Expert Opinion on Drug Discovery, Volume 15, Issue 10 (2020)

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Expert Opinion on Drug Discovery, Volume 15, Issue 10 (2020)

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Editorial

Editorial
Can quantitative pharmacology improve productivity in pharmaceutical research and development?
Mayankbhai Patel & Tjerk Bueters
Pages: 1111-1114
Published online: 08 Jun 2020
First Page PreviewforCan quantitative pharmacology improve productivity in pharmaceutical research and development? | Full Text | References | PDF (158.2 KB) | EPUB
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Editorial
The increasing impact of Chinese innovative drug research on the global stage with a focus on drug discovery
Wei Luo, Cherukupalli Srinivasulu, Xia Hao, Xinyong Liu & Peng Zhan
Pages: 1115-1120
Published online: 17 Jun 2020
First Page PreviewforThe increasing impact of Chinese innovative drug research on the global stage with a focus on drug discovery | Full Text | References | PDF (1.4 MB) | EPUB
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Drug Discovery Case History

Article
The preclinical discovery and development of agomelatine for the treatment of depression
George Konstantakopoulos, Stefanos Dimitrakopoulos & Panayiota G. Michalopoulou
Pages: 1121-1132
Published online: 22 Jun 2020
AbstractforThe preclinical discovery and development of agomelatine for the treatment of depression | Full Text | References | PDF (593.2 KB) | EPUB
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Perspective

What place does molecular topology have in today’s drug discovery?
Riccardo Zanni, Maria Galvez-Llompart, Ramon Garcia-Domenech & Jorge Galvez
Pages: 1133-1144
Published online: 04 Jun 2020
AbstractforWhat place does molecular topology have in today’s drug discovery? | Full Text | References | PDF (1.3 MB) | EPUB
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Review

Developments in the discovery and design of intranasal antidepressants
Małgorzata Panek, Paweł Kawalec, Andrzej Pilc & Władysław Lasoń
Pages: 1145-1164
Published online: 21 Jun 2020
AbstractforDevelopments in the discovery and design of intranasal antidepressants | Full Text | References | PDF (634.7 KB) | EPUB
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The application of machine learning techniques to innovative antibacterial discovery and development
Mateus Sá Magalhães Serafim, Thales Kronenberger, Patrícia Rufino Oliveira, Antti Poso, Káthia Maria Honório, Bruno Eduardo Fernandes Mota & Vinícius Gonçalves Maltarollo
Pages: 1165-1180
Published online: 17 Jun 2020
AbstractforThe application of machine learning techniques to innovative antibacterial discovery and development | Full Text | References | PDF (860.5 KB) | EPUB
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Modeling percutaneous absorption for successful drug discovery and development
Hanumanth Srikanth Cheruvu, Xin Liu, Jeffrey E. Grice & Michael S. Roberts
Pages: 1181-1198
Published online: 25 Jun 2020
AbstractforModeling percutaneous absorption for successful drug discovery and development | Full Text | References | PDF (7.1 MB) | EPUB
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Phage display technology for target determination of small-molecule therapeutics: an update
Yoichi Takakusagi, Kaori Takakusagi, Kengo Sakaguchi & Fumio Sugawara
Pages: 1199-1211
Published online: 13 Jul 2020
AbstractforPhage display technology for target determination of small-molecule therapeutics: an update | Full Text | References | PDF (3.1 MB) | EPUB
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Open Access
Peptide-based targeting of connexins and pannexins for therapeutic purposes
Anne Caufriez, Denise Böck, Charlotte Martin, Steven Ballet & Mathieu Vinken
Pages: 1213-1222
Published online: 15 Jun 2020
AbstractforPeptide-based targeting of connexins and pannexins for therapeutic purposes | Full Text | References | PDF (952.3 KB) | EPUB
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Advances in the discovery and development of selective heme-displacing IDO1 inhibitors
Lijun Sun
Pages: 1223-1232
Published online: 22 Jun 2020
AbstractforAdvances in the discovery and development of selective heme-displacing IDO1 inhibitors | Full Text | References | PDF (782.6 KB) | EPUB
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