metabolomics approach to assess the effects of drug candidates on the dynamic properties of biochemical pathways

Greg Maguire, Paul Lee, David Manheim & Laszlo Boros

Pages: 351-359

Published online: 06 Sep 2006

AbstractforSiDMAP: a metabolomics approach to assess the effects of drug candidates on the dynamic properties of biochemical pathways | Full Text | References | PDF (3.9 MB)

106 Views
12 CrossRef citations
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Meeting Highlights

Article

Trends in drug discovery technologies – conference report from MipTec 2006

8 – 11 May 2006, Basel, Switzerland

Martin Klumpp & Lorenz M Mayr

Pages: 361-364

Published online: 06 Sep 2006

AbstractforTrends in drug discovery technologies – conference report from MipTec 2006 | Full Text | References | PDF (3.4 MB)

42 Views
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Article

MipTec conference session report – maximising compound value

8 – 11 May 2006, Basel, Switzerland

Ian Yates

Pages: 365-367

Published online: 06 Sep 2006

First Page PreviewforMipTec conference session report – maximising compound value | Full Text | PDF (1.1 MB)

30 Views
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Article

The impact of preclinical drug safety on R&D productivity

23 – 25 May 2006, Philadelphian Convention Centre, USA

Orest Hurko

Pages: 369-372

Published online: 06 Sep 2006

AbstractforThe impact of preclinical drug safety on R&D productivity | Full Text | References | PDF (1.9 MB)

51 Views
1 CrossRef citations
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Article

Cell-based assays for high-throughput screening

23 – 25 May 2006, Pennsylvania Convention Center, Philadelphia, Pennsylvania, USA

Frank H Büttner

Pages: 373-378

Published online: 06 Sep 2006

AbstractforCell-based assays for high-throughput screening | Full Text | References | PDF (5.2 MB)

200 Views
6 CrossRef citations
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