Expert Opinion on Drug Discovery, Volume 12, Issue 5 (2017)

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Expert Opinion on Drug Discovery, Volume 12, Issue 5 (2017)

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Editorial

Editorial
The utility of target-based discovery
Glenn E. Croston
Pages: 427-429
Published online: 23 Mar 2017
First Page PreviewforThe utility of target-based discovery | Full Text | References | PDF (331.5 KB)
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Review

Review
Harnessing the power of proteomics for identification of oncogenic, druggable signalling pathways in cancer
Heather C. Murray, Matthew D. Dun & Nicole M. Verrills
Pages: 431-447
Published online: 17 Mar 2017
AbstractforHarnessing the power of proteomics for identification of oncogenic, druggable signalling pathways in cancer | Full Text | References | PDF (1.7 MB)
  • 566 Views
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Review
Selective targeting of epigenetic reader domains
Holger Greschik, Roland Schüle & Thomas Günther
Pages: 449-463
Published online: 14 Mar 2017
AbstractforSelective targeting of epigenetic reader domains | Full Text | References | PDF (1.8 MB)
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Review
Approaches for targeting self-renewal pathways in cancer stem cells: implications for hematological treatments
Gillian A. Horne & Mhairi Copland
Pages: 465-474
Published online: 14 Mar 2017
AbstractforApproaches for targeting self-renewal pathways in cancer stem cells: implications for hematological treatments | Full Text | References | PDF (897.9 KB)
  • 272 Views
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Review
Using natural products for drug discovery: the impact of the genomics era
Mingzi M Zhang, Yuan Qiao, Ee Lui Ang & Huimin Zhao
Pages: 475-487
Published online: 14 Mar 2017
AbstractforUsing natural products for drug discovery: the impact of the genomics era | Full Text | References | PDF (1.4 MB)
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Review
Genome database mining for the discovery of novel lantibiotics
Stephanie K. Sandiford
Pages: 489-495
Published online: 22 Mar 2017
AbstractforGenome database mining for the discovery of novel lantibiotics | Full Text | References | PDF (625.3 KB)
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Review
Challenges in searching for therapeutics against Botulinum Neurotoxins
Marco Pirazzini & Ornella Rossetto
Pages: 497-510
Published online: 17 Mar 2017
AbstractforChallenges in searching for therapeutics against Botulinum Neurotoxins | Full Text | References | PDF (1.7 MB)
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Review
An overview of Ca2+ mobilization assays in GPCR drug discovery
Qiang Ma, Lingyan Ye, Hongxia Liu, Ying Shi & Naiming Zhou
Pages: 511-523
Published online: 17 Mar 2017
AbstractforAn overview of Ca2+ mobilization assays in GPCR drug discovery | Full Text | References | PDF (1.5 MB)
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Drug Discovery Case History

Article
The preclinical discovery and development of quetiapine for the treatment of mania and depression
Aline Silva de Miranda, Fabrício A. Moreira & Antônio Lúcio Teixeira
Pages: 525-535
Published online: 14 Mar 2017
AbstractforThe preclinical discovery and development of quetiapine for the treatment of mania and depression | Full Text | References | PDF (910.5 KB)
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