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Volume 10, Issue 12

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 10, Issue 12 (2014)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 10, Issue 12 (2014)

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Meta-Opinion

Article

The debate on animal ADME studies in drug development: an update

Mario Pellegatti

Pages: 1615-1620

Published online: 06 Nov 2014

AbstractforThe debate on animal ADME studies in drug development: an update | Full Text | References | PDF (170.5 KB)

519 Views
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Reviews

Review Article

Cell- and biomarker-based assays for predicting nephrotoxicity

Johnny X Huang (Research Officer) , Mark A Blaskovich (Senior Research Officer) & Matthew A Cooper (Professor)

Pages: 1621-1635

Published online: 10 Nov 2014

AbstractforCell- and biomarker-based assays for predicting nephrotoxicity | Full Text | References | PDF (420.1 KB)

1058 Views
42 CrossRef citations
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Review Article

Development of in vivo drug-induced neurotoxicity models

Hari S Sharma (Professor of Neurobiology (MRC), Docent in Neuroanatomy (UU), Director) Ph D, Preeti Menon, José Vicente Lafuente, Dafin F Muresanu, Z Ryan Tian, Ranjana Patnaik & Aruna Sharma

Pages: 1637-1661

Published online: 13 Oct 2014

AbstractforDevelopment of in vivo drug-induced neurotoxicity models | Full Text | References | PDF (2.2 MB)

408 Views
19 CrossRef citations
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Review Article

Green tea extract and the risk of drug-induced liver injury

Rolf Teschke, Li Zhang, Lena Melzer, Johannes Schulze & Axel Eickhoff

Pages: 1663-1676

Published online: 15 Oct 2014

AbstractforGreen tea extract and the risk of drug-induced liver injury | Full Text | References | PDF (291.6 KB)

531 Views
32 CrossRef citations
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Review Article

Natural compounds to overcome cancer chemoresistance: toxicological and clinical issues

Eleonora Turrini, Lorenzo Ferruzzi & Carmela Fimognari

Pages: 1677-1690

Published online: 23 Oct 2014

AbstractforNatural compounds to overcome cancer chemoresistance: toxicological and clinical issues | Full Text | References | PDF (388.9 KB)

302 Views
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Review Article

Effects of pharmaceutical PEGylation on drug metabolism and its clinical concerns

Xingwang Zhang (Postdoc.) PhD, Huan Wang, Zhiguo Ma & Baojian Wu (Professor) PhD

Pages: 1691-1702

Published online: 30 Sep 2014

AbstractforEffects of pharmaceutical PEGylation on drug metabolism and its clinical concerns | Full Text | References | PDF (659.8 KB)

1118 Views
67 CrossRef citations
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Review Article

Pharmacogenetics of etanercept: role of TNF-α gene polymorphisms in improving its efficacy

Giuseppe Murdaca, Francesca Spanò, Miriam Contatore, Andrea Guastalla, Ottavia Magnani & Francesco Puppo

Pages: 1703-1710

Published online: 10 Oct 2014

AbstractforPharmacogenetics of etanercept: role of TNF-α gene polymorphisms in improving its efficacy | Full Text | References | PDF (230.5 KB)

580 Views
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Review Article

Modulation of the pharmacokinetics, therapeutic and adverse effects of NSAIDs by Chinese herbal medicines

Sophia Yui Kau Fong PhD RPh, Thomas H Efferth (Professor) PhD & Zhong Zuo (Professor) PhD

Pages: 1711-1739

Published online: 11 Oct 2014

AbstractforModulation of the pharmacokinetics, therapeutic and adverse effects of NSAIDs by Chinese herbal medicines | Full Text | References | PDF (8.3 MB) | Supplemental

384 Views
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Drug Evaluations

Pharmacokinetic and pharmacodynamic evaluation of ceftaroline fosamil

Andrew Merker PharmD, Larry H Danziger (Professor) PharmD, Keith A Rodvold (Professor) PharmD & Robert C Glowacki (Clinical Assistant Professor) PharmD

Pages: 1741-1750

Published online: 27 Oct 2014

AbstractforPharmacokinetic and pharmacodynamic evaluation of ceftaroline fosamil | Full Text | References | PDF (284.5 KB)

596 Views
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Pharmacokinetic and pharmacodynamic profile of dronedarone, a new antiarrhythmic agent for the treatment of atrial fibrillation

Gian Marco Rosa, Daniele Bianco, Antonello Parodi, Alberto Valbusa, Camilla Zawaideh, Nicolò Bizzarri, Simone Ferrero & Claudio Brunelli

Pages: 1751-1764

Published online: 28 Oct 2014

AbstractforPharmacokinetic and pharmacodynamic profile of dronedarone, a new antiarrhythmic agent for the treatment of atrial fibrillation | Full Text | References | PDF (368.3 KB)

539 Views
11 CrossRef citations
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Research Article

Article

Page: i

Published online: 14 Nov 2014

42 Views
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Expert Opinion on Drug Metabolism & Toxicology (Vol.10, Iss.12, 2014)

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