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Volume 10, Issue 11

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 10, Issue 11 (2014)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 10, Issue 11 (2014)

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Reviews

Review Article

Pharmacokinetic and pharmacodynamic interactions between antiepileptics and antidepressants

Domenico Italiano, Edoardo Spina (Professor) & Jose de Leon

Pages: 1457-1489

Published online: 06 Sep 2014

AbstractforPharmacokinetic and pharmacodynamic interactions between antiepileptics and antidepressants | Full Text | References | PDF (813.5 KB)

1006 Views
45 CrossRef citations
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Review Article

Improved brain uptake of peptide-based CNS drugs via alternative routes of administrations of its nanocarrier delivery systems: a promising strategy for CNS targeting delivery of peptides

Shuai Qian, Qianwen Wang & Zhong Zuo

Pages: 1491-1508

Published online: 06 Sep 2014

AbstractforImproved brain uptake of peptide-based CNS drugs via alternative routes of administrations of its nanocarrier delivery systems: a promising strategy for CNS targeting delivery of peptides | Full Text | References | PDF (389.6 KB)

378 Views
10 CrossRef citations
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Review Article

Novel strategies for the treatment of migraine attacks via the CGRP, serotonin, dopamine, PAC1, and NMDA receptors

János Tajti (Associate Professor of Clinical Neurology) MD PhD, Anett Csáti (Resident in Clinical Neurology) MD PhD & László Vécsei (Member of the Hungarian Academy of Sciences, Head of the Department of Neurology) MD PhD DSc

Pages: 1509-1520

Published online: 25 Sep 2014

AbstractforNovel strategies for the treatment of migraine attacks via the CGRP, serotonin, dopamine, PAC1, and NMDA receptors | Full Text | References | PDF (365.6 KB)

604 Views
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Review Article

Pregnane X receptor and drug-induced liver injury

Yue-Ming Wang (Senior Research Technologist at HTS Center) PhD, Sergio C Chai (HTS Specialist) PhD, Christopher T Brewer & Taosheng Chen (Associate Member) PhD

Pages: 1521-1532

Published online: 25 Sep 2014

AbstractforPregnane X receptor and drug-induced liver injury | Full Text | References | PDF (471.6 KB)

586 Views
41 CrossRef citations
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Review Article

Effect of drug transporter pharmacogenetics on cholestasis

Christoph G Dietrich & Andreas Geier (Professor of Medicine and Hepatology) MD

Pages: 1533-1551

Published online: 26 Sep 2014

AbstractforEffect of drug transporter pharmacogenetics on cholestasis | Full Text | References | PDF (514.3 KB)

465 Views
16 CrossRef citations
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Review Article

Competency of different cell models to predict human hepatotoxic drugs

M José Gómez-Lechón (Senior Researcher) PhD, Laia Tolosa (Research Assistant) PhD, Isabel Conde (Associated Clinical Collaborator) & M Teresa Donato (Senior Researcher) PhD

Pages: 1553-1568

Published online: 09 Oct 2014

AbstractforCompetency of different cell models to predict human hepatotoxic drugs | Full Text | References | PDF (527.4 KB)

1788 Views
136 CrossRef citations
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Review Article

Interethnic variability of CYP2D6 alleles and of predicted and measured metabolic phenotypes across world populations

Adrián LLerena, Maria Eugenia G Naranjo, Fernanda Rodrigues-Soares, Eva M Penas-LLedó, Humberto Fariñas & Eduardo Tarazona-Santos

Pages: 1569-1583

Published online: 14 Oct 2014

AbstractforInterethnic variability of CYP2D6 alleles and of predicted and measured metabolic phenotypes across world populations | Full Text | References | PDF (400.1 KB)

1021 Views
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Drug Evaluations

Tacrolimus in pancreas transplant: a focus on toxicity, diabetogenic effect and drug–drug interactions

Erika B Rangel

Pages: 1585-1605

Published online: 26 Sep 2014

AbstractforTacrolimus in pancreas transplant: a focus on toxicity, diabetogenic effect and drug–drug interactions | Full Text | References | PDF (582.7 KB) | Supplemental

505 Views
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An update on the safety and efficacy of regorafenib in the treatment of solid cancers

Stephen L Chan & Brigette BY Ma (Associate Professor)

Pages: 1607-1614

Published online: 14 Oct 2014

AbstractforAn update on the safety and efficacy of regorafenib in the treatment of solid cancers | Full Text | References | PDF (238.4 KB)

490 Views
7 CrossRef citations
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Research Article

Article

Page: i

Published online: 14 Oct 2014

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