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‘Latest articles’ are articles accepted for publication in this journal but not yet published in a volume/issue. Articles are removed from the ‘Latest articles’ list when they are published in a volume/issue. Latest articles are citable using the author(s), year of online publication, article title, journal and article DOI.

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Original Research

Article
Safety, pharmacokinetics and pharmacodynamics of SHR-1703, an innovative long-acting anti-interleukin-5 monoclonal antibody, in healthy subjects: a randomized, double-blind, dose-escalation, placebo-controlled phase I study
Ling Yang, Yuan Fang, Yuan Luo, Meng Fu, Kai Shen & Zhu Luo
Published online: 03 Jun 2024
  • 11 Views
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Review

Review Article
The role of extracellular vesicles in immune cell exhaustion and resistance to immunotherapy
Ava Aghakhani, Parmida Sadat Pezeshki & Nima Rezaei
Published online: 30 May 2024
  • 47 Views
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Review

Review Article
Clinical application and potential pluripotent effects of hepatocyte growth factor in spinal cord injury regeneration
Shogo Hashimoto, Narihito Nagoshi, Masaya Nakamura & Hideyuki Okano
Published online: 29 May 2024
  • 20 Views
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Review

Review Article
Inflammation and Huntington’s disease – a neglected therapeutic target?
Sophie E. Field, Annabel J. Curle & Roger A. Barker
Published online: 29 May 2024
  • 126 Views
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Open Access

Plain Language Summary

Plain Language Summary of Publication
Plain Language Summary of the PAISLEY study: deucravacitinib as a treatment for people with systemic lupus erythematosus
Eric F. Morand, Marilyn Pike, J Merrill, Ronald F van Vollenhoven, Victoria P Werth, Coburn Hobar, Nikolay Delev, Vaishali Shah, Brian Sharkey, Thomas Wegman, Ian Catlett, Subhashis Banerjee & Shalabh Singhal
Published online: 29 May 2024
  • 175 Views
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Open Access

Review

Review Article
Epidermal growth factor receptor antagonists in colorectal cancer: emerging strategies for precision therapy
Nadia Saoudi González, Paola Valeria Marchese, Iosune Baraibar, Javier Ros, Francesc Salvà, Marta Rodríguez, Clara Salvà, Caterina Vaghi, Adriana Alcaraz, Ariadna García, Josep Tabernero & Elena Élez
Published online: 22 May 2024
  • 37 Views
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Review

Review Article
Novel investigational drugs for alopecia areata and future perspectives
Ivana Chim, Ragini Ghiya, Rodney D Sinclair & Samantha Eisman
Published online: 20 May 2024
  • 213 Views
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Review

Review Article
Drugs in preclinical and early clinical development for the treatment of Chagas´s disease: the current status
Fernanda Karoline Vieira da Silva Torchelsen, Ana Lia Mazzeti & Vanessa Carla Furtado Mosqueira
Published online: 14 May 2024
  • 56 Views
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Review

Review Article
Therapeutic potential of cannabidiol (CBD) in the treatment of cardiovascular diseases
Nadia Martinez Naya, Jazmin Kelly, Austin Hogwood, Antonio Abbate & Stefano Toldo
Published online: 09 May 2024
  • 72 Views
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Review

Review Article
From bench to bedside - is there a role of IL-17 drugs in rheumatoid arthritis?
Swetha Byravan, Harini Samarasinghe, Jack Shi Jie Yuan, Syed Haider Tahir, Arumugam Moorthy & Hasan Tahir
Published online: 09 May 2024
  • 30 Views
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Review

Review Article
Frontotemporal dementia: from genetics to therapeutic approaches
Francesca R. Buccellato, Marianna D’Anca, Gianluca Martino Tartaglia, Massimo Del Fabbro & Daniela Galimberti
Published online: 09 May 2024
  • 850 Views
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Open Access

Review

Review Article
Therapies in preclinical and in early clinical development for the treatment of urinary tract infections: from pathogens to therapies
Virginia Fuochi, Salvatore Furnari, Laura Trovato, Maddalena Calvo & Pio Maria Furneri
Published online: 09 May 2024
  • 26 Views
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Review

Review Article
Emerging therapies for overactive bladder: preclinical, phase I and phase II studies
Samantha Gibson & Pamela Ellsworth
Published online: 09 May 2024
  • 36 Views
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Editorial

