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Volume 8, Issue 10

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 8, Issue 10 (2013)

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Expert Opinion on Drug Discovery, Volume 8, Issue 10 (2013)

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Reviews

Review Article

Xenograft and genetically engineered mouse model systems of osteosarcoma and Ewing's sarcoma: tumor models for cancer drug discovery

Valerie B Sampson (Research Associate) BS PhD, Davida F Kamara (Senior Research Assistant II) BS MS & E Anders Kolb (Director) BS MD

Pages: 1181-1189

Published online: 12 Jul 2013

AbstractforXenograft and genetically engineered mouse model systems of osteosarcoma and Ewing's sarcoma: tumor models for cancer drug discovery | Full Text | References | PDF (283.1 KB)

364 Views
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Review Article

Use of zebrafish apoptosis assays for preclinical drug discovery

Patricia McGrath & Wen Lin Seng PhD

Pages: 1191-1202

Published online: 21 Aug 2013

AbstractforUse of zebrafish apoptosis assays for preclinical drug discovery | Full Text | References | PDF (824.5 KB)

369 Views
13 CrossRef citations
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Review Article

Physical and virtual screening methods for marine toxins and drug discovery targeting nicotinic acetylcholine receptors

Jordi Molgó (Senior researcher) DDS PhD DSci, Rómulo Aráoz (Researcher) PhD, Evelyne Benoit (Researcher) PhD & Bogdan I Iorga (Researcher) PhD

Pages: 1203-1223

Published online: 06 Aug 2013

AbstractforPhysical and virtual screening methods for marine toxins and drug discovery targeting nicotinic acetylcholine receptors | Full Text | References | PDF (1 MB)

310 Views
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Review Article

Predictive approaches to increase absorption of compounds during lead optimisation

Klara Valko (Principal Scientific Investigator) PhD, James Butler (Senior Scientific Investigator) PhD & Peter Eddershaw (Director Respiratory Translational Science) PhD

Pages: 1225-1238

Published online: 19 Jul 2013

AbstractforPredictive approaches to increase absorption of compounds during lead optimisation | Full Text | References | PDF (528.1 KB)

709 Views
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Review Article

The eradication of leprosy: molecular modeling techniques for novel drug discovery

Shanmugam Anusuya (Associate Professor & Head) BPharm MSc MPhil PhD & Jeyakumar Natarajan (Associate Professor) MSc PhD

Pages: 1239-1251

Published online: 07 Aug 2013

AbstractforThe eradication of leprosy: molecular modeling techniques for novel drug discovery | Full Text | References | PDF (385.8 KB)

189 Views
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Review Article

Design and optimization of drugs used to treat copper deficiency

Milorad Cakic, Zarko Mitic, Goran Nikolic, Ivan Savic & Ivana M Savic

Pages: 1253-1263

Published online: 06 Aug 2013

AbstractforDesign and optimization of drugs used to treat copper deficiency | Full Text | References | PDF (286.4 KB)

236 Views
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Review Article

Small RNA drugs for prion disease: a new frontier

Amrit S Boese (PhD Student) BSc, Anna Majer (PhD Student) MSc, Reuben Saba (Post-Doctoral Fellow) PhD & Stephanie A Booth DPhil

Pages: 1265-1284

Published online: 13 Jul 2013

AbstractforSmall RNA drugs for prion disease: a new frontier | Full Text | References | PDF (655.9 KB)

352 Views
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Review Article

Novel approaches to drug design for the treatment of schizophrenia

Antoine Taly

Pages: 1285-1296

Published online: 19 Jul 2013

AbstractforNovel approaches to drug design for the treatment of schizophrenia | Full Text | References | PDF (794.7 KB)

501 Views
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Drug Discovery Case History

The preclinical profile of lurasidone: clinical relevance for the treatment of schizophrenia

Frank I Tarazi & Marco A Riva

Pages: 1297-1307

Published online: 10 Jul 2013

AbstractforThe preclinical profile of lurasidone: clinical relevance for the treatment of schizophrenia | Full Text | References | PDF (312.6 KB)

570 Views
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Research Article

Article

Page: i

Published online: 21 Sep 2013

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