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Expert Opinion on Drug Metabolism & Toxicology
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Volume 1, Issue 3

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 1, Issue 3 (2005)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 1, Issue 3 (2005)

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Review

Article

Pharmacodynamics of antimicrobials: treatment optimisation

Effie L Gillespie, Joseph L Kuti & David P Nicolau

Pages: 351-361

Published online: 29 Sep 2005

AbstractforPharmacodynamics of antimicrobials: treatment optimisation | References | PDF (142.9 KB)

121 Views
19 CrossRef citations
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Article

Metabonomics in preclinical drug development

Donald G Robertson, Michael D Reily & J David Baker

Pages: 363-376

Published online: 29 Sep 2005

AbstractforMetabonomics in preclinical drug development | References | PDF (201 KB)

70 Views
33 CrossRef citations
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Article

Screening the receptorome reveals molecular targets responsible for drug-induced side effects: focus on ‘fen–phen’

Vincent Setola & Bryan L Roth

Pages: 377-387

Published online: 29 Sep 2005

AbstractforScreening the receptorome reveals molecular targets responsible for drug-induced side effects: focus on ‘fen–phen’ | References | PDF (156.8 KB)

178 Views
36 CrossRef citations
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Article

Role of inflammation in the mechanism of acetaminophen-induced hepatotoxicity

Hartmut Jaeschke

Pages: 389-397

Published online: 29 Sep 2005

AbstractforRole of inflammation in the mechanism of acetaminophen-induced hepatotoxicity | References | PDF (112.2 KB)

272 Views
77 CrossRef citations
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Article

Novel mechanisms of nonsteroidal anti-inflammatory drug-induced renal toxicity

Kathleen M Knights, Paraskevi Tsoutsikos & John O Miners

Pages: 399-408

Published online: 29 Sep 2005

AbstractforNovel mechanisms of nonsteroidal anti-inflammatory drug-induced renal toxicity | References | PDF (304.8 KB)

215 Views
22 CrossRef citations
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Article

Use of in vitro transporter assays to understand hepatic and renal disposition of new drug candidates

Jasminder Sahi

Pages: 409-427

Published online: 29 Sep 2005

AbstractforUse of in vitro transporter assays to understand hepatic and renal disposition of new drug candidates | References | PDF (254.5 KB)

202 Views
22 CrossRef citations
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Article

Role of the liver-specific transporters OATP1B1 and OATP1B3 in governing drug elimination

Nicola F Smith, William D Figg & Alex Sparreboom

Pages: 429-445

Published online: 29 Sep 2005

AbstractforRole of the liver-specific transporters OATP1B1 and OATP1B3 in governing drug elimination | References | PDF (218.2 KB)

835 Views
118 CrossRef citations
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Article

Differences in absorption, distribution, metabolism and excretion of xenobiotics between the paediatric and adult populations

M Strolin Benedetti, R Whomsley & E L Baltes

Pages: 447-471

Published online: 29 Sep 2005

AbstractforDifferences in absorption, distribution, metabolism and excretion of xenobiotics between the paediatric and adult populations | References | PDF (265.5 KB)

779 Views
104 CrossRef citations
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Article

Pharmacokinetic drug interactions with non-nucleoside reverse transcriptase inhibitors

Qing Ma, Olanrewaju O Okusanya, Patrick F Smith, Robert DiCenzo, Judianne C Slish, Linda M Catanzaro, Alan Forrest & Gene D Morse

Pages: 473-485

Published online: 29 Sep 2005

AbstractforPharmacokinetic drug interactions with non-nucleoside reverse transcriptase inhibitors | References | PDF (158.3 KB)

161 Views
34 CrossRef citations
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Article

Pharmacogenetic differences and drug–drug interactions in immunosuppressive therapy

Jill S Warrington & Leslie M Shaw

Pages: 487-503

Published online: 29 Sep 2005

AbstractforPharmacogenetic differences and drug–drug interactions in immunosuppressive therapy | References | PDF (172.3 KB)

158 Views
19 CrossRef citations
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Drug Evaluation

Article

Mycophenolate mofetil in organ transplantation: focus on metabolism, safety and tolerability

Maria Shipkova, Victor William Armstrong, Michael Oellerich & Eberhard Wieland

Pages: 505-526

Published online: 29 Sep 2005

AbstractforMycophenolate mofetil in organ transplantation: focus on metabolism, safety and tolerability | References | PDF (272.9 KB)

280 Views
74 CrossRef citations
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Article

Donepezil: a review

Ben Seltzer

Pages: 527-536

Published online: 29 Sep 2005

AbstractforDonepezil: a review | References | PDF (115.7 KB)

1068 Views
80 CrossRef citations
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Technology Evaluation

Article

Theragenomic knowledge management for individualised safety of drugs, chemicals, pollutants and dietary ingredients

Joseph Gut & Dario Bagatto

Pages: 537-554

Published online: 29 Sep 2005

AbstractforTheragenomic knowledge management for individualised safety of drugs, chemicals, pollutants and dietary ingredients | References | PDF (388 KB)

35 Views
6 CrossRef citations
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Article

truPK – human pharmacokinetic models for quantitative ADME prediction

Kalyanasundaram Subramanian

Pages: 555-564

Published online: 29 Sep 2005

AbstractfortruPK – human pharmacokinetic models for quantitative ADME prediction | References | PDF (147.4 KB)

117 Views
8 CrossRef citations
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Meeting Highlights

Article

Predictive ADME-Tox

London, UK, 27 – 28 April 2005

Jennifer Fostel

Pages: 565-570

Published online: 29 Sep 2005

AbstractforPredictive ADME-Tox | References | PDF (126.8 KB)

49 Views
5 CrossRef citations
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