Expert Opinion on Drug Discovery, Volume 12, Issue 12 (2017)

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Expert Opinion on Drug Discovery, Volume 12, Issue 12 (2017)

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Editorial

Editorial
What’s next for chronobiology and drug discovery
Zheng Chen
Pages: 1181-1185
Published online: 11 Sep 2017
First Page PreviewforWhat’s next for chronobiology and drug discovery | Full Text | References | PDF (611 KB)
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Free Access

Review

Review
Animal models for autism in 2017 and the consequential implications to drug discovery
Kathryn K. Chadman
Pages: 1187-1194
Published online: 03 Oct 2017
AbstractforAnimal models for autism in 2017 and the consequential implications to drug discovery | Full Text | References | PDF (650.2 KB)
  • 662 Views
  • 29 CrossRef citations
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Review
Discovery methods of coagulation-inhibiting drugs
Antonio Gómez-Outes, Minerva García-Fuentes & Mª Luisa Suárez-Gea
Pages: 1195-1205
Published online: 27 Sep 2017
AbstractforDiscovery methods of coagulation-inhibiting drugs | Full Text | References | PDF (1.1 MB)
  • 736 Views
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Review
Novel CNS drug discovery and development approach: model-based integration to predict neuro-pharmacokinetics and pharmacodynamics
Elizabeth C. M. de Lange, Willem van den Brink, Yumi Yamamoto, Wilhelmus E. A. de Witte & Yin Cheong Wong
Pages: 1207-1218
Published online: 21 Sep 2017
AbstractforNovel CNS drug discovery and development approach: model-based integration to predict neuro-pharmacokinetics and pharmacodynamics | Full Text | References | PDF (1.5 MB)
  • 8620 Views
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Open Access
Review
Absorption sites of orally administered drugs in the small intestine
Teruo Murakami
Pages: 1219-1232
Published online: 17 Sep 2017
AbstractforAbsorption sites of orally administered drugs in the small intestine | Full Text | References | PDF (1.1 MB)
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Review
Recent developments with rhodanine as a scaffold for drug discovery
Danylo Kaminskyy, Anna Kryshchyshyn & Roman Lesyk
Pages: 1233-1252
Published online: 11 Oct 2017
AbstractforRecent developments with rhodanine as a scaffold for drug discovery | Full Text | References | PDF (3.2 MB)
  • 453 Views
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Review
Approaches for multi-gram scale isolation of enantiomers for drug discovery
Daniela Rossi, Marilù Tarantino, Giacomo Rossino, Marta Rui, Markus Juza & Simona Collina
Pages: 1253-1269
Published online: 03 Oct 2017
AbstractforApproaches for multi-gram scale isolation of enantiomers for drug discovery | Full Text | References | PDF (3 MB)
  • 263 Views
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Review
Mass spectrometry methods to study protein-metabolite interactions
Hongbo Guo, Hui Peng & Andrew Emili
Pages: 1271-1280
Published online: 21 Sep 2017
AbstractforMass spectrometry methods to study protein-metabolite interactions | Full Text | References | PDF (929 KB)
  • 599 Views
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Drug Discovery Case History

Article
Discovery and development of tramadol for the treatment of pain
Lidia Bravo, Juan Antonio Mico & Esther Berrocoso
Pages: 1281-1291
Published online: 17 Sep 2017
AbstractforDiscovery and development of tramadol for the treatment of pain | Full Text | References | PDF (985.1 KB)
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