Editorial
Will new investigational drugs change the way we treat Charcot-Marie-Tooth disease?
Amedeo De Grado, Chiara Pisciotta, Paola Saveri & Davide Pareyson
Published online: 08 May 2024
  • 227 Views
  • 0 CrossRef citations
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Free Access

Special Report

Report
Investigational bispecific antibodies for the treatment of rheumatoid arthritis
Aliki I. Venetsanopoulou, Paraskevi V. Voulgari & Alexandros A. Drosos
Published online: 08 May 2024
  • 78 Views
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Review

Review Article
Prospects of focal adhesion kinase inhibitors as a cancer therapy in preclinical and early phase study
Jiaming Gao, Jingwen Cheng, Wanyu Xie, Ping Zhang, Xuebin Liu, Zaiqi Wang & Baoyuan Zhang
Published online: 08 May 2024
  • 61 Views
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Editorial

Editorial
Lepodisiran, an siRNA targeting lipoprotein(a) for the potential future treatment of cardiovascular disease
P. Mihika S. Fernando, Amanda J. Hooper & John R. Burnett
Published online: 08 May 2024
  • 316 Views
  • 0 CrossRef citations
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Free Access

Special Report

Report
The role of phosphodiesterase 9A inhibitors in heart failure
Saam Foroshani, Avrohom Karp, Wilbert S. Aronow & Gregg M. Lanier
Published online: 08 May 2024
  • 21 Views
  • 0 CrossRef citations
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Review

Review Article
Investigational farnesoid X receptor agonists for the treatment of primary biliary cholangitis
Prithvi Reddy Akepati & Eric M. Gochanour
Published online: 07 May 2024
  • 59 Views
  • 0 CrossRef citations
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Original Research

Article
Safety, tolerability, and pharmacokinetics of the novel RdRp inhibitor SHEN26 against SARS-CoV-2: a randomized, placebo-controlled, double-blind Phase I study in healthy subjects
Cheng Sun, Hao Liu, Ziwei Ouyang, Jie Ding, Qin Zhang, Hongjie Ma, Dandan Xu, Qian Zhang, Renpeng Zhou, Mingming Yang & Wei Hu
Published online: 30 Apr 2024
  • 38 Views
  • 0 CrossRef citations
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Review

Review Article
Investigational drugs for the treatment of acromegaly: new agents to transform therapy
Rosa Pirchio, Renata S. Auriemma, Alice Vergura, Rosario Pivonello & Annamaria Colao
Published online: 30 Apr 2024
  • 74 Views
  • 0 CrossRef citations
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Editorial

Editorial
Targeting diarrhea-predominant irritable bowel syndrome: hopes or hypes?
Gabrio Bassotti
Published online: 25 Apr 2024
  • 146 Views
  • 0 CrossRef citations
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Free Access

Review Article

Review Article
Interleukin antagonists for atopic dermatitis: a new era of therapy
Aikaterini Tsiogka, Eleni Paschou, Dimitra Koumaki, Efstratios Vakirlis & Stamatios Gregoriou
Accepted author version posted online: 24 Apr 2024
  • 183 Views
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Review

Review Article
Sodium/bile acid co-transporter inhibitors currently in preclinical or early clinical development for the treatment of primary biliary cholangitis
Abhishek Gairola, Aaron Wetten & Jessica Dyson
Published online: 24 Apr 2024
  • 45 Views
  • 0 CrossRef citations
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Review

Review Article
Investigational agents for autosomal dominant polycystic kidney disease: preclinical and early phase study insights
Irene Capelli, Sarah Lerario, Francesca Ciurli, Gian Marco Berti, Valeria Aiello, Michele Provenzano & Gaetano La Manna
Published online: 21 Apr 2024
  • 174 Views
  • 0 CrossRef citations
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Review

Review Article
Experimental and new investigational drugs for the treatment of uterine fibroids
Giulio Evangelisti, Simone Ferrero, Umberto Perrone, Claudio Gustavino, Eugenio Volpi, Alberto Izzotti & Fabio Barra
Published online: 17 Apr 2024
  • 97 Views
  • 0 CrossRef citations
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Review

Review Article
Novel carbonic anhydrase inhibitors for the treatment of Helicobacter pylori infection
Claudiu T. Supuran
Published online: 27 Mar 2024
  • 60 Views
  • 0 CrossRef citations
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