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Volume 10, Issue 2

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 10, Issue 2 (2014)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 10, Issue 2 (2014)

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Editorial

Approaches for high-throughput pharmacokinetic screening of low-molecular-weight drug candidates

Stefano Fontana

Pages: 139-142

Published online: 13 Dec 2013

AbstractforApproaches for high-throughput pharmacokinetic screening of low-molecular-weight drug candidates | Full Text | References | PDF (139.7 KB)

1891 Views
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Reviews

Review Article

Assessment of nonsteroidal anti-inflammatory drug-induced cardiotoxicity

Bhulan Kumar Singh (Assistant Professor) MPharm, Syed Ehtaishamul Haque (Assistant Professor) MSc PhD & Krishna Kolappa Pillai (Professor and Head) MPharm PhD

Pages: 143-156

Published online: 12 Nov 2013

AbstractforAssessment of nonsteroidal anti-inflammatory drug-induced cardiotoxicity | Full Text | References | PDF (516.8 KB)

713 Views
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Review Article

Exploring concepts of in vitro time-dependent CYP inhibition assays

David M Stresser (Program Manager) PhD, Jialin Mao (Scientist) PhD, Jane R Kenny (Senior Scientist) , Barry C Jones (Senior Principal Scientist) & Kenneth Grime

Pages: 157-174

Published online: 21 Nov 2013

AbstractforExploring concepts of in vitro time-dependent CYP inhibition assays | Full Text | References | PDF (523.3 KB)

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Review Article

Antiplatelet drug interactions with proton pump inhibitors

Stuart A Scott (Assistant Professor) PhD, Aniwaa Owusu Obeng PharmD & Jean-Sébastien Hulot MD PhD

Pages: 175-189

Published online: 09 Nov 2013

AbstractforAntiplatelet drug interactions with proton pump inhibitors | Full Text | References | PDF (644.2 KB)

788 Views
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Review Article

Cytochrome P450 and ischemic heart disease: current concepts and future directions

Andrew Rowland (Lecturer) PhD & Arduino A Mangoni (Professor) PhD FRCP FRACP

Pages: 191-213

Published online: 25 Nov 2013

AbstractforCytochrome P450 and ischemic heart disease: current concepts and future directions | Full Text | References | PDF (492.6 KB)

261 Views
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Review Article

Use of density functional theory in drug metabolism studies

Patrik Rydberg, Flemming Steen Jørgensen & Lars Olsen

Pages: 215-227

Published online: 03 Dec 2013

AbstractforUse of density functional theory in drug metabolism studies | Full Text | References | PDF (657.3 KB)

484 Views
20 CrossRef citations
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Review Article

Pharmacokinetic and pharmacodynamic modeling for acute and chronic pain drug assessment

Haitao Yang (Assistant Professor) PhD, Yan Feng (Associate Director) PhD & Xu Steven Xu PhD

Pages: 229-248

Published online: 16 Jan 2014

AbstractforPharmacokinetic and pharmacodynamic modeling for acute and chronic pain drug assessment | Full Text | References | PDF (856.1 KB)

445 Views
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Review Article

Alterations in the CNS effects of anti-epileptic drugs by Chinese herbal medicines

Sophia Yui Kau Fong, Yin Cheong Wong & Zhong Zuo

Pages: 249-267

Published online: 13 Dec 2013

AbstractforAlterations in the CNS effects of anti-epileptic drugs by Chinese herbal medicines | Full Text | References | PDF (3.2 MB)

264 Views
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Drug Evaluations

PK evaluation of fondaparinux sodium for the treatment of thrombosis

Xavier Delavenne PharmD PhD, Paul Frappé MD, Paul Zufferey MD PhD, Patrick Mismetti MD PhD, Silvy Laporte MSc PhD & Laurent Bertoletti MD PhD

Pages: 269-277

Published online: 21 Dec 2013

AbstractforPK evaluation of fondaparinux sodium for the treatment of thrombosis | Full Text | References | PDF (263.8 KB)

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An evaluation of the pharmacokinetics and pharmacodynamics of ivabradine for the treatment of heart failure

Gian Marco Rosa, Simone Ferrero MD PhD, Paola Ghione, Alberto Valbusa & Claudio Brunelli

Pages: 279-291

Published online: 31 Dec 2013

AbstractforAn evaluation of the pharmacokinetics and pharmacodynamics of ivabradine for the treatment of heart failure | Full Text | References | PDF (279.9 KB)

740 Views
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Lubiprostone: pharmacokinetic, pharmacodynamic, safety and regulatory aspects in the treatment of constipation-predominant irritable bowel syndrome

Emanuel Raschi MD PhD & Fabrizio De Ponti (Professor) MD PhD

Pages: 293-305

Published online: 03 Jan 2014

AbstractforLubiprostone: pharmacokinetic, pharmacodynamic, safety and regulatory aspects in the treatment of constipation-predominant irritable bowel syndrome | Full Text | References | PDF (440.8 KB)

599 Views
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Research Article

Article

Page: i

Published online: 16 Jan 2014

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