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Volume 11, Issue 12

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 11, Issue 12 (2016)

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Expert Opinion on Drug Discovery, Volume 11, Issue 12 (2016)

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Editorial

Minipigs as models in drug discovery

Vijay K. Singh, Karla D. Thrall & Martin Hauer-Jensen

Pages: 1131-1134

Published online: 22 Aug 2016

First Page PreviewforMinipigs as models in drug discovery | Full Text | References | PDF (500.6 KB)

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Editorial

Should network biology be used for drug discovery?

Francisco Martínez-Jiménez & Marc A. Marti-Renom

Pages: 1135-1137

Published online: 23 Sep 2016

First Page PreviewforShould network biology be used for drug discovery? | Full Text | References | PDF (461.2 KB)

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Review

Centipede venoms as a source of drug leads

Eivind A.B. Undheim, Ronald A. Jenner & Glenn F. King

Pages: 1139-1149

Published online: 19 Sep 2016

AbstractforCentipede venoms as a source of drug leads | Full Text | References | PDF (1.3 MB)

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Review

Discovery and optimization of peptide macrocycles

Andrew M. White & David J. Craik

Pages: 1151-1163

Published online: 16 Oct 2016

AbstractforDiscovery and optimization of peptide macrocycles | Full Text | References | PDF (1.6 MB)

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Review

Structure-based discovery and binding site analysis of histamine receptor ligands

Róbert Kiss & György M. Keserű

Pages: 1165-1185

Published online: 16 Oct 2016

AbstractforStructure-based discovery and binding site analysis of histamine receptor ligands | Full Text | References | PDF (2.7 MB)

464 Views
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Review

Recent advances in targeting the fatty acid biosynthetic pathway using fatty acid synthase inhibitors

Thelma S. Angeles & Robert L. Hudkins

Pages: 1187-1199

Published online: 18 Oct 2016

AbstractforRecent advances in targeting the fatty acid biosynthetic pathway using fatty acid synthase inhibitors | Full Text | References | PDF (1.4 MB)

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Review

Approaches for targeting cancer stem cells drug resistance

Roberta Rosa, Valentina D’Amato, Sabino De Placido & Roberto Bianco

Pages: 1201-1212

Published online: 14 Oct 2016

AbstractforApproaches for targeting cancer stem cells drug resistance | Full Text | References | PDF (1.2 MB)

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Review

In silico frameworks for systematic pre-clinical screening of potential anti-leukemia therapeutics

Matthew H. Ung, Frederick S. Varn & Chao Cheng

Pages: 1213-1222

Published online: 11 Oct 2016

AbstractforIn silico frameworks for systematic pre-clinical screening of potential anti-leukemia therapeutics | Full Text | References | PDF (929.5 KB)

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Review

Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target

David R. Janero & Ganesh A. Thakur

Pages: 1223-1237

Published online: 21 Oct 2016

AbstractforLeveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target | Full Text | References | PDF (1.6 MB)

